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1.
高脂血症病人血液流变学指标的测定 总被引：1，自引：0，他引：1
本文对９７例健康人与４４例高脂血症病人进行血液流变学等１０项指标的测定与比较，实验结果证明，高脂血症病人的全血粘度（２３０．００ｓ＾－１，２３．００ｓ＾－１，９．６０ｓ＾－１），血浆粘度（２３０．００ｓ＾－１），纤维蛋白原等均明显高于健康人，经统计学处理（Ｐ＜０．０１），有显著差异。 相似文献
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目的探讨氨力农与厄贝沙坦联合治疗慢性肺源性心脏病心力衰竭的临床疗效。方法选择76例慢性肺源性心脏病心力衰竭患者随机分为两组,即治疗组和对照组。对照组按需给予吸氧、抗感染、平喘祛痰、改善通气及纠正水电解质酸碱平衡紊乱等常规治疗,必要时给予洋地黄类药物。治疗组在常规治疗基础上加用氨力农联合厄贝沙坦治疗,疗程10～14天。治疗前、后分别观察患者的临床表现,进行心功能（NYHA分级）评估,行血生化、肝肾功能、心电图、彩色多普勒超声测定肺动脉压（PAP）等检查。结果疗程结束后,治疗组PaCO2、PAP明显降低、PaO2显著升高,与对照组相比有显著性差异（P值〈0.05）。治疗组总有效率为92.1.%,对照组为63.2%,差异有显著性。结论氨力农与厄贝沙坦联合治疗慢性肺源性心脏病心力衰竭安全有效。 相似文献
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4.
观察了力平脂对高脂血症者的治疗作用和安全性．确诊高脂血症者６８例，力平脂，０．１，Ｔｉｄ，服一个月为一疗程后，血清总胆固醇（ＴＣ）平均降低２０．９８％，甘油三酯平均降低５１．８８％，ＨＤＬ－Ｃ平均升高１０．２６％，ＬＤＬ－Ｃ平均降低１２．５７％，ＡｐｏＡ１平均升高２．２４％，ＡｐｏＢ平均降低２１．１０％，从调血脂的个体疗效分析，力平脂降低ＴＣ的总有效率８４．６１％，降低ＴＧ的总有效率９５．２４％，升高ＨＤＬ－Ｃ的总有效率６１．７７％，降低ＬＤＬ－Ｃ的总有效率为５５．８８％，升高ＡｐｏＡ１的总有效率３８．２４％，降低ＡｐｏＢ的总有效率７７．９４％．提示：力平脂治疗高脂血症者，对降低ＴＣ，ＴＧ，ＬＤＬ－Ｃ，ＡｐｏＢ和升高ＨＤＬ－Ｃ，ＡｐｏＡ１均有明显效果，其中降低ＴＧ的疗效尤为突出，副作用轻微．临床实践表明：力平脂是一个疗效高、安全、服用方便的调血脂新药 相似文献
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目的 观察诺迪康胶囊治疗椎基底动脉供血不足的疗效。方法将椎基底动脉供血不足患者60例随机分为诺迪康治疗组（30例）和对照组（30例）,两组采用相同的综合治疗方法,均采用香丹注射液10ml,加入5％葡萄糖或0．9％氯化钠500ml中静脉滴注,每日1次;治疗组加用诺迪康胶囊每次2粒,每日3次,口服;疗程约4周。对两组疗效进行对比分析,并观察,治疗组治疗前后经颅多普勒检查变化情况。结果①治疗组总有效28例,总有效率为93％。对照组总有效25例,总有效率83％。两组总有效率比较差异有显著性（P〈0．05）。②治疗组治疗前后比较椎基底动脉平均血流速度的变化差异亦具有显著性（P〈0．05）。结论诺迪康胶囊能改善脑供血,并显著增加脑血流量;说明诺迪康胶囊治疗椎基底动脉供血不足安全而有效。 相似文献
6.
目的：观察脑安胶囊治疗中风恢复期气虚血瘀型的临床疗效。方法：将中风恢复期气虚血瘀型患者76例随机分治疗组39例和对照组37例,对照组给予常规对症治疗,包括抗凝,抗血小板聚集,脑保护,控制血糖、血压等;治疗组在常规治疗的同时给予脑安胶囊口服2# bid,连续治疗30d。观察治疗前后2组患者临床疗效和神经功能缺损（NDS）评分变化情况。结果：治疗组显著进步率（61.6％）及总进步率（94.9％）均分别高于对照组显著进步率（32.4％）及总进步率（75.7％）,两组差异有统计学意义（P＜0.05）。两组治疗后神经功能缺损评分均下降,而治疗组NDS评分下降优于对照组（P＜0.05）。结论：脑安胶囊在治疗中风恢复期气虚血瘀型疗效肯定。 相似文献
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《大众科技》2020,(4)
目的:观察耳穴压豆配合情志护理对周围性面瘫患者焦虑心理的影响。方法:将60例周围性面瘫患者由随机数据生成器软件随机分成观察组30例和对照组30例。对照组采用情志护理方法,观察组在情志护理的基础上配合耳穴压豆疗法,耳穴选择:神门、心、肝、肾、胃、皮质下、交感、颞。按压3min/穴/次,早、中、晚各2次。双侧耳廓交替进行,2 d更换1次,6 d为1疗程,每个疗程休息1 d,连续治疗2个疗程。观察两组治疗后的焦虑自评量表(SAS评分)差异变化情况。结果:观察组与对照组在治疗后的SAS评分低于治疗前(P0.05),观察组治疗后的SAS评分相较对照组下降更为显著(P0.05)。结论:耳穴压豆配合情志护理能有效缓解周围性面瘫患者的焦虑心理,值得在日常的护理工作中广泛地运用。 相似文献
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目的：观察利巴韦林、更昔洛韦治疗儿童传染性单核细胞增多症（IM）（简称传单）的疗效对比。方法：70例传单患儿随机分为对照组和治疗组。两组患儿在常规治疗的基础上,对照组35例给予利巴韦林10mg／kg／d,治疗组35例给予更昔洛韦10mg／kg／d,均静脉滴注,疗程均为7～10天。结果：治疗组总有效率达94．29％,明显高于对照组68．57％,（P〈0．01）;治疗组热程、咽峡炎改善时间、淋巴结缩小时间、肝脾回缩时间、平均住院时间、变异淋巴细胞恢复至〈10％的时间均较对照组明显缩短（P〈0．01或P〈0．05）。结论：更昔洛韦治疗儿童传单较传统的利巴韦林疗效好,值得推广。 相似文献
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《西藏科技》2017,(9)
目的主要探讨藏西医结合来治疗人体消化性溃疡的临床疗效。方法自2012年2月1号至2015年12月30期间,对于比较符合纳入标准的消化性溃疡(PU)患者人数30为例,其中对于对照组(单纯西医组)15例给予单纯的西药:埃索美拉唑、阿莫西林胶囊、克拉霉素片三联用药,对于另外的治疗组(藏西医结合组)15例在对照组一的基础上给予藏药口服,藏药口服治疗的方法是凌晨常觉和芒觉交替服2克,在中午,二十五味大汤丸2克口服,服2周,在治疗期间详细记录患者的临床症状变化,并对他们的各种征象及治疗效果进行分析。结果治疗组(藏西医结合组)临床症状改善情况均优于对照组(单纯西医组),两组治疗组均能改善消化性溃疡临床症状如:胃部疼痛、腹胀、嗳气、反酸、上腹部不适等伴随症状基本消失。胃镜复查时发现治疗组(藏西医结合组)中8例胃溃疡有7例愈合,7例十二脂肠溃疡,6例全部愈合,愈合率86%。对照组(单纯西医组)中8例胃溃疡有6例愈合,7例十二脂肠溃疡,6例全部愈合,愈合率80%。结论藏西医结合治疗消化性溃疡的治疗效果优于单纯西药治疗。 相似文献
10.
报告１０８例病毒性肝炎患者血清总补体（ＣＨ＿（５０））和Ｃ＿３值的检测结果：急性肝炎的ＣＨ＿（５０）为６８．４±６．１３单位／ｍｌ，Ｃ＿３为１３０．２±６．６７ｍｇ％，均高于正常组（ＣＨ＿（５０）为４８．５±５．７５单位／ｍｌ，Ｃ＿３为１０２±５ｍｇ％），Ｐ＜０．０１；其他类型的肝炎患者组的补体均低于正常组，Ｐ＜０．０１．补体的含量与Ｔ细胞花环（Ｅｔ花环）呈中度相关，与ＧＰＴ呈高度相关，因此测定ＣＨ＿（５０）和Ｃ＿３可作为衡量患者机体免疫功能和判断病毒性肝炎预后的指标之一。 相似文献
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This study suggests a new erythrocyte sedimentation rate (ESR) measurement method for the biophysical assessment of blood by using a microfluidic device. For an effective ESR measurement, a disposable syringe filled with blood is turned upside down and aligned at 180° with respect to gravitational direction. When the blood sample is delivered into the microfluidic device from the top position of the syringe, the hematocrit of blood flowing in the microfluidic channel decreases because the red blood cell-depleted region is increased from the top region of the syringe. The variation of hematocrit is evaluated by consecutively capturing images and conducting digital image processing technique for 10 min. The dynamic variation of ESR is quantitatively evaluated using two representative parameters, namely, time constant (λ) and ESR-area (AESR). To check the performance of the proposed method, blood samples with various ESR values are prepared by adding different concentrations of dextran solution. λ and AESR are quantitatively evaluated by using the proposed method and a conventional method, respectively. The proposed method can be used to measure ESR with superior reliability, compared with the conventional method. The proposed method can also be used to quantify ESR of blood collected from malaria-infected mouse under in vivo condition. To indirectly compare with the results obtained by the proposed method, the viscosity and velocity of the blood are measured using the microfluidic device. As a result, the biophysical properties, including ESR and viscosity of blood, are significantly influenced by the parasitemia level. These experimental demonstrations support the notion that the proposed method is capable of effectively monitoring the biophysical properties of blood. 相似文献
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Shivananda Nayak Arun Maiya Manjunath Hande 《Indian journal of clinical biochemistry : IJCB》2005,20(1):47-51
The role of treadmill exercise on blood glucose homeostasis in noninsulin dependent diabetes mellitus (NIDDM) were studied
using males between age of 45 and 60 years (X-52), who were clinically and biochemically-confirmed cases of NIDDM were taken
into study group. Control group comprised of 10 males between age group of 45 to 60 (X-53) years. All the subjects were assessed
by physician and were investigated to confirm diabetic status. The whole study period was extended for 6 weeks. The significant
decrease in postprandial blood sugar (44.4 mg% for the study group and 32.2mg% for the control group) with a significant inter
group difference (P<0.05) was observed. The mean decrease in fasting blood sugar (39.4mg% for the study group and 27.4mg%
for the control group), with a marginal inter group difference (P<0.05) was observed. The treadmill exercise was found to
be a definite tool in addition to drug and diet in glycemic control. 相似文献
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目的:探讨葛根汤治疗重度子痫前期的临床疗效。方法:对广西中医药大学第一附属医院2013年6月至2016年1月收治的早发型重度子痫前期病人80例,采用随机数字表法随机分为A(研究组)和B(对照组)。对照组常规用解痉药硫酸镁、降压药硝苯地平治疗,研究组除常规治疗,加用葛根汤治疗。观察两组治疗后平均动脉压、24h尿蛋白量、脐动脉血流阻力、全血粘度、D-二聚体;终止妊娠时新生儿体重、新生儿窒息例数及延长孕龄时间;两组母儿并发症(包括:胎盘早剥、肝肾功能损害、心衰肺水肿、脑血管意外、DIC、胎儿窘迫等)例数等指标。结果:A组治疗后平均动脉压、24h尿蛋白量、脐动脉血流阻力、全血粘度、D-二聚体均明显低于B组,差异均具有统计学意义(P0.01);A组胎儿窘迫例数比B组少(P0.05),A组治疗后延长孕龄时间比B组长(P0.01),差异均具有统计学意义。A组新生儿体重比B组大,新生儿窒息例数比B组少,但差异均无统计学意义(P0.05)。结论:葛根汤治疗早发型重度子痫前期临床疗效确切,值得推广。 相似文献
14.
对５６例消化性溃疡患者，平分两组分别用奥美拉唑及进口洛赛克治疗４周。结果：奥美后唑总有效率９６％，洛赛克１００％，两者差异无显著性；两组治疗前后快速尿素酶试验阳性率相比差异无显著性；治疗前与治疗后胃液ｐＨ值相比两组差异均有高度显著性。奥美拉唑费用低，有推广价值。 相似文献
15.
目的:观察参附注射液联合西药治疗急性左心衰竭(Acute heart failure,AHF)的临床疗效。方法:选择AHF患者150例,随机分为对照组和治疗组,对照组给予单纯西药治疗,治疗组在对照组用药的基础上加用参附注射液50ml/d静滴。疗程为10天。结果:治疗组总有效率93.3%,明显高于对照组(P0.05)。两组疗后肺部湿啰音均明显减少,而经疗后的组间比较,治疗组的中医证候积分、脑钠肽和左室射血分数改善更显著(P0.05),结论:参附注射液联合西药治疗AHF的疗效比单用西药疗效更佳,值得在临床上推广应用。 相似文献
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Bhalla Kapil Shukla Rimi V. P. Gupta S. Pugazhenthi K. M. Prabhu 《Indian journal of clinical biochemistry : IJCB》1995,10(2):57-61
In the present study, 58 diabetic patients (type II) comprising uncomplicated (27) and complicated (31) cases along with 38 healthy matched controls were investigated for glycosylated hemoglobin (HbA1), glycosylated serum proteins (GSP) and serum lipid profile viz. triacylglycerol, total cholesterol, HDL-cholesterol (HDL-C), VLDL-C, LDL-C and their ratios. HbA1 and GSP were significantly elevated in diabetic group as a whole when compared with controls (p<0.01), but comparison of mean values of complicated and uncomplicated group revealed (though higher in complicated) that the difference between two groups was not statistically significant (p>0.05). Follow-up studies showed that while GSP levels reflect variations in blood glucose over a shorter period of 15 days, those of HbA1 do so for about 3 months. HbA1 correlated with fasting blood glucose (p<0.01), whereas GSP showed correlation with both fasting (p<0.01) and postprandial (p<0.05) blood glucose. Hypercholesterolemia and hypertriacylglycerolemia were observed (p<0.01) in both the groups. However no significant change was seen in HDL-C (p>0.05) even after accounting for sex in both the groups. Interestingly TC:HDL-C was elevated significantly (p<0.01) in the above groups. These findings seem to suggest that at the levels of hyperglycemia, hypercholesterolemia and hypertriacylglycerolemia observed, some patients are prone to develop complications earlier. 相似文献
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Svjetlana Karabuva Vedran Carevi? Mislav Radi? Damir Fabijani? 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2013,23(3):351-359
Aim:
The aim of study was to: 1) examine the relationship between ABO blood groups and extent of coronary atherosclerosis in patients with chronic coronary artery disease (CAD), 2) compare ABO blood groups distribution in CAD patients and general population, 3) examine possible differences in traditional risk factors frequency in CAD patients with different ABO blood groups.Materials and methods:
In the 646 chronic CAD patients (72.4% males) coronary angiograms were scored by quantitative assessment using multiple angiographic scoring system, Traditional risk factors were self reported or measured by standard methods. ABO blood distribution of patients was compared with group of 651 healthy blood donors (74.6% males).Results:
Among all ABO blood group patients there was no significant difference between the extent of coronary atherosclerosis with regard to all the three scoring systems: number of affected coronary arteries (P = 0.857), Gensini score (P = 0.818), and number of segments narrowed > 50% (P = 0.781). There was no significant difference in ABO blood group distribution between CAD patients and healthy blood donors. Among CAD patients, men with blood group AB were significantly younger than their pairs with non-AB blood groups (P = 0.008). Among CAD patients with AB blood group, males < 50 yrs were significantly overrepresented when compared with the non-AB groups (P = 0.003).Conclusions:
No association between ABO blood groups and the extent of coronary atherosclerosis in Croatian CAD patients is observed. Observation that AB blood group might possibly identify Croatian males at risk to develop the premature CAD has to be tested in larger cohort of patients. 相似文献18.
国产托拉塞米片治疗原发性高血压的疗效观察 总被引：2，自引：0，他引：2
目的观察国产托拉塞米片治疗原发性高血压的疗效和安全性.方法采用双盲、随机平行对照,以托拉塞米片为验证组,吲哚帕胺片为对照,观察44例原发性高血压患者2周到8周的降压疗效及安全性.结果 4周降压总有效率验证组为83.33%,对照组72.58%;显效率验证组为22.22%,对照组为29.03%,验证组和对照组降压疗效比较无统计学差异(P>0.05).服用后8周实验药对肝肾功能、血尿常规及心电图均无明显影响.结论托拉塞米是一种安全有效的原发性高血压治疗药物. 相似文献