Using the efficiency measurement indicators research in science and technology innovation team efficiency more and more gets the attention of the experts and scholars. Based on the science and technology innovation team operation stages production efficiency measurement indicators, this paper builds the scientific and technological innovation team innovation efficiency operating model, and puts forward the focus of the science and technology innovation team efficiency in team activity plan. In the process of science and technology innovation, team plan hypothesis is the focus of the exploration to practice using the method of research. Research bases on an enterprise headquarters and division of 18 science and technology innovation team as the research object, nodes in two time (3 months and 9 months after the beginning of the project) for the innovation of science and technology innovation activities efficiency in and the relationship between the innovation efficiency of field investigation. The results showed that 60% ~ 80% of the aggregation of teamwork plan is the essential factor of the innovation efficiency. In addition, the third month survey showed that team activity plan with hypothesis explore for the center influences the innovation efficiency greatly. The ninth month survey showed that team activity plan with practice for the center influences the innovation efficiency greatly. The study also verified the differences of team activities plan"s key point on the above two time nodes.