共查询到20条相似文献，搜索用时 31 毫秒
1.
Walter Schrott Zdeněk Slouka Petr ?ervenka Ji?í Ston Marek Nebyla Michal P?ibyl Dalimil ?nita 《Biomicrofluidics》2009,3(4)
Electrokinetic properties and morphology of PDMS microfluidic chips intended for bioassays are studied. The chips are fabricated by a casting method followed by polymerization bonding. Microchannels are coated with 1% solution of bovine serum albumin (BSA) in Tris buffer. Albumin passively adsorbs on the PDMS surface. Electrokinetic characteristics (electro-osmotic velocity, electro-osmotic mobility, and zeta potential) of the coated PDMS channels are experimentally determined as functions of the electric field strength and the characteristic electrolyte concentration. Atomic force microscopy (AFM) analysis of the surface reveals a “peak and ridge” structure of the protein layer and an imperfect substrate coating. On the basis of the AFM observation, several topologies of the BSA-PDMS surface are proposed. A nonslip mathematical model of the electro-osmotic flow is then numerically analyzed. It is found that the electrokinetic characteristics computed for a channel with the homogeneous distribution of a fixed electric charge do not fit the experimental data. Heterogeneous distribution of the fixed electric charge and the surface roughness is thus taken into account. When a flat PDMS surface with electric charge heterogeneities is considered, the numerical results are in very good agreement with our experimental data. An optimization analysis finally allowed the determination of the surface concentration of the electric charge and the degree of the PDMS surface coating. The obtained findings can be important for correct prediction and possibly for robust control of behavior of electrically driven PDMS microfluidic chips. The proposed method of the electro-osmotic flow analysis at surfaces with a heterogeneous distribution of the surface electric charge can also be exploited in the interpretation of experimental studies dealing with protein-solid phase interactions or substrate coatings. 相似文献
2.
Rui Xu 《Journal of The Franklin Institute》2013,350(10):3342-3364
In this paper, an eco-epidemiological predator–prey model with time delay representing the gestation period of the predator is investigated. In the model, it is assumed that the predator population suffers a transmissible disease by contact. By analyzing corresponding characteristic equations, the local stability of each of feasible equilibria and the existence of Hopf bifurcations at the disease-free equilibrium, the prey–infected predator equilibrium and the endemic-coexistence equilibrium are established. By means of Lyapunov functionals and LaSalle's invariance principle, sufficient conditions are obtained for the global asymptotic stability of the predator-extinction equilibrium, the disease-free equilibrium, the prey–infected predator equilibrium and the endemic-coexistence equilibrium of the model. 相似文献
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A predator–prey model with prey-dependent functional response is considered. The set of all points in the positive quadrant of the state plane that can be made equilibrium points by means of an affine state-feedback control law is determined, and the values of the control parameters ensuring the desired equilibria are provided. It is shown how the asymptotic stability of the equilibrium points depends on simple geometric conditions. The problem of stabilizing unstable equilibrium points is also briefly discussed. 相似文献
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《Journal of The Franklin Institute》2022,359(4):1427-1456
The energy regulation of fully actuated torque–driven robot manipulators in joint space is addressed in this paper. The proposed controller is designed via an energy shaping plus damping injection approach. The contribution is the proposal of an energy regulator with partial damping injection capable of inducing oscillations in the undamped joints of robot manipulators, with an user specified desired frequency and amplitude, by adding only damping in the rest of the joints, which may require less control effort than a trajectory tracking controller with full damping injection. Although viscous friction is considered in all joints of robot manipulator, it has been compensated via the proposed energy regulator. Moreover, the controlled periodic motion oscillates around a desired joint position as reference, and this provides a nice feature in the robot, mainly when there is not interest in the undamped joint to follow an specified time-varying sinusoidal function, but generating an oscillatory motion of constant amplitude and frequency. Instrumental in stability analysis is the Lyapunov’s theory and LaSalle’s theorem, which allows concluding that the closed-loop trajectories approach an invariant set that could include a unique equilibrium or periodic orbits. Numerical simulations on a manipulator arm model of two degrees of freedom illustrate the main results. 相似文献
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在均匀的交流电场作用下,应用布朗动力学模拟方法,研究了两端锚定的柔性和半柔性的单链聚电解质的动力学行为。研究结果表明,链段的位置随交流电场的变化表现出类似于磁滞回线的滞后效应,随着交流电的频率减小,这种滞后效应运渐消失,成为一条单一的曲线。本项目针对两端锚定的聚电解质随交流电场变化的动力学行为的研究,文献中未见报道。 相似文献
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Gas discharges generate oscillations superimposed on random noise of several megacycles bandwidth.Positive ions oscillate in two distinct regions of the discharge, i.e., the plasma and the potential minimum at the cathode.The disturbances produced by the ion motions appear as voltage variations between the electrodes.Oscillations generated in the plasma are usually below 400 kc./sec., while “cathode” oscillations are about 700 kc./sec.As the discharge current is increased, the amplitude of the plasma oscillation increases while its frequency decreases. The random noise also depends on current, increasing rapidly as the Townsend discharge changes into an are. After arc conditions are fully established, the noise changes slightly with current. Probe studies show that the noise voltage between probe and cathode increases rapidly as space charge conditions change to permit acceleration of electrons to the probe. When the probe collects positive ions, the noise as viewed on an oscilloscope is coarse, i.e., lacking in high frequency components.An explanation of the noise generation may be found in the random fluctuations of space charge at the electrodes. Calculations based on this theory give voltage fluctuations of the observed order of magnitude. 相似文献
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L. Luque-Vega B. Castillo-Toledo Alexander G. Loukianov 《Journal of The Franklin Institute》2012,349(2):719-739
This paper presents the design of a controller based on the block control technique combined with the super twisting control algorithm for trajectory tracking of a quadrotor helicopter. A first order exact differentiator is used in order to estimate the virtual control inputs, which simplifies the control law design. In addition, the wind parameter resulting from the aerodynamic forces is also estimated in order to ensure robustness against these unmatched perturbations. The stability and finite time convergence of the exact differentiator have been recently proved by means of Lyapunov functions, and therefore the stability analysis of the proposed controller has been carried out along the same lines. The performance and effectiveness of the proposed controller are tested in a simulation study taking into account external disturbances. 相似文献
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《Journal of The Franklin Institute》2022,359(10):4776-4803
Stability and energy consumption have always been important issues in electric vehicle research. Excessive slip energy not only aggravates tire wear, but also consumes energy of electric vehicle. In order to ensure the lateral stability and to reduce the slip energy dissipation of the distributed drive electric vehicle (DDEV) equipped with Mechanical Elastic Wheel (MEW), an integrated framework considering both tire slip energy dissipation and lateral stability control is proposed. The SESC (Slip Energy and Stability Control) is a hierarchical control framework for DDEV with MEW. A PID speed tracking controller and an (Integral Terminal Slide Mode) ITSM controller are designed at the upper-level controller. The ITSM controller can improve the lateral stability of the vehicle by obtaining the desired yaw moment. Speed tracking controller can stabilize the speed of the vehicle and obtain the desired longitudinal force. At the lower-level controller, the brush model of the MEW is proposed to express tire slip energy. In order to reduce the error of the vehicle dynamics and the slip energy dissipation, a mixed objective function including a holistic corner controller (HCC) and a minimum tire slip energy characterization is proposed. The proposed control framework is verified by Carsim and Matlab/Simulink under emergency simulation conditions. The simulation results show that the SESC based method can improve the lateral stability of DDEV with MEW effectively, and has better performance compared with fuzzyPID+AD based method. Meanwhile, the SESC achieves less slip energy than conventional torque distribution method. 相似文献
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Alternating-current (AC) electrokinetics involve the movement and behaviors of particles or cells. Many applications, including dielectrophoretic manipulations, are dependent upon charge interactions between the cell or particle and the surrounding medium. Medium concentrations are traditionally treated as spatially uniform in both theoretical models and experiments. Human red blood cells (RBCs) are observed to crenate, or shrink due to changing osmotic pressure, over 10 min experiments in non-uniform AC electric fields. Cell crenation magnitude is examined as functions of frequency from 250 kHz to 1 MHz and potential from 10 Vpp to 17.5 Vpp over a 100 μm perpendicular electrode gap. Experimental results show higher peak to peak potential and lower frequency lead to greater cell volume crenation up to a maximum volume loss of 20%. A series of experiments are conducted to elucidate the physical mechanisms behind the red blood cell crenation. Non-uniform and uniform electrode systems as well as high and low ion concentration experiments are compared and illustrate that AC electroporation, system temperature, rapid temperature changes, medium pH, electrode reactions, and convection do not account for the crenation behaviors observed. AC electroosmotic was found to be negligible at these conditions and AC electrothermal fluid flows were found to reduce RBC crenation behaviors. These cell deformations were attributed to medium hypertonicity induced by ion concentration gradients in the spatially nonuniform AC electric fields. 相似文献
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针对由供应商和制造商构成的两级供应链系统,在不完全信息条件下,建立以服务水平作为传递信号的供应链动态博弈模型,分析供应链信号博弈中分离均衡的实现过程及存在条件,最终给出分离均衡下供应链质量管理的有效对策。研究表明,制造商能够根据获取的服务质量信号,对供应商的潜在行为进行分析,选择最佳的应对策略,降低自身的运营风险,增强供应链合作的稳定性。 相似文献
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John Zeleny 《Journal of The Franklin Institute》1932,214(5):513-532
A criticism by Loeb and Bradbury of my interpretation of the experimental results of that part of a previous paper which dealt with the aging of negative ions in commercial nitrogen is shown to be invalidated by a mistake in their analysis and by assumptions which do not represent facts with sufficient accuracy. A more extended analysis of the previous work and new evidence which is given confirm the correctness of the former contention that the negative ions in question changed in size with age. The lateral spread, owing to diffusion, of a stream of electrons in this nitrogen at atmospheric pressure, when moving in an electric field of about 100 volts/cm., was found to be very nearly the same as that for positive ions under like conditions. The average energy losses of the electrons at collision with the molecules must therefore have nearly balanced the gains from the electric field and hence were greater than would result from purely elastic collisions. The experimental results indicate that in fields down to at least 20 volts/cm. nearly all of the attachment of electrons to molecules in the gas used occurred close to the place of their liberation. 相似文献
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《Journal of The Franklin Institute》2022,359(17):9971-9988
The stability issue of discrete-time switched systems governed by cyclic switching laws is discussed in this paper. By establishing inverse-timer-based multiple Lyapunov functions (ITBMLFs), which are less conservative than traditional MLFs, limitations of the existing findings on discrete-time cyclic switched systems (DTCSSs) are well relaxed. Furthermore, from the perspective of computational complexity adjustment, the proposed ITBMLFs are confirmed to be more flexible than the previous ones, which is especially meaningful for the DTCSSs consisting of a large number of subsystems. Based on the cycle-dependent average dwell time (CD-ADT) concept and the ITBMLF approach, newly enhanced stability conditions are launched for DTCSSs where subsystems can be entirely or partially stable, or even completely unstable. Moreover, robust stability of DTCSSs can be achieved when norm-bounded and time-varying parameter uncertainties (NBTVPUs) are taken into account. Finally, the effectiveness and superiority of the proposed technologies are expounded through numerical examples. 相似文献
14.
Mont Hubbard 《Journal of The Franklin Institute》1979,308(4):405-421
Bond graphs are used to generate the equations of motion of a whirling flywheel. The formulation is shown to be a natural one when control forces and moments are included for active control of the whirling modes. Critical frequencies are interpreted as rotational speeds at which non-zero equilibrium configurations exist for displacements (as opposed to the more familiar momenta) and arise when the system dynamics matrix of the complete whirl motion has two zero eigenvalues. In addition, oscillatory modes corresponding to non-zero eigenvalues are examined. Time simulations and other numerical results are given for an example flywheel system which has been proposed for electric utility energy storage. 相似文献
15.
A novel actuation method of transporting droplets by using electrical charging of droplet in a dielectric fluid 总被引：1，自引：0，他引：1
We evaluate the feasibility of manipulating droplets in two dimensions by exploiting Coulombic forces acting on conductive droplets immersed in a dielectric fluid. When a droplet suspended in an immiscible fluid is located near an electrode under a dc voltage, the droplet can be charged by direct contact, by charge transfer along an electrically conducting path, or by both mechanisms. This process is called electrical charging of droplet (ECOD). This charged droplet may then be transported rapidly by exploiting Coulombic forces. We experimentally demonstrate electrical actuation of a charged droplet by applying voltage sequences. A charged droplet is two dimensionally actuated by following the direction of the electrical field signal. The droplet does not contact the surface of the microfluidic chip when it moves. This characteristic is very advantageous because treatments of the substrate surfaces of microfluidic chip become simpler. In order to test the feasibility of using ECOD in a droplet-based microreactor, electrocoalescence of two oppositely charged droplets is also studied. When two droplets approach each other due to Coulombic attraction, a liquid bridge is formed between them. We postulate that if the applied electric field is weaker than a certain critical level, the two droplets coalesce instantaneously when the charges are exchanged and redistributed through this liquid bridge. 相似文献
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Shih-Hsiang Chang 《Biomicrofluidics》2009,3(1)
A theoretical study on the transient electro-osmotic flow through a cylindrical microcapillary containing a salt-free medium is presented for both constant surface charge density and constant surface potential. The exact analytical solutions for the electric potential distribution and the transient electro-osmotic flow velocity are derived by solving the nonlinear Poisson-Boltzmann equation and the Navier-Stokes equation. Based on these results, a systematic parametric study on the characteristics of the transient electro-osmotic flow is detailed. The general behavior of transient electro-osmotic flow in a cylindrical tube is similar to that observed in a microchannel containing an electrolyte solution. However, the steady-state electro-osmotic flow significantly deviates from the typical plug flow at higher surface charge and the rate of increase in the electro-osmotic mobility is strongly suppressed due to the effect of counterion condensation. In addition, the applicability limit of these solutions is also discussed. 相似文献
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This paper investigates the chaos control problem of a new multi-scroll chaotic system. Two nonlinear control methods are studied, namely high-order and predictive types of control. The proposed methodologies offer the possibility of stabilizing unstable periodic orbits and unstable equilibrium points from the state equations. For this purpose, we apply the high-order control method for stabilizing a desired unstable periodic orbit, while the predictive control method is applied for stabilization problem of unstable equilibrium points. In particular, these approaches are effective and easy to be implemented since we only need to apply small perturbations to the system dynamics. The multi-scroll Chen system is used as representative example to show the working principle of these methods. Numerical simulation results indicate the potential engineering applications of the proposed control methods for various multi-scroll chaos-based practical applications. 相似文献
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We studied the mobility of DNA molecules driven by an electric field through a nanofluidic device containing a periodic array of deep and shallow regions termed entropic traps. The mobility of a group of DNA molecules was measured by fluorescent video microscopy. Since the depth of a shallow region is smaller than the DNA equilibrium size, DNA molecules are trapped for a characteristic time and must compress themselves to traverse the boundary between deep and shallow regions. Consistent with previous experimental results, we observed a nonlinear relationship between the mobility and electric field strength, and that longer DNA molecules have larger mobility. In repeated measurements under seemingly identical conditions, we measured fluctuations in the mobility significantly larger than expected from statistical variation. The variation was more pronounced for lower electric field strengths where the trapping time is considerable relative to the drift time. To determine the origin of these fluctuations, we investigated the dependence of the mobility on several variables: DNA concentration, ionic strength of the solvent, fluorescent dye staining ratio, electroosmotic flow, and electric field strength. The mobility fluctuations were moderately enhanced in conditions of reduced ionic strength and electroosmotic flow. 相似文献
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采用博弈方法,在构造产学研合作博弈收益表的基础上让不同产学研合作组织选择某种交流方式作为策略,并以收益函数为效用函数对产学研合作组织的不同互动合作网络和不同人员采取不同交流方式的协调进行均衡分析。研究发现:对于任意一个产学研合作互动网络,采取相同交流的策略组合是在纳什均衡的条件下,如果网络是完整的,那么这些是可能仅有的纳什均衡;如果网络不完整,那么可能存在交流方式多样化的均衡。而在每个网络内部参与者采取不同交流的策略组合都是在纳什均衡条件下,无论网络是完整还是不完整的,都可能存在交流方式多样化的均衡。接着分析产学研合作初期阶段中,不同人员交流方式的囚徒困境均衡具有历史路径依赖性,并且难以通过内部协调交流方式走出困境,但是可以通过产学研合作组织中不同人员交流方式的协调达到帕累托均衡。 相似文献