共查询到19条相似文献，搜索用时 517 毫秒
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由于基因组计划的进展 ,基因组学的研究已从结构基因组学转向功能基因组学。文章介绍了几种大规模分析基因功能的新技术和新方法 ,包括微点阵、基因表达系列分析 (SAGE)、蛋白质组、生物信息学等 相似文献
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王子迎 《安徽教育学院学报》2008,26(3)
卵菌是一类真核生物,包括许多植物病原菌,引起许多作物、花卉等发生灾难性病害.卵菌具有独特分类地位的群体,由于表现出丝状等特性传统上被划分到真菌界中.近年来,随着基因组学理论和技术的发展,大量的卵菌基因组相关的数据库被建立.本文综述了现有的卵菌基因组资源以及卵菌分子遗传学的研究进展.重点论述了卵菌基因组的大小、组成和不稳定性以及卵菌的基因结构与功能基因组等五个方面,并分析了卵菌基因组的特点. 相似文献
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Jordan Bartol 《Science & Education》2013,22(10):2529-2546
Personalized genomics companies (PG; also called ‘direct-to-consumer genetics’) are businesses marketing genetic testing to consumers over the Internet. While much has been written about these new businesses, little attention has been given to their roles in science communication. This paper provides an analysis of the gene concept presented to customers and the relation between the information given and the science behind PG. Two quite different gene concepts are present in company rhetoric, but only one features in the science. To explain this, we must appreciate the delicate tension between PG, academic science, public expectation, and market forces. 相似文献
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Elena L. Grigorenko 《Mind, Brain, and Education》2007,1(1):20-27
ABSTRACT— This article offers some thoughts on possible connections between genomics and education. Genomics is already revolutionizing the way medical care is delivered and distributed; it will inevitably affect children's developmental trajectories by introducing more pharmacological and behavioral therapies. Educators should be prepared to understand the effect of these changes on children in the classroom, where children around the world spend a large portion of their formative years. Educators should also be prepared to understand the current advances in genomics and be able to discuss them with the parents and health care providers of their students. 相似文献
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Bridging the Gap Between Genomics and Education 总被引：1，自引：0，他引：1
ABSTRACT— Despite several decades of research suggesting the importance of both genetic and environmental factors, these findings are not well integrated into the larger educational literature. Following a discussion of quantitative and molecular genetic methods, this article reviews behavioral genetic findings related to cognitive and academic skills. This literature suggests that (a) the relative importance of genes and environments varies developmentally; (b) genetics, and to a lesser extend the environment, account for a substantial portion of the covariance within and across academic domains; and (c) some forms of disability are qualitatively different from the population, whereas others constitute the lower end of a continuum of ability. Following a discussion of the strengths and limitations of current behavioral genetic research and intervention research, we then discuss the ways in which understanding gene–environment interplay can be used to develop better definitions of learning impairment and better explain the substantial variability in response to intervention. 相似文献
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植物基因组的研究已经由以全基因组测序为目标的结构基因组学转向以基因功能鉴定为目标的功能基因组学研究.植物功能基因组学研究是利用结构基因组学积累的数据,从中得到有价值的信息,阐述DNA序列的功能,从而对所有基因如何行使其职能并控制各种生命现象的问题作出回答.近年来植物功能基因组学的研究技术主要包括表达序列标签、基因表达的系列分析、DNA微阵列和反向遗传学等.对植物功能基因组学的研究将有利于我们对基因功能的理解和对植物形状的定性改造和利用. 相似文献
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植物功能基因组学研究 总被引：5，自引：0，他引：5
基因组研究已进入了以功能基因组研究为特征的后基因组时代.本文介绍了基因组及基因组学的概念及功能基因组学的研究方法,并综述了植物功能基因组学的研究进展. 相似文献
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Weatherall D 《Journal of Zhejiang University. Science. B》2006,7(2):161-161
The completion of the human genome project was accompanied by quite remarkable claims about the benefits for health that would follow this out-standing scientific endeavour.In this short article,I shall try to put some of these claims into perspective.Currently,the poorer countries of the world are still suffering from the effects of malnutrition,ineffective healthcare systems,and the scourges of tuberculosis,malaria,and HIV/AIDS.The richer countries are attempting to deal with the costs of… 相似文献
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The growing importance of genomics and bioinformatics methods and paradigms in biology has been accompanied by an explosion of new curricula and pedagogies. An important question to ask about these educational innovations is whether they are having a meaningful impact on students’ knowledge, attitudes, or skills. Although assessments are necessary tools for answering this question, their outputs are dependent on their quality. Our study 1) reviews the central importance of reliability and construct validity evidence in the development and evaluation of science assessments and 2) examines the extent to which published assessments in genomics and bioinformatics education (GBE) have been developed using such evidence. We identified 95 GBE articles (out of 226) that contained claims of knowledge increases, affective changes, or skill acquisition. We found that 1) the purpose of most of these studies was to assess summative learning gains associated with curricular change at the undergraduate level, and 2) a minority (<10%) of studies provided any reliability or validity evidence, and only one study out of the 95 sampled mentioned both validity and reliability. Our findings raise concerns about the quality of evidence derived from these instruments. We end with recommendations for improving assessment quality in GBE. 相似文献
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本文介绍了转座子的基本结构和转座子标签技术分离基因的基本原理、方法;并就转座子标签技术的研究新进展,转座子标签技术在水稻功能基因组学研究中的应用等方面进行了综述. 相似文献
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Mary Rafter Robyn M. Gillies 《International Journal of Disability, Development & Education》2018,65(1):45-56
Recent developments in genomic-based knowledge is challenging educators to learn more about the early precursors of various difficulties children experience in learning and how they can use this information to identify preventative strategies or strategies that minimise their effect. The purpose of this article is to provide a brief outline of what is already known about some genetic disorders and some other disorders currently identified in the genome, the role of the teacher in understanding individual student needs, and how teachers can address some of the challenges posed. This article is fundamentally a review of the literature concerning genomics and genomic literacy and the implications for teachers in regular classes. 相似文献
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《教育教学论坛》2022,(16)
随着DNA测序技术的快速发展,以基因组为代表的组学技术在农林类院校生物学相关的研究中越来越受到重视,逐渐成为必备的研究方法和手段。然而,目前直接从事相关研究的大部分研究生一般具有生物学背景,缺乏与组学相关的背景知识和思维方式,导致组学技术的推广与应用受到较大限制。研究生公选课程“基因组学前沿专题”旨在为具有生物学背景的低年级硕士、博士研究生提供以基因组学为中心的多组学的理论基础、应用场景以及分析技术原理等,帮助学生快速建立组学相关的研究意识,促进组学的理念和技术服务于后续的研究课题。在本课程中,通过课堂教学和讨论报告相结合的方式,可增进学生和教师之间的交流,激发学生学习的积极性和主动性,加强学生对基因组学相关原理和分析方法的了解,并将其作为一种手段和方法,促进适用于农林类生物学的研究,满足现代社会对创新型人才的需求。 相似文献
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Barbara Mirel Anuj Kumar Paige Nong Gang Su Fan Meng 《Journal of Science Education and Technology》2016,25(1):91-110
Life scientists increasingly use visual analytics to explore large data sets and generate hypotheses. Undergraduate biology majors should be learning these same methods. Yet visual analytics is one of the most underdeveloped areas of undergraduate biology education. This study sought to determine the feasibility of undergraduate biology majors conducting exploratory analysis using the same interactive data visualizations as practicing scientists. We examined 22 upper level undergraduates in a genomics course as they engaged in a case-based inquiry with an interactive heat map. We qualitatively and quantitatively analyzed students’ visual analytic behaviors, reasoning and outcomes to identify student performance patterns, commonly shared efficiencies and task completion. We analyzed students’ successes and difficulties in applying knowledge and skills relevant to the visual analytics case and related gaps in knowledge and skill to associated tool designs. Findings show that undergraduate engagement in visual analytics is feasible and could be further strengthened through tool usability improvements. We identify these improvements. We speculate, as well, on instructional considerations that our findings suggested may also enhance visual analytics in case-based modules. 相似文献
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《CBE life sciences education》2010,9(1):55-69
Genomics is not only essential for students to understand biology but also provides unprecedented opportunities for undergraduate research. The goal of the Genomics Education Partnership (GEP), a collaboration between a growing number of colleges and universities around the country and the Department of Biology and Genome Center of Washington University in St. Louis, is to provide such research opportunities. Using a versatile curriculum that has been adapted to many different class settings, GEP undergraduates undertake projects to bring draft-quality genomic sequence up to high quality and/or participate in the annotation of these sequences. GEP undergraduates have improved more than 2 million bases of draft genomic sequence from several species of Drosophila and have produced hundreds of gene models using evidence-based manual annotation. Students appreciate their ability to make a contribution to ongoing research, and report increased independence and a more active learning approach after participation in GEP projects. They show knowledge gains on pre- and postcourse quizzes about genes and genomes and in bioinformatic analysis. Participating faculty also report professional gains, increased access to genomics-related technology, and an overall positive experience. We have found that using a genomics research project as the core of a laboratory course is rewarding for both faculty and students. 相似文献
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《CBE life sciences education》2014,13(4):711-723
In their 2012 report, the President''s Council of Advisors on Science and Technology advocated “replacing standard science laboratory courses with discovery-based research courses”—a challenging proposition that presents practical and pedagogical difficulties. In this paper, we describe our collective experiences working with the Genomics Education Partnership, a nationwide faculty consortium that aims to provide undergraduates with a research experience in genomics through a scheduled course (a classroom-based undergraduate research experience, or CURE). We examine the common barriers encountered in implementing a CURE, program elements of most value to faculty, ways in which a shared core support system can help, and the incentives for and rewards of establishing a CURE on our diverse campuses. While some of the barriers and rewards are specific to a research project utilizing a genomics approach, other lessons learned should be broadly applicable. We find that a central system that supports a shared investigation can mitigate some shortfalls in campus infrastructure (such as time for new curriculum development, availability of IT services) and provides collegial support for change. Our findings should be useful for designing similar supportive programs to facilitate change in the way we teach science for undergraduates. 相似文献
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Valerie W. Hu 《Child development》2013,84(1):89-103
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that affect an estimated 1 in 110 individuals. Although there is a strong genetic component associated with these disorders, this review focuses on the multifactorial nature of ASD and how different genome‐wide (genomic) approaches contribute to our understanding of autism. Emphasis is placed on the need to study defined ASD phenotypes as well as to integrate large‐scale “omics” data in order to develop a “systems‐level” perspective of ASD, which in turn is necessary to allow predictions regarding responses to specific perturbations and interventions. 相似文献