共查询到20条相似文献,搜索用时 93 毫秒
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β-内酰胺类抗生素是20世纪的伟大发明之一,拯救了数以万计生命.然而,随着抗生素临床应用的普及,由β-内酰胺酶导致的致病菌耐药性问题也日益突出.耐药菌的进化和传播严重影响到人类健康和全球社会经济发展.因此,检测/抑制β-内酰胺酶的活性对合理使用抗生素、有效治疗感染类疾病具有重要意义.目前,特异性检测、抑制β-内酰胺酶的相关方法和临床应用已有报道.本综述主要阐述细菌产生β-内酰胺酶的耐药机理,总结近年来β-内酰胺酶荧光探针和抑制剂的发展,以期为今后设计特异性高、灵敏度强的该类荧光探针和抑制剂提供理论依据,解决抗生素耐药性问题. 相似文献
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牛乳中抗生素的残留与危害现状 总被引:11,自引:0,他引:11
抗生素越来越多地被应用于畜牧业中,其在乳制品中的残留问题也备受关注.乳品中残留抗生素不仅危害人体的健康,而且会影响经济贸易的正常进行.为了让广大民众及企业对牛乳中抗生素残留问题有更深的了解,章从牛乳中抗生素的残留来源、危害、现状、管理及检测方法等方面进行综述,以期提高民众的消费意识和牛乳生产的商业道德水平,保障消费的权益. 相似文献
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刘平 《荆门职业技术学院学报》2003,18(6):75-77
目的:综述59种抗生素类药品的显色反应,为药品监督检验提供快速检验方法.方法:事先配制好13种试液,利用化学显色反应,对常见的59种抗生素84种剂型进行检验.结果:不同种类的药品。显其特有的颜色,如有不同,则可疑为假劣药品.结论:方法简便、快速,鉴别假劣药品的准确率高. 相似文献
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青霉烯类抗生素及其构效关系 总被引:1,自引:0,他引:1
青霉烯 ,是一类抗菌谱广 ,抗菌活性高 ,对肾脱氢肽酶 -I稳定的抗生素 ,本文介绍了青霉烯类抗生素的特征、抗菌性及其活性的构效关系 ,交介绍了用分子力学和分子轨道方法对其效关系进行的理论阐述。 相似文献
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为了解凯里地区动物肝肾组织中抗生素残留量的状况,应用高效液相色谱法进行了测定,测定结果显示动物肝肾组织中抗生素残留量存在超标现象. 相似文献
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微机运算(2.2)法抗生素微生物检定刘学军,刘迎元目前.许多单位没有足够的资金购置ZY—300A型多功能抑菌圈自动测试仪。但是.如果能充分利用微机的计算功能来运算(2.2)法抗生素微生物检定.也不乏是一种迅速准确计算抗生素效价及统计分析实验结果的好办... 相似文献
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泉州市售牛奶中抗生素残留的分析 总被引:2,自引:0,他引:2
为了解和比较泉州市市售生牛奶及消毒纯牛奶中抗生素残留情况,从泉州市不同区域及两个奶牛场采集生牛奶150份.几大超市采购消毒纯牛奶100份.按国家标准GB/T4789.27-2003,采用TTC法进行检测,检测出生牛奶中阳性27份,可疑15份,阳性率18%,可疑率10%;国产消毒纯牛奶75份,阳性14份,阳性率18.7%;进口纯牛奶25份,阳性0份,阳性率0%,调查结果显示,本市产的生牛奶中抗生素残留阳性率比国产消毒纯牛奶高,牛奶中抗生素残留的情况仍较为严重,应引起广大消费者的注意,并倡议政府部门应加强对食品安全的管理和执行力度,以尽快改善此现状。 相似文献
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随着科学技术的不断进步与发展,在人类与疾病相互斗争的长河中,致病性生物茵与人类抗生素的使用一直处于演变与发展之中.新的抗生素不断出现和使用为感染性疾病的治疗提供了有利的武器,但同时人类长期、大量的使用抗生素,也使得致病茵对抗生索逐渐发生适应,产生了耐药性,这将是人类面临的严峻问题. 相似文献
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罗艳萍 《读与写:教育教学刊》2008,5(6)
The communication of people partially is the communication of cultures. Culture has a direct effect on international commercial activities in all aspects. Different conceptions about time, space, equality, law and the like, lead people to deal with things in different ways. So to know cultures of the counterpart is to facil-itate our enterprises so as to have a smooth and successful communication in commercial activity. 相似文献
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邱崇丙 《唐山师范学院学报》2014,(1):21-23
汉字的六书,《说文》对“转注”一类,语焉不详。后世学者提及转注,也仅限于许慎所举出的例字。《汉字例说》一文,作者从转注的角度综合考虑,对部分现代常用字作了分析,跟传统的解释有所不同。希望能抛砖引玉,互相切磋,以推进学术研究。 相似文献
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Richard Denner 《海外英语》2007,(4):14-15
Rosco and I wait for the fishermen to return.I sit at a wooden bench near the store at Mt.Baker Resort and watch the clouds change shape. Rosco has my belt around his neck and an eight foot tow chain hooked to a tree. Dogs must be on a leash. Ducks and rabbits are loose. 相似文献
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Given a graph G,a subgraph C is called a clique of G if C is a complete subgraph of G maximal under inclusion and |C|≥2. A clique-transversal set S of G is a set of vertices of G such that S meets all cliques of G. The clique-transversal number, denoted as TC (G), is the minimum cardinality of a clique-transversal set in G. The clique-graph of G, denoted as K (G), is the graph obtained by taking the cliques of G as vertices, and two vertices are adjacent if and only if the corresponding cliques in G have nonempty intersection. Let F be a class of graphs G such that F={G|K(G) is a tree}. In this paper the graphs in F having independent clique-transversal sets are shown and thus TC (G)/|G|≤1/2 for all G ∈ F. 相似文献
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《海外英语》2007,(5):10-11
Many college freshmen arrive woefully unprepared to do college work, and as disadvantaged populations continue to grow, the share of the American work force that has made it through college is expected to plummet. Many experts blame that educational failure not just on high schools but also on colleges. School & College, a special report by The Chronicle, looks at efforts to fix the system. What reforms would better prepare students for college? What should schools and colleges be doing differently? How should state and federal officials help? 相似文献
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陈美曦 《山东教育学院学报》2008,23(2):103-107
Different nations have different social cultures, and the social culture of every nation is developing with the development of the nation, language is greatly influenced by social culture, which enables language to possess national and historical characteristics. Word is the smallest, independent, meaningful linguistic unit of language. It can well reflect the national and historical characteristics. From synchronic aspect, the social and cultural influence on word meaning is mainly embodied in conceptual and associative meanings of word. The incorrespondence of word meaning is a phenomenon that exists in both conceptual and associative meanings of word among different languages. From diachronic aspect, the development of social culture causes some changes of word meaning to some extent. Therefore, social culture plays a key role in vocabulary learning and mastery of a language. 相似文献
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Rachel Zupek 《海外英语》2007,(11):40-41
我们绝大部分人都同意一件事情——我们喜欢金钱。但是你对金钱的喜欢之情足够到让你创立一份事业么?.财富通常被人忽视,主要在于人们不能真正了 相似文献
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YANGShiguo 《重庆大学学报(英文版)》2004,3(1):86-88
The problem on the geometrc inequalities involving an n-dimensional simplex and its inscribed simplex is studied. Aninequality is established, which reveals that the difference between the squared circumradius of the n-dimensional simplex andthe squared distance between its circumcenter and barycenter times the squared circumradius of its inscribed simplex is not lessthan the 2(n-1)th power of n times its squared inradius, and is equal to when the simplex is regular and its inscribed siplex is atangent point one. Deduction from this inequality reaches a generalization of n-dimensional Euler inequality indicating that thecircumradius of the simplex is not less than the n-fold inradius. Another inequality is derived to present the relationship betweenthe circumradius of the n-dimensional simplex and the circumradius and inradius of its pedal simplex. 相似文献