共查询到20条相似文献，搜索用时 93 毫秒
1.
近年来子宫内膜异位症的发病率有不断增高趋势.我院对1990年1月1992年12月收治的经手术及病理证实的子宫内膜异位症127例进行了分析,其发病率占同期妇科腹部手术的11.1%。发病年龄以31—45岁居多,占87%。子宫内膜异位症的临床表现并非特异性,常被误诊.我院术前误诊率为57.15%;故提出应提高诊断率.本文对发病因素进行了探讨,通过资料分析,认为子宫内膜异位症发病率的上升与人工流产的广泛施行有一定关系,此外,还与宫腔操作史等有关.说明医源性子宫内膜异位症是重要因素之一,应引起重视。在治疗上手术可做为主要的治疗措施,根据患者的病变轻重,年龄及对生育的要求采取不同的手术方式,术后给予一定时间的药物治疗,以减少复发。 相似文献
2.
目的:探讨子宫内膜结核与不孕症的关系。方法:对6年来两院诊断子宫内膜结核的13例病人进行临床及病理分析。结果:13例均为原发性不孕症患者,因临床症状不典型而常被忽略,对伴有月经异常的病人应考虑做宫腔镜检查及子宫内膜病理检查,以明确诊断及时治疗。结论:子宫内膜结核是女性生殖器结核中的主要部位之一,应该引起足够重视。 相似文献
3.
陈晓珍 《孝感职业技术学院学报》2001,(2):62-63
子宫内膜异位症是指具有生长功能的子宫内膜生长在子宫腔以外的其它部位.该病在过去属于少见病,且由于其临床表现并不具有特异性,又没有较好的确诊方法,故常造成误诊,常在久治不愈时才考虑到"子宫内膜异位症".又因为该病病程长,而且没有很好的治疗方法,所以常给患者带来极大的痛苦.70年代以来,随着腹腔镜的问世与应用,该病的阳性诊断率明显提高,使该病的发病率也不断升高,成为常见病.经过调查统计,绝大多数的患者,发病与妇科宫腔手术操作有关,因此,医源性子宫内膜异位症的预防工作尤为重要,应引起广大医务工作者的高度重视,预防乃是降低该病发病率的主要措施. 相似文献
4.
Xin-xin XU Lian-bao CAO Zhe WANG Zhen XU Bing-qian ZHANG She-ling WU Sha-sha QI Lei YAN Zi-jiang CHEN 《Journal of Zhejiang University. Science. B》2018,(5)
目的:目前宫腔粘连(Intrauterine adhesion,IUA)发病机制及治疗方法仍未明确和统一,建立一个稳定有效的宫腔粘连动物模型是开展相关研究的前提和基础。本文旨在利用电热损伤法构建兔IUA模型,观察和评估该方法的建模效果。创新点:首次提出利用电热损伤法建立兔宫腔粘连模型,并得出在损伤后7~14天内建立的兔IUA模型是有效的结论。方法:将21只成年雌性新西兰大白兔一侧子宫内膜用医用多功能高频电刀电灼损伤模拟宫腔粘连形成(A组,n=21),另一侧子宫不做处理作为自身对照(B组,n=21)。分别在损伤后7、14和28天收集兔双侧子宫组织,行苏木精-伊红染色法(HE)和Masson染色观察两侧子宫内膜病理改变,并对两侧子宫内膜的腺体个数和内膜纤维化面积比进行统计学分析和比较。另外,将损伤后7天的雌兔与成年雄兔合笼,14天后观察比较两侧子宫胚胎个数。结论:病理组织学观察显示,损伤后7和14天,A组子宫内膜腺体数量较B组减少,差异均有统计学意义(P0.05);而损伤后30天,A组子宫内膜腺体数量与B组相比差异无统计学意义。损伤后7天,A组内膜纤维化面积较B组增大,差异有统计学意义(P0.01);A组子宫胚胎个数较B组减少,差异有统计学意义(P0.01)。综上所述,采用电热损伤法建立的兔宫腔粘连模型在损伤后7~14天是稳定有效的。 相似文献
5.
目的：运用经阴道彩色多普勒超声,准确有效地诊断及鉴别诊断子宫内膜良性病变。方法：应用LIGIQ400彩色多普勒超声仪,经阴道检查36例患者的子宫内膜厚度、形态及血流状态,并观察病变处血流阻力指数。结果：有效地诊断及鉴别诊断宫颈内膜息肉、黏膜下小肌瘤、内膜增生过长。结论：经阴道彩色多普勒所提供的二维及血流信息能较为准确地诊断子宫内膜良性病变。 相似文献
6.
采用免疫组化SP法检测Livin和Fhit在30例正常子宫内膜和70例子宫内膜癌组织中的表达,研究凋亡抑制蛋白Livin和Fhit在子宫内膜癌中的表达和意义。结果显示Livin蛋白在正常子宫内膜组织中表达明显低于子宫内膜癌组织(P<0.05);Fhit蛋白在正常子宫内膜组织中表达明显高于子宫内膜癌组织(P<0.05);在子宫内膜癌组织中,随组织学分级和病理分期的增加,Livin蛋白表达阳性率逐渐上升,Fhit蛋白表达阳性率逐渐下降,而且Fhit蛋白表达与淋巴结转移相关(P<0.05);Livin蛋白和Fhit蛋白表达呈负相关(P<0.05)。结果提示Livin和Fhit异常表达可能与子宫内膜癌的发生、发展关系密切,联合检测Livin和Fhit有助于子宫内膜癌早期诊断、治疗及预后判断。 相似文献
7.
《赤峰学院学报(自然科学版)》2008,(12)
宫内节育器(IUD)是目前我国应用最广泛的避孕工具之一.但由于其在宫腔内位置的异常等原因引起带器妊娠、疼痛、出血等并发症的也比较多见.B型超声能准确可靠的判定IUD在宫腔内正常和异常的位置,是目前最为理想的监测手段. 相似文献
8.
《赤峰学院学报(自然科学版)》2016,(9)
目的:探讨瘢痕子宫胎盘植入的产前超声声像图特征,以提高产前超声检查瘢痕子宫胎盘植入的准确率.方法:回顾性分析2011-2015年在我院经产后病理或临床证实为瘢痕子宫胎盘植入的32例患者超声资料,利用二维超声观察胎盘的着床位置,与宫颈内口关系、大小、内部回声,胎盘与肌壁间关系及彩色多普勒超声检查等特点进行综合分析.结果:32例经手术及病理证实的瘢痕子宫前置胎盘植入的孕妇中,产前彩超诊断为29例,漏诊为3例,准确率90.6%(29/32).结论:准确掌握瘢痕子宫胎盘植入的产前超声声像图特点,能提高胎盘植入的检出率,对提高孕妇产前风险评估及正确处理具有重要的意义.运用超声诊断瘢痕子宫合并胎盘植入的临床特异性与灵敏度较高,效果较好,值得临床推广. 相似文献
9.
目的:检测子宫内膜异位症患者手术前后外周血T淋巴细胞亚群变化,了解病人细胞免疫功能状况。方法:采用间接免疫荧光法检测子宫内膜异位症患者体内CD3~ 、CD4~ 、CD8~ 细胞水平,并取同龄正常妇女作为对照。结果:(1)手术前与正常妇女相比,子宫内膜异位症患者体内存在CD8~ 细胞比例升高,CD4~ 细胞比例和CD4~ /CD8~ 比值下降;(2)手术后病人CD8~ 细胞逐渐回降,而CD4~ 细胞和CD4~ /CD8~ 比值呈现回升趋势。结论:子宫内膜异位症患者存在T细胞免疫异常,这种异常可在手术治疗后得以恢复。 相似文献
10.
异常子宫出血1531例病理诊断分析 总被引：2，自引：0，他引：2
目的:探讨女性异常子宫出血的主要原因及临床病理诊断价值。方法:对1531例异常子宫出血病例进行回顾性临床与病理分析。结果:基本正常内膜占63.68%,功能性子宫出血占20.31%,器质性出血占16%。年轻患者妊娠性疾病为出血主要原因。结论:对于异常子宫出血,应将诊刮、病理检查、B超和HCG检测做为常规手段进行全面检查,在此基础上内膜诊断性刮宫及子宫内膜组织病理检查是诊断异常子宫出血原因的重要手段。 相似文献
11.
Milhan D 《The International journal of childbirth education : the official publication of the International Childbirth Education Association》1992,7(4):21-28
From the 1940s to the early 1970s, diethylstilbestrol (DES), an oral, nonsteroidal synthetic estrogen, was prescribed by physicians to 2-6 million women in the US alone to prevent miscarriages. In 1970, and article documented the correlation between in utero DES exposure and development of a rare vaginal cancer, clear-cell adenocarcinoma. In 1971, US Federal Drug Administration banned the drug from use during pregnancy. Since then, controlled studies have proven that administration of DES was associated with increased spontaneous abortions, premature delivery, complications during delivery, and neonatal deaths. DES-exposed daughters in reproductive age faced increased rates of infertility, spontaneous abortion, ectopic pregnancy, and premature delivery. DES-exposed daughters may suffer more pelvic inflammatory disease and dysmenorrhea. A 1988 study related the infertility experience of 796 daughters born to mothers who took part in a double-blind, controlled study of DES use during pregnancy at a Chicago hospital in 1951 and 1952. In early 1986, primary infertility was reported by 33% of the DES-exposed daughters as opposed to 14% of the unexposed subjects. However, 81% of pregnant DES daughters have at least one full-term live birth. Uterine abnormalities including a T-shaped or hypoplastic cavity, a septate uterus, intrauterine adhesions, or irregular uterine margins were documented in 46% of the DES-exposed daughters with primary infertility. Vaginal adenosis is reported to occur in 30%-90% of DES-exposed daughters. Cervical hypoplasia and shortened cervical structure are the primary cervical abnormalities. In addition, for 10 years researchers have observed certain alterations in the immune systems of DES-exposed women. Most physicians recommend alternative birth control methods to oral contraceptives to avoid an additional exposure to synthetic estrogens. 相似文献
12.
陈江平 《河北北方学院学报(医学版)》2004,21(1):14-15
目的:探讨预防和减少产后出血的有效方法.方法:采用回顾性分析方法对5年间易引起产后出血的病例进行分析和总结.结果:宫腔填塞术的实施使产后出血率降低至4.6%.无一例切除子宫.结论:宫腔填塞在预防产后出血中有重要的临床意义. 相似文献
13.
目的：综述HSP47在纤维化疾病中的意义,探索宫腔粘连的发病机制。方法：对HSP47在肝纤维化、肺纤维化、肾纤维化、皮肤瘢痕等纤维化疾病中的意义进行探讨,探索其与宫腔粘连的关系。结果：HSP47在纤维化疾病中高表达,与宫腔粘连的发生存在某种关系。结论：对宫腔粘连的发病机制进行探讨和展望。 相似文献
14.
剖宫产切口瘢痕妊娠的早期诊断及处理 总被引：3，自引：0，他引：3
刘晨 《河北北方学院学报(医学版)》2006,23(3):19-21
目的：探讨剖宫产切口瘢痕妊娠（CSP）的早期诊断及子宫动脉栓塞术在CSP治疗中的应用。方法：分析我院4例CSP的临床表现及诊治经过。结果：4例患者均有剖宫产史，经反复B超和彩色超声确诊CSP，均行子宫动脉栓塞术一次成功。结论：彩色多普勒及B超检查是诊断CSP的主要手段，对判断预后和观察治疗效果有帮助。子宫动脉栓塞术可减少剖宫产切口瘢痕妊娠手术时引起的风险及并发症，有条件的医院应将其作为首选方法。 相似文献
15.
目的探讨经腹部及经阴道彩色多普勒超声在异位妊娠诊断中的临床价值。方法经腹部及经阴道彩色多普勒超声检查160例异位妊娠患者。结果 160例宫外孕,经手术证实输卵管妊娠129例,宫颈妊娠8例,卵巢妊娠8例,均与超声诊断相符。5例超声诊断为腹腔妊娠,其中4例手术证实为卵巢妊娠,4例超声诊断为残角子宫妊娠,3例手术证实为输卵管间质部妊娠,子宫肌壁间妊娠1例,5例超声初次检查为阴性,再次复查诊断为异位妊娠,超声诊断符合率90.6%。结论经腹及经阴道彩色多普勒超声图像直观、方便、安全,可以多次复查而无创伤性,联合运用为超声诊断异位妊娠提供更多重要的参考信息。 相似文献
16.
丁久香 《襄樊职业技术学院学报》2011,10(3):33-34
目的探讨彩色多普勒超声诊断宫外孕的特征性依据,提高宫外孕诊断的准确性。方法对临床怀疑异位妊娠患者行多途径（经阴道或腹部）彩色多普勒超声探查子宫附件区域,并与血人绒毛膜促性腺激素（HCG）检查结果比较,确诊宫外孕。结果 100例疑似宫外孕患者的超声检查中,5例因附件区未见异常包块未能确定。另95例均发现附件区包块,其中包块内实质性部分可检测到滋养血流信号57例,频谱为低阻力型;伴有不同程度的盆腹腔积液54例,双侧卵巢可同时显示85例。结论对疑似早期宫外孕的患者进行二维经阴经腹彩超检查,测量包块处滋养动脉血流频谱存在,同时测定血HCG阳性,可以早期诊断宫外孕。 相似文献
17.
Bo ZHU ;Gu-feng XU ;Yi-feng LIU ;Fan QU ;Wei-miao YAO ;Yi-min ZHU ;Hui-juan GAO ;Dan ZHANG 《Journal of Zhejiang University. Science. B》2014,15(8):750-755
研究目的:报道一例不同步双侧异位妊娠,并回顾相关文献,总结规律。创新要点:第一次报道了不同步的双侧异位妊娠。研究方法:对促排卵后行宫腔内人工授精病人发生非同步双侧输卵管妊娠的病例进行报告,辅以人绒毛膜促性腺激素(hCG)值波动曲线、超声图像以及病理切片加以阐述;同时回顾2008年以来关于双侧异位妊娠的文献,并分析病例特征。重要结论:促排卵后可能会提高双侧异位妊娠风险,一侧异位妊娠发生后,需要注意对侧是否也存在异位妊娠。 相似文献
18.
Newborn behavioral effects of intrauterine alcohol exposure were examined in 417 infants given the Brazelton Neonatal Assessment Scale. In this longitudinal prospective study, maternal alcohol use was obtained by self-report during the fifth month of pregnancy. Factor analysis of the Brazelton scale yielded 6 factors that were entered into a multiple regression analysis as dependent variables. Maternal alcohol use in mid-pregnancy was significantly related to poorer habituation and increased low arousal in newborn infants, even after adjusting for smoking and caffeine use by mothers, maternal age and nutrition during pregnancy, sex and age of the infant, and obstetric medication. This study lends further support to recognition of maternal alcohol use during pregnancy as a risk factor for alterations in newborn behavior. 相似文献
19.
Xin-xin Xu Lian-bao Cao Zhe Wang Zhen Xu Bing-qian Zhang She-ling Wu Sha-sha Qi Lei Yan Zi-jiang Chen 《Journal of Zhejiang University. Science. B》2018,19(5):383-389
The pathogenesis and therapeutic treatment of intrauterine adhesions (IUAs) remain unsolved, highlighting the need for stable and effective experimental animal models. In this study, uterine electrocoagulation of twenty-one female New Zealand White rabbits was carried out to establish an IUA model. As rabbits have two completely separate uterine horns, each rabbit had its own internal control: one uterine horn was given an electrothermal injury (Group A, n=21), and the contralateral uterine horn received no treatment and served as the control (Group B, n=21). The endometrial morphology, number of endometrial glands, area of endometrial fibrosis, and number of implanted fetuses were compared between the two groups. In Group A, the numbers of endometrial glands on Days 7 and 14 and the number of implanted fetuses were significantly lower than those in Group B (P<0.05, P<0.05, and P<0.01, respectively), while the ratio of the area with endometrial stromal fibrosis to the total endometrial area was significantly increased (P<0.01). These results suggest that this method of electrothermal injury is effective for the establishment of a rabbit IUA model between 7 and 14 d after surgery. 相似文献
20.
Maternal smoking during pregnancy retards fetal growth and depresses infant birth weight. The magnitude of these effects may be moderated by fetal genotype. The current study investigated maternal smoking, fetal genotype, and fetal growth in a large population sample of dizygotic twins. Maternal smoking retarded fetal growth in a dose-dependent fashion. In a subsample of 497 twin pairs whose mothers smoked during pregnancy, a functional polymorphism in the NAD(P)H:quinone oxidoreductase gene ( NQO1 Pro187Ser; rs1800566) was significantly associated with fetal growth within families. The effect was strongest among moderate smokers. This is the first demonstration that fetal genotype for an enzyme involved in tobacco smoke metabolism influences intrauterine growth independent of maternal genotype. Future studies should conduct formal tests of Fetal Genotype × Maternal Smoking interactions. 相似文献