共查询到20条相似文献，搜索用时 62 毫秒
1.
氯氰碘柳胺脂质体的研制和驱虫效果试验 总被引：3，自引：0，他引：3
采用改良的冷冻融溶法制备氯氰碘柳胺脂质体，经线性试验、方法回收率、包封率测定和稳定性试验，该制剂符合质量标准。临床药物试验表明以2．5mg/kg的剂量皮下注射，对绵羊的肝片吸虫有完全的驱除作用，最佳使用剂量。该制剂用药量小，疗效高，毒副作用低，是一种值得推广的抗寄生虫药物。 相似文献
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缓释制剂是第三代药物制剂,这种制剂由于克服了频繁给药的弊端,有利于降低药物的不良反应,能在较长时间内维持体内药物有效浓度,可减少用药的总剂量,用最小剂量达到最大药效,从而可大大提高患者服药的顺应性,被广泛用于治疗多种疾病。本文从制备缓释制剂所用辅料、缓释制剂的剂型等方面的研究进展作了综述. 相似文献
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介绍了阿昔洛韦（AC）胶囊剂的研制以及该制剂的溶出度试验方法，指出通过处方筛选，选择适当浓度的表面活性剂、润滑剂及其它辅料，可增加药物的溶出，提高生物利用度。 相似文献
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采用高效液相色谱法,以布洛芬为内标,对24 h酮洛芬骨架缓释片试验制剂以24名健康志愿者进行多剂量人体相对生物利用度试验.结果表明,试验制剂具有明显的缓释药动学特征,参比制剂的Cmax显著高于试验制剂（p〈0.01）,试验制剂给药后的tmax延迟,且吸收程度与作为标准参比制剂的市售缓释片相比无显著差异,人体相对生物利用度为103.76%.经统计学检验表明这两种制剂具有生物等效性,试验制剂具有峰谷浓度差异小、波动幅度小的特点,显示出缓释特征. 相似文献
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本文通过药物对比试验，发现微生态制剂对蛋鸡腹泻疗效显著，并对此进行分析，肯定了其推广价值。 相似文献
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细菌药物敏感试验的结果是临床合理用药的重要依据。从药敏试验方法选择错误、药敏试验操作不规范、药敏纸片质量的影响、病原菌鉴定不明确、细菌药敏结果敏感但临床治疗耐药、药敏试验的药物剂量与临床用药剂量有较大差异等6个方面,分析造成细菌药敏结果与临床疗效不符的原因,为临床有效治疗感染性疾病提供参考。 相似文献
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目的:综合评价复方西洋参和红枣制剂对于小鼠非特异性免疫和特异性免疫的影响,为开发新产品奠定基础。创新点:本文首次以西洋参提取物和红枣提取物为原料制成复方制剂,并通过动物实验发现该制剂具有增强免疫功能,为开发功能性食品提供新思路。方法:将西洋参与红枣提取物按一定比例制备复方制剂,以1.3、2.6和5.2 g/kg为低、中和高剂量给健康ICR小鼠连续灌胃此复方制剂4周,对照组灌胃同等剂量的无菌水,最后通过测定免疫相关指标对该复方制剂的免疫调节功能进行综合评价。结论:此款复方制剂可以显著提高小鼠的胸腺和脾脏指数(表1),同时低剂量组小鼠的血清溶血素水平显著高于对照组,高剂量组小鼠的脾淋巴细胞增值能力约是对照组的2.4倍,自然杀伤细胞的活性也得到显著增强,中剂量组小鼠的NK细胞活性与对照组相比提高了78.6%(图2)。另外,此复方制剂能有效提高小鼠组织(肝脏、脾脏和胸腺)和血清中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、过氧化氢酶(CAT)的活性,同时降低丙二醛(MDA)的含量(图3~6)。综上所述,此复方西洋参和红枣制剂可有效提高健康ICR小鼠的非特异性和特异性免疫功能,而其抗氧化功能有可能是其免疫调节活性的作用机制之一。 相似文献
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９５３口服液是由中药组成的复方制剂,经药效学实验表明,该制剂具有调整因放疗、化疗后引起的菌群失调和免疫功能低下的作用．为了进一步考察该制剂对其它系统的影响,我们用 ９５３口服液对小鼠神经系统、心血管系统、呼吸系统、急性毒性试验做了研究．结果表明,该制剂对其均无显著性影响,且Ｌ_（Ｄ５０）为 １１４．９０ｇ／ｋｇ,说明该制剂无毒无副作用,是一安全有效的微生态调整制剂． 相似文献
9.
孩子容易误服药物的原因很多,例如：孩子多喜欢吃糖果,又缺乏鉴别能力,有时把带有甜味和糖衣的药物当成糖果吃,有时又把有鲜艳颜色、芳香气味的水剂药物、化学制剂当饮料喝引起中毒。另外,幼儿好奇心强,模仿大人服药,也能酿成中毒。孩子一旦误服药物,会成倍或十几倍地超出剂量,而且有的药物对小儿敏感性高,婴幼儿解毒和排泄能力差,如不及时发现和处理,常常发生严重后果。发现孩子误服药物,正确的处理原则是：迅速排出,减少吸收,及时解毒,对症治疗。首先,尽快弄清什么时间,误服了什么药物和大体剂量,为就医提供依据,不要… 相似文献
10.
目的:研究慢肾宁片剂的制备方法及质量控制。方法:利用部分药物粉碎,部分药物水提浓缩的方法制备,从制剂的性状、鉴别、重量差异、崩解时限和稳定性考察等方面进行质量控制。结果:建立了慢肾宁片的制备方法和质量标准。结论:该制剂制备工艺合理,控制质量标准可行。 相似文献
11.
罗艳萍 《读与写:教育教学刊》2008,5(6)
The communication of people partially is the communication of cultures. Culture has a direct effect on international commercial activities in all aspects. Different conceptions about time, space, equality, law and the like, lead people to deal with things in different ways. So to know cultures of the counterpart is to facil-itate our enterprises so as to have a smooth and successful communication in commercial activity. 相似文献
12.
Richard Denner 《海外英语》2007,(4):14-15
Rosco and I wait for the fishermen to return.I sit at a wooden bench near the store at Mt.Baker Resort and watch the clouds change shape. Rosco has my belt around his neck and an eight foot tow chain hooked to a tree. Dogs must be on a leash. Ducks and rabbits are loose. 相似文献
13.
Given a graph G,a subgraph C is called a clique of G if C is a complete subgraph of G maximal under inclusion and |C|≥2. A clique-transversal set S of G is a set of vertices of G such that S meets all cliques of G. The clique-transversal number, denoted as TC (G), is the minimum cardinality of a clique-transversal set in G. The clique-graph of G, denoted as K (G), is the graph obtained by taking the cliques of G as vertices, and two vertices are adjacent if and only if the corresponding cliques in G have nonempty intersection. Let F be a class of graphs G such that F={G|K(G) is a tree}. In this paper the graphs in F having independent clique-transversal sets are shown and thus TC (G)/|G|≤1/2 for all G ∈ F. 相似文献
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《海外英语》2007,(5):10-11
Many college freshmen arrive woefully unprepared to do college work, and as disadvantaged populations continue to grow, the share of the American work force that has made it through college is expected to plummet. Many experts blame that educational failure not just on high schools but also on colleges. School & College, a special report by The Chronicle, looks at efforts to fix the system. What reforms would better prepare students for college? What should schools and colleges be doing differently? How should state and federal officials help? 相似文献
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陈美曦 《山东教育学院学报》2008,23(2):103-107
Different nations have different social cultures, and the social culture of every nation is developing with the development of the nation, language is greatly influenced by social culture, which enables language to possess national and historical characteristics. Word is the smallest, independent, meaningful linguistic unit of language. It can well reflect the national and historical characteristics. From synchronic aspect, the social and cultural influence on word meaning is mainly embodied in conceptual and associative meanings of word. The incorrespondence of word meaning is a phenomenon that exists in both conceptual and associative meanings of word among different languages. From diachronic aspect, the development of social culture causes some changes of word meaning to some extent. Therefore, social culture plays a key role in vocabulary learning and mastery of a language. 相似文献
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邱崇丙 《唐山师范学院学报》2014,(1):21-23
汉字的六书,《说文》对“转注”一类,语焉不详。后世学者提及转注,也仅限于许慎所举出的例字。《汉字例说》一文,作者从转注的角度综合考虑,对部分现代常用字作了分析,跟传统的解释有所不同。希望能抛砖引玉,互相切磋,以推进学术研究。 相似文献
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《海外英语》2007,(4):36
There are numbers of crossroads on our long and unpredictable life journey where we totally have no idea about which direction to choose. No matter what our decision is, we should not turn back, but face the music and go ahead instead. I am this kind of girl who always does try without regretting, one example is how I dealt with my love. 相似文献