共查询到19条相似文献，搜索用时 187 毫秒
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利用非离子去污剂ＴｒｉｔｏｎＸ－１００抽提日本血吸虫成虫表膜蛋白，反相高效液相色谱（ＨＰＬＣ）分离纯化后，收集各主要蛋白峰，以１２５Ｉ标记的人血浆低密度脂蛋白（ＬＤＬ）作为放射性配基，通过放射性自显影初步鉴定表明日本血吸虫成虫表膜具有可与人血浆ＬＤＬ结合的受体蛋白。结果显示，低密度脂蛋白受体保留时间约为１１ｍｉｎ时，经ＳＤＳ－ＰＡＧＥ电泳鉴定其分子量约６００００，此蛋白能特异结合碘标记人血浆ＬＤＬ。本实验为了解血吸虫在宿主体内获得脂质的途径及进一步研制新的抗血吸虫药物打下基础。 相似文献
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目的：研究人群特异性免疫力对日本血吸虫感染率的影响。方法：选择粪检血吸虫阳性91人（A组）和粪检血吸虫阴性223人（B组）作为研究对象。两组人群经吡喹酮治疗后10d,将观察对象同时暴露在水稻栽插期,栽插期结束后30d用粪检查病,观察两组感染率是否有差异,以此推断特异性免疫力对人群血吸虫感染率的影响。结果：A组感染率（再感染率）为38．46％（35／91）,其中6—14岁儿童感染率（再感染率）为10．53％（2／19）,15～60岁人群感染率（再感染率）为45．83％（33／72）。B组的感染率为29．60％（66／223）,其中6～14岁儿童感染率为20．27％（15／74）,15～60岁人群感染率为34．23％（51／149）。结论：人体感染日本血吸虫后产生的特异性免疫力较弱,对降低人群再感染无明显作用。 相似文献
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在压电石英晶体金电极表面形成巯基丙酸(MPA)单分子膜、经NHS和EDC活化后固定血吸虫抗原(SjAg),研制成血吸虫抗体(SjAb)压电免疫传感器．研究测定了抗原价数及免疫反应平衡常数Kass,结果令人满意。 相似文献
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在压电石英晶体金电极表面形成MPA(疏基丙酸)单分子膜,经NHS和EDC活化后固定血吸虫抗原(SiAg),研制成血吸虫抗体(SjAb)压电免疫传感器。研究了包被抗原浓度、抗原抗体结合时间,TSM声波免疫传感的响应特性、重现性等实验条件的影响。压电晶体的频移值与IRS浓度在0～36μg/ml范围内有良好的线性关系,将此传感器用于兔抗血吸虫抗体血清样品的测定,结果令人满意。 相似文献
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杨水金 《商丘师范学院学报》1995,(Z4)
本文用固相反应法合成了新化合物Ｎａ（２４）Ｐ２Ｗ（２２）Ｏ（８３），并通过Ｘ射线衍射的测定，确定Ｎａ（２４）Ｐ２Ｗ（２２）Ｏ（８３）属正交晶系．其点阵常数为：ａ＝１．４７４５ｎｍ；ｂ＝１．１９３３ｎｍ；ｃ＝１．１１１９ｎｍ，ｚ＝２，属Ｐｚ１ｚ１ｚ１（Ｎ（０１９））空间群． 相似文献
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本文提出一种利用特征加权支持向量机（FWSVM）识别河流、湖泊等水域中血吸虫尾蚴的算法．该算法采用图像形态学、动态阈值化等图像处理方法在图片中搜索可能存在尾蚴的区域,然后利用疑似区域图像的Hu矩作为特征值训练FWSVM,最后利用训练好的分类器对采集的视频进行识别．实验结果表明该算法能够有效识别水域中的血吸虫尾蚴． 相似文献
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SAT问题（可满足性问题）是计算机科学的核心问题，研究SAT问题的方法很多，利用极小不可满足公式的性质来研究SAT问题是近几年兴起的一个热点研究方向．文章主要利用（1，＊）-消解和分裂方法研究了差为2的唯一极小不可满足公式集（Unique-MU（2））和差为2的对称极小不可满足公式集（SYM-MU（2））的结构和复杂度． 相似文献
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目的以衰老的自由基学说为依据,研究蚁皇浆口服液的抗衰老作用.方法52周龄小白鼠30只随机分为老龄实验组和老龄对照组,4周龄15只作为成年对照组,灌胃四周后分别取血测定SOD、CAT、Tch、TG和MDA等各项生化指标.结果老龄实验组SOD、CAT活性均明显升高(P＜0.01),MDA、Tch和TG含量明显降低(P＜0.01或P＜0.05).结论蚁皇浆口服液具有较强的抗氧化和抗衰老作用,是一种很有经济价值药食两用的保健品. 相似文献
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介绍了一种基于FPGA的可编程SONET OC-192 10 Gbit/s伪随机序列发生器和比特间插入奇偶校验码BIP-8的误码测试仪.该误码测试仪为并行反馈结构,可生成PRBS序列长度为27-1,210-1,215-1,223-1和231-1,通过SFI-4接口,采用10 Gbit/s收发一体光模块,其工作速率可达10 Gbit/s.在OC-192帧同步调整电路中,采用STM-64/OC192二分查找法的帧同步法,显著提高了帧同步速度并减少了帧同步逻辑的复杂度.该系统可作为一种低成本的测试仪评估OC-192-设备与器件,以取代昂贵的商用PRBS测试仪. 相似文献
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毛俊雯 《湖州师范学院学报》2000,(3)
以“统一模型”为理论基础,利用高速摄影机,对掺与不掺 Ｃａ＋＋之高氨酸铵（ＡＰ）晶体在带透明窗燃速仪中的爆燃进行了观测、分析,并初步讨论了Ｃａ＋＋的掺入对ＡＰ凝相反应的作用机理．研究表明,Ｃａ＋＋的掺入使ＡＰ晶体在固体火箭发动机经常工作的压强范围内压强指数降低,并在某一压强区段（实验中为７～８．５ＭＰａ）压强指数出现负值,这为进一步完善“统一模型”提供了依据,为负压强指数推进剂的研制和进一步降低硝胺／ＡＰ复合推进剂的压强指数提供了新的途径． 相似文献
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Quasi-phase-matching(QPM) periodical poled LiNbO3 （PPLN） is designed and successfully fabricated to enable second harmonic generation (SHG),The samples were Z-cut 0.5 mm thick and grating period is A=6.8 μm for the first order QPM of contimual wave λ=1.064μm which is emitted by Nd:YAG laser at room temperature 27℃,The output single-pass SHG power was tested by an authorized optical system.The normalized max conversion efficiency is calculated to be 0.25% (W.cm)^-1,The fabrication and parameters calculated method are introduced,and testing scheme is described in this paper,Even some ideas to improve conversion efficiency are offered. 相似文献
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Mohetaboer MOMIN 《Journal of Zhejiang University. Science. B》2012,13(8):638-644
Objective:To investigate the relationship between renal function and clinical outcomes among patients with acute ST-segment elevation myocardial infarction (ASTEMI), who were treated with emergency percutaneous coronary intervention (PCI). Methods: 420 patients hospitalized in Peking University First Hospital, diagnosed with ASTEMI treated with emergency (PCI) from January 2001 to June 2011 were enrolled in this study. Estimated glomerular filtration rate (eGFR) was used as a measure of renal function. We compared the clinical parameters and outcomes between ASTEMI patients combined renal insufficiency and the patients with normal renal function. Results:There was a significant increase in the concentrations of fibrinogen and D-Dimer (P<0.05) and a much higher morbidity of diabetes mellitus in the group of patients with chronic kidney disease (CKD; eGFR<60 ml/(min·1.73 m2)) (P<0.01). CKD (eGFR<60 ml/(min·1.73 m2)) was an independent predictor of in-hospital mortality for patients hospitalized with ASTEMI receiving PCI therapy rapidly (P=0.032, odds ratio (OR) 4.159, 95% confidence interval (CI) 1.127-15.346). Conclusions:Renal insufficiency is an independent predictor of in-hospital mortality for patients hospitalized with ASTEMI treated with primary PCI. 相似文献
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采用硒（Ⅳ）-KI-结晶紫显色体系,在酸性条件下,硒（Ⅳ）-KI-结晶紫体系发色快,显色灵敏度高,线形范围宽。显色体系反应机理为硒（Ⅳ）在酸性介质中定量的与I^-作用,得到体积较大的I3^-离子再与结晶紫大阳离子形成有色缔合物。在一定硒浓度范围内,缔合物吸光度与硒浓度成正比,由此可定量测定硒。 相似文献
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Xi-ping ZHANG Guang-hua FENG Jie ZHANG Yang CAI Hua TIAN Xiao-feng ZHANG Yi-feng ZHOU Zhi-wei WANG Ke-yi WANG 《Journal of Zhejiang University. Science. B》2009,10(3)
Objective: To investigate the therapeutic effects and mechanisms of Salvia miltiorrhizae (Danshen) in the treatment of severe acute panereatitis (SAP)- or obstructive jaundice (OJ)-induced heart injury. Methods: A total of 288 rats were used for SAP-(n=108) and O J-associated (n=180) experiments. The rats were randomly divided into sham-operated, model control, and Salvia miltiorrhizae-treated groups. According to the difference of time points after operation, SAP rats in each group were subdivided into 3, 6 and 12 h subgroups (n=12), whereas OJ rats were subdivided into 7, 14, 21, and 28 d subgroups (n=15). At the corre-sponding time points after operation, the mortality rates of the rats, the contents of endotoxin and phospholipase A2 (PLA2) in blood, and pathological changes of the hearts were investigated. Results: The numbers of dead SAP and OJ rats in the treated groups declined as compared with those in the model control group, but not significantly (P>0.05). The contents ofendotoxin (at 6 and 12 h in SAP rats and on 7, 14, 21, and 28 d in OJ rats, respectively) and PLA2 (at 6 and 12 h in SAP rats and on 28 d in OJ rats, respectively) in the treated group were significantly lower than those in the model control group (P<0.01 and P<0.001, respec-tively). Besides, myocardial pathological injuries were mitigated in SAP and OJ rats. Conclusion: In this study, we found that Salvia miltiorrhizae improved myocardial pathological changes, reduced the content of PLA2 in blood, and decreased the mortality rates of SAP and OJ rats, exerting protective effects on the hearts of the rats. 相似文献
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You-qun HUANG Rong GOU Yong-shu DIAO Qing-hua YIN Wen-xing FAN Ya-ping LIANG Yi CHEN Min WU Li ZANG Ling LI Jing ZANG Lu CHENG Ping FU Fang LIU 《Journal of Zhejiang University. Science. B》2014,15(1):58-66
Our intent is to examine the predictive role of Charlson comorbidity index （CCI） on mortality of patients with type 2 diabetic nephropathy （DN）. Based on the CCI score, the severity of comorbidity was categorized into three grades： mild, with CCI scores of 1-2; moderate, with CCI scores of 3-4; and severe, with CCI scores 〉5. Factors influencing mortality and differences between groups stratified by CCI were determined by logistical regression analysis and one-way analysis of variance （ANOVA）. The impact of CCI on mortality was assessed by the Kaplan- Meier analysis. A total of 533 patients with type 2 DN were enrolled in this study, all of them had comorbidity （CCI score 〉1）, and 44.7% （238/533） died. The mortality increased with CCI scores： 21.0% （50/238） patients with CCI scores of 1-2, 56.7% （135/238） patients with CCI scores of 3-4, and 22.3% （53/238） patients with CCI scores 〉5. Logistical regression analysis showed that CCI scores, hemoglobin, and serum albumin were the potential predictors of mortality （P〈0.05）. One-way ANOVA analysis showed that DN patients with higher CCI scores had lower levels of hemoglobulin, higher levels of serum creatinine, and higher mortality rates than those with lower CCI scores. The Kaplan-Meier curves showed that survival time decreased when the CCI scores and mortality rates went up. In con- clusion, CCI provides a simple, readily applicable, and valid method for classifying comorbidities and predicting the mortality of type 2 DN. An increased awareness of the potential comorbidities in type 2 DN patients may provide insights into this complicated disease and improve the outcomes by identifying and treating patients earlier and more effectively. 相似文献
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在0．1mol／LHAc—NaAc缓冲溶液(pH=4．54)中，用循环伏安法可得到维生素B12的两个还原峰。峰电位EP1=-0．458V，EP2=-0．831V(vs．SCE)。实验表明，维生素B12在玻碳电极上的电极过程为一受吸附控制的不可逆过程。测得还原峰的电子转移系数为0．3，标准速率常数为ks=2．40s^-1。用该法测定了维生素B12针剂中维生素B12的含量，结果与标示含量相吻合。 相似文献