As a new type of open innovation and entrepreneurship incubator, university maker space gathers and matches the innovation and entrepreneurship resources inside and outside the university through the platform interface connection mechanism, and breaks the professional barriers and path dependence of innovation and entrepreneurship education in Colleges and universities. This paper is introducing platform theory to clarify the platform positioning and development strategy of university maker space. Which includes the evolution logic of "building the platform infrastructure - excitation network synergies - build platform ecosystem". It explores the construction of university maker space platform ecosystem that is deeply integrated with industry, with the critical path optimization in different stages, such as multi-dimensional structural embedding mechanism, multi-path interactive interface design, and multi-agent collaborative governance mechanism.