共查询到20条相似文献，搜索用时 375 毫秒
1.
Syed Mazher Husain M. P. J. S. Anandaraj 《Indian journal of clinical biochemistry : IJCB》1995,10(2):122-125
Hemoglobin E (beta-26Glutamic acid→Lysine) is the second most prevalent hemoglobin variant in the world. 293 blood samples from cases referred from several hospitals in the region of Andhra Pradesh were screened for the detection of hemoglobinopathies. Four samples were found to be in heterozygous state for Hb E condition. Mutation in two of these heterozygotes was analysed using a 722 base pair (bp) amplified DNA fragment from beta-globin gene and restriction enzyme Mnl 1. A 232bp DNA fragment was found to be associated with the Hb E mutation. 相似文献
2.
M. Swarna A. Jyothy P. Usha Rani P. P. Reddy 《Indian journal of clinical biochemistry : IJCB》2003,18(2):102-105
Three thousand cases with mental retardation referred from different hospitals were screened for aminoacid disorders. Among
them one case of hyperprolinuria and another case of hyperprolinuria with hyper hydroxyprolinuria were detected. These are
the first cases to be reported from the state of Andhra Pradesh. 相似文献
3.
In recent years, many different types of e-government projects have been implemented across the developing world. One important application area, especially following the Millennium Development Goals, is the introduction of health information systems to improve the management of health care for development. Despite significant investments in these projects, experience reveals a disjuncture between macro-level policy priorities and micro-level implementation of these programmes. We use a broad conceptualization of evaluation to synthesize priorities at different levels during the implementation of an e-government project—the Health Information Systems Project (HISP) in Andhra Pradesh, India. This enables us to identify important enabling processes and conditions which serve to connect policy and implementation priorities. Our findings suggest that evaluation does help us to understand the disjuncture between policy at the macro level and implementation at the micro level and to identify linkages between the two. Finally, we discuss some of the key institutional issues that need to be addressed to translate the learning derived from the field into policy actions. 相似文献
4.
In recent years, many different types of e-government projects have been implemented across the developing world. One important application area, especially following the Millennium Development Goals, is the introduction of health information systems to improve the management of health care for development. Despite significant investments in these projects, experience reveals a disjuncture between macro-level policy priorities and micro-level implementation of these programmes. We use a broad conceptualization of evaluation to synthesize priorities at different levels during the implementation of an e-government project—the Health Information Systems Project (HISP) in Andhra Pradesh, India. This enables us to identify important enabling processes and conditions which serve to connect policy and implementation priorities. Our findings suggest that evaluation does help us to understand the disjuncture between policy at the macro level and implementation at the micro level and to identify linkages between the two. Finally, we discuss some of the key institutional issues that need to be addressed to translate the learning derived from the field into policy actions. 相似文献
5.
B. Venkata Raman D. N. Rao T. M. Radhakrishnan 《Indian journal of clinical biochemistry : IJCB》2004,19(1):105-109
Enteromorpha compressa a marine green algal species grows extensively in North coastal Andhra Pradesh. Besides its nutritional importance it has
also been identified as source of anti-anaphylactic compound(s).E. compressa extracts alleviated the IgE levels raised against ovalbumin and other allergens in mice. Further,Enteromorpha extract also significantly down regulated the serum IgE levels in different murine models irrespective of their genetic background.
The results obtained in this study suggest thatE. compressa extract has compound(s), which inhibit IgE immune response and may have potential in curing various types of allergies. 相似文献
6.
Ramesh Srinivasan 《The Information Society》2013,29(1):24-36
Research exploring the means by which new media technologies can shape development within marginalized communities worldwide has began to move away from discussion limited to technical and infrastructural, to consider the interactions, beliefs, and values of local communities. Yet most projects continue to focus on enabling communities to access external information, rather than on the possibility of using media to catalyze community reflection and thereby developmental activity from within. This article shows how this promise can be actualized by providing an overview of an experimental project that made available a set of video cameras to a carefully selected group of community members in a ritualized, largely nonliterate village in Andhra Pradesh, India. It concludes that policymakers, researchers, and practitioners would benefit from considering the possibilities that reflective media hold to generate collective action and consensus building, and that these possibilities can synergize with the need to develop scalable projects. 相似文献
7.
首先分别介绍了文件I/O和标准I/O库的相关函数和实现细节,提出了一系列有关文件读写效率的猜想,然后基于Linux平台设计实验并验证了提出的猜想,最后比较了文件I/O函数和标准I/O库函数,并总结了各自的适用场合。 相似文献
8.
The serum PSA is universally accepted as the useful and clinically relevant tumor marker for monitoring therapy and identifying
early recurrence in patients of carcinoma prostate throughout the world. However, application of serum PSA is limited to screening
for early adenocarcinoma prostate among males above fifty years of age.
Serum PSA concentration varies from one population to another in different parts of the world. Many groups of workers have
selected 4 ng/ml of serum PSA as upper limit of normal range without giving due consideration for age specific increase in
serum PSA. There is no single report available on normal decade wise age specific reference intervals for serum PSA in Indian
males.
The present study is undertaken to establish age specific reference intervals in healthy Indian males from 20–89 years belonging
to subpopulation of Andhra Pradesh from South India. Our results revealed lowest concentration of 95 percentile serum PSA
in Indian males compared to other populations globally. Contrary to this, healthy Afro Americans were found to have highest
concentration of serum PSA compared to all other populations. 相似文献
9.
I2(SInter-ICSoundBus)是飞利浦公司为数字音频设备之间的音频数据传输而制定的一种总线标准。文章介绍了基于ADSP的I2S总线的特点及其应用。在对I2S总线基本规范进行了介绍后,利用了I2S总线处理多音频通道的优势提出了一款实用音频系统。它可以通过软硬件配置,根据用户不同需要成为性能优异的家庭影院或四音轨家庭音频工作站。 相似文献
10.
11.
Simin Sohrabi Azim Akbarzadeh Dariush Norouzian Ali Farhangi Mehri Mortazavi Mohammad Reza Mehrabi Mohsen Chiani Zahra Saffari Soheil Ghassemi 《Indian journal of clinical biochemistry : IJCB》2011,26(4):354-359
The attempt is made to produce recombinant factor VIII but the first step in producing such product is production and purification
of rabbit’s polyclonal antibody against factor VIII. The second and third steps involve monoclonal antibody and recombinant
factor VIII production. Factor VIII is one of the most important coagulating factor where its deficiency leads to diseases
like hemophilia type A or classic. It is an inherited disease. Previously, it was obtained through fractionation of blood
plasma of blood donors. After processing, factor VIII could be used to manage such patients. Due to transfer of viral disease
like hepatitis and HIV through factor VIII obtained by fractionation, high cost of production, insufficiency of the donors
and the process of virus removal, thus production of factor VIII through recombinant technology can be useful and helpful.
The reaction between antibody and antigen is one the most specific reaction; therefore, such reaction can be employed to identify
factor VIII. Thereby, rabbits were injected several times with adjuvant-linked antigen to produce antibody. The antibody was
separated from the blood sample, purified and used to identify factor VIII in the research. 相似文献
12.
The incidence of cardiovascular and cerebrovascular disease is steadily increasing in South East Asian countries including
Indian sub continent. Many lipids, apolipoproteins and Lp (a) except HDL-C and apo A-I, A-II are implicated as risk factors
for coronary artery disease and cerebrovascular disease. There is great need to have national guidelines for each country
like the ATP III guidelines recommended for U.S. population. For recommending appropriate medical decision limits, it is mandatory
that each country establishes reference intervals pertaining to their population due to dietary, genetic and environmental
diversity. In the present study, reference intervals for serum lipids, apolipoproteins and Lp (a) were established in a total
of 1923 healthy Indian reference individuals comprising 1161 healthy men and 762 healthy women from Andhra Pradesh. For each
analyte viz., serum total cholesterol, HDL-C, LDL-C, triglycerides, Lp (a), Apo A-I, Apo A-II, B, C-II, C-III and E, mean,
two SD, median, confidence limits of mean, different percentile values are presented. The study also includes decade wise
changes in each analyte and comparison of lipids, lipoproteins and Lp (a) among few populations covering U.S., India, Japan,
Sweden, Finland and China. Reference Intervals for all lipid and lipoprotein parameters will immensely help in assessing associated
risk for cardiovascular and cerebrovascular diseases in India. Additionally, the results will be beneficial in formulating
our own guidelines pertaining to Indian population. 相似文献
13.
应用RAPD技术,沿一个海拔梯度研究了阿尔卑斯山黄花茅自然居群的遗传变异和分化。实验
表明,虽然在亚居群间有很少的亚居群独有遗传标记的存在,但通过RAPD资料的聚类分析、主因子分 析以及相关分析观察到遗传分化沿海拔梯度发生,而且亚居群间的遗传分化和它们的海拔高度(地理距 离)呈有意义的正相关。研究结果暗示,在阿尔卑斯山的高山-亚高山过渡区,亚居群间的海拔高度差别 可能导致黄花茅开花和生长物候期的变化,而后者限制了亚居群间的基因流,从而引起居群内的遗传分化。 相似文献
14.
对浙江南部沿海的6种舌鳎属鱼类线粒体12S rRNA序列进行扩增,得到长度约为346 bp的片段。利用MEG Aversion3.0软件分析了6种鱼类的序列特征,检测到100个变异位点,其中简约信息位点43个,插入缺失位点11个;平均A+T∶C+G为57.2%∶43.8%。所有序列的转换颠换比(TS/TV)为2.8,突变未达到饱和。并以鳎科的塞内加尔鳎作为外群,利用PAUP Version4.0 b10软件构建了NJ、MP、ML系统进化树。结果显示在3种进化系统树中6种舌鳎的拓扑结构基本一致,大部分舌鳎间的系统进化关系与传统形态分类的结论吻合,但长吻红舌鳎的分类地位表现出较大分歧,研究认为以侧线和鳞片数量这两个形态特征作为评估舌鳎系统进化的重要性需要重新评估。 相似文献
15.
鉴于联合国政府间气候变化专门委员会（IPCC）第五次评估报告（AR5）中第一工作组（WG I）的研究报告（IPCC-AR5-WG I）与科学研究的关联性更强、对科学研究的影响也最大，因此基于Web of Science引文数据库，通过科学计量法，利用描述性统计、空间分布分析以及网络分析等方法，分析IPCC-AR5-WG I的施引文献的时序、区域、机构合作以及主题领域等特征，以揭示其学术影响力及扩散情况。结果表明：IPCC-AR5-WG I在154个国家和地区的施引量呈逐年上升趋势，其中2021年出现爆发性增长；施引量最多的为美国、中国和英国，以美国、中国和欧洲的机构为代表形成了三大合作群，其中中国施引机构合作群的合作强度更高；施引文献广泛分布在182个学科领域中，呈现出多学科交叉影响的趋势；其包含扩散爆发期、突破发展期和交叉融合期等3个时期的学术影响力扩散主要分布在气候变化影响建模、温室气体排放与监测、气候变化对环境的影响以及遥感与极地气候变化四大领域，相关研究主题也呈现出由广泛到聚焦、由分散到融合的趋势。 相似文献
16.
V. M. Baikar M. V. Kamath C. Vishwanathan A. M. Varadkar S. E. Bharmal 《Indian journal of clinical biochemistry : IJCB》2003,18(1):80-86
TMAE-Fractogel 650 (M) (Trimethylaminoethyl) is an ion exchange medium can be used to capture factor VIII (F VIII) directly
from plasma. Previous reports have focused on the use of DEAE-Fractogel 650 (M) (Dimethylaminoethyl) ion exchange medium to
capture F VIII from cryoprecipitate and plasma. Our main objectives were (I) to standardise the purification of FVIII from
human plasma by column chromatographic technique. (II) to study the recovery of FVIII activity in purified fraction at 18–20°C
process condition. (III) to study the effect of virucidal step on recovery of FVIII activity and (IV) to study the effect
of lyophilisation on FVIII activity. In this report, Citrate Phosphate Dextrose (CPD) plasma was batch stirred with dry DEAE-Sephadex
A50, filtered, diluted, loaded on to a column packed with TMAE-Fractogel and chromatographed. Most of the unwanted proteins
flowed through the gel unadsorbed. Bound F VIII was eluted by increasing the ionic strength of the buffer. This purification
step gave an overall 80% recovery from the plasma with a specific activity of 0.97 IU FVIII/mg protein. The purified F VIII
fraction was made virus safe by employing the virucidal technique developed by New York Blood Centre (NYBC). There was 48.43%
loss of FVIII activity in Virus inactivation treatment and the loss of FVIII activity in lyophilisation was 8.45% which is
acceptable. This method of purification gave a higher yield of FVIII than cryoprecipitation, and is a promising alternative
method to cryoprecipitation of F VIII. 相似文献
17.
MPEG-2视频解码器检测码流,通常检测到的是语法错误,而由于可变长码的影响,检测到的错误位置并不是错误的起始位置。文章分析了MPEG-2码流的错误检测原理,介绍了能引起视频序列大范围出错的I-帧图像错误检测。 相似文献
18.
加强产学研融合和提出具有可行性的产学研联盟运行机制具有重要意义,笔者针对目前产学研联盟在运行过程中存在的诸多不协调的原因进行了分析,提出了多主体协调创新的产学研联盟运行机制,通过建立保障制度、人才软引进、健全工作机制和协调盈利模式等实现多方利益共赢,尤其是倡导利用商业化运营公司解决目前产学研联盟中的一些运行弊端来促进产学研联盟的健康发展。研究成果把运行机制具体化,并经过了实践的检验,便于落实和推广。 相似文献
19.
智能卡已经走进校园使学校的“数字校园”从概念变为现实,本文介绍了校园卡的分类、各种卡片的优缺点等,最后着重分析了校园卡的一种主流产品—MifareI型智能IC卡。 相似文献
20.
本文介绍了近年来在昆虫分类学领域研究热点之一的DNA条形码技术,综述了我国基于COI基因进行的昆虫分类学研究,并对COI基因对我国昆虫分类学的未来应用进行了展望。 相似文献