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1.
Intake of a 0.15% saccharin solution was suppressed when it was followed by a 32% sucrose solution in brief daily pairings. With equal access durations to the two solutions, intervals of intermediate duration (2 or 3 min) produced a larger contrast than more extreme intervals (1 or 10 min). There was no evidence of inhibition of delay with the 10-min interval (Experiments 1A and 1B). When access times were asymmetrical, longer access time to the first solution reduced contrast, whereas longer access time to the second solution enhanced contrast (Experiment 2). Contrast was greater when the two solutions were presented at consistent and separate spatial locations than when location was changed randomly or when both solutions were presented in sequence at the same location. However, a degree of contrast occurred in all conditions (Experiment 3). Experiment 4, conducted with the solutions in opposite arms of a T-maze, showed that anticipatory approach to the location correlated with the 32% sucrose solution developed prior to lick suppression on the saccharin solution. However, within daily sessions, there was a reliable increase in contrast without correlated changes in anticipatory-approach behavior. Access-time effects were attributed to altered reward values, whereas spatial-separation effects suggest that goal-directed responses contribute to, but do not cause, anticipatory contrast.  相似文献   

2.
In three experiments, the time horizon over which the rat evaluates alternative feeding sources was investigated. The time horizon was measured by the suppression of intake of one incentive (a 0.15% saccharin solution) when a preferred alternative incentive (a 32% sucrose solution) was available but delayed. In Experiment 1, we found a direct function between the amount of saccharin intake and the delay time before access to 32% sucrose. Compared with intake for a saccharin-only control, saccharin intake was suppressed before 4-min and 16-min sucrose delays, but not before a 32-min delay. Because previous work (Flaherty & Checke, 1982) had reported suppression before a delay of nearly 32 min, in the subsequent experiments we examined factors that might account for this difference. In Experiment 2, we found that saccharin intake was suppressed before a 32-min delay interval when saccharin and sucrose solutions were presented in a bright-novel test environment but not when the same solutions were presented in the home cage. In Experiment 3, we found that the time between testing and subsequent postsession feeding could also affect the suppression of saccharin intake. Saccharin intake was suppressed when access to 32% sucrose was delayed by 32 min and the test situation was followed by immediate postsession feeding, but not when postsession feeding was delayed by 90 min. These results thus extend estimates of the rat’s time horizon to at least 32 min, but indicate that the effective time horizon can vary, depending on the test situation.  相似文献   

3.
In four experiments, the once daily availability of saccharin (.15%) preceded the availability of sucrose (32% or 2%). Experiment 1 showed that the intake of saccharin was reduced when it preceded 32% sucrose but not when it preceded 2% sucrose, as compared with saccharin-alone conditions. Experiment 2 showed that less saccharin was consumed when the saccharin preceded sucrose by 5 min than when there was a 30-min intersolution interval. Experiment 3 replicated this finding and showed that the presentation of the two solutions through the same or different access holes in the apparatus was not relevant to the result. Experiment 4 showed that there was an inverse relationship between saccharin intake and the length of the intersolution interval in the range of 1 to 30 min. These data were interpreted to indicate that the animals learn the predictive relationship between the saccharin and sucrose solutions and that the intake of the saccharin is reduced by an anticipatory contrast mechanism—a mechanism that may have restricted temporal parameters.  相似文献   

4.
Animals poisoned following exposure to saccharin subsequently avoided the schedule-induced consumption of saccharin. While this suppression was transient for subjects who had access only to the saccharin solution during the free-food presentations, recovery of schedule-induced saccharin consumption was significantly retarded for subjects who had concurrent access to saccharin and a running wheel. It has been suggested that the transient suppression of schedule-induced polydipsia by conditioned taste aversions results from the pellet-induced tendency to drink within the schedule-induced polydipsia procedure. That access to the running wheel reduces schedule-induced polydipsia in general and prolongs the suppression of schedule-induced polydipsia by taste aversions supports this view.  相似文献   

5.
Previous experiments have shown that the negative contrast effect in consummatory behavior that occurs when rats are shifted from 32% to 4% sucrose is alleviated by the tranquilizer chlordiazepoxide (CDP). However, in these experiments, CDP was effective on the second postshift day but not on the first postshift day. The three experiments described in this paper suggest that this differential effectiveness of CDP is not due to the difference in preshift-postshift retention intervals on Day 1 (24 h) and Day 2 (48 h), but is due instead to the necessity of some degree of experience (about 5 min) with the postshift solution. These results, combined with those of an earlier study which showed elevated corticosterone in shifted animals on the second postshift day but not on the first postshift day, suggest that negative contrast may be a dynamic process, involving sequential processes of detection, evaluation, and conflict over the postshift period. It was further suggested that CDP becomes effective in moderating contrast only when the conflict stage is reached.  相似文献   

6.
In four experiments, food deprivation was varied during conditioning and testing of conditioning of flavor preferences by sweeteners. Conditioned preferences for a flavor associated with a more concentrated solution were enhanced by increased deprivation in training whether sucrose or saccharin was used when rats consumed solutions freely during training. When consumption of solutions was controlled and higher deprivation levels were used, preference for the higher concentration of sucrose was still enhanced by increased deprivation in training, but this did not occur with saccharin. We suggest that deprivation may enhance the reinforcing value of sweetness only when calories increase along with sweetness. We also suggest that deprivation can enhance flavor preference learning by increasing consumption and thereby increasing exposure to the flavored solutions.  相似文献   

7.
Extinction of a conditioned palatability shift preceded extinction of conditioned taste avoidance whether rats were tested using a within-subjects design or a between-subjects design. In each of two experiments, consumption of 0.1% saccharin was paired with either 20 ml/kg of 0.15 M LiCl or equivolume physiological saline on a single trial. In Experiment 1, on each of 10 extinction trials, rats were given a taste reactivity test immediately prior to a consumption test. In Experiment 2, half of the rats were extinguished by taste reactivity testing and half of the rats were extinguished by a consumption test on each of 10 extinction trials. In both experiments, the aversive reactions of gaping and passive dripping were extinguished in a single trial and the suppression of ingestive reactions was extinguished in 2 trials; however, extinction of taste avoidance required 4–5 trials. These results suggest that rats continue to avoid a lithium-paired flavor even when they do not have an aversion to the taste.  相似文献   

8.
The effects of select drugs, dosages, and modes of administration upon learned taste aversions were compared among groups of wild-caught male and female Philippine rice rats (R. r. mindanensis). Experiment 1 compared two-choice saccharin aversions for 28 days among groups intubated with copper sulfate, cyclophosphamide, lithium chloride, red squill, sodium chloride (control), or deionized water (control). Main results were that 375 mg/kg lithium chloride produced the greatest sustained aversions, whereas 198 mg/kg cyclophosphamide and 210 mg/kg red squill produced moderate aversions, with males showing more resistance to extinction than females. Experiment 2 compared saccharin aversion among matched groups of male and female rats that received low (36 mg/kg), moderate (105 mg/kg), or high (368 mg/kg) dosages of lithium by gavage, ip injection, or ingestion. Sex differences in rates of extinction were found for the ingestion and injection-dosed rats, but no sex difference was again found for rats dosed by gavage. A significant mode × day interaction indicated that extinction progressed more rapidly for rats dosed by gavage. For all modes of administration, high dosages yielded intense 28-day aversion, moderate dosages produced intermediate 3–5 day aversion, and low dosages caused no aversion.  相似文献   

9.
Morphine failed to condition a salt taste aversion at a dose (15 mg/kg) sufficient to produce a robust aversion to a saccharin taste. Indeed, three different concentrations of salt (1%, 1.5%, and 2%) paired with the same morphine dose yielded no direct evidence for conditioned aversion. Yet, when a novel saccharin taste was paired in compound with the previously conditioned salt conditioned stimulus, we found evidence for a conditioning to the saccharin cue alone in three separate experiments. Control groups eliminated alternative accounts such as neophobia and differential exposure to morphine. Combined, these findings indicate that morphine conditioned a salt aversion. Although this aversion was not directly expressed, a second-order conditioning procedure was able to provide a more sensitive index of conditioning.  相似文献   

10.
Two experiments examined the effects of nonreinforced flavor exposure on the strength of a conditioned taste aversion. Rats were conditioned by pairing maple flavor with LiC1. Prior to or subsequent to this pairing, some animals received nonreinforced exposure to either maple or saccharin. In separate subjects, preference for maple was tested 1 or 21 days after the last training episode. In the first experiment, the nonreinforced stimulus exposure occurred before conditioning (latent inhibition, or LI, procedure); in the second experiment, the nonreinforced exposure occurred after conditioning (extinction, or EXT, training). In both experiments, nonreinforced exposure to maple or saccharin reduced the magnitude of a conditioned maple aversion when testing occurred soon after conditioning. When testing was delayed, however, the attenuation due to nonreinforced saccharin exposure dissipated, both with the LI procedure and with EXT. In contrast, the nonreinforced exposure to maple was found to attenuate conditioned reactions at both short and long retention intervals. The release from generalized LI and spontaneous recovery following generalized EXT training are discussed in terms of retrieval processing. The possibility that the same mechanism may underlie LI and EXT is considered.  相似文献   

11.
In two experiments, rats (n = 228) received pretraining access to a distinctive novel flavor (saline) followed by aversion conditioning to a different novel conditioned stimulus (CS) (saccharin). Then the rats were tested for aversion to the CS (saccharin) or for conditioning-enhanced neophobia to a third novel flavor (casein hydrolysate). Pretraining access to a distinctive novel flavor that differed from the CS reliably reduced the magnitude of conditioning-enhanced neophobia to casein, but did not reliably affect conditioned aversion effects to the CS. Pretraining access to the CS reduced aversion effects to the CS and reduced postconditioning neophobia to casein to the performance level shown by ingestion-toxin controls. Results were consistent with the view (Braveman & Jarvis, 1978) that conditioned aversion and neophobia may be independent phenomena with separable underlying mechanisms.  相似文献   

12.
Avoidance of a target flavor can be produced by providing rats with a highly nutritious solution of 20?% maltodextrin (20?%Malto) in some sessions and a 3?% maltodextrin (3?%Malto) solution containing the target flavor in intermixed sessions. Since 20?%Malto is both more nutritious and more palatable than 3?%Malto, flavor avoidance could arise because the flavor signals either a reduction in calories or reduced palatability, or both. Pilot testing established that rats strongly preferred 3?%Malto plus 0.1?% saccharin to both unflavored 3?%Malto and unflavored 20?%Malto. The two main experiments tested whether the palatability difference, which the pilot data had suggested was larger than the difference between 20?%Malto and 3?%Malto, could produce flavor avoidance. In both experiments, one group of rats were given 3?%Malto plus 0.1?% saccharin on some days, intermixed with other days on which this group was given 3?%Malto plus the target flavor, almond. Neither when trained and tested under conditions of food deprivation (Experiment 1) nor when trained and tested sated (Experiment 2) did palatability reduction produce almond avoidance. In contrast, calorie reduction produced almond avoidance under both conditions. These results suggest that flavor avoidance can be produced by intermixed training involving solutions that differ in nutritious value and palatability, but not when they differ only in palatability.  相似文献   

13.
The literature relevant to incentive contrast effects is reviewed, with emphasis on the data published since the reviews by Black (1968) and Dunham (1968). Contrary to the evidence available for the earlier reviews, the current literature indicates that positive contrast is a reliable phenomenon. Its occurrence is facilitated by use of a constant delay of reward, use of a long runway, or possibly by a shift while a negative contrast effect, resulting from a previous shift, is still present in the animals’ behavior. Positive contrast also occurs in consummatory behavior when sucrose or saccharin solutions are shifted. Conditions that are ineffective in producing positive contrast are reviewed, as are the effects of numerous variables on both successive and simultaneous contrast. In addition, positive and negative contrast effects resulting from shifts in delay or percentage of reward, contrast resulting from shifts in sucrose, saccharin, or ethanol solutions, contrast in choice behavior, and transsituational contrast are reviewed. The relationship of the data to several theoretical interpretations of contrast is also considered.  相似文献   

14.
Rats repeatedly injected with lithium chloride were subsequently tested drinking novel and familiar solutions of both casein hydrolysate and vinegar. Injections in the absence of edibles result in only a small, and sometimes not reliable, increased avoidance of the novel casein and vinegar solutions. In contrast, if subjects acquired an aversion to saccharin as a result of the lithium injections, this learned aversion generalized to casein hydrolysate, with the generalization greatly enhanced by novelty of the casein flavor. However, the saccharin aversions did not generalize to the novel vinegar solution nearly as much as to the novel casein flavor. These results suggest that previous observations of poison-induced neophobia were probably in part a result of the stimulus generalization of conditioned taste aversions and that in addition to test stimulus novelty some other factor, such as stimulus salience or similarity to the conditioned aversive flavor, is also involved in the generalization of learned taste aversions.  相似文献   

15.
Four experiments examined whether or not spontaneous recovery could occur after extinction in the conditioned taste-aversion paradigm. After three extinction trials, spontaneous recovery was obtained over an 18-day retention interval (Experiments 1, 2, and 3). The effect was not due to changes in the unconditioned preference for saccharin over the retention interval (Experiment 2) or to an increase in a nonextinguished aversion over time, as indicated by tests with both the original, nonextinguished aversion (Experiment 1) and with a weaker one (Experiment 3). Spontaneous recovery was not obtained when extinction was overtrained (eight trials) and a 49-day retention interval was used (Experiment 4). However, saccharin intake at asymptote reached the level of baseline water intake, and not the highly preferred level shown by never-conditioned controls. Results of all four experiments suggest that extinction does not return an averted taste to the status of an unconditioned one.  相似文献   

16.
In five conditioned taste aversion experiments with rats, summation, retardation, and preference tests were used to assess the effects of extinguishing a conditioned saccharin aversion for three or nine trials. In Experiment 1, a summation test showed that saccharin aversion extinguished over nine trials reduced the aversion to a merely conditioned flavor (vinegar), whereas three saccharin extinction trials did not subsequently influence the vinegar aversion. Experiment 2 clarified that result, with unpaired controls equated on flavor exposure prior to testing; the results with those controls suggested that the flavor extinguished for nine trials produced generalization decrement during testing. In Experiment 3, the saccharin aversion reconditioned slowly after nine extinction trials, but not after three. Those results suggested the development of latent inhibition after more than three extinction trials. Preference tests comparing saccharin consumption with a concurrently available fluid (water in Experiment 4, saline in Experiment 5) showed that the preference for saccharin was greater after nine extinction trials than after three. However, saccharin preference after nine extinction trials was not greater, as compared with that for either latent inhibition controls (Experiments 4 and 5) or a control given equated exposures to saccharin and trained to drink saline at a high rate prior to testing (Experiment 5). Concerns about whether conditioned inhibition has been demonstrated in any flavor aversion procedure are discussed. Our findings help explain both successes and failures in demonstrating postextinction conditioned response recovery effects reported in the conditioned taste aversion literature, and they can be explained using a memory interference account.  相似文献   

17.
In three experiments, the learning of flavor preferences due to pairing with calories was examined. In Experiment 1, the relative hedonic values of four isocaloric solutions and saccharin were assessed by offering these substances simultaneously to naive rats. The caloric solutions were then used to condition a flavor preference in separate groups of rats. Although the solutions were reliably different in unconditioned hedonic value, the conditioned flavor preferences were identical. In Experiment 2, we compared solutions of sucrose and saccharin that were equal in unconditioned hedonic value. Only the sucrose conditioned a preference. Finally, in Experiment 3, preferences were found to be sensitive to the number of calories available during conditioning. These results are discussed in terms of a peripheral cholecystokinin (CCK) reflex and the integration of that information along with taste information at the area postrema (AP) and surrounding nuclei. It is proposed that CCK acts centrally to adjust the incentive motivation or hedonic value of flavors.  相似文献   

18.
Two experiments with rat subjects examined whether a saccharin taste could potentiate the conditioning of an aversion to a salty taste when the two stimuli were presented together prior to lithium-induced illness. In Experiment 1, a 0.1% (w/v) saccharin solution potentiated conditioning of a very dilute (0.03%) NaCl solution, but had no demonstrable effect on two stronger NaCl solutions (0.6% and 1.2%). In Experiment 2, the 0.1% saccharin solution again potentiated the 0.03% NaCl target, but weaker and stronger saccharin concentrations (0.033% and 0.3%) did not. The ability of a taste to potentiate a secondtaste is not consistent with theories that assume that potentiation is unique to compounds composed of tastes and other, functionally different, nontaste cues. Potentiation may occur when the target stimulus is weakly conditionable on its own and when the particular combination of target and potentiator facilitates perceptual integration of the compound.  相似文献   

19.
In five experiments, rats’ preference for a flavor was greater if the flavor had previously been consumed under low rather than high deprivation. This preference was conditioned in as few as three flavor-deprivation pairings (Experiment 1), and persisted through 28 test days, half under each deprivation level (Experiment 2). Rats never preferred the flavor associated with high deprivation even when calories were increased by giving 40 ml of 8% sucrose or when caloric density was increased to the equivalent of 20% sucrose. The preference for the low-deprivation flavor was greater when saccharin solutions were used rather than sucrose solutions, but the preference did emerge when sucrose solutions were used as testing proceeded and when a lower concentration of sucrose was used. We suggest that these preferences may be a result of flavor-taste associations rather than associations between flavors and postingestive consequences, and that the taste of the solutions under low deprivation is preferred to the taste under high deprivation.  相似文献   

20.
In three experiments, rats were presented compound solutions consisting of a common element, saccharin, mixed with one of two different flavor elements, cinnamon and wintergreen. Rats in the experimental groups consistently received a toxicosis-inducing injection following one compound solution but not following the other compound solution. Rats in the control groups received toxicosis-inducing injections half the time following each of the compound solutions. After training in each experiment, there were tests for conditioning to the saccharin alone. The experimental groups drank significantly more than the control groups, indicating that the aversion to the partially reinforced saccharin in isolation was less when the different flavor cues were more highly correlated with reinforcement. In Experiment III, there was also a test for conditioning to the cinnamon or wintergreen flavor alone. The experimental group drank significantly less of the continuously reinforced flavor than the control group did of the partially reinforced flavor. These results are similar to those reported within more traditional conditioning paradigms.  相似文献   

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