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1.
Abstract

The aim of this study was to determine the variations in substrate utilization between men and women matched for ventilatory threshold (T vent) during incremental arm cranking and leg cycling exercise at 70, 85, 100 and 115% of the mode-specific T vent. Recreationally active men (n = 12) and women (n = 10) with similar values for percentage of peak oxygen consumption at T vent participated in the study. Ventilatory equivalence, excess CO2 and modified V-slope methods were used concurrently to determine T vent. The participants performed 5 min of exercise at each of 70, 85, 100 and 115% T vent during both arm cranking and leg cycling exercise. The females were tested during the early follicular phase for all trials. A two-way mixed-design analysis of variance was performed to test for differences between the sexes. When carbohydrate and fat oxidation were expressed relative to total fat-free mass, carbohydrate oxidation during arm cranking and leg cycling was significantly higher in men than women at each percentage of T vent. In contrast, women showed significantly higher fat oxidation across intensities during both arm cranking and leg cycling. Our results suggest that when substrate utilization is expressed relative to total fat-free mass, women appear to maintain a higher rate of fat and lower rate of carbohydrate oxidation than men during both incremental arm cranking and leg cycling exercise relative to T vent.  相似文献   

2.
This study examined the effects of prior exercise on the lactate (Tlac) and ventilatory (Tvent) thresholds. Ten healthy male subjects volunteered to perform one-legged cycling. Muscle glycogen reduction was achieved by cycling at 75-85% of maximal heart rate for 60-75 min, and by a low carbohydrate diet. Pre- and post-exercise tests for measuring the thresholds employed a 3-min continuous protocol in 16 W increments. Muscle biopsies (n = 3) were taken from the vastus lateralis before the 'prior exercise' (PE) ride, the post-PE threshold test, and before testing the non-exercised (NE) leg. An i.v. catheter was used for serial blood lactate concentration determination during rest and the final 30 s of each progressive load. Ventilatory gas analyses were performed every 30 s. Biopsies showed that the PE and diet regimen reduced muscle glycogen in the PE leg (46.7%) and NE leg (36.4%). Venous blood lactate and respiratory exchange ratio (R) were reduced at Tlac and Tvent in both the PE and NE leg. The VO2 at a blood lactate concentration of 4 mmol l-1 was elevated in the PE leg at Tlac (2.89 versus 2.46 1 min-1), but not in the NE leg at Tlac. These results suggest that lactate concentration at Tlac and Tvent is reduced by endurance exercise performed 24 h prior to testing, and that the central circulation plays a major role in this response. Furthermore, since blood lactate is reduced at the thresholds by prior exercise, the use of a lactate level of 4 mmol l-1 as a criterion for Tlac should be interpreted cautiously.  相似文献   

3.
Carbohydrate ingestion before and during endurance exercise delays the onset of fatigue (reduced power output). Therefore, endurance athletes are recommended to ingest diets high in carbohydrate (70% of total energy) during competition and training. However, increasing the availability of plasma free fatty acids has been shown to slow the rate of muscle and liver glycogen depletion by promoting the utilization of fat. Ingested fat, in the form of long-chain (C 16-22 ) triacylglycerols, is largely unavailable during acute exercise, but medium-chain (C 8-10 ) triacylglycerols are rapidly absorbed and oxidized. We have shown that the ingestion of medium-chain triacylglycerols in combination with carbohydrate spares muscle carbohydrate stores during 2 h of submaximal (< 70% VO 2 peak) cycling exercise, and improves 40 km time-trial performance. These data suggest that by combining carbohydrate and medium-chain triacylglycerols as a pre-exercise supplement and as a nutritional supplement during exercise, fat oxidation will be enhanced, and endogenous carbohydrate will be spared. We have also examined the chronic metabolic adaptations and effects on substrate utilization and endurance performance when athletes ingest a diet that is high in fat (> 70% by energy). Dietary fat adaptation for a period of at least 2-4 weeks has resulted in a nearly two-fold increase in resistance to fatigue during prolonged, low- to moderate-intensity cycling (< 70% VO 2 peak). Moreover, preliminary studies suggest that mean cycling 20 km time-trial performance following prolonged submaximal exercise is enhanced by 80 s after dietary fat adaptation and 3 days of carbohydrate loading. Thus the relative contribution of fuel substrate to prolonged endurance activity may be modified by training, pre-exercise feeding, habitual diet, or by artificially altering the hormonal milieu or the availability of circulating fuels. The time course and dose-response of these effects on maximizing the oxidative contribution of fat for exercise metabolism and in exercise performance have not been systematically studied during moderate- to high-intensity exercise in humans.  相似文献   

4.
Abstract

In this study we determined the exercise intensity that elicits the highest fat oxidation rate in 15 obese women and 13 obese men. Furthermore the relationship between this intensity with the lactate (LT) and ventilatory thresholds (VT) was investigated in order to give training recommendation for maximal fat utilization during endurance exercise. After an incremental exercise test until exhaustion on a cycle ergometer, subjects performed six 20-min exercise bouts of 25, 35, 45, 55, 65 and 75% VO2peak. The 20 min stages were randomly assigned and spread over two separate occasions (three bouts per occasion). Substrate oxidation was measured with indirect calorimetry and was calculated using stochiometric equations. In both, women and men the highest fat oxidation rate occurred at 65% VO2peak and this did not coincide with either the VT or LT. A significant correlation between VT and LT could not be found in women (r=0.33) nor men (r=0.277). In obese women and men training recommendation for maximal fat utilization should not only be given by the intensity at which AnT occurs.  相似文献   

5.
本文研究了单侧手摇或脚踩功率自行车运动时心率(HR)的不同反应。结果发现,在较低负荷时(25W),两种运动方式下的HR几无差别(P>.05);但随着负荷的增加(50W和75W时),手摇运动时心率上升得更高,和脚踩相比有明显的差异性(P<0.05和p<0.001)。以上结果表明,参与运动的肌肉群数量和大小不同,引起的心血管反应也有所差别,其机制可能和交感紧张性升高及更高的通气率等因素有关。  相似文献   

6.
In this study, we wished to determine whether the changes in metabolism observed during exercise in the cold are associated with changes in interleukin-6 (IL-6) and/or its soluble receptors. Eight healthy male participants performed 1 h of cycling exercise at 70% VO2max in a control (20 degrees C) and cold (0 degrees C) environment. Plasma concentrations of IL-6, soluble IL-6 receptor (sIL-6R), and sgp130 were measured before exercise, at 30 and 60 min of exercise, and 60 min after exercise. Substrate oxidation was estimated through measures of pulmonary gas exchange recorded between 50 and 55 min of cycling. Exercise in the cold resulted in an increase (P < 0.05) in carbohydrate oxidation (mean 2.58 g.min(-1), s = 0.49 at 20 degrees C vs. 2.85 g.min(-1), s = 0.58 at 0 degrees C) and a decrease (P < 0.05) in fat oxidation (0.55 g.min(-1), s = 0.17 at 20 degrees C vs. 0.38 g.min(-1), s = 0.16 at 0 degrees C) compared with the control trial. Interleukin-6 concentrations were elevated (P < 0.05) after 60 min of exercise in both the cold and control trials, with no differences between trials at any instant. Neither sIL-6R nor sgp130 was affected by exercise or the environment. The alterations in carbohydrate and fat utilization during 1 h of exercise in the cold are not paralleled by changes in plasma concentrations of IL-6 or its soluble receptors.  相似文献   

7.
Abstract

The increased energy demand that occurs with incremental exercise intensity is met by increases in the oxidation of both endogenous fat and carbohydrate stores up to an intensity of ~70% V˙O2max in trained individuals. However, when exercise intensity increases beyond this workload, fat oxidation rates decline, both from a relative and absolute perspective. As endogenous glycogen use is accelerated, glycogen stores can become depleted, ultimately resulting in fatigue and the inability to maintain high intensity, submaximal exercise (>70% V˙O2max). Despite a considerable accumulation of knowledge that has been gained over the past half century, the precise mechanism(s) regulating muscle fuel selection and underpinning the aforementioned decline in fat oxidation remain largely unclear. A greater understanding would undoubtedly lead to novel strategies to increase fat utilization and, as such, improve exercise capacity. The present review primarily addresses one of the most prominent theories to explain the phenomenon of diminished fat oxidation during high intensity, submaximal exercise; a reduced availability of muscle free carnitine for mitochondrial fat translocation. This is discussed in the light of recent work in this area taking advantage of the discovery that muscle carnitine content can be increased in vivo in humans. Furthermore, the evidence supporting the recently proposed theory that reduced muscle co-enzyme A availability to several key enzymes in the fat oxidation pathway may also exert a degree of control over muscle fuel selection during exercise is also considered. Strong correlational evidence exists that muscle free carnitine availability is likely to be a key limiting factor to fat oxidation during high intensity, submaximal exercise. However, it is concluded that further intervention studies manipulating the muscle carnitine pool in humans are required to establish a direct causal role. In addition, it is concluded that while a depletion of muscle coenzyme A availability during exercise also offers a viable mechanism for impairing fat oxidation, at present, this remains speculative.  相似文献   

8.
Abstract

The bradycardia effect of a 10-week jogging program was studied in 13 previously sedentary middle-aged subjects (seven women and six men). This response during standardized submaximal treadmill walking and leg cycling was related to changes in cardiac output ([Qdot]), stroke volume (SV), and arteriovenous oxygen differences (a-vO2 diff). Heart rate (HR) response was also studied during load carrying and arm cycling tasks, and a [Vdot]O2 max test was administered. All tests were repeated posttraining. The posttraining increases in [Vdot]O2 max (ml/kg × min-1) were 19.7% and 14.8% for the men and women respectively. Training also produced significant reductions in submaximal HR and Q during treadmill and leg cycling exercise. A-vO2 diff rose, while there were no changes in [Vdot]O2 during the submaximal work tasks, suggesting either altered blood flow or a greater capacity to utilize O2 by the working muscle. Both men and women showed significant reductions in HR during the arm cycling and load carrying as well. These data suggest that a jogging program can alter cardiovascular function in tasks other than running. The magnitude and direction of change showed no sex differences; therefore, it was also concluded that there are no differences in the trainability of previously sedentary middle-aged men and women.  相似文献   

9.
The purpose of this investigation was to determine the effect of a combined strength and aerobic conditioning program on the ability of college-age women to perform the pull-up exercise and to identify the characteristics of women successful in performing a pull-up at the end of the program. Participants significantly increased upper body strength and fat-free mass and deceased fat mass and percentage of body fat. Participants successful at performing a pull-up had significantly greater 1 repetition maximum strength, strength to mass ratio, and strength to fat-free mass ratio. A two variable equation (% body fat and strength to fat-free mass ratio) was developed to predict which women would be successful at completing a pull-up at the end of a similar training program.  相似文献   

10.
A key goal of pre-exercise nutritional strategies is to maximize carbohydrate stores, thereby minimizing the ergolytic effects of carbohydrate depletion. Increased dietary carbohydrate intake in the days before competition increases muscle glycogen levels and enhances exercise performance in endurance events lasting 90 min or more. Ingestion of carbohydrate 3-4 h before exercise increases liver and muscle glycogen and enhances subsequent endurance exercise performance. The effects of carbohydrate ingestion on blood glucose and free fatty acid concentrations and carbohydrate oxidation during exercise persist for at least 6 h. Although an increase in plasma insulin following carbohydrate ingestion in the hour before exercise inhibits lipolysis and liver glucose output, and can lead to transient hypoglycaemia during subsequent exercise in susceptible individuals, there is no convincing evidence that this is always associated with impaired exercise performance. However, individual experience should inform individual practice. Interventions to increase fat availability before exercise have been shown to reduce carbohydrate utilization during exercise, but do not appear to have ergogenic benefits.  相似文献   

11.
The aim of this study was to determine the relationship between force and velocity parameters during a specific multi-articular upper limb movement--namely, hand rim propulsion on a wheelchair ergometer. Seventeen healthy able-bodied females performed nine maximal sprints of 8 s duration with friction torques varying from 0 to 4 N x m. The wheelchair ergometer system allows measurement of forces exerted on the wheels and linear velocity of the wheel at 100 Hz. These data were averaged for the duration of each arm cycle. Peak force and the corresponding maximal velocity were determined during three consecutive arm cycles for each sprint condition. Individual force-velocity relationships were established for peak force and velocity using data for the nine sprints. In line with the results of previous studies on leg cycling or arm cranking, the force-velocity relationship was linear in all participants (r = -0.798 to -0.983, P < 0.01). The maximal power output (mean 1.28 W x kg(-1)) and the corresponding optimal velocity (1.49 m x s(-1)) and optimal force (52.3 N) calculated from the individual force-velocity regression were comparable with values reported in the literature during 20 or 30 s wheelchair sprints, but lower than those obtained during maximal arm cranking. A positive linear relationship (r = 0.678, P < 0.01) was found between maximal power and optimal velocity. Our findings suggest that although absolute values of force, velocity and power depend on the type of movement, the force-velocity relationship obtained in multi-articular limb action is similar to that obtained in wheelchair locomotion, cycling and arm cranking.  相似文献   

12.
耐力运动中要保持较高的输出功率必须同时利用糖和脂肪供能。事实上。机体内存在着复杂的机制调节糖和脂肪的利用。试从激素的调节、葡萄糖-脂肪酸循环及丙二酰CoA的调节三个方面来综述耐力运动中糖和脂肪利用的研究进展。  相似文献   

13.
This study examined the effects of caffeine, co-ingested with a high fat meal, on perceptual and metabolic responses during incremental (Experiment 1) and endurance (Experiment 2) exercise performance. Trained participants performed three constant-load cycling tests at approximately 73% of maximal oxygen uptake (VO2max) for 30 min at 20 degrees C (Experiment 1, n = 8) and to the limit of tolerance at 10 degrees C (Experiment 2, n = 10). The 30 min constant-load exercise in Experiment 1 was followed by incremental exercise (15 W . min-1) to fatigue. Four hours before the first test, the participants consumed a 90% carbohydrate meal (control trial); in the remaining two tests, the participants consumed a 90% fat meal with (fat + caffeine trial) and without (fat-only trial) caffeine. Caffeine and placebo were randomly assigned and ingested 1 h before exercise. In both experiments, ratings of perceived leg exertion were significantly lower during the fat + caffeine than fat-only trial (Experiment 1: P < 0.001; Experiment 2: P < 0.01). Ratings of perceived breathlessness were significantly lower in Experiment 1 (P < 0.01) and heart rate higher in Experiment 2 (P < 0.001) on the fat + caffeine than fat-only trial. In the two experiments, oxygen uptake, ventilation, blood [glucose], [lactate] and plasma [glycerol] were significantly higher on the fat + caffeine than fat-only trial. In Experiment 2, plasma [free fatty acids], blood [pyruvate] and the [lactate]:[pyruvate] ratio were significantly higher on the fat + caffeine than fat-only trial. Time to exhaustion during incremental exercise (Experiment 1: control: 4.9, s = 1.8 min; fat-only: 5.0, s = 2.2 min; fat + caffeine: 5.0, s = 2.2 min; P > 0.05) and constant-load exercise (Experiment 2: control: 116 (88 - 145) min; fat-only: 122 (96 - 144) min; fat + caffeine: 127 (107 - 176) min; P > 0.05) was not different between the fat-only and fat + caffeine trials. In conclusion, while a number of metabolic responses were increased during exercise after caffeine ingestion, perception of effort was reduced and this may be attributed to the direct stimulatory effect of caffeine on the central nervous system. However, this caffeine-induced reduction in effort perception did not improve exercise performance.  相似文献   

14.
We examined the effects of concomitant increases in crank rate and power output on incremental arm crank ergometry. Ten healthy males undertook three incremental upper body exercise tests to volitional exhaustion. The first test determined peak minute power. The subsequent tests involved arm cranking at an initial workload of 40% peak minute power with further increases of 10% peak minute power every 2 min. One involved a constant crank rate of 70 rev · min(-1), the other an initial crank rate of 50 rev · min(-1) increasing by 10 rev · min(-1) every 2 min. Fingertip capillary blood samples were analysed for blood lactate at rest and exhaustion. Local (working muscles) and cardiorespiratory ratings of perceived exertion (RPE) were recorded at the end of each exercise stage. Heart rate and expired gas were monitored continuously. No differences were observed in peak physiological responses or peak minute power achieved during either protocol. Blood lactate concentration tended to be greater for the constant crank rate protocol (P = 0.06). Test duration was shorter for the increasing than for the constant crank rate protocol. The relationship between local RPE and heart rate differed between tests. The results of this study show that increasing cadence during incremental arm crank ergometry provides a valid assessment of peak responses over a shorter duration but alters the heart rate-local RPE relationship.  相似文献   

15.
Abstract

The aim of this study was to determine whether rates of total fat and carbohydrate oxidation and endurance capacity during running conducted in the fasted state are influenced by the glycaemic index (GI) of high carbohydrate diets consumed over 5 days. Nine healthy males performed three treadmill runs to exhaustion at 65% of maximum oxygen uptake ([Vdot]O2max): after a habitual diet (control trial), after 5 days on a high carbohydrate/high glycaemic index diet, and after 5 days on a high carbohydrate/low glycaemic index diet in randomized counterbalanced order. No significant differences in rates of fat and carbohydrate oxidation, concentrations of plasma insulin, glucose, non-esterified fatty acids and glycerol, or time to exhaustion were observed between the high carbohydrate/high glycaemic index and high carbohydrate/low glycaemic index trials. Compared with the control trial, the concentration of plasma glycerol and rate of fat oxidation were lower (P < 0.05) and the rate of carbohydrate oxidation higher (P < 0.05) in both the high carbohydrate/high glycaemic index diet and high carbohydrate/low glycaemic index trials during the run to exhaustion. In conclusion, the extent by which a high carbohydrate diet consumed over 5 days reduces rate of fat oxidation during subsequent running exercise in the fasted state is not influenced by the glycaemic index of the diet.  相似文献   

16.
Kinetics of heart rate responses to exercise   总被引:4,自引:0,他引:4  
In order to describe the kinetics of the reaction of the heart rate (HR) to the onset of exercise of constant intensity, the half-time (t1/2) of HR can be used. First in a study of exercise of intensity corresponding to 2 W kg-1 on a cycle ergometer, the t1/2 in 15 trained male rowers and 11 untrained male students was determined. In the trained subjects t1/2 was smaller than in untrained students, mean (+/- S.D.) values being 24.10 (+/- 3.36) s and 47.12 (+/- 4.08) s respectively. In both groups t1/2 was positively correlated with resting HR, r = 0.774 and 0.846 and negatively correlated with maximal oxygen uptake (VO2max), r = -0.728 and -0.871 respectively (P less than 0.01). The regulation of HR in the transition range was concluded to be very similar to the regulation of VO2 and energy requirements. The second part of this work was concerned with responses to graded exercise. The linearity of the HR-exercise intensity relationship is maintained up to a submaximal exercise intensity beyond which the increase in exercise intensity exceeds the increase in HR. It was hypothesized that the point where HR departs from linearity in an incremental exercise test may be employed as a predictor of the ventilatory threshold (Tvent). To examine this, 28 trained male long-distance runners were tested on a treadmill and 17 untrained young male subjects were tested on a cycle ergometer using a continuous incremental protocol. The Tvent was determined from the dependence of VE on VO2 and/or VCO2. The VO2, HR and exercise intensity at Tvent were compared with the same parameters determined from the dependence of HR on exercise intensity. No significant differences were found between Tvent and HR break point levels. It was concluded from this second study that the HR break point level coincides with Tvent.  相似文献   

17.
Following preliminary indications that in some individuals arm exercise enhanced rather than reduced simultaneous leg endurance, ten young men and women performed three forms of intermittent work to volitional exhaustion, under duty cycles of 45 s work, 15 s rest. The protocols were as follows: (A) knee extensions at 30% maximum voluntary contraction (MVC); (B) 30% MVC knee extensions combined with arm cranking at 130% of their own lactate threshold; (C) combined 30% MVC knee extensions and arm cranking at 20% of their own lactate threshold. Heart rate, oxygen uptake (VO(2)), and blood lactate concentration were among the variables recorded throughout. All physiological indicators of demand were substantially higher in protocol B than in protocols A or C [heart rate: (A) 154 beats . min(-1), (B) 171 beats . min(-1), (C) 150 beats . min(-1); VO(2): (A) 11.9 ml . kg(-1) . min(-1), (B) 21.7 ml . kg(-1) . min(-1), (C) 14.2 ml . kg(-1) . min(-1); blood lactate concentration: (A) 3.3 mmol . l(-1), (B) 5.1 mmol . l(-1), (C) 2.8 mmol . l(-1)], yet there were no significant differences (P > 0.05) in the endurance times between the three conditions [(A) 11.43 min, (B) 11.1 min, (C) 10.57 min] and seven participants endured longest in protocol B. Results from protocol (C) cast doubt on explanations in terms of psychological distraction. We suggest that lactic acid produced by the arms is shuttled to the legs and acts there either as a supplementary fuel source or as an antagonist to the depressing effects of increased potassium concentration.  相似文献   

18.
The aim of the present study was to examine the effect of ingesting 75 g of glucose 45 min before the start of a graded exercise test to exhaustion on the determination of the intensity that elicits maximal fat oxidation (Fatmax). Eleven moderately trained individuals (VO2max: 58.9 +/- 1.0 ml x kg(-1) x min(-1); mean +/- sx), who had fasted overnight, performed two graded exercise tests to exhaustion, one 45 min after ingesting a placebo drink and one 45 min after ingesting 75 g of carbohydrate in the form of glucose. The tests started at 95 W and the workload was increased by 35 W every 3 min. Gas exchange measures and heart rate were recorded throughout exercise. Fat oxidation rates were calculated using stoichiometric equations. Blood samples were collected at rest and at the end of each stage of the test. Maximal fat oxidation rates decreased from 0.46 +/- 0.06 to 0.33 +/- 0.06 g min(-1) when carbohydrate was ingested before the start of exercise (P < 0.01). There was also a decrease in the intensity which elicited maximal fat oxidation (60.1 +/- 1.9% vs 52.0+3.4% VO2max) after carbohydrate ingestion (P < 0.05). Maximal power output was higher in the carbohydrate than in the placebo trial (346 +/- 12 vs 332 +/- 12 W) (P < 0.05). In conclusion, the ingestion of 75 g of carbohydrate 45 min before the onset of exercise decreased Fatmax by 14%, while the maximal rate of fat oxidation decreased by 28%.  相似文献   

19.
The aim of this study was to determine the relationship between force and velocity parameters during a specific multi-articular upper limb movement – namely, hand rim propulsion on a wheelchair ergometer. Seventeen healthy able-bodied females performed nine maximal sprints of 8?s duration with friction torques varying from 0 to 4?N?·?m. The wheelchair ergometer system allows measurement of forces exerted on the wheels and linear velocity of the wheel at 100 Hz. These data were averaged for the duration of each arm cycle. Peak force and the corresponding maximal velocity were determined during three consecutive arm cycles for each sprint condition. Individual force–velocity relationships were established for peak force and velocity using data for the nine sprints. In line with the results of previous studies on leg cycling or arm cranking, the force–velocity relationship was linear in all participants (r?=??0.798 to ?0.983, P?<0.01). The maximal power output (mean 1.28?W?·?kg?1) and the corresponding optimal velocity (1.49?m?·?s?1) and optimal force (52.3?N) calculated from the individual force–velocity regression were comparable with values reported in the literature during 20 or 30?s wheelchair sprints, but lower than those obtained during maximal arm cranking. A positive linear relationship (r?=?0.678, P?<0.01) was found between maximal power and optimal velocity. Our findings suggest that although absolute values of force, velocity and power depend on the type of movement, the force–velocity relationship obtained in multi-articular limb action is similar to that obtained in wheelchair locomotion, cycling and arm cranking.  相似文献   

20.
This study examined the effect of shoulder angle and gender on physiological and perceptual responses during incremental peak arm ergometry. Healthy adults (nine males, seven females) volunteered for the study and completed an incremental arm ergometry test on two separate occasions at two different shoulder angles (90 degrees and 45 degrees). Initial work rate was set at 16 W x min-1 and was increased progressively until exhaustion. Cardiorespiratory and perceptual responses were recorded at the end of each minute and compared using separate three-way (position x work rate x gender) repeated-measures analyses of variance. The systematic bias of peak responses was examined using separate two-way (position x gender) analyses of variance, while reproducibility of these parameters was explored using intraclass correlation coefficients, measurement bias/ratio, and 95% ratio limits of agreement. Despite a significantly greater peak heart rate for the 45 degrees position, cardiorespiratory and perceptual responses were similar at peak exercise for both positions. Peak values for all variables, although similar, demonstrated similar and large inter-test variability for men and women. Reduction of the shoulder joint angle to 45 degrees did not enhance peak work rate and peak oxygen consumption during seated upper body exercise. Due to the large inter-test variability, arm ergometry should be conducted using the same seated position.  相似文献   

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