共查询到18条相似文献，搜索用时 218 毫秒
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β受体阻滞剂具有重要的临床价值,最近十年,纳米电化学传感器广泛用于此类药物的检测,成果丰硕。围绕传感器检测效能提升,学界近年来在修饰材料(纳米颗粒表面功能化及无机氧化物纳米材料、分子印迹膜、有机纳米材料的使用)、基体电极(丝网印刷电极的应用)、制备工艺(有序组装技术的研究)、检测方法(电致化学发光技术和化学计量学的引入)等方面做了大量新的尝试,取得一定进展,未来需强化同分离技术联用以及修饰电极微型化、阵列化等两个方面的研究。 相似文献
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近年来,生物传感器已广泛应用于基础研究、生物组分检测、临床疾病诊断、过程控制与检测、环境监控与保护等许多领域,电化学生物传感器是其中一个重要分支.纳米材料的尺寸小、比表面积大、表面原子配位不足、活性位点多等特性为生物传感器研究提供了新的途径,其迅猛发展对新型生物传感器的研制具有重要应用价值和意义.本文着重探讨了纳米材料在构建新型电化学生物传感器中的应用研究. 相似文献
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中枢神经抑制药具有药物与毒品的双重属性,相关检测研究一直都是热点。最近十年,电化学方法在该类药物的检验分析中发挥了重要作用,取得诸多成果。研究领域呈现“阿片类镇痛药研究较多,纳米材料修饰电极、膜电极、分子印迹技术应用较广;苯二氮类、巴比妥类镇静催眠药受关注程度偏低,普通电极、电致化学发光技术使用偏少”的显著特点。针对复杂生物样品,围绕灵敏检测,预计未来的研究重点包括拓展纳米碳纤维电极的应用、构建纳米电化学生物传感器、制备新型纳米分子印迹膜等三个方面。 相似文献
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《武汉工程职业技术学院学报》2021,(3)
β_2受体激动剂是一类具有多重属性与用途的药物,如何对其有效检测一直都是研究热点。简述了最近十年纳米复合物电化学传感器在该类药物检测中的应用进展,指出随着人们对用药安全、兴奋剂滥用和农兽药残留等方面日益关注,未来相关研究将聚焦于拓展分子印迹膜的应用、发展高效免疫传感器、构建电化学发光检测体系等三个方面。 相似文献
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局部麻醉药属于特殊临床用药,为降低其毒副作用,其品质必须严格管控,而电化学传感器由于具有操作简单、分析快速等优点,在该类药物剂量或纯度检测方面一直发挥着重要作用。本文对最近二十年来,局麻药电化学传感器的研究状况进行简要评述,重点分析该领域目前发展停滞的原因,指出其普遍存在创新性不足的问题。为了推动领域发展,未来应加强功能纳米材料的应用、新型镀覆方式的研究及科研思路的拓宽。 相似文献
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《实验室研究与探索》2019,(12)
基于高分子丝肽功能化石墨烯(SP-Gr)的制备、表征及在多巴胺电化学传感中的应用,构建了综合实验体系。采用透射电子显微镜、扫描电子显微镜、X-射线光电子能谱、X-射线衍射、紫外/可见光谱等表征丝肽功能化石墨烯纳米复合材料。将SP-Gr纳米复合物修饰至玻碳电极表面构建多巴胺电化学传感器,采用伏安法和交流阻抗谱表征传感界面,优化了实验条件,并实现了多巴胺电化学分析检测。 相似文献
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文章综述了纳米催化化学发光传感器的研究,主要包括乙醇传感器、胺传感器、硫化氢和醛类传感器以及糖类传感器,引用文献11篇。 相似文献
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XIAO Peng WANG Xin-qiang ZHANG Yun-huai 《重庆大学学报(英文版)》2006,5(3):161-164
1 Introduction a Among the numerous sensitive materials, carbon nanotubes (CNTs), both single and multiwalled, have been the focus of many studies recently [1,2]. In addition to high gas detection capability, it is established that CNT-based sensors opera… 相似文献
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The synthesis of polymer nanocomposites is an integral aspect of polymer nanotechnology. By inserting the nanometric inorganic
compounds, the properties of polymers improve and hence this has a lot of application depending upon the inorganic material
present in the polymers. Solvent casting is one of the easiest and less time consuming methods for the synthesis of polymer
nanocomposites. In this article we present different types of polymer composites, methods of synthesis, characterisation techniques
and different applications of polymer composites.
A Lagashetty is Head, Department of Engineering Chemistry, Appa Institute of Engineering and Technology, Gulbarga, Karnataka.
His research interests are synthesis, characterization and applications of nanomaterials and polymer nanocomposites.
A Venkataraman is Head, Department of Materials Science, Gulbarga University, Gulbarga. His research interests are nanomaterials,
nanomaterials as sensors, polymer synthesis and polymer nanocomposites. 相似文献
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An in situ calibration system is a versatile exploration instrument for electrochemical sensors investigating the biochemical properties of the marine environment. The purpose of this paper is to describe the design of an auto-calibrating system for electrochemical （pH） sensors, which permits two-point in situ calibration, suitable for long-term measurement in deep sea aqueous environments. Holding multiple sensors, the instrument is designed to perform long-term measurements and in situ calibrations at abyssal depth （up to 4000 m）. The instrument is composed of a compact fluid control system which is pressure-equilibrated and designed for deep-sea operation. In situ calibration capability plays a key role in the quality and reproducibility of the data. This paper focuses on methods for extending the lifetime of the instrument, considering the fluidics design, mechanical design, and low-power consumption of the electronics controller. The instrument can last 46 d under normal operating conditions, fulfilling the need for long-term operation. Data concerning pH measured during the KNOX18RR cruise （Mid-Atlantic Ridge, July-August, 2008） illustrate the desirable properties of the instrument. Combined with different electrodes （pH, H2, H2S, etc.）, it should be of great utility for the study of deep ocean environments, including water column and diffuse-flow hydrothermal fluids. 相似文献
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王骞 《鞍山师范学院学报》2011,13(6):17-20
综述了TiO2光催化纳米材料的光催化降解原理及在环境保护中的应用现状.介绍了光催化纳米材料的特点及发展历程.对光催化纳米材料在处理水污染、治理大气污染、控制噪声污染等方面的应用进行了综合性的评述.同时指出光催化纳米材料存在光利用率低、催化效率低、对工作条件的高要求等问题,并提出了光催化纳米材料与传统环境污染治理方式相结合的发展前景. 相似文献
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Because brushless direct current (BLDC) motors have the advantages of a compact size, high power density, high efficiency, and long operating life time, they are widely used in many industrial products and electric traction systems. It is known that the BLDC motors have no brushes for commutation. They are commutated with electronically commutation. So, the rotor position information of the BLDC motors must be known to understand which winding will be energized according to the energizing sequence. In most of the existing BLDC motor drivers, rotor position information is detected by Hall effect sensors. This kind of mechanical position sensors will bring additional connections and costs, reliability decrease and noise increase. In order to improve the control performance and extend the range of speed regulation for BLDC motors, a position sensorless control method is proposed in this paper. In the proposed control method, rotor position information of the BLDC motors is detected from the back electromagnetic forces (back-EMFs) which are estimated by an unknown-input observer with line to line currents and line to line voltages. For the purpose of verifying the effectiveness of the proposed control method, a model is built and simulated on the Matlab/Simulink platform. The simulation results show that the speed regulation performance of BLDC motors is improved compared with using Hall effect sensors. At the same time, the reliability of the BLDC motors is improved and the costs of them are reduced because the position sensor is eliminated. 相似文献
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疼痛是各种疾病最常见的症状,是当今困扰人类健康最严重的问题之一。目前临床上应用的镇痛药种类有限,且大多具有镇痛效果不强和／或成瘾、耐受等明确的副作用,致使大量的疼痛患者得不到有效的治疗。因而急需开发新型不成瘾和副作用小的镇痛药。由于难以在人体对疼痛进行深入的机制和药效研究,往往通过建立疼痛的动物模型来筛选和鉴定镇痛候选药物。很多研究表明,根据动物疼痛模型的镇痛效果,很难预测其在人类身上的镇痛作用,导致临床研究常常出现令人困惑和模糊混乱的评价结果。新兴的人类疼痛实验模型,有望成为镇痛新药研发中联系动物实验和临床试验的有机桥梁,用于评价候选镇痛新药的作用机制和疗效,可为临床试验提供更加科学的设计方案,增加临床试验的成功率。该文拟对在健康志愿者身上进行的人类疼痛实验模型的研究进展进行综述,以期为加快新型镇痛药物的研发进程提供借鉴和参考。 相似文献