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1.
A novel artificial anal sphincter system has been developed to simulate the normal physiology of the human anorectum. With the goal of engineering a safe and reliable device, the model of human colonic blood flow has been built and the relationship between the colonic blood flow rate and the operating occlusion pressure of the anorectum is achieved. The tissue ischemia is analyzed based on constitutive relations for human anorectum. The results suggest that at the planned operating occlusion pressure of less than 4 kPa the artificial anal sphincter should not risk the vaseularity of the human colon.  相似文献   

2.
Boron-doped diamond (BDD) film electrodes using Ta as substrates were employed for anodic oxidation of salicylic acid (SA). The effects of operational variables including initial concentration, current density, temperature and pH were examined. The results showed that BDD films deposited on the Ta substrates had high electrocatalytic activity for SA degradation. There was little effect ofpH on SA degradation. The current efficiency (CE) ,aas fbund to be dependent mainly on the initial SA concentration, current density and temperature. Chemical oxygen demand (COD) was reduced from 830 mg/L to 42 mg/L under a current density of200A/m^2 at 30℃.  相似文献   

3.
Molecular dynamics simulation was carried out to study the behavior of liquid 1,2-dichloroethane molecules under external electric fields including direct current field, alternating current field and positive-half-period cosin field. The maximum applied field strength was 108 V/m, the maximum frequency of the alternating current field and that of the positive-half-period cosine field was 1012 Hz. The simulation revealed that the field type and field strength act on the population of the molecular configuration. In the strong direct current field, all trans forms converted completely into gauche forms. Order parameter and the correlation of the system torsion angle were also investigated. The results suggested that these two dynamical parameters depended also on the field type and the field strength. The maximum of order parameter was found to be at 0.6 in the strong direct current field.  相似文献   

4.
A differential cross-coupled regulated cascode(RGC)transimpedance amplifier(TIA)is proposed. The theory of multi-stage common-source(CS) configuration as an auxiliary amplifier to enhance the bandwidth and output impedance of RGC topology is analyzed. Additionally, negative Miller capacitance and shunt active inductor compensation are exploited to further expand the bandwidth. The proposed RGC TIA is simulated based on UMC 0.18 μm standard CMOS process. The simulation results demonstrate that the proposed TIA has a high transimpedance of 60.5 d B?, and a-3 d B bandwidth of 5.4 GHz is achieved for 0.5 p F input capacitance. The average equivalent input noise current spectral density is about 20 p A/Hz~(1/2) in the interested frequency, and the TIA consumes 20 m W DC power under 1.8 V supply voltage. The voltage swing is 460 m V pp, and the saturation input current is 500 μA.  相似文献   

5.
Modified 1-ethyl-3-(3-dimethylaminopropy) carbodiimide (EDC) method was employed to synthesize the artificial antigen of enrofloxacin (ENR), and New Zealand rabbits were used to produce anti-ENR polyclonal antibody (pAb). Based on the checkerboard titration, an indirect competitive enzyme-linked immunosorbent assay (ELISA) standard curve was established. This assay was sensitive and had a linear range from 0.6 to 148.0 μg/kg (R 2=0.9567), with the half maximal inhibitory concentration (IC50) and limit of detection (LOD) values of 9.4 μg/kg and 0.2 μg/kg, respectively. Of all the competitive analogues, the produced pAb exhibited a high cross-reactivity to ciprofloxacin (CIP) (87%), the main metabolite of ENR in tissues. After optimization, the matrix effects can be ignored using a 10-fold dilution in beef and 20-fold dilution in pork. The overall recoveries and coefficients of variation (CVs) were in the ranges of 86%–109% and 6.8%–13.1%, respectively. It can be concluded that the established ELISA method is suitable for simultaneous detection of ENR and CIP in animal tissues.  相似文献   

6.
To investigate the influence of microwave radiation on the human fibroblast nuclei, the effects of three variants of electromagnetic wave polarization, linear and left-handed and right-handed elliptically polarized, were examined. Experimental conditions were: frequency (f) 36.65 GHz, power density (P) at the surface of exposed object 1, 10, 30, and 100 μW/cm2, exposure time 10 s. Human fibroblasts growing in a monolayer on a cover slide were exposed to microwave electromagnetic radiation. The layer of medium that covered cells during microwave exposure was about 1 mm thick. Cells were stained immediately after irradiation by 2% (w/v) orcein solution in 45% (w/v) acetic acid. Experiments were made at room temperature (25 °C), and control cell samples were processed in the same conditions. We assessed heterochromatin granule quantity (HGQ) at 600× magnification. Microwave irradiation at the intensity of 1 μW/cm2 produced no effect, and irradiation at the intensities of 10 and 100 μW/cm2 induced an increase in HGQ. More intense irradiation induced more chromatin condensation. The right-handed elliptically polarized radiation revealed more biological activity than the left-handed polarized one.  相似文献   

7.
在分析机载SAR回波信号模型的基础上 ,提出了一种生成SAR图像回波数据的方法 ,并对三维人造目标进行了成像仿真 ,验证了这种方法的正确性和可行性 ,从中得出了一些有意义的结论  相似文献   

8.
INTRODUCTION With the development of modern electronics,there is a growing trend of designing a low-voltagehigh precision current reference in many mixed-signaland analog circuits such as data converters (Mehr andSinger, 2000; Oh et al., 2004), oscillators and PLLs(Razavi, 2001; Banba and Shiga, 1999). Low-costreasons need the reference to be realized in simplestandard CMOS logic process technology, withoutresorting to the use of BiCMOS process and specialdevices such as floating-g…  相似文献   

9.
外电场作用下柔性模型水的分子动力学模拟   总被引:1,自引:0,他引:1  
1 Introduction Water is the most common liquid in nature and it isalso i mportant in numerous chemical and biologicalprogresses . With the availability of computers , MonteCarlo (MC) and molecular dynamics (MD) si mulationshave beenintroduced and efforts have been devoted toexamining the microscopic structure and dynamicproperties of liquid water utilizing computer si mula-tions[1-8].It is known that liquid water is totally con-nected by random tetrahedral hydrogen-bonds net- work[1 ,2]. Ho…  相似文献   

10.
合成孔径雷达图像中相干斑噪声的存在降低了图像的质量,影响了图像的解译和后续处理。分析了图像相干斑噪声产生的机理,介绍了基于空域和频域的滤波方法的研究现状,并在阐述小波阈值去噪声方法的基础上考虑根据小波系数子带分布特征用定向窗口中值滤波代替阈值去噪声,提出了结合中值滤波的小波域SAR相干斑抑制方法,并通过和已有的方法比较,说明该方法非常有效。  相似文献   

11.
Ba0.6Sr0.4TiO3 (BST) thin films with and without HfO 2 buffer layer were fabricated on Pt/Ti/SiO2/Si substrates by pulsed laser deposition. Dependences of HfO 2 thickness on the dielectric property and leakage current of BST thin films were focused. The dielectric constant of BST thin films increased and then decreased with the increase of HfO 2 thickness, while the dielectric relaxation was gradually improved. The loss tangent and leakage current under positive bias decreased with the HfO 2 thickness increasing. The leakage current analysis based on the Schottky emission indicated an improvement of the BST/Pt interface with HfO 2 buffer layer. The loss tangent, tunability and figure of merit of optimized HfO 2 buffered BST thin film achieved 0.009 8, 21.91% (E max = 200 kV/cm), 22.40 at 10 6 Hz, respectively.  相似文献   

12.
The propulsive efficiency of a plunging NACA0012 airfoil is maximized by means of a simple numerical optimization method based on the response surface methodology (RSM). The control parameters are the amplitude and the reduced frequency of the harmonic sinusoidal motion. The 2D unsteady laminar flow around the plunging airfoil is computed by solving the Navier-Stokes equations for three Reynolds number values (Re = 3.3×103, 1.1×104, and 2.2×104). The Nelder-Mead algorithm is used to find the best control parameters leading to the optimal propulsive efficiency over the constructed response surfaces. It is found that, for a given efficiency level and regardless of the considered Re value, it is possible either to obtain high thrust by selecting a high oscillation frequency or to reduce the input power by adopting a low plunging amplitude.  相似文献   

13.
In this column, the author summarizes four research studies that further support the benefits of normal birth. The topics of the studies include the optimality of midwifery care for pregnant women at moderate risk; obstetric care practices associated with anal sphincter tears in vaginal births; the effect of acupuncture treatment on women with prelabor rupture of membranes at term; and women's ability to adapt to early labor.  相似文献   

14.
Ultra high toughness cementitious composite (UHTCC) usually shows strain hardening and multiple cracking under static tension loads. In practice, structures could be exposed to high strain rates during an earthquake. Whether UHTCC can maintain its unique properties and provide high structural performance under seismic loading rates largely determines whether it can successfully fulfil its intended function. To determine the rate dependence of UHTCC, uniaxial tensile tests with strain rates ranging from 4×10?6 s?1 to 1×10?1 s?1 were conducted with thin plates. The experimental results showed that UHTCC had significant strain hardening and excellent multiple cracking properties under all the rates tested. The ultimate tensile strain lay in the range of 3.7% to 4.1% and was almost immune to the change in strain rates. The rate of 1×10?3 s?1 seemed to be a threshold for dynamic increase effects of the first crack tensile strength, elastic modulus, ultimate tensile strength, and energy absorption capability. When the strain rate was higher than the threshold, the dynamic increase effects became more pronounced. The energy absorption capability was much higher than that of concrete, and the average ultimate crack widths were controlled below 0.1 mm under all rates. Several fitting formulas were obtained based on the experimental results.  相似文献   

15.
Objective: To study the effect of levobupivacaine and bupivacaine on the contractility of isolated uterine muscle strips from pregnant and non-pregnant female rats. Methods: Full-thick myometrial strips were prepared from 18- to 2 l-day pregnant (n=8) and non-pregnant rats (n=7). After contractions became regular, strips were exposed to cumulative concentrations of the two drugs from 10^-8 to 10^-4 mol/L, amplitude and frequency of the uterine contraction was recorded. Results: Two local anesthetics caused a concentration dependent inhibition on contractility of myometrial strips from pregnant and non-pregnant rats. In the myometrium from non-pregnant rats, -log/C50 of levobupivacaine and bupivacaine were 4.85 and 4.25 respectively. In the myometrium from pregnant rats, similar concentrations of levobupivacaine and bupivacaine were observed, -log/C50 were 2.7 and 2.9 respectively. Levobupivacaine produced an increase in amplitude of contractions, while bupivacaine showed an increased trend in frequency. Conclusion: These results demonstrate that levobupivacaine and bupivacaine may inhibit myometrium contractility. The inhibitory effect of levobupivacaine or bupivacaine is not enhanced by gestation in rat. Levobupivacaine may have more positive influence than bupivacaine in pregnant myometrium.  相似文献   

16.
Mutation breeding is based on the induction of genetic variations; hence knowledge of the frequency and type of induced mutations is of paramount importance for the design and implementation of a mutation breeding program. Although γ ray irradiation has been widely used since the 1960s in the breeding of about 200 economically important plant species, molecular elucidation of its genetic effects has so far been achieved largely by analysis of target genes or genomic regions. In the present study, the whole genomes of six γ-irradiated M2 rice plants were sequenced; a total of 144–188 million high-quality (Q>20) reads were generated for each M2 plant, resulting in genome coverage of >45 times for each plant. Single base substitution (SBS) and short insertion/deletion (Indel) mutations were detected at the average frequency of 7.5×10?6–9.8×10?6 in the six M2 rice plants (SBS being about 4 times more frequent than Indels). Structural and copy number variations, though less frequent than SBS and Indel, were also identified and validated. The mutations were scattered in all genomic regions across 12 rice chromosomes without apparent hotspots. The present study is the first genome-wide single-nucleotide resolution study on the feature and frequency of γ irradiation-induced mutations in a seed propagated crop; the findings are of practical importance for mutation breeding of rice and other crop species.  相似文献   

17.
Antenna is very crucial to radiotelemetry capsules which can measure the physiological parameters of the gastroin- testinal (GI) tract. The objective of this paper is to design a novel spiral slots microstrip patch antenna for the radiotelemetry capsules communicating with external recorder at 915 MHz located in ISM (Industry, Science, and Medical) bands. The microstrip patch antenna is designed and evaluated using the finite-difference time-domain (FDTD) method. Return loss characteristics and the effect of the human body on resonant frequency are analyzed, and the performances of radiation patterns at different positions of the human alimentary tract are also estimated. Finally, specific absorption rate (SAR) computations are performed, and the peak 1-g and 10-g SAR values are calculated. According to the peak SAR values, the maximum delivered power for the designed antenna was found so that the SAR values of the antenna satisfy the ANSI (American National Standards Institute) limitations.  相似文献   

18.

The metal oxide/nitrogen-doped carbon (NC) compounds zirconium oxide/NC (ZrO2/NC) and cerium oxide/NC (CeO2/NC) were synthesized via the pyrolysis of polyaniline on the metal oxide surface. The characterization of the ZrO2/NC and CeO2/NC catalysts showed more active CO2 reduction reaction activity than that of NC catalyst without metal oxide. Gas chromatography analysis revealed that CO and H2 were the primary products, and no liquid-phase products were detected via proton nuclear magnetic resonance spectroscopy or high-performance liquid chromatography. The maximum Faraday efficiency of ZrO2/NC reached 90% at − 0.73 V (vs. RHE), with the current density of CO at 5.5 mA/cm2; this Faraday efficiency value was higher than that of NC (41%), with the current density of CO at 3.1 mA/cm2. The interaction between the metal oxide and carbon allowed the efficient formation of defect sites, especially imine-type nitrogen, strengthening the adsorption of the key reaction intermediate CO2•− and thus promoting the CO2 reduction reaction.

  相似文献   

19.
以550 kV三相GIS母线为例,利用ANSYS有限元仿真软件建立母线实体模型,在电磁学、导热学的基础上对模型进行电磁场、温度场分析和仿真。仿真结果表明,550 kV三相GIS母线在工频电压下的电流密度具有明显的集肤效应,温度分布与电流密度分布一致,在此基础上对母线的外壳厚度及截面积进行了优化设计。  相似文献   

20.
Leakage currents, tiny currents flowing from an everyday-life appliance through the body to the ground, can cause a non-adequate perception (called electrocutaneous sensation, ECS) or even pain and should be avoided. Safety standards for low-frequency range are based on experimental results of current thresholds of electrocutaneous sensations, which however show a wide range between about 50 pA (rms) and 1000 μA (rms). In order to be able to explain these differences, the perception threshold was measured repeatedly in experiments with test persons under identical experimental setup, but by means of different methods (measuring strategies), namely: direct adjustment, classical threshold as amperage of 50% perception probability, and confidence rating procedure of signal detection theory. The current is injected using a I cm2 electrode at the highly touch sensitive part of the index fingertip. These investigations show for the first time that the threshold of electrocutaneous sensations is influenced both by adaptation to the non-adequate stimulus and individual, emotional factors. Theretbre, classical methods, on which the majority of the safety investigations are based, cannot be used to determine a leakage current threshold. The confidence rating procedure of the modem signal detection theory yields a value of 179.5 μA (rms) at 50 Hz power supply net frequency as the lower end of the 95% confidence range considering the variance in the investigated group. This value is expected to be free of adaptation influences, and is distinctly lower than the European limits and supports the stricter regulations of Canada and USA.  相似文献   

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