Agriculture is the foundation of China's economic development, and researches into algricultural infomatization construction have profounding impact on China's economic development. This paper uses the DEA method to build the input-output evaluation target system of agricultural informatization, with data from 31 provinces in the past 11 years (2005 ~ 2015). And conduct empirical analysis and efficiency evaluation. In this paper, 31 provinces are divided into four regions, including east, middle, west and northeast, to conduct comparative analysis. Researches show that: in the past 11 years, the overall efficiency of agricultural informatization in Central China is higher than the overall efficiency of other areas. The overall scale efficiency reached its optimal state in most years while there are a few years has redundancy of both input and output. Regions all over the country met the situation of redundancy of both input and output with scale income increasing in the earlier years. In the later years, the increasing of scale income are becoming slowly.