共查询到20条相似文献，搜索用时 875 毫秒
1.
目的:观察舒筋汤对膝关节前交叉韧带(anterior cruciate ligament,ACL)损伤后关节镜下自体肌腱移植重建术后的临床疗效。方法:将60例患者随机分成二组,常规治疗组(对照组)以及常规治疗合舒筋汤组(综合组),对照组单纯在关节镜术后给予常规抗感染、镇痛及早期康复功能锻炼(术后常规治疗),综合组在术后常规治疗的基础上使用舒筋汤熏洗,四周为1疗程,治疗1个疗程后,随访2个月。结果:治疗后两组的中医证候积分及HSS评分均较治疗前有显著改善(P<0.05)。综合组中医证候积分改善优于对照组(P<0.05);综合组HSS膝关节功能评分中疼痛、功能、活动度、肌力及稳定性5项得分高于对照组(P<0.05);随访结束后综合治疗组的证候积分及HSS评分均较对照组改善明显(P<0.05)。综合组的疗效优于对照组(P<0.05)。结论:舒筋汤结合ACL损伤后关节镜下自体肌腱移植重建术后常规治疗可显著改善临床症状,并促进膝关节功能恢复。 相似文献
2.
目的:观察补肾活血法治疗血栓前状态复发性流产的临床疗效.方法:将80例存在血栓前状态的复发性流产患者,随机分为对照组和研究组各40例.对照组使用低分子肝素钠进行皮下注射治疗;研究组在对照组基础上加用补肾活血中药方进行治疗.观察比较两组血栓前状态标志物变化情况及孕12周存活率.结果:(1)研究组治疗后总有效率为95％,高于对照组的75％,差异有统计学意义(P＜0.05);(2)研究组孕12周胚胎存活率为95％,对照组为75％,组间孕12周胚胎存活率比较,差异有统计学意义,研究组明显高于对照组(P＜0.05);(3)研究组AT-Ⅲ水平较治疗前升高,D-二聚体、FIB水平较治疗前降低;且研究组AT-Ⅲ水平高于对照组,D-二聚体、FIB水平低于对照组,差异均有统计学意义(P＜0.05).结论:针对血栓前状态导致的复发性流产,采用补肾活血中药方联合低分子肝素钠,可改善患者的血栓前状态,改善妊娠结局. 相似文献
3.
目的:研究软肝散对慢性乙型肝炎肝纤维化的治疗效果.方法:选取180例慢性乙型肝炎患者为研究对象,随机分两组,治疗组给予益肝灵和软肝散口服,对照组给予益肝灵口服,治疗6个月后评定疗效.主要观察项目为治疗前后患者的临床症状、体征、肝功能(AST、ALT、A/G)和血清肝纤维化指标(HA、LN、PCⅢ、Ⅳ-C)的变化情况.结果:两组病例治疗后临床主要症状、体征、肝功能和肝纤维化指标较治疗治疗前均有较大改善,治疗组总有效率为91.11％,对照组总有效率为80％,治疗组效果明显好于对照组.结论:软肝散在治疗慢性乙型病毒性肝炎肝纤维化方面具有明显缓解临床症状和体征,改善肝功能及肝纤维化指标的作用,值得在临床上推广使用. 相似文献
4.
目的:探讨综合护理对冠心病患者健康行为和血脂水平的影响。方法:76例患者随机分为观察组和对照组,对照组32例给予常规心血管药物治疗和内科护理;观察组34例在此基础上给予综合护理干预,对两组患者分别在入院时和出院后5个月进行冠心病患者健康行为问卷调查和血脂检查。结果:两组控制体重、合理膳食、生活规律、戒烟限酒、运动锻炼、按时服药等健康行为项目比较,观察组显著优于对照组(P<0.05),观察组血脂指标TC、TG、LDL-L、HDL-L的改善显著优于对照组(P<0.05)。结论:综合护理干预能促使患者健康行为的形成,改善血脂水平,从而提高生活质量。 相似文献
5.
目的:明确小针刀疗法治疗青年腰椎间盘突出症的临床效果.方法:遵照随机数字表法,将60例青年腰椎间盘突出症的患者分为对照组及试验组,每组各30例,以小针刀疗法作为试验组治疗方法,以普通针刺疗法作为对照组治疗方法.测量两组治疗前及疗程结束后疼痛视觉模拟量表(Visual analogue scale,VAS)评分、日本骨科协会评估治疗分数(Japanese orthopaedic association,JOA)变化情况及临床症状的改善程度,并分析总结两组患者临床效果.结果:疗程结束后,经统计,90.00％为试验组总有效率,明显高于对照组73.33％的总有效率(P＜0.05).与治疗前比较,治疗后两组VAS评分较治疗前明显下降(P＜0.05),且试验组较对照组下降更明显(P＜0.05);两组治疗后JOA评分均明显高于治疗前(P＜0.05),且试验组较对照组升高更明显(P＜0.05).结论:小针刀疗法在青年腰椎间盘突出症患者临床治疗上确有较好效果,其具有快速缓解患者临床症状,恢复患者腰椎功能作用,值得临床研究及推广. 相似文献
6.
目的:探讨益气活血方对冠心病介入术后心脏功能与超敏C反应蛋白的相关性。方法:150例冠心病行PCI术患者按随机数字表法分为两组,对照组75例予西医常规药物治疗,治疗组75例在对照组治疗基础上予加服益气活血方,分别于入院时、出院后60d、出院后180d观察两组MIDAS评分、超声心动图结果、血清C反应蛋白的差异。两组治疗疗程为3个月,随访时间为6个月。结果:治疗后两组患者的生命质量和心功能均较入院时改善,但在出院后两组患者的心功能、血清C反应蛋白具有明显差异性,出院后180d时实验组的生命质量和心功能改善程度较对照组更为显著(P0.05)。实验组患者MIDAS评分在出院后180 d时明显高于对照组(P0.05);实验组患者血清超敏C反应蛋白在出院180 d后明显低于对照组;在6个月的随访中,超声心动图结果表明实验组左室射血分数、每搏出量、左室舒张、收缩末期内径改善较对照组明显(P0.05);在MACE发生率中,两组差异无统计学意义(P0.05)。结论:益气活血方能够改善PCI术后康复期患者的心功能,且益气活血方可以显著降低冠心病介入术后患者炎性因子血清超敏C反应蛋白水平。 相似文献
7.
目的:探讨钬激光内切开术联合球囊扩张术治疗输尿管狭窄的临床疗效.方法:将50例输尿管狭窄患者按随机数字表法分为观察组(25例)和对照组(25例),对照组予钬激光内切开术治疗,观察组在对照组的基础上联合球囊扩张术治疗,观察两组临床有效率、围手术期指标(手术时间、术中出血量、住院时间)、输尿管狭窄程度(狭窄长度、狭窄宽度、肾集合系统分离值)及并发症发生率.结果:经治疗后,观察组总有效率为96.00％,显著高于对照组的总有效率(75.00％)(P＜0.05);观察组输尿管狭窄改善程度和并发症发生率均明显优于对照组(P＜0.05);而两组在手术时间、术中出血量、住院时间上相近(P＞0.05).结论:钬激光内切开术联合球囊扩张术治疗输尿管狭窄的效果较为显著,可改善患者输尿管狭窄,减少术后并发症,值得推广应用. 相似文献
8.
《黑龙江科技信息》2020,(26)
目的:观察圆利针舌骨肌刺激疗法对脑瘫患儿流涎的临床疗效。方法:将符合纳入标准的60例脑瘫流涎患儿按随机数字表法分为观察组和对照组,每组30例,观察组采用圆利针刺激舌骨肌,对照组为常规中频治疗。治疗前、后利用教师流涎分级法、Sheppard的吞咽障碍调查问卷(DDS)对患儿流涎、吞咽障碍情况进行疗效评定。结果:治疗后观察组和对照组的流涎症状、吞咽功能均较治疗前改善(p0.05),观察组总有效率为,对照组总有效率为,观察组总有效率明显优于对照组,差异有统计学意义(p0.05)。结论:圆利针刺激舌骨肌疗法对治疗脑瘫患儿流涎、吞咽功能障碍疗效优于常规中频治疗。 相似文献
9.
目的:观察运用耳针配合灸法从肺肝脾治疗儿童分泌性中耳炎的临床疗效.方法:将82例儿童分泌性中耳炎患者随机分为治疗组和对照组各41例,对照组用鼻喷激素类药物喷鼻,口服孟鲁司特钠片、桉柠派软胶囊等西医疗法;治疗组在对照组基础上运用耳针配合灸法从肺肝脾经络入手辩证施治.比效两组临床疗效、纯音听阂变化等.分析临床疗效和纯音听阈、声导抗的改变情况.采用SPSS 18.0进行统计学分析.结果:(1)治疗组总有效率为95.12％,而对照组的总有效率为75.60％,两组比较,差异有统计学意义(P＜0.05).(2)治疗前,两组纯音听阈值都位于较高状态,两组间比较,差异无统计学意义(P＞0.05).治疗后,两组纯音听阈值都有较大幅度下降,治疗组纯音听阈值比对照组更低(P＜0.01).(3)两组治疗前后声导抗各型曲线变化显示中耳积液减少或消失,治疗组优于对照组(P＜0.01).结论:运用耳针配合灸法从肺肝脾辅助治疗儿童分泌性中耳炎较单纯西医治疗有明显优势,疗效更好,能改善个体微循环,减轻内耳循环障碍,促进咽鼓管功能恢复,使多数患者避免手术. 相似文献
10.
11.
用单克隆抗体MC_3在福尔马林固定的48例大肠癌、31例癌变腺瘤、42例伴有不典型增生腺瘤、40例腺瘤、13例息肉以及48例正常肠粘膜组织切片上用免疫组化(PAP)法检测,结果MC_3相应抗原的表达阳性率分别为93.8％(45/48)、80.65％ (25/31)、47.62％ (20/42)、37.5％(15/40),其阳性率差异有非常显著性(P<0.001).48例正常肠粘膜均为阴性.MC_3在大肠癌组织中的反应程度与患者3年生存率有关,差异有显著意义(P<0.05).MC_3反应强度在高分化肠癌组与中～低分化肠癌组比较差异有显著意义(P<0.05).在绒毛状腺瘤、混合性腺瘤和管状腺瘤中MC_3相应抗原表达阳性率分别为71.4％(25/35)、60.0％(9/15)、41.3(26/63),差异有显著性(p<0.05).绒毛状腺瘤、混合性腺瘤和管状腺瘤其癌变率分别为45.7％(16/35)、13.3％(2/15)、20.6％(13/63),其癌变率比较差异有显著性(P<0.05). 相似文献
12.
对５６例消化性溃疡患者，平分两组分别用奥美拉唑及进口洛赛克治疗４周。结果：奥美后唑总有效率９６％，洛赛克１００％，两者差异无显著性；两组治疗前后快速尿素酶试验阳性率相比差异无显著性；治疗前与治疗后胃液ｐＨ值相比两组差异均有高度显著性。奥美拉唑费用低，有推广价值。 相似文献
13.
Jain A Mal J Mehndiratta V Chander R Patra SK 《Indian journal of clinical biochemistry : IJCB》2011,26(1):78-81
Vitiligo is an idiopathic, acquired, circumscribed, hypomelanotic skin disorder, characterized by milky white patches of different
sizes and shapes. It is due to the destruction of melanocytes resulting in the absence of pigment production of the skin and
mucosal surfaces. Oxidative stress has been implicated in pathophysiology of vitiligo. To study the activity of blood Superoxide
dismutase (SOD) and Glutathione peroxidase (GPx) in vitiligo patients. A case–control study was conducted in which 100 patients
were enrolled after written consent. 50 cases were of active vitiligo and 50 served as control (25 healthy control and 25
with stable vitiligo). SOD—In our study, among the active vitiligo cases 90% had high level of SOD and 10% had normal level
of SOD. Among the stable vitiligo controls, 92% had normal level of SOD and 8% had low levels of SOD.The difference between
active vitiligo cases and stable vitiligo control as well as with healthy control was statistically significant (P value < 0.05). GPx—Among the active vitiligo cases 74% had normal GPx levels, 22% had low and only 4% had high levels of
GPx. Among the stable vitiligo controls, 64% had normal GPx levels, 16% had low, and 20% had high levels of GPx. The difference
between active vitiligo cases and stable vitiligo control as well as with healthy control was statistically not significant
(P value > 0.05). Our study shows that oxidative stress is involved in the pathophysiology of vitiligo, as indicated by the
high levels of serum superoxide dismutase activity. 相似文献
14.
Yonas Mullugeta Rajinder Chawla Tedla Kebede Yesehak Worku 《Indian journal of clinical biochemistry : IJCB》2012,27(4):363-369
The nature of the dyslipidemia associated with diabetes mellitus is complex and is the major risk factor for atherosclerosis and coronary artery disease. Aim of this study was to assess the effect of glycemic control, achieved by metformin, glibenclamide and insulin, on lipid profile in type 2 diabetic patients. One hundred and sixty-five type 2 diabetes mellitus patients were classified into good glycemic control (Group I) and poor glycemic control (Group II) on the basis of their blood HbA1c values. The Group II was characterized with high serum triglyceride (190.46 ± 15.20 mg/dl), total cholesterol (175.3 ± 6.31 mg/dl) as well as high LDL-cholesterol (109.0 ± 5.88 mg/dl). Significant correlations were evident between HbA1c and dyslipidemia, particularly serum TG (r = 0.28, P < 0.05), and between HbA1c and total cholesterol (r = 0.310, P < 0.05). Better glycemic control and improved dyslipidemia were observed in patients on combination therapy of metformin plus glibenclamide. 相似文献
15.
K. Sri Manjari Pratibha Nallari A. Vidyasagar A. Jyothy A. Venkateshwari 《Indian journal of clinical biochemistry : IJCB》2012,27(2):152-156
Chronic pancreatitis (CP) presenting clinically with upper abdominal pain, as well as exocrine and endocrine insufficiencies, is characterized by irreversible morphological and functional alterations in the pancreas. The objective of the present study is to investigate the plasma levels of transforming growth factor-β 1 (TGF-β1), matrix metalloproteinases MMP-1 (collagenase) and MMP-3 (stromelysin) in CP. A total of 71 CP patients and 100 control subjects were considered for the study. Plasma levels of TGF-β1, MMP-1 and MMP-3 were determined by enzyme-linked immunosorbent assay in patients and control subjects. The plasma levels of TGF-β1 and MMP-1 were significantly elevated in patients compared to control group (*P = 0.0301, **P < 0.0001). However, there was no significant difference in the plasma levels of MMP-3 between patients and controls (P = 0.3756). The elevated levels of TGF-β1 and MMP-1 may influence the inflammatory reactions by enhancing the pancreatic stellate cell activation and deposition of extracellular matrix resulting in pancreatic fibrosis. Thus, the present study highlights the role of fibrogenic cytokine marker TGF-β1 and matrix metalloproteinases in the pathogenesis of CP. 相似文献
16.
Suparna Roy Ushasi Banerjee Anindya Dasgupta 《Indian journal of clinical biochemistry : IJCB》2016,31(1):43-49
In conjunction with thyroxine, bilirubin may play an important role for regulation of hsCRP level and a consequent pro-inflammatory condition in hypothyroidism. In present study we evaluated the dependence of hsCRP changes on total bilirubin (BT) and fT4 level in thirty overt (OH) and thirty subclinical hypothyroidism (SH). Serum BT, hsCRP, thyroxine and TSH were measured in both groups and compared with forty control subjects. Serum values of TSH, hsCRP showed raised (P < 0.001 for both) values with lower levels for fT4 and BT (P < 0.001 and 0.03 respectively) in hypothyroid patients compared to the controls. ANOVA showed significant increments in TSH and hsCRP values with decreases in fT4 among the control, SH and OH groups respectively (P < 0.001). BT values showed decrease in OH group only in comparison to controls (P = 0.04). Regression analysis revealed that hsCRP was negatively dependent on fT4 (β = −0.35, P = 0.002) and serum bilirubin (β = −0.40 and P < 0.001 respectively). Univariate general linear model analysis showed this dependence persisted even when carried out distinctly in SH and OH groups separately (P < 0.001). TSH did not show any significant predictive value on the hsCRP level in either of these two tests. From these analyses we suggest that serum hsCRP is closely integrated to a lowered synthesis of bilirubin and fT4 in hypothyroid patients. Furthermore, this causal relationship is not only limited to overt but also extends to the SH. 相似文献
17.
半导体激光治疗慢性牙髓炎和慢性根尖周炎 总被引：4，自引：0，他引：4
为探讨利用半导体激光治疗慢性牙髓炎和慢性根尖周炎的新办法,使用半导体激光光源及单模光纤将激光引入根管,对１２８只牙根管进行照射,并与常规根管治疗术进行对照比较,结果表明,激光治疗慢性牙髓炎和慢性根尖周炎组治愈率分别为９６．１５％和９４．７４％,疗效优于对照组,经统计学检查有显著性差异。 相似文献
18.
Surupa Basu Ruchi Gupta Monjori Mitra Apurba Ghosh 《Indian journal of clinical biochemistry : IJCB》2015,30(2):167-173
Vitamin D deficiency is highly prevalent in Indian children of northern, western and southern states. Serum 25 hydroxy cholecalferol (ng/ml) was analyzed in 310 children and adolescents of pediatric hospital of Kolkata, India. Serum calcium (mg/dl), phosphorous (mg/dl) and alkaline phosphatase (IU/L) data was obtained. Median 25(OH)D was 19 ng/ml. 19.2 % of population had serum 25(OH)D < 10 ng/ml (severe deficiency), 52.9 % had <20 ng/ml (deficiency), 24.5 % had 20–29 ng/ml (insufficiency) and 22.6 % had >30 ng/ml (optimum). Deficiency was highest in adolescents (86.1 %), followed by school children (61.0 %), lowest in pre-school children (41.6 %). 25(OH)D concentrations was lowest in winters (P = 0.002) and spring (P = 0.03) compared to summer. There was no correlation with calcium (P = 0.99), phosphorous (P = 0.23) and ALP (P = 0.63). There is high prevalence of vitamin D deficiency in children and adolescents of eastern India. Prevalence was lower in younger subjects. 25(OH)D did not correlate with bone mineral markers. 相似文献
19.
目的:分析“基础护理学”实验课的教学方法,以及在自主互助、合作探究教学模式下的实践应用效果。方法:以贵州中医药大学护理学院2017级、2018级本科护理一班和护理二班的学生共计341人为研究对象,其中2017级的172人作为本次研究的对照组,2018级的169人作为观察组。针对对照组安排传统的“基础护理学”教学方法,针对观察组则安排学生自主互助、合作探究教学模式的实践应用,对比这两组学生的技能考核情况、理论考核情况及两组学生的综合能力成绩。结果:除监测生命体征这项操作外,观察组学生的技能考核各项成绩都要明显优于对照组(P<0.05);观察组学生的理论知识考核成绩达到了(38.55±2.57)分,而对照组只有(35.55±2.57)分,两组差异明显,具有统计学意义(t=2.58,P<0.01);除关爱及同学情感这2项外,观察组学生通过该教学模式明显提升了自主互助、合作探究等各项学习能力,差异具有统计学意义(P<0.05)。结论:在“基础护理学”实验教学课程中应用自主互助、合作探究教学模式,能够更好地提升教学效果,有利于培养更多高素养、实践能力强的当代护理人才,值得推广与借鉴。 相似文献
20.
为探讨力平脂对血液流变学的影响，选择了４６例高脂血症及／或各类心脏病患者，服力平脂胶囊０．１，ＴｉＤ，连服二月为一疗程（治疗组），选择２３例高脂血症及／或各类心脏病患者，服金水宝胶囊０．９９，Ｔｉｄ，连服二月为一疗程（对照组），对比观察对不同性别病人的红细胞压积、血沉、全血粘度（从高切到低切）的影响，发现两组男性患者治疗后的红细胞压积和血沉的改变差异不显著，全血比粘度治疗组明显优于对照组，女性患者 相似文献