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1.
We evaluate the performance of the most common estimators of latent Markov (LM) models with covariates in the presence of direct effects of the covariates on the indicators of the LM model. In LM modeling it is common practice not to model such direct effects, ignoring the consequences that might have on the overall model fit and the parameters of interest. However, in the general literature about latent variable modeling it is well known that unmodeled direct effects can severely bias the parameter estimates of the model at hand. We evaluate how the presence of direct effects in?uences the bias and efficiency of the 3 most common estimators of LM models, the 1-step, 2-step, and 3-step approaches. Furthermore, we propose amendments (that were thus far not used in the context of LM modeling) to the 2- and 3-step approaches that make it possible to account for direct effects and eliminate bias as a consequence. This is done by modeling the (possible) direct effects in the first step of the stepwise estimation procedures. We evaluate the proposed estimators through an extensive simulation study, and illustrate them via a real data application. Our results show, first, that the augmented 2-step and 3-step approaches are unbiased and efficient estimators of LM models with direct effects. Second, ignoring the direct effects leads to biased estimates with all existing estimators, the 1-step approach being the most sensitive.  相似文献   

2.
Latent Markov models with covariates can be estimated via 1-step maximum likelihood. However, this 1-step approach has various disadvantages, such as that the inclusion of covariates in the model might alter the formation of the latent states and that parameter estimation could become infeasible with large numbers of time points, responses, and covariates. This is why researchers typically prefer performing the analysis in a stepwise manner; that is, they first construct the measurement model, then obtain the latent state classifications, and subsequently study the relationship between covariates and latent state memberships. However, such a stepwise approach yields downward-biased estimates of the covariate effects on initial state and transition probabilities. This article, shows how to overcome this problem using a generalization of the bias-corrected 3-step estimation method proposed for latent class analysis (Asparouhov & Muthén, 2014; Bolck, Croon, & Hagenaars, 2004; Vermunt, 2010). We give a formal derivation of the generalization to latent Markov models and discuss how it can be used with many time points by incorporating it into a Baum–Welch type of expectation-maximization algorithm. We evaluate the method through a simulation study and illustrate it using an application on household financial portfolio change. Our study shows that the proposed correction method yields unbiased parameter estimates and accurate standard errors, except for situations with very poorly separated classes and a small sample.  相似文献   

3.
The 3-step approach has been recently advocated over the simultaneous 1-step approach to model a distal outcome predicted by a latent categorical variable. We generalize the 3-step approach to situations where the distal outcome is predicted by multiple and possibly associated latent categorical variables. Although the simultaneous 1-step approach has been criticized, simulation studies have found that the performance of the two approaches is similar in most situations (Bakk & Vermunt, 2016). This is consistent with our findings for a 2-LV extension when all model assumptions are satisfied. Results also indicate that under various degrees of violation of the normality and conditional independence assumption for the distal outcome and indicators, both approaches are subject to bias but the 3-step approach is less sensitive. The differences in estimates using the two approaches are illustrated in an analysis of the effects of various childhood socioeconomic circumstances on body mass index at age 50.  相似文献   

4.
In this article, 3-step methods to include predictors and distal outcomes in commonly used mixture models are evaluated. Two Monte Carlo simulation studies were conducted to compare the pseudo class (PC), Vermunt’s (2010), and the Lanza, Tan, and Bray (LTB) 3-step approaches with respect to bias of parameter estimates in latent class analysis (LCA) and latent profile analysis (LPA) models with auxiliary variables. For coefficients of predictors of class membership, results indicated that Vermunt’s method yielded more accurate estimates for LCA and LPA compared to the PC method. With distal outcomes of latent classes and latent profiles, the LTB method produced the lowest relative bias of coefficient estimates and Type I error rates close to nominal levels.  相似文献   

5.
For some time, there have been differing recommendations about how and when to include covariates in the mixture model building process. Some have advocated the inclusion of covariates after enumeration, whereas others recommend including them early on in the modeling process. These conflicting recommendations have led to inconsistent practices and unease in trusting modeling results. In an attempt to resolve this discord, we conducted a Monte Carlo simulation to examine the impact of covariate exclusion and misspecification of covariate effects on the enumeration process. We considered population and analysis models with both direct and indirect paths from the covariates to the latent class indicators. As expected, misspecified covariate effects most commonly led to the overextraction of classes. Findings suggest that the number of classes could be reliably determined using the unconditional latent class model, thus our recommendation is that class enumeration be done prior to the inclusion of covariates.  相似文献   

6.
Factor mixture modeling (FMM) has been increasingly used to investigate unobserved population heterogeneity. This study examined the issue of covariate effects with FMM in the context of measurement invariance testing. Specifically, the impact of excluding and misspecifying covariate effects on measurement invariance testing and class enumeration was investigated via Monte Carlo simulations. Data were generated based on FMM models with (1) a zero covariate effect, (2) a covariate effect on the latent class variable, and (3) covariate effects on both the latent class variable and the factor. For each population model, different analysis models that excluded or misspecified covariate effects were fitted. Results highlighted the importance of including proper covariates in measurement invariance testing and evidenced the utility of a model comparison approach in searching for the correct specification of covariate effects and the level of measurement invariance. This approach was demonstrated using an empirical data set. Implications for methodological and applied research are discussed.  相似文献   

7.
Abstract

Factor mixture models are designed for the analysis of multivariate data obtained from a population consisting of distinct latent classes. A common factor model is assumed to hold within each of the latent classes. Factor mixture modeling involves obtaining estimates of the model parameters, and may also be used to assign subjects to their most likely latent class. This simulation study investigates aspects of model performance such as parameter coverage and correct class membership assignment and focuses on covariate effects, model size, and class-specific versus class-invariant parameters. When fitting true models, parameter coverage is good for most parameters even for the smallest class separation investigated in this study (0.5 SD between 2 classes). The same holds for convergence rates. Correct class assignment is unsatisfactory for the small class separation without covariates, but improves dramatically with increasing separation, covariate effects, or both. Model performance is not influenced by the differences in model size investigated here. Class-specific parameters may improve some aspects of model performance but negatively affect other aspects.  相似文献   

8.
In applied research, such as with motivation theories, typically many variables are theoretically implied predictors of an outcome and several interactions are assumed (e.g., Watt, 2004). However, estimation problems that might arise when several interaction and/or quadratic effects are analyzed simultaneously have not been investigated because simulation studies on interaction effects in the structural equation modeling framework have mainly focused on small models that contain single interaction effects. In this article, we show that traditional approaches can provide estimates with low accuracy when complex models are estimated. We introduce an adaptive Bayesian lasso approach with spike-and-slab priors that overcomes this problem. Using a complex model in a simulation study, we show that the parameter estimates of the proposed approach are more accurate in situations with high multicollinearity or low reliability compared with a standard Bayesian lasso approach and typical frequentist approaches (i.e., unconstrained product indicator approach and latent moderated structures approach).  相似文献   

9.
Latent class methods can be used to identify unobserved subgroups which differ in their observed data. Researchers are often interested in outcomes for the identified subgroups and in some disciplines time-to-event outcome measures are common, e.g., overall survival in oncology. In this study Monte Carlo simulation is used to evaluate the empirical properties of latent class effect estimates on a time-to-event distal outcome using one, two and three-step approaches. Both standard and inclusive bias-corrected three-step approaches are considered. One-step latent class effect estimates are shown to be superior to the evaluated alternatives. Both the two-step approach and a standard three-step approach, where subjects are partially assigned to latent classes, produced unbiased estimates with nominal confidence interval coverage when latent classes were well separated, but not otherwise.

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10.
Although it is currently best practice to directly model latent factors whenever feasible, there remain many situations in which this approach is not tractable. Recent advances in covariate-informed factor score estimation can be used to provide manifest scores that are used in second-stage analysis, but these are currently understudied. Here we extend our prior work on factor score recovery to examine the use of factor score estimates as predictors both in the presence and absence of the same covariates that were used in score estimation. Results show that whereas the relation between the factor score estimates and the criterion are typically well recovered, substantial bias and increased variability is evident in the covariate effects themselves. Importantly, using covariate-informed factor score estimates substantially, and often wholly, mitigates these biases. We conclude with implications for future research and recommendations for the use of factor score estimates in practice.  相似文献   

11.
Regression mixture models, which have only recently begun to be used in applied research, are a new approach for finding differential effects. This approach comes at the cost of the assumption that error terms are normally distributed within classes. This study uses Monte Carlo simulations to explore the effects of relatively minor violations of this assumption. The use of an ordered polytomous outcome is then examined as an alternative that makes somewhat weaker assumptions, and finally both approaches are demonstrated with an applied example looking at differences in the effects of family management on the highly skewed outcome of drug use. Results show that violating the assumption of normal errors results in systematic bias in both latent class enumeration and parameter estimates. Additional classes that reflect violations of distributional assumptions are found. Under some conditions it is possible to come to conclusions that are consistent with the effects in the population, but when errors are skewed in both classes the results typically no longer reflect even the pattern of effects in the population. The polytomous regression model performs better under all scenarios examined and comes to reasonable results with the highly skewed outcome in the applied example. We recommend that careful evaluation of model sensitivity to distributional assumptions be the norm when conducting regression mixture models.  相似文献   

12.
We consider a general type of model for analyzing ordinal variables with covariate effects and 2 approaches for analyzing data for such models, the item response theory (IRT) approach and the PRELIS-LISREL (PLA) approach. We compare these 2 approaches on the basis of 2 examples, 1 involving only covariate effects directly on the ordinal variables and 1 involving covariate effects on the latent variables in addition.  相似文献   

13.
Mixture models capture heterogeneity in data by decomposing the population into latent subgroups, each of which is governed by its own subgroup-specific set of parameters. Despite the flexibility and widespread use of these models, most applications have focused solely on making inferences for whole or subpopulations, rather than individual cases. This article presents a general framework for computing marginal and conditional predicted values for individuals using mixture model results. These predicted values can be used to characterize covariate effects, examine the fit of the model for specific individuals, or forecast future observations from previous ones. Two empirical examples are provided to demonstrate the usefulness of individual predicted values in applications of mixture models. The first example examines the relative timing of initiation of substance use using a multiple event process survival mixture model, whereas the second example evaluates changes in depressive symptoms over adolescence using a growth mixture model.  相似文献   

14.
This series of simulation studies evaluate, in the context of applied research settings, the impact of the parameterization of the covariance structure of the growth mixture model (GMM) on the regression coefficient and standard error estimates in the 3-step method. The results show that the 1-step approach performs better than the 3-step method across the simulation studies. However, the performance of the 3-step method depends slightly or importantly on the parameterization of the GGM from the first step, on the inclusion or not of the predictor at the first step of the analysis, on the population model, and on the type (i.e., logit vs. linear) and size of the regression coefficient estimates.  相似文献   

15.
When conducting longitudinal research, the investigation of between-individual differences in patterns of within-individual change can provide important insights. In this article, we use simulation methods to investigate the performance of a model-based exploratory data mining technique—structural equation model trees (SEM trees; Brandmaier, Oertzen, McArdle, & Lindenberger, 2013)—as a tool for detecting population heterogeneity. We use a latent-change score model as a data generation model and manipulate the precision of the information provided by a covariate about the true latent profile as well as other factors, including sample size, under the possible influences of model misspecifications. Simulation results show that, compared with latent growth curve mixture models, SEM trees might be very sensitive to model misspecification in estimating the number of classes. This can be attributed to the lower statistical power in identifying classes, resulting from smaller differences of parameters prescribed by the template model between classes.  相似文献   

16.
Abstract

Bayesian alternatives to frequentist propensity score approaches have recently been proposed. However, few studies have investigated their covariate balancing properties. This article compares a recently developed two-step Bayesian propensity score approach to the frequentist approach with respect to covariate balance. The effects of different priors on covariate balance are evaluated and the differences between frequentist and Bayesian covariate balance are discussed. Results of the case study reveal that both the Bayesian and frequentist propensity score approaches achieve good covariate balance. The frequentist propensity score approach performs slightly better on covariate balance for stratification and weighting methods, whereas the two-step Bayesian approach offers slightly better covariate balance in the optimal full matching method. Results of a comprehensive simulation study reveal that accuracy and precision of prior information on propensity score model parameters do not greatly influence balance performance. Results of the simulation study also show that overall, the optimal full matching method provides the best covariate balance and treatment effect estimates compared to the stratification and weighting methods. A unique feature of covariate balance within Bayesian propensity score analysis is that we can obtain a distribution of balance indices in addition to the point estimates so that the variation in balance indices can be naturally captured to assist in covariate balance checking.  相似文献   

17.
Latent class models are often used to assign values to categorical variables that cannot be measured directly. This “imputed” latent variable is then used in further analyses with auxiliary variables. The relationship between the imputed latent variable and auxiliary variables can only be correctly estimated if these auxiliary variables are included in the latent class model. Otherwise, point estimates will be biased. We develop a method that correctly estimates the relationship between an imputed latent variable and external auxiliary variables, by updating the latent variable imputations to be conditional on the external auxiliary variables using a combination of multiple imputation of latent classes and the so-called three-step approach. In contrast with existing “one-step” and “three-step” approaches, our method allows the resulting imputations to be analyzed using the familiar methods favored by substantive researchers.  相似文献   

18.
Regression mixture models are a new approach for finding differential effects which have only recently begun to be used in applied research. This approach comes at the cost of the assumption that error terms are normally distributed within classes. The current study uses Monte Carlo simulations to explore the effects of relatively minor violations of this assumption, the use of an ordered polytomous outcome is then examined as an alternative which makes somewhat weaker assumptions, and finally both approaches are demonstrated with an applied example looking at differences in the effects of family management on the highly skewed outcome of drug use. Results show that violating the assumption of normal errors results in systematic bias in both latent class enumeration and parameter estimates. Additional classes which reflect violations of distributional assumptions are found. Under some conditions it is possible to come to conclusions that are consistent with the effects in the population, but when errors are skewed in both classes the results typically no longer reflect even the pattern of effects in the population. The polytomous regression model performs better under all scenarios examined and comes to reasonable results with the highly skewed outcome in the applied example. We recommend that careful evaluation of model sensitivity to distributional assumptions be the norm when conducting regression mixture models.  相似文献   

19.
Structural equation models with interaction and quadratic effects have become a standard tool for testing nonlinear hypotheses in the social sciences. Most of the current approaches assume normally distributed latent predictor variables. In this article, we describe a nonlinear structural equation mixture approach that integrates the strength of parametric approaches (specification of the nonlinear functional relationship) and the flexibility of semiparametric structural equation mixture approaches for approximating the nonnormality of latent predictor variables. In a comparative simulation study, the advantages of the proposed mixture procedure over contemporary approaches [Latent Moderated Structural Equations approach (LMS) and the extended unconstrained approach] are shown for varying degrees of skewness of the latent predictor variables. Whereas the conventional approaches show either biased parameter estimates or standard errors of the nonlinear effects, the proposed mixture approach provides unbiased estimates and standard errors. We present an empirical example from educational research. Guidelines for applications of the approaches and limitations are discussed.  相似文献   

20.
This simulation study examines the efficacy of multilevel factor mixture modeling (ML FMM) for measurement invariance testing across unobserved groups when the groups are at the between level of multilevel data. To this end, latent classes are generated with class-specific item parameters (i.e., factor loading and intercept) across the between-level classes. The efficacy of ML FMM is evaluated in terms of class enumeration, class assignment, and the detection of noninvariance. Various classification criteria such as Akaike’s information criterion, Bayesian information criterion, and bootstrap likelihood ratio tests are examined for the correct enumeration of between-level latent classes. For the detection of measurement noninvariance, free and constrained baseline approaches are compared with respect to true positive and false positive rates. This study evidences the adequacy of ML FMM. However, its performance heavily depends on the simulation factors such as the classification criteria, sample size, and the magnitude of noninvariance. Practical guidelines for applied researchers are provided.  相似文献   

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