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1.
The aim of the study was to compare the effect of resistance training (RT) frequencies of five times (RT5), thrice- (RT3) or twice- (RT2) weekly in muscle strength and hypertrophy in young men. Were used a within-subjects design in which 20 participants had one leg randomly assigned to RT5 and the other to RT3 or to RT2. 1?RM and muscle cross-sectional area (CSA) were assessed at baseline, after four (W4) and eight (W8) RT weeks. RT5 resulted in greater total training volume (TTV) than RT3 and RT2 (P?=?.001). 1?RM increased similarly between protocols at W4 (RT5: 55?±?9?Kg, effect size (ES): 1.18; RT3: 51?±?11?Kg, ES: 0.80; RT2: 54?±?7?Kg, ES: 1.13; P?P?2, ES: 0.54; RT3: 22.0?±?4.6?cm2, ES: 0.19; RT2: ES: 0.25; 23.8?±?3.8?cm2; P?2; ES: 0.69; RT3: 23.6?±?4.2?cm2, ES: 0.58; RT2: 25.5?±?3.7?cm2; ES: 0.70; P?2; RT3: 21.2?±?4.0?cm2; RT2: 22.9?±?3.8?cm2). Performing RT5, RT3 and RT2 a week result in similar muscle strength increase and hypertrophy, despite higher TTV for RT5.  相似文献   

2.
Objective: To analyse the effect of resistance training (RT) frequency on muscle mass, appendicular lean soft tissue, insulin-like growth factor 1 (IGF-1), testosterone, and their changes with detraining in older women. Methods: Forty-five physically independent older women (≥ 60?years) were randomly assigned to perform RT either two (G2X, n = 21) or three times/week (G3X, n = 24), during 12?weeks (8 exercises, 1 set of 10–15 repetition maximum). Muscle mass and appendicular lean soft tissue, IGF-1, testosterone, and dietary intake were measured at pre-training, post-training, and after detraining (12?weeks). Results: Muscle mass and appendicular lean soft tissue significantly increased post-training (G2X?=?+5.5% and G3X?=?+5.8%, P?P?P?Conclusion: We conclude that lower RT frequency is as effective as higher frequency to improve muscle mass and appendicular lean soft tissue, and to maintain testosterone and IGF-1. Additionally, detraining may reduce testosterone regardless of RT frequency. These results are specifically for community-dwelling older women and may not be generalized to other populations.  相似文献   

3.
ABSTRACT

Purpose: Trampoline parks are becoming popular in many countries, providing recreational facilities for children and adults. This study investigated the effects of trampoline training on knee muscles strength and balance in young adults. Methods: Twenty-six participants (14 males, 12 females) were randomized into trampoline training (TT) and resistance training (RT) groups to undergo a 6-week supervised intervention program (2 × 30 min per week). TT group performed basic trampoline exercises while the RT group performed resistance training targeting lower extremities muscles. Peak knee extension and flexion torque, postural sway characteristics, and Y balance test (YBT) performance were evaluated before and after the intervention. A mixed model analysis of variance (group × time) was applied. Results: After training there were significant improvements in knee extension torque (mean differencepost-pre [95% CI], TT: 0.27 [0.00, 0.54] N?m/kg, RT: 0.31 [0.09,0.54] N?m/kg, p = .001), knee flexion torque (TT: 0.25 [0.17,0.33] N?m/kg, RT: 0.21 [0.08,0.34] N?m/kg, p < .001), and dynamic balance (YBT composite scores, mean differencepost-pre [95% CI], TT: 4.9 [?0.3, 10.2]%, RT: 5.2 [2.4,8.0]%, p = .001). No difference between groups was found. Conclusion: Trampoline training can be as effective as resistance training for improving knee muscles strength and dynamic balance in young men and women.  相似文献   

4.
We tested the hypothesis that backward downhill walking (eccentric component) impairs both voluntary activation and muscle contractile properties in the plantar flexors and delays recovery as compared to a gradient and distance-matched uphill walk. Fourteen males performed two 30-min walking exercises (velocity: 1?m/?s; grade: 25%; load: 12% of body weight), one downhill (DW) and one uphill (UP), in a counterbalanced order, separated by 6?weeks. Neuromuscular test sessions were performed before, after, 24-, 48- and 72-h post-exercise, including motor nerve stimulations during brief (5?s) and sustained (1?min) maximal isometric voluntary contractions of the plantar flexors. DW (?18.1?±?11.1%, P?P?=.15), decreased torque production during brief contractions for at least three days post-exercise (P?P?P?=?.024) and DW (?25.6?±?10.3%, P?P?=?.001) was lower in DW than UP. Peak twitch torque and maximum rates of torque development and relaxation were equally reduced after UP and DW (P?P?P?>?.05). Using a direct comparison, the capacity to drive the plantar flexors during sustained contractions remains sub-optimal during the three-day recovery period in response to non-exhaustive, downhill backward walking in reference to an uphill exercise matched for distance covered.  相似文献   

5.
Purpose:The aim of the study was to determine whether corticospinal excitability and inhibition of the tibialis anterior during single-leg standing differs among individuals with chronic ankle instability(CAI),lateral ankle sprain copers,and healthy controls.Methods:Twenty-three participants with CAI,23 lateral ankle sprain copers,and 24 healthy control participants volunteered.Active motor threshold(AMT),normalized motor-evoked potential(MEP),and cortical silent period(CSP)were evaluated by transcranial magnetic stimulation while participants performed a single-leg standing task.Results:Participants with CAI had significantly longer CSP at 100%of AMT and lower normalized MEP at 120%of AMT compared to lateral ankle sprain copers(CSP100%:p=0.003;MEP120%:p=0.044)and controls(CSP100%:p=0.041;MEP120%:p=0.006).Conclusion:This investigation demonstrate altered corticospinal excitability and inhibition of the tibialis anterior during single-leg standing in participants with CAI.Further research is needed to examine the effects of corticospinal maladaptations to motor control of the tibial anterior on postural control performance in those with CAI.  相似文献   

6.
Introduction: There is a large variety of body fat (BF) measurements, which differ in validity and reliability. The aim of this study was to measure subcutaneous adipose tissue (SAT) using ultrasound (US) in highly trained junior rowers in a field setting, establish fat patterning profiles, and compare the profiles between male and female athletes. Skinfold thickness (SKF) measurements were also taken and compared to US measurements. Methods: Sixteen athletes participated. US measurements were taken at eight sites and reported as a sum of SAT (D): DExcl (without embedded structures) and DIncl (including embedded structures). SKF was measured at three sites and reported as a sum of adipose tissue thickness (SUMSKF). Results: Mean SAT thickness (DIncl) was 27.6?±?12.4?mm for males and 65.5?±?11.8?mm for females. Females had significantly more embedded structures than males (P?=?.016). Significant correlations were found (P?<?.001, r?=?0.92) comparing SUMSKF to DIncl and between SKF and US measurements at the thigh site (P?<?.001, r?=?0.86). Conclusion: US is a suitable tool to measure BF in the field testing of athletes and enables measurements of SAT with an accuracy and reliability not reached before. The sum of thicknesses (DIncl or DExcl) can be used to represent subcutaneous fat based on accurate measurements of uncompressed SAT thicknesses.  相似文献   

7.
Mouth rinsing using a carbohydrate (CHO) solution has been suggested to improve physical performance in fasting participants. This study examined the effects of CHO mouth rinsing during Ramadan fasting on running time to exhaustion and on peak treadmill speed (Vpeak). In a counterbalanced crossover design, 18 sub-elite male runners (Age: 21?±?2 years, Weight: 68.1?±?5.7?kg, VO2max: 55.4?±?4.8?ml/kg/min) who observed Ramadan completed a familiarization trial and three experimental trials. The three trials included rinsing and expectorating a 25?mL bolus of either a 7.5% sucrose solution (CHO), a flavour and taste matched placebo solution (PLA) for 10?s, or no rinse (CON). The treatments were performed prior to an incremental treadmill test to exhaustion. Three-day dietary and exercise records were obtained on two occasions and analysed. Anthropometric characteristics were obtained and recorded for all participants. A main effect for mouth rinse on peak velocity (Vpeak) (CHO: 17.6?±?1.5?km/h; PLA: 17.1?±?1.4?km/h; CON: 16.7?±?1.2?km/h; P?ηp2?=?0.49) and time to exhaustion (CHO: 1282.0?±?121.3?s; PLA: 1258.1?±?113.4?s; CON: 1228.7?±?98.5?s; P?=?.002, ηp2?=?0.41) was detected, with CHO significantly higher than PLA (P?P?P?>?.05). Energy availability from dietary analysis, body weight, and fat-free mass did not change during the last two weeks of Ramadan (P?>?.05). This study concludes that carbohydrate mouth rinsing improves running time to exhaustion and peak treadmill speed under Ramadan fasting conditions.  相似文献   

8.
This study (1) compared the physiological responses and performance during a high-intensity interval training (HIIT) session incorporating externally regulated (ER) and self-selected (SS) recovery periods and (2) examined the psychophysiological cues underpinning SS recovery durations. Following an incremental maximal exercise test to determine maximal aerobic speed (MAS), 14 recreationally active males completed 2 HIIT sessions on a non-motorised treadmill. Participants performed 12?×?30?s running intervals at a target intensity of 105% MAS interspersed with 30?s (ER) or SS recovery periods. During SS, participants were instructed to provide themselves with sufficient recovery to complete all 12 efforts at the required intensity. A semi-structured interview was undertaken following the completion of SS. Mean recovery duration was longer during SS (51?±?15?s) compared to ER (30?±?0?s; p?d?=?1.46?±?0.46). Between-interval heart rate recovery was higher (SS: 19?±?9?b?min?1; ER: 8?±?5?b?min?1; p?d?=?1.43?±?0.43) and absolute time ≥90% maximal heart rate (HRmax) was lower (SS: 335?±?193?s; ER: 433?±?147?s; p?=?.075; d?=?0.52?±?0.39) during SS compared to ER. Relative time ≥105% MAS was greater during SS (90?±?6%) compared to ER (74?±?20%; p?d?=?0.87?±?0.40). Different sources of afferent information underpinned decision-making during SS. The extended durations of recovery during SS resulted in a reduced time ≥90% HRmax but enhanced time ≥105% MAS, compared with ER exercise. Differences in the afferent cue utilisation of participants likely explain the large levels of inter-individual variability observed.  相似文献   

9.
Purpose: The purpose of this study was to investigate whether loads carried in a backpack, with a load mass ranging from 0 to 20?kg, causes respiratory muscle fatigue. Methods: Eight males performed four randomised load carriage (LC) trials comprising 60?min walking at 6.5?km?h?1 wearing a backpack of either 0 (LC0), 10 (LC10), 15 (LC15) or 20?kg (LC20). Inspiratory (PImax) and expiratory (PEmax) mouth pressures were assessed prior to and immediately following each trial. Pulmonary gas exchange, heart rate (HR), blood lactate and glucose concentration and perceptual responses were recorded during the first and final 60?s of each trial. Results: Group mean PImax and PEmax were unchanged following 60-min load carriage in all conditions (p?>?.05). There was an increase over time in pulmonary gas exchange, HR and perceptions of effort relative to baseline measures during each trial (p?p?>?.05). Conclusions: These findings indicate that sub-maximal walking with no load or carrying 10, 15 or 20?kg in a backpack for up to 60?min does not cause respiratory muscle fatigue despite causing an increase in physiological, metabolic and perceptual parameters.  相似文献   

10.
Abstract

No published research has assessed sleep patterns of elite rugby union players following match-play. The present study examined sleep patterns of professional rugby union players, prior and post-match-play, to assess the influence of competition. Twenty-eight male rugby union players (24.4?±?2.9 years, 103.9?±?12.2?kg) competed in one of four competitive home matches. Player's sleep behaviours were monitored continuously using an Actiwatch® from two days before the match, until three days post-match. Repeated measures of analysis of variance (ANOVA) showed significant differences across the time points measured for time to bed (F?=?26.425, η2 ?=?0.495, p < .001), get up time (F?=?21.175, η2?=?0.440, p?<?.001), time spent in bed (F?=?10.669, η2?=?0.283, p?<?.001), time asleep (F?=?8.752, η2?=?0.245, p?<?.001) and percentage of time moving (F?=?4.602, η2?=?0.146 p?<?.05). Most notable, post hocs revealed a significant increase for time in bed the night before the match (p?<?.01; 95% CI?=?0?:?10–1?:?28?h; 9.7?±?13.5%) compared with the reference night sleep. Furthermore, time asleep significantly decreased post-match (p?<?.05; 95% CI?=??0:03 to ?1:59?h; ?19.5?±?19.8%) compared to two nights pre-match. Across all time points, sleep latency and efficiency for most players were considered abnormal compared to that expected in normal populations. The results demonstrate that sleep that is deprived post-match may have detrimental effects on the recovery process.  相似文献   

11.
Purpose: To determine the effect of limb selection (upper/lower), cuff width (small (6?cm)/medium (13?cm) upper; medium/large (18?cm) lower) and anthropometry on arterial occlusion pressure (AOP) in ischemic preconditioning (IPC). Methods: Twenty athletes (10 females and 10 males) had surface anthropometry and dual x-ray absorptiometry (DXA) assessments before using Doppler ultrasound to confirm AOP for each limb. Subsequently, 5?min of occlusion occurred, with near-infrared spectroscopy (NIRS) measuring muscle oxygenation changes. Resultant AOP was compared between sexes, limbs and cuff sizes using linear regression models. Results: Mean AOP was higher in the lower limbs than the upper limbs (161?±?18 vs. 133?±?12?mm?Hg; p?p?p?=?.222). Sex and resting systolic blood pressure (SBP) accounted for 77% (small cuff) to 83% (medium cuff) of variance in AOP for upper limbs, and 61% (medium cuff) to 63% (large cuff) in lower limbs. Including anthropometry accounted for 82% (small cuff) to 89% (medium cuff) and 78% (medium cuff) to 79% (large cuff) of variance for upper and lower limbs, respectively. Adding DXA variables improved the explained variance up to 83% (small cuff) to 91% (medium cuff) and 79% (medium cuff) to 87% (large cuff) for upper and lower limbs, respectively. NIRS data showed significantly greater tissue oxygenation changes in upper versus lower limbs. Conclusions: The AOP in athletes is dependent on limb occluded, sex, SBP, limb and cuff size, and body composition.  相似文献   

12.
The purpose of the present study was to compare acute changes in oxidative stress and inflammation in response to steady state and low volume, high intensity interval exercise (LV-HIIE). Untrained healthy males (n = 10, mean ± s: age 22 ± 3 years; VO2MAX 42.7 ± 5.0 ml · kg?1 · min?1) undertook three exercise bouts: a bout of LV-HIIE (10 × 1 min 90% VO2MAX intervals) and two energy-matched steady-state cycling bouts at a moderate (60% VO2MAX; 27 min, MOD) and high (80% VO2MAX; 20 min, HIGH) intensity on separate days. Markers of oxidative stress, inflammation and physiological stress were assessed before, at the end of exercise and 30 min post-exercise (post+30). At the end of all exercise bouts, significant changes in lipid hydroperoxides (LOOH) and protein carbonyls (PCs) (LOOH (nM): MOD +0.36; HIGH +3.09; LV-HIIE +5.51 and PC (nmol · mg?1 protein): MOD ?0.24; HIGH ?0.11; LV-HIIE ?0.37) were observed. Total antioxidant capacity (TAC) increased post+30, relative to the end of all exercise bouts (TAC (µM): MOD +189; HIGH +135; LV-HIIE +102). Interleukin (IL)-6 and IL-10 increased post+30 in HIGH and LV-HIIE only (P < 0.05). HIGH caused the greatest lymphocytosis, adrenaline and cardiovascular response (P < 0.05). At a reduced energy cost and physiological stress, LV-HIIE elicited similar cytokine and oxidative stress responses to HIGH.  相似文献   

13.
The protective action of remote ischaemic preconditioning (RIPC) has been demonstrated in the context of surgical interventions in cardiology. Application of RIPC to sports performance has been proposed, but its effect on the electrocardiogram (ECG) during exercise remains unknown. This exploratory study aims to measure the changes in ventricular repolarization observed during exercise following RIPC in healthy subjects. In an experimental randomized crossover study, 17 subjects underwent two bouts of constant load exercise tests at 75% and 115% of gas exchange threshold (GET). Prior to exercise, they were allocated to either control or RIPC intervention with four cycles of 5?min of ischaemia followed by 5?min of reperfusion. ECG was continuously recorded during the protocol. QT and RR intervals were measured every 30?s (on an average tracing of the preceding 10?s). Although the time course of RR intervals did not differ between the two interventions (p?=?.56 at 75% GET and p?=?.74 at 115% GET), a significant shortening of QT intervals (measured from Q onset to T end) was observed during exercise (mean?±?standard deviation of RIPC vs. control: ?32?±?19?ms at 75% GET (p?p?p?p?相似文献   

14.
Abstract

The aim of the present study was to investigate if resistance training (RT), performed with individualized recovery between sessions (RT-IND), promotes greater gains in strength and muscle mass and reduces the variability on adaptations compared to RT with fixed recovery intervals (RT-FIX). Twenty young men (age 21.9?±?3.3 years) were randomized in the RT-IND and RT-FIX groups. Five days before the beginning of the training, measurements of the root mean square of successive R-R intervals differences (RMSSD) values of each individual were performed to establish the baseline values. Before each RT session, the RMSSD values determined whether the participants from RT-IND protocol were recovered from the previous session. Participants performed the RT session only if RMSSD values had returned to the baseline, otherwise they had to wait for an additional 24?h. RT-FIX performed an RT session every 48?h. Muscle strength was measured by one-maximal repetition (1-RM) test and muscle cross-section area (CSA) of the vastus laterals by ultrasonography were assessed pre- and post-training. 1-RM values increased significantly from pre to post-training for both groups (RT-IND: 30% and RT-FIX: 42%, main time effect, P?<?0001), with no significant difference between groups. Muscle CSA increased significantly from pre to post-training (RT-IND: 15.7% and RT-FIX: 15.8%, main time effect, P?<?0001), with no significant difference between groups. In conclusion, RT-IND did not increase the gains in muscle strength and mass neither reduce the variability in muscle adaptations when compared to the RT-FIX.  相似文献   

15.
Purpose: This study investigated the physiological effects of wearing a mouthguard during submaximal treadmill exercise. Method: Twenty-four recreationally active males (Mage = 21.3 ± 2.4 years, Mheight = 1.78 ± 0.06 m, Mweight = 81.9 ± 10.6 kg, Mbody mass index = 25.8 ± 3.4 kg·m?2) performed incremental, continuous exercise at 2, 4, 6, and 8 mph (3.2, 6.4, 9.7, 12.9 kph) for 5 min at each speed on a motor-driven treadmill on 2 separate occasions in a randomized, crossover, counterbalanced design while wearing or not wearing a self-adaptable “boil and bite” mouthguard. Respiratory rate (RR), tidal volume (VT), ventilation (VE), oxygen consumption (VO2), respiratory exchange ratio (RER), and heart rate (HR) data were averaged during the last 60 s of each exercise stage; blood lactate (LA) was measured before exercise and 3 min and 10 min following exercise. Results: Repeated-measures analysis of variance revealed that mouthguard use failed to alter the response of RR, VT, VE, VO2, RER, and HR to treadmill exercise (p > .05), although each variable did increase in magnitude as a result of increasing treadmill speed (p < .001). Although increasing to above resting values at both 3 min and 10 min (p < .001) after cessation of exercise, LA levels also displayed no differences with mouthguard use (p > .05). Conclusion: Despite predictable increases in respiratory, metabolic, and cardiovascular variables in response to incremental exercise, the presence of a mouthguard failed to affect the magnitude or nature of these physiological responses.  相似文献   

16.
Objective: To examine the relationship between regular game-related caffeine consumption on sleep after an evening Super Rugby game. Methods: Twenty elite rugby union players wore a wrist-activity monitor to measure sleep for three days before, three days after and on the night of an evening Super Rugby game (19:00–21:00). Players ingested caffeine as they would normally (i.e. before and sometimes during a game) and saliva samples were collected before (17:00) and after (21:30) the game for caffeine concentration. Results: Compared to the nights leading up to the game, on the night of the game, players went to bed 3?h later (23:08?±?66?min vs 02:11?±?114?min; p?p?p?p?p?p?=?.06) on game night. Conclusion: Caffeine consumption before a Super Rugby game markedly increases post-game saliva caffeine levels. This may contribute to the observed 3.5?h delay in time at sleep onset and the 1.5?h reduction in sleep duration on the night of the game. This study highlights the need for a strategic approach to the use of caffeine within a Super Rugby team considering the potential effect on post-game sleep.  相似文献   

17.
The present study examined the effect of strength and endurance training order on the endocrine milieu associated with strength development and performance during concurrent training. A randomised, between-groups design was employed with 30 recreationally resistance-trained males completing one of four acute experimental training protocols; strength training (ST), strength followed by endurance training (ST-END), endurance followed by strength training (END-ST) or no training (CON). Blood samples were taken before each respective exercise protocol, immediately upon cessation of exercise, and 1?h post cessation of exercise. Blood samples were subsequently analysed for total testosterone, cortisol and lactate concentrations. Ability to maintain 80% 1RM during strength training was better in ST and ST-END than END-ST (both p?<?.05). Immediately following the respective exercise protocols all training interventions elicited significant increases in testosterone (p?<?.05). ST and END-ST resulted in greater increases in cortisol than ST-END (both p?<?.05). The testosterone:cortisol ratio was similar following the respective exercise protocols. Blood lactate concentrations post-training were greater following END-ST and ST than ST-END (both p?<?.05). Conducting endurance exercise prior to strength training resulted in impaired strength training performance. Blood cortisol and lactate concentrations were greater when endurance training was conducted prior to strength training than vice versa. As such, it may be suggested that conducting endurance prior to strength training may result in acute unfavourable responses to strength training when strength training is conducted with high loads.  相似文献   

18.
The insulin response following carbohydrate ingestion enhances creatine transport into muscle. Cinnamon extract is promoted to have insulin-like effects, therefore this study examined if creatine co-ingestion with carbohydrates or cinnamon extract improved anaerobic capacity, muscular strength, and muscular endurance. Active young males (n?=?25; 23.7?±?2.5?y) were stratified into 3 groups: (1) creatine only (CRE); (2) creatine+ 70?g carbohydrate (CHO); or (3) creatine+ 500?mg cinnamon extract (CIN), based on anaerobic capacity (peak power·kg?1) and muscular strength at baseline. Three weeks of supplementation consisted of a 5?d loading phase (20?g/d) and a 16?d maintenance phase (5?g/d). Pre- and post-supplementation measures included a 30-s Wingate and a 30-s maximal running test (on a self-propelled treadmill) for anaerobic capacity. Muscular strength was measured as the one-repetition maximum 1-RM for chest, back, quadriceps, hamstrings, and leg press. Additional sets of the number of repetitions performed at 60% 1-RM until fatigue measured muscular endurance. All three groups significantly improved Wingate relative peak power (CRE: 15.4% P?=?.004; CHO: 14.6% P?=?.004; CIN: 15.7%, P?=?.003), and muscular strength for chest (CRE: 6.6% P?P?P?P?P?P?P?=?.013; CHO: 10.0% P?=?.007; CIN: 17.3% P?P?=?.021) and CIN (15.5%, P?相似文献   

19.
Load carriage (LC) exercise in physically demanding occupations is typically characterised by periods of low-intensity steady-state exercise and short duration, high-intensity exercise while carrying an external mass in a backpack; this form of exercise is also known as LC exercise. This induces inspiratory muscle fatigue and reduces whole-body performance. Accordingly we investigated the effect of inspiratory muscle training (IMT, 50% maximal inspiratory muscle pressure (PImax) twice daily for six week) upon running time-trial performance with thoracic LC. Nineteen healthy males formed a pressure threshold IMT (n?=?10) or placebo control group (PLA; n?=?9) and performed 60?min LC exercise (6.5?km?h–1) followed by a 2.4?km running time trial (LCTT) either side of a double-blind six week intervention. Prior to the intervention, PImax was reduced relative to baseline, post-LC and post-LCTT in both groups (pooled data: 13?±?7% and 16?±?8%, respectively, p?PImax increased +31% (p?TT (+18%, p?PImax at each time point was unchanged (13?±?11% and 17?±?9%, respectively, p?>?.05). In IMT only, heart rate and perceptual responses were reduced post-LC (p?p?相似文献   

20.
Exercise has been demonstrated to have considerable effects upon haemostasis, with activation dependent upon the duration and intensity of the exercise bout. In addition, markers of coagulation and fibrinolysis have been shown to possess circadian rhythms, peaking within the morning (0600–1200?h). Therefore, the time of day in which exercise is performed may influence the activation of the coagulation and fibrinolytic systems. This study aimed to examine coagulation and fibrinolytic responses to short-duration high-intensity exercise when completed at different times of the day. Fifteen male cyclists (VO2max: 60.3?±?8.1?ml?kg?1?min?1) completed a 4-km cycling time trial (TT) on five separate occasions at 0830, 1130, 1430, 1730 and 2030. Venous blood samples were obtained pre- and immediately post-exercise, and analysed for tissue factor (TF), tissue factor pathway inhibitor (TFPI), thrombin–anti-thrombin complexes (TAT) and D-Dimer. Exercise significantly increased plasma concentrations of TF (p?p?p?p?p?=?.004) and TFPI (p?=?.031), with 0830 greater than 1730 (p .001), while 1730 was less than 2030?h (p?=?.008), respectively. There was no significant effect of time of day for TAT (p?=?.364) and D-Dimer (p?=?.228). Power output, TT time and heart rate were not significantly different between TTs (p?>?.05); however, percentage VO2max was greater at 1730 when compared to 2030 (p?=?.04). Due to a time-of-day effect present within TF, peaking at 0830, caution should be applied when prescribing short-duration high-intensity exercise bout within the morning in populations predisposed to hypercoagulability.  相似文献   

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