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1.
OBJECTIVES: To assess the performance of published search filters in finding diagnostic test accuracy studies. METHODS: Diagnostic test accuracy search filters were identified by searching medline, our own files and by requesting unpublished filters from colleagues. We applied the filters to a case study review of diagnostic test accuracy studies for urinary tract infections (UTI) in young children. The included studies with records in medline formed the gold standard. The performance of the filters in finding those gold standard records was assessed. RESULTS: We identified twenty-three diagnostic test accuracy search filters for use with medline. The case study systematic review of UTI included 179 studies of diagnostic test accuracy, of which 160 were available in medline. The filters showed a wide range of sensitivities (range: 20.6% to 86.9%) and precision (range: 1% to 9.4%). CONCLUSIONS: Our results broadly support those reported in two other studies. The search filters tested do not offer an adequate trade-off between sensitivity and precision to be used to identify studies for systematic reviews. However, there are methods available to explore whether search filters are viable based on an objective statistical analysis of the text and indexing used in records.  相似文献   

2.
Background: People search medline for trials of healthcare interventions for clinical decisions, or to produce systematic reviews, practice guidelines, or technology assessments. Finding all relevant randomized controlled trials (RCTs) with little extraneous material is challenging. Objective: To provide comparative data on the operating characteristics of search filters designed to retrieve RCTs from medline . Methods: We identified 38 filters. The testing database comprises handsearching data from 161 clinical journals indexed in medline . Sensitivity, specificity and precision were calculated. Results: The number of terms and operating characteristics varied considerably. Comparing the retrieval against the single term ‘randomized controlled trials.pt.’ (sensitivity for retrieving RCTs, 93.7%), 24 of 38 filters had statistically higher sensitivity; 6 had a sensitivity of at least 99.0%. Four other filters had specificities (non retrieval of non‐RCTs) that were statistically not different or better than the single term (97.6%). Precision was poor: only two filters had precision (proportion of retrieved articles that were RCTs) statistically similar to that of the single term (56.4%)—all others were lower. Filters with more search terms often had lower specificity, especially at high sensitivities. Conclusion: Many RCT filters exist (n = 38). These comparative data can direct the choice of an RCT filter.  相似文献   

3.

Background

Degenerative cervical myelopathy (DCM) is a recently proposed umbrella term for symptomatic cervical spinal cord compression secondary to degeneration of the spine. Currently literature searching for DCM is challenged by the inconsistent uptake of the term ‘DCM’ with many overlapping keywords and numerous synonyms.

Objectives

Here, we adapt our previous Ovid medline search filter for the Ovid embase database, to support comprehensive literature searching. Both embase and medline are recommended as a minimum for systematic reviews.

Methods

References contained within embase identified in our prior study formed a ‘development gold standard’ reference database (N = 220). The search filter was adapted for embase and checked against the reference database. The filter was then validated against the ‘validation gold standard’.

Results

A direct translation was not possible, as medline indexing for DCM and the keywords search field were not available in embase . We also used the ‘focus’ function to improve precision. The resulting search filter has 100% sensitivity in testing.

Discussion and Conclusion

We have developed a validated search filter capable of retrieving DCM references in embase with high sensitivity. In the absence of consistent terminology and indexing, this will support more efficient and robust evidence synthesis in the field.  相似文献   

4.
Objective:Locating systematic reviews is essential for clinicians and researchers when creating or updating reviews and for decision-making in health care. This study aimed to develop a search filter for retrieving systematic reviews that improves upon the performance of the PubMed systematic review search filter.Methods:Search terms were identified from abstracts of reviews published in Cochrane Database of Systematic Reviews and the titles of articles indexed as systematic reviews in PubMed. Both the precision of the candidate terms and the number of systematic reviews retrieved from PubMed were evaluated after excluding the subset of articles retrieved by the PubMed systematic review filter. Terms that achieved a precision greater than 70% and relevant publication types indexed with MeSH terms were included in the filter search strategy.Results:The search strategy used in our filter added specific terms not included in PubMed''s systematic review filter and achieved a 61.3% increase in the number of retrieved articles that are potential systematic reviews. Moreover, it achieved an average precision that is likely greater than 80%.Conclusions:The developed search filter will enable users to identify more systematic reviews from PubMed than the PubMed systematic review filter with high precision.  相似文献   

5.
The performance of adverse effects search filters in MEDLINE and EMBASE   总被引:1,自引:1,他引:0  
Background: Search filters can potentially improve the efficiency of searches involving electronic databases such as medline and embase . Although search filters have been developed for identifying records that contain adverse effects data, little is known about the sensitivity of such filters. Objectives: This study measured the sensitivity of using available adverse effects filters to retrieve papers with adverse effects data. Methods: A total of 233 included studies from 26 systematic reviews of adverse effects were used for analysis. Search filters from medline and embase were tested for their sensitivity in retrieving the records included in these reviews. In addition, the sensitivity of each individual search term used in at least one search filter was measured. Results: Subheadings proved the most useful search terms in both medline and embase . No indexing terms in medline achieved over 12% sensitivity. The sensitivity of published search filters varied in medline from 3% to 93% and in embase from 57% to 97%. Whether this level of sensitivity is acceptable will be dependent on the purpose of the search. Conclusions: Although no adverse effects search filter captured all the relevant records, high sensitivity could be achieved. Search filters may therefore be useful in retrieving adverse effects data.  相似文献   

6.
Background and objective: With the advent of an interprofessional approach to delivering health care in today's health care systems, should health care professionals be educated together? Supported by policy‐making circles worldwide, interprofessional education is accumulating a research literature at an exponential rate. Using one‐word search terms in the medline query box for scoping this body of literature, we obtained an unmanageable number of articles (342 338 in all fields). The objective of our study was to outline an efficient specific query. Methods: We created 1072 phrasal search terms consisting of a prefix, an adjective and a noun. Of those, 66 were prolific for the whole indexed period (1950–2006). Results: Only 2510 citations have the search term in all medline fields; of those 2049 were in title/abstract and 652 in title alone. From the 1950s, the citations were published at a slow rate, but the rate then exploded during the decade 1995 to 2006. The combination of prefixes ‘inter’ and ‘multi’ with the adjectives ‘professional’, ‘disciplinary’ and ‘shared’, and the nouns ‘education’, ‘learning’ and ‘training’ may retrieve almost all the relevant citations, while the terms ‘collaborative’ and ‘common’ may retrieve mainly irrelevant ones. The adjective ‘cohesive’ and nouns ‘practice’ and ‘role’ should be also considered. Conclusion: Phrasal search terms highly increased the relevance of medline ‐retrieved citations.  相似文献   

7.
Objectives: National databases may be useful sources in the production of a systematic review (SR). The aim of this study was to assess the potential benefit of a systematic search in the German database ‘Current Contents Medizin’ (CCMed ). Methods: The study was conducted on the basis of published SRs that included CCMed as a literature source. Eligible SRs were identified through a systematic search in medline , embase and The Cochrane Library. The websites of German Health Technology Assessment agencies were also screened. Citations of primary studies included as relevant in the SRs were extracted and then categorised. Results: The search yielded 52 eligible SRs. A total of 1505 relevant citations were extracted. Seventy‐seven of these articles were published in journals indexed in CCMed . Thirty‐two of the 77 citations were indexed in CCMed , but only eight of the 32 were unique. Of these eight citations, seven were not identified by a systematic search, but by handsearching. Only one unique citation, an observational study, was identified in CCMed by a systematic search. Conclusions: In the production of SRs, a systematic search in CCMed identifies relevant studies only in exceptional cases. Therefore, the routine inclusion of this database in systematic searches does not appear meaningful.  相似文献   

8.
Citations selected from the bibliographies of recent texts, a specialized subject bibliography, and review articles were checked in both Cumulated Index Medicus (IM) and the Bibliography of Bioethics (BB) to compare coverage, publication delay, probable causes of indexing and retrieval failure, and the ease with which relevant citations were retrieved. The study also attempted to determine whether BB included appropriate articles from the MEDLINE database in a timely and systematic manner. While 98% of the IM citations appeared within a year of publication, 79% of the BB citations appeared two to three years after their publication dates. The average citation appeared twice as frequently in IM as in BB.  相似文献   

9.
OBJECTIVES: Difficulties encountered in the retrieval of evidence-based nursing (EBN) literature and recognition of terminology, research focus, and design differences between evidence-based medicine and nursing led to the realization that nursing needs its own filter strategies for evidence-based practice. This article describes the development and evaluation of filters that facilitate evidence-based nursing searches. METHODS: An inductive, multistep methodology was employed. A sleep search strategy was developed for uniform application to all filters for filter development and evaluation purposes. An EBN matrix was next developed as a framework to illustrate conceptually the placement of nursing-sensitive filters along two axes: horizontally, an adapted nursing process, and vertically, levels of evidence. Nursing diagnosis, patient outcomes, and primary data filters were developed recursively. Through an interface with the PubMed search engine, the EBN matrix filters were inserted into a database that executes filter searches, retrieves citations, and stores and updates retrieved citations sets hourly. For evaluation purposes, the filters were subjected to sensitivity and specificity analyses and retrieval set comparisons. Once the evaluation was complete, hyperlinks providing access to any one or a combination of completed filters to the EBN matrix were created. Subject searches on any topic may be applied to the filters, which interface with PubMed. RESULTS: Sensitivity and specificity for the combined nursing diagnosis and primary data filter were 64% and 99%, respectively; for the patient outcomes filter, the results were 75% and 71%, respectively. Comparisons were made between the EBN matrix filters (nursing diagnosis and primary data) and PubMed's Clinical Queries (diagnosis and sensitivity) filters. Additional comparisons examined publication types and indexing differences. Review articles accounted for the majority of the publication type differences, because "review" was accepted by the CQ but was "NOT'd" by the EBN filter. Indexing comparisons revealed that although the term "nursing diagnosis" is in Medical Subject Headings (MeSH), the nursing diagnoses themselves (e.g., sleep deprivation, disturbed sleep pattern) are not indexed as nursing diagnoses. As a result, abstracts deemed to be appropriate nursing diagnosis by the EBN filter were not accepted by the CQ diagnosis filter. CONCLUSIONS: The EBN filter capture of desired articles may be enhanced by further refinement to achieve a greater degree of filter sensitivity. Retrieval set comparisons revealed publication type differences and indexing issues. The EBN matrix filter "NOT'd" out "review," while the CQ filter did not. Indexing issues were identified that explained the retrieval of articles deemed appropriate by the EBN filter matrix but not included in the CQ retrieval. These results have MeSH definition and indexing implications as well as implications for clinical decision support in nursing practice.  相似文献   

10.
The amount of health information available on the Internet is considerable. In this context, several health gateways have been developed. Among them, CISMeF (Catalogue and Index of Health Resources in French) was designed to catalogue and index health resources in French. The goal of this article is to describe the various enhancements to the MeSH thesaurus developed by the CISMeF team to adapt this terminology to the broader field of health Internet resources instead of scientific articles for the medline bibliographic database. CISMeF uses two standard tools for organizing information: the MeSH thesaurus and several metadata element sets, in particular the Dublin Core metadata format. The heterogeneity of Internet health resources led the CISMeF team to enhance the MeSH thesaurus with the introduction of two new concepts, respectively, resource types and metaterms. CISMeF resource types are a generalization of the publication types of medline. A resource type describes the nature of the resource and MeSH keyword/qualifier pairs describe the subject of the resource. A metaterm is generally a medical specialty or a biological science, which has semantic links with one or more MeSH keywords, qualifiers and resource types. The CISMeF terminology is exploited for several tasks: resource indexing performed manually, resource categorization performed automatically, visualization and navigation through the concept hierarchies and information retrieval using the Doc'CISMeF search engine. The CISMeF health gateway uses several MeSH thesaurus enhancements to optimize information retrieval, hierarchy navigation and automatic indexing.  相似文献   

11.
Background:Systematic reviews are comprehensive, robust, inclusive, transparent, and reproducible when bringing together the evidence to answer a research question. Various guidelines provide recommendations on the expertise required to conduct a systematic review, where and how to search for literature, and what should be reported in the published review. However, the finer details of the search results are not typically reported to allow the search methods or search efficiency to be evaluated.Case Presentation:This case study presents a search summary table, containing the details of which databases were searched, which supplementary search methods were used, and where the included articles were found. It was developed and published alongside a recent systematic review. This simple format can be used in future systematic reviews to improve search results reporting.Conclusions:Publishing a search summary table in all systematic reviews would add to the growing evidence base about information retrieval, which would help in determining which databases to search for which type of review (in terms of either topic or scope), what supplementary search methods are most effective, what type of literature is being included, and where it is found. It would also provide evidence for future searching and search methods research.  相似文献   

12.
Background: Romania is a low‐income country of 22 million people and, currently, information regarding mental health research is limited. Romania is one of the last countries in eastern Europe not to have its own bibliographic biomedical database. Aim: To assess the content and quality of Romanian psychiatric research activity over time. Method: embase (1980 to April 2008), medline (1950 to April 2008) and Psyc INFO (1806 to April 2008) were systematically searched for psychiatric articles originating from Romania. The sample from Psyc INFO was described. Results: Psyc INFO was by far the best source of Romanian mental health literature with a considerable increase in the publication activity since 2000 (Psyc INFO identified 3236 hits, medline 549, embase 139). Most papers are in English, but a sizeable minority are in Romanian (30%), French (4%) or Hungarian (4%). The main topics of interest are cognitive processes, creativity, schizophrenia and cognitive development and stress and are, according to Psyc INFO’s indexing, ‘empirical studies’. Seventeen randomised trials were identified with all studies after 2000 being sponsored by industry. Conclusions: Surprisingly, and not in keeping with other studies of the literature of neighbouring countries, Psyc INFO is the major source of psychiatric bibliographic records of this region. There are signs of a resurgence of research activity in Romania and as the number of local mental health workers increases we can expect more output. Industry is now funding evaluative studies in Romania. As everywhere, but perhaps more acutely in situations of severely limited research support, there is a difficult balance to be struck between benefiting support and losing independence.  相似文献   

13.
Objectives: To devise and evaluate a sensitive search strategy to retrieve diagnostic studies on specific diagnostic tests for deep vein thrombosis (DVT). Methods: Systematic reviews on diagnostic tests for DVT were identified and the studies cited by them used to produce a reference set of search results (to be used to evaluate different search strategies). Five existing diagnosis search filters were combined to produce a sensitive search. This combined search was then refined to produce a more specific strategy, which was run on medline and the results were checked against the reference set. This search was too specific and was modified to produce a more balanced final strategy, which was again tested and the results compared with the reference set. The sensitivity of this newly created strategy was compared with the existing diagnosis searches already found. Finally, studies identified by the final search strategy were critically appraised for validity and relevance and the selected articles were compared with those found in the reference set. Results: The final filter retrieved 124 out of 126 references from the reference set. From the search result, 227 cohort studies were selected and 147 of these were not cited in any of the systematic reviews on diagnostic tests for DVT. Conclusions: The search strategy had 98.8% sensitivity. The precision of 8.8%, although low, compares well with other strategies with high sensitivity. Most of the systematic reviews on diagnosing a DVT have omitted a number of high quality articles.  相似文献   

14.

Background

The most current objectively derived search filters for adverse drug effects are 15 years old and other strategies have not been developed and tested empirically.

Objective

To develop and validate search filters to retrieve evidence on adverse drug effects from Ovid medline and Ovid Embase.

Methods

We identified systematic reviews of adverse drug effects in Epistemonikos. From these reviews, we collated their included studies which we then randomly divided into three tests and one validation set of records. We constructed a search strategy to maximise relative recall using word frequency analysis with test set one. This search strategy was then refined using test sets two and three and validated on the final set of records.

Results

Of 107 systematic reviews which met our inclusion criteria, 1948 unique included studies were available from medline and 1980 from Embase. Generic adverse drug effects searches in medline and Embase achieved 90% and 89% relative recall, respectively. When specific adverse effects terms were added recall was improved.

Conclusion

We have derived and validated search filters that retrieve around 90% of records with adverse drug effects data in medline and Embase. The addition of specific adverse effects terms is required to achieve higher recall.  相似文献   

15.
16.
Clinical medical journals have not been effective in meeting the information needs of practitioners and bridging the gap between clinical research and practice. The slow adoption of results of clinical research is at least partly due to the failure of clinical journals to disseminate information in a way that would motivate practitioners to change practice. Although implementation is primarily a local process, medical journals are in a unique position to advance implementation by modifying their focus and adjusting their contents. Strategies that may be useful include publication of pre‐appraised evidence summaries and ‘clinical bottom‐lines’ and giving importance to systematic reviews and large evaluative research articles as they represent higher levels of evidence and have greater potential to change practice. Clinical journals should encourage researchers to consider how and by whom the findings will be used and provide information on implications for implementation such as possible strategies that may work, cost‐effectiveness, side‐effects and potential barriers to implementation. Medical journal publishers should explore ways to cooperate so that findings of landmark clinical trials could be shared thus reducing the ‘scatter’ of medical information. Electronic media offers numerous advantages such as quick accessibility and linking of information, and medical journals should capitalize on such innovations. There is a paradigm shift in health care practice as evidence is consciously and explicitly incorporated into individual patient care. Medical journals need to change to reflect this change in practice and provide practitioners with valid and relevant information.  相似文献   

17.
BACKGROUND: There is a small body of research on improving the clarity of abstracts in general that is relevant to improving the clarity of abstracts of systematic reviews. OBJECTIVES: To summarize this earlier research and indicate its implications for writing the abstracts of systematic reviews. METHOD: Literature review with commentary on three main features affecting the clarity of abstracts: their language, structure, and typographical presentation. CONCLUSIONS: The abstracts of systematic reviews should be easier to read than the abstracts of medical research articles, as they are targeted at a wider audience. The aims, methods, results, and conclusions of systematic reviews need to be presented in a consistent way to help search and retrieval. The typographic detailing of the abstracts (type-sizes, spacing, and weights) should be planned to help, rather than confuse, the reader.  相似文献   

18.
Introduction: Locating reports of trials from journals not indexed in the major databases presents difficulties to systematic reviewers, and may be a factor in improving the reliability of the reviews. Objectives: To identify and make available reports of controlled trials from the Australasian Medical Index (AMI). To measure the quality of indexing of trials in AMI. Methods: Using a highly sensitive search strategy consisting of methodology indexing and free‐text terms, records from AMI were read for reports of controlled trials. Trials meeting the criteria were submitted for inclusion in The Cochrane Controlled Trials Register (CCTR) and assessed for the quality of their indexing. Results: 3621 records were downloaded, of which 512 were identified as reports of controlled trials (317 RCTs; 195 CCTs) and submitted to CCTR. The precision of methodology indexing terms was 60%, but sensitivity just 18%. The quality of indexing of trials was generally poor with only 50 tagged with the RCT/CCT publication type term. 453 reports (88%) were not previously available in CCTR. Conclusions: The large proportion of trials found to be unique to the AMI database increases the pool of studies available to systematic reviewers, and helps ensure CCTR remains the most comprehensive source of trials.  相似文献   

19.

Background

Search filter development for adverse effects has tended to focus on retrieving studies of drug interventions. However, a different approach is required for surgical interventions.

Objective

To develop and validate search filters for medline and Embase for the adverse effects of surgical interventions.

Methods

Systematic reviews of surgical interventions where the primary focus was to evaluate adverse effect(s) were sought. The included studies within these reviews were divided randomly into a development set, evaluation set and validation set. Using word frequency analysis we constructed a sensitivity maximising search strategy and this was tested in the evaluation and validation set.

Results

Three hundred and fifty eight papers were included from 19 surgical intervention reviews. Three hundred and fifty two papers were available on medline and 348 were available on Embase. Generic adverse effects search strategies in medline and Embase could achieve approximately 90% relative recall. Recall could be further improved with the addition of specific adverse effects terms to the search strategies.

Conclusion

We have derived and validated a novel search filter that has reasonable performance for identifying adverse effects of surgical interventions in medline and Embase. However, we appreciate the limitations of our methods, and recommend further research on larger sample sizes and prospective systematic reviews.  相似文献   

20.
The librarian's roles in the systematic review process: a case study.   总被引:3,自引:0,他引:3  
QUESTION/SETTING: Although the systematic review has become a research standard, little information addresses the actions of the librarian on a systematic review team. METHOD: This article is an observational case study that chronicles a librarian's required involvement, skills, and responsibilities in each stage of a real-life systematic review. MAIN RESULTS: Examining the review process reveals that the librarian's multiple roles as an expert searcher, organizer, and analyzer form an integral part of the Cochrane Collaboration's criteria for conducting systematic reviews. Moreover, the responsibilities of the expert searcher directly reflect the key skills and knowledge depicted in the "Definition of Expert Searching" section of the Medical Library Association's policy statement, "Role of Expert Searching in Health Sciences Libraries." CONCLUSION: Although the librarian's multiple roles are important in all forms of medical research, they are crucial in a systematic review. As an expert searcher, the librarian must interact with the investigators to develop the terms required for a comprehensive search strategy in multiple appropriate sources. As an organizer and analyzer, the librarian must effectively manage the articles and document the search, retrieval, and archival processes.  相似文献   

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