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1.
研究目的:探讨碎裂QRS波对急性心肌梗死患者的短期预后评估的价值,及其对ST段抬高和非ST段抬高型心肌梗死(STEMI和NSTEMI)患者不同的预测价值。创新要点:证实了碎裂QRS波对急性心肌梗死尤其是ST段抬高型心肌梗死的短期预后价值,对早期再灌注治疗有指导意义。研究方法:通过对碎裂QRS波发生及持续时间的详细记录(见图1、2),评价出现碎裂QRS波的STEMI及NSTEMI患者住院期间发生恶性心律失常、泵功能衰竭及住院死亡的风险(见图3;表3–5),并观察早期经皮冠状动脉介入治疗(PCI)对预后的不同影响(见表6)。重要结论:1.急性心肌梗死(尤其是STEMI)患者心电图出现碎裂QRS波短期内易发生恶性心律失常、左心室功能不全及死亡;2.对出现碎裂QRS波的急性心肌梗死患者,早期PCI再灌注治疗可改善患者短期预后。  相似文献   

2.
急性冠状动脉综合征高致死性因素及护理对策   总被引：1，自引：0，他引：1  
急性冠状动脉综合征(acute coronary syndrome,ACS)是指由于冠状动脉粥样硬化斑块破裂、血小板粘附聚集、凝血因子激活和血栓形成,引起冠状动脉不完全阻塞所致.临床可表现为不稳定性心绞痛(unstable angina,UA)、非ST段抬高心肌梗死(not ST segment elevation myocardial infarction,NSTEMI)以及ST段抬高性心肌梗死(ST segment elevation myocardial infarction,STEMI)和心源性猝死(SCD).因其病死率高,是国内外公认的急性心血管疾病[1].  相似文献   

3.
目的:探讨急性下壁梗死时体表心电图指标对判断心肌梗死相关动脉的意义.方法:对62例急性下壁心肌梗死的三种体表心电图指标和冠状动脉造影结果进行对比分析.结果:(1)相关梗死动脉右冠状动脉(RCA)组45例,左回旋支(LCX)组17例.(2)右冠状动脉组中ST段抬高幅度Ⅲ°＞Ⅱ°发生率明显多于左回旋支组,具有显著性差异(P＜0.05).ST段抬高幅度Ⅲ°＞Ⅱ°诊断右冠状动脉闭塞的敏感性为86.7%,特异性为76.4%.(3)右冠状动脉组中aVL导联ST段压低发生率明显多于左回旋支组,具有显著性差异(P＜0.05).aVL导联ST段压低诊断右冠状动脉闭塞的敏感性为71.1%,特异性为82.4%.(4)左回旋支组中合并V7～V9导联ST段抬高发生率明显多于右冠状动脉组,差别具有显著性差异(P＜0.05).合并V7～V9导联ST段抬高诊断左回旋支闭塞的敏感性为70.6%,特异性为88.9%.结论:ST段抬高幅度Ⅲ°＞Ⅱ°、aVL导联ST段压低以及合并V7～V9导联ST段抬高对判断急性下壁心肌梗死相关血管有重要的预测价值.  相似文献   

4.
目的：探讨急性下壁心肌梗死临床体表心电图与冠脉病变血管的相关性。方法：对照分析83例急性下壁心肌梗死患者入院时的心电图Ⅱ、Ⅲ导联ST段抬高的比值及Ⅴ1、V3导联ST段抬高和Ⅰ导联ST段偏移与冠状动脉梗死相关病变血管的关系。结果：83例患者中，61例为右冠状动脉（RCA）闭塞所致者ST段抬高Ⅲ〉Ⅱ、Ⅲ相等Ⅱ，分别为59、4例。Ⅴ3导联抬高58例，压低3例。Ⅰ导联ST段下移57例，等电位线4例（P〈0．05）。左旋支（LCX）闭塞所致22例ST段抬高Ⅲ、Ⅱ相等与Ⅲ〈Ⅱ分别为20、2例，Ⅴ3导联ST段抬高大于Ⅲ导联19例，等电位线3例（P〈0．05）。结论：急性下壁心肌梗死相关冠脉病变血管以RCA为主，少部分为LCX病变。ST段抬高Ⅲ〉Ⅱ合并伴有STⅤ3〉Ⅲ和Ⅰ导联ST段压低对诊断右冠状动脉阻塞具有较高的诊断价值。Ⅲ／Ⅱ相等合并STⅤ3〉Ⅲ判定急左旋支性阻塞具有较高的诊断价值，其差别有统计学意义。  相似文献   

5.
《学周刊C版》2017,(16):125-126
目的:探索胸痛中心快速启动介入导管室对急性ST段抬高型心肌梗死患者救治效果的影响。方法:选择在本院介入导管室实施PCI治疗符合急性ST段抬高型心肌梗死诊断标准的患者200例为研究对象,按患者住院时间顺序进行分组,选取2012年1月-2013年12月的患者100例作为对照组,按照传统常规模式启动介入导管室实施PCI治疗;选取2014年1月-2015年12月的患者100例作为观察组,按胸痛中心建设要求快速启动介入导管室。比较两组患者进门至入导管室的平均时间、首次医疗接触到球囊扩张时间和平均住院时间。结果:观察组启动介入导管室所需的平均时间(12.09±3.75)min短于对照组(33.83±6.62)min(t=28.57,P<0.01);观察组门—球时间及门—球时间达标率分别为(65.62±8.26)min、97.0%均优于对照组(96.23±9.58)min、62.0%(t=29.61,P<0.01);观察组患者的平均住院时间为(14.11±5.39)d短于对照组(20.37±8.14)d(t=6.26,P<0.01)。结论:规范化胸痛中心快速启动介入导管室,明显缩短了STEMI患者PCI的门—球时间,缩短了患者的住院时间。  相似文献   

6.
目的:探讨通过序列地测定急性心肌梗死(AMI)患者经皮冠脉介入(PCI)前后血浆 BNP浓度,探讨了直接和延迟PCI对AMI患者心功能转归的影响.方法:顺序选入2005-12-2006-11月就诊于河北医科大学第三医院心内科的ST段抬高型心肌梗死(STEMI)患者45名.采用酶联免疫吸附法(ELISA)分别检测入院即时、术后7d和30d时的血浆脑利钠肽(BNP)浓度.结果:直接PCI组和延迟PCI组血浆BNP浓度在术前无显著性差异,PCI术后7d、30d的血浆BNP浓度与治疗前比较均有显著下降(P<0.05),术后30d下降更为显著(P<0.01);两组间比较PCI术后7d(183.4±56.2pg/mL vs 243.7±85.2pg/mL P<0.05)和30d(108.3±36.7pg/mL vs 139.4±76.8pg/mL P<0.05)均有显著性差异,前者均低于后者.结论:AMI患者接受PCI治疗后,血浆BNP浓度逐渐下降,直接PCI较延迟PCI治疗血浆BNP浓度下降显著,直接PCI治疗对住院期间AMI患者心功能的改善优于延迟PCI治疗.  相似文献   

7.
目的 观察ST段抬高心肌梗死(STEMI)患者急性期中性粒细胞和血小板计数的动态变化,并探讨其与心肌梗死面积及心肌灌注水平的关系.方法 连续选取于发病12 h内行直接经皮冠状动脉介入治疗(PCI)的STEMI患者43例,于直接PCI术前后多个时间点检测中性粒细胞和血小板计数,并分别分析与心肌酶峰值及校正TIMI帧数(CTFC)的关系.结果 中性粒细胞计数丁卣接PCI术后24 h达到最高值(8.22±3.00)×109/L,术后7 d降至最低值(4.30±1.44)×109/L;血小板计数丁术后72 h降到最低值(195.3±61.0)×109/L,术后7 d恢复至基线水平.中性粒细胞计数的基线值与CK峰值(r=0.406,P=0.008)和CK-MB峰值(r=0.388,P=0.011)正相关,术后24 h最高值与CK峰值(r=0.623,P<0.001)及CK-MB峰值(r=0.528,P<0.001)的相关性更为密切.血小板计数的基线值(r=0.347,P=0.024)和最低值(r=0.355,P=0.027)分别与CTFC旱负相关.在调整了相关的冠心病危险因素后,术后24 h中性粒细胞计数对CK及CK-MB峰值的独立预测价值更高(B=0.678,P<0.001;β=0.441,P=0.004),PCI术后72 h血小板计数(B=-0.330,P=0.032)对CTFC有独市预测价值.结论 行直接PCI治疗的STEMI患者急件期尤其术后24 h中性粒细胞水平升高与较大的心肌梗死范围相关;而血小板计数的最低值越低,术后心肌血流灌注程度越差.  相似文献   

8.
目的:观察心安灵对冠脉结扎麻醉犬的保护作用.方法:麻醉犬冠脉结扎复制心肌缺血模型.观察给药后ST段偏移总和(Σ-ST)、ST段抬高≥2mv的个数(N-ST)、LDH、CK释放的变化.结果:心安灵可显著减少冠脉结扎所致的Σ-ST抬高和N-ST增加,同时减少血清中LDH和CK的释放.结论:心安灵对麻醉犬冠状动脉结扎所致的心肌缺血具有明显改善作用.  相似文献   

9.
目的通过对急性下壁心肌梗死时心电图Ⅱ、Ⅲ导联ST段抬高幅度（STⅡ／Ⅲ比值）的比较分析，来预测梗死相关动脉（infarction related artery IRA）。方法回顾性分析72例首次急性下壁心肌梗死患者的入院心电图与冠状动脉造影资料。结果对急性下壁心肌梗死时心电图指标STⅡ／Ⅲ与IRA关系的统计分析表明，STⅡ／Ⅲ在右冠状动脉（RCA）组绝大多数小于1而左旋支（LCX）组多大于等于1（P〈0．011，排除RCA和LCX皆有显著病变的病例后仍然P〈0．01。结论心电图STⅡ／Ⅲ比值是预测急性下壁心肌梗死患者IRA的较准确的指标。  相似文献   

10.
急性ST段抬高型心肌梗死继发心脏破裂的预测因素分析   总被引：2，自引：0，他引：2  
研究目的：心脏破裂是急性ST段抬高型心肌梗死最严重的并发症之一,病情凶险,死亡率高。通过明确心肌梗死后出现心脏破裂并发症的危险因素,早期识别心脏破裂高危人群,有利于在急性心肌梗死的早期采取干预措施以减少心脏破裂的发生。创新要点：既往缺乏对中国sT段抬高型心肌梗死继发心脏破裂的系统风险评估,本研究采用回顾性队列研究的方法,完善并健全中国多中心的急性心肌梗死数据库,样本总量达到9798例,为国内同类研究中样本量最多。既往的国外文献报道：女性、高龄、心梗后就诊时间延迟、前壁心肌梗死、溶栓治疗等是心肌梗死后心脏破裂的独立危险因素。本研究在中国人群验证以上危险因素的基础上首次提出就诊时血色素下降及白细胞计数的升高与随后发生的心脏破裂密切相关。新的心脏破裂预测因素的发现有利于对心脏破裂更精细化的危险分层,早期识别心脏破裂高危人群。研究方法：建立中国多中心心肌梗死数据库,比较发生心脏破裂与未发生心脏破裂患者临床特点的差异,筛选敏感特异的心脏破裂的独立预测因素。重要结论：中国人群急性ST段抬高型心肌梗死后心脏破裂的发生率是1．82％,独立预测因素主要包括：高龄、女性、就诊时静息心率增快、前壁心肌梗死、心功能不全、就诊时间延迟、肾功能不全、贫血与白细胞计数升高。本文第一次提出就诊时贫血状态及白细胞计数的升高时与心脏破裂的发生直接相关。  相似文献   

11.
Objective: To determine the association between tea consumption and the risk of stroke. Methods: We searched the PubMed database from January 1966 to March 2012 and reviewed reference lists of retrieved articles to identify relevant studies. Studies were included if they reported relative risks (RRs) and corresponding 95% confidence intervals (CIs) of stroke with respect to three or more categories of tea consumption. A random-effects model was used to combine the study-specific risk estimates. Results: Fourteen studies, consisting of 513 804 participants with a median follow-up of 11.5 years, were included in this meta-analysis. We observed a modest but statistically significant inverse association between tea consumption and risk of stroke. An increase of three cups/d in tea consumption was associated with a 13% decreased risk of stroke (RR 0.87; 95% CI, 0.81–0.94). The decreased risk of stroke with tea consumption was consistent among most subgroups. Based on the three studies that provided results for stroke subtypes, tea consumption was also inversely associated with the risk of ischemic stroke (RR 0.76; 95% CI, 0.69–0.84), but not cerebral hemorrhage (RR 0.96; 95% CI, 0.82–1.11) or subarachnoid hemorrhage (RR 0.81; 95% CI, 0.57–1.16). Conclusions: Tea consumption is associated with a decreased risk of stroke, particularly ischemic stroke. More well-designed, rigorously conducted studies are needed in order to make confident conclusions about the association between tea consumption and stroke subtypes.  相似文献   

12.
A meta-analysis was performed to address the efficacy and safety of paclitaxel-eluting stent (PES) in ST-segment elevation myocardial infarction (STEMI) patients. A systematic literature search was conducted to identify all randomized clinical trials in mortality, recurrent myocardial infarction (rMI), repeat revascularization (RR), and stent thrombosis (ST). A total of 4190 STEMI patients were enrolled in six randomized trials comparing PES with bare-metal stent (BMS). The pooled repeat revascularization rate was 5.7% in PES group, significantly lower than 10.0% in BMS group with an odds ratio (OR) of 0.56, 95% confidence interval (CI) [0.44, 0.72] (P<0.00001). No significant difference was found between PES and BMS groups in mortality at one year after the indexing procedure (3.9% vs. 5.1%, OR 0.88, 95% CI [0.63, 1.21], P=0.42). Similarly, rMI rate did not differ significantly between the two groups (3.4% vs. 4.1%, OR 0.80, 95% CI [0.56, 1.13], P=0.21). PES was also associated with the comparable pooled rate of definite stent thrombosis with BMS (2.3% vs. 2.4%, OR 0.81, 95% CI [0.52, 1.26], P=0.35). The results show that PES improved clinical outcomes in STEMI patients with a decreased need for repeat revascularization and no concerns for safety.  相似文献   

13.
Objective: There is no simple or feasible post-procedural intravascular ultrasound (IVUS) score to predict major adverse cardiac events (MACE) in patients undergoing drug-eluting stents (DES) implantation. The aim of this study is to validate a new IVUS score for predicting MACE. Methods: A total of 295 patients (with 322 lesions) were enrolled. IVUS score was calculated in each lesion based on five IVUS morphological characteristics: inflow/outflow disease, malapposition, underexpansion, tissue protrusion, and edge dissection (iMUTE score). We assigned two points to an underexpansion and one point for each presence of other factors. Patients were divided into low score (iMUTE score<2, n=137) and high score (iMUTE score≥2, n=158) groups. Results: At one year follow-up, a trend was seen in favor of the low iMUTE score group in MACE (3.65% vs. 10.10%; P=0.052), and there was more target vessel revascularization (TVR) in the high iMUTE score group compared with low score group (6.96% vs. 1.46%; P=0.044). Low iMUTE score was an independent predictor of freedom from TVR at one year (adjusted hazard ratio (HR) 0.5, 95% confidence interval (CI) 0.1–0.8; P=0.02). Conclusions: Post-procedural IVUS iMUTE scoring was simple and feasible in clinical practice, and can provide independent prognostic value for TVR in patients undergoing DES implantation.  相似文献   

14.

Objective

The relative preventative efficacy of amiodarone and lidocaine for ventricular fibrillation (VF) after release of an aortic cross-clamp (ACC) during open heart surgery has not been determined. This meta-analysis was designed to systematically evaluate the influence of amiodarone, lidocaine, or placebo on the incidence of VF after ACC.

Methods

Prospective randomized controlled trials (RCTs) that compared the VF-preventative effects of amiodarone with lidocaine, or amiodarone or lidocaine with placebo were included. PubMed, EMBASE, and the Cochrane Library were searched for relevant RCTs. Fixed or randomized effect models were applied according to the heterogeneity of the data from the selected studies.

Results

We included eight RCTs in the analysis. Pooled results suggested that the preventative effects of amiodarone and lidocaine were comparable (relative risk (RR)=1.12, 95% confidence interval (CI): 0.70 to 1.80, P=0.63), but both were superior to the placebo (amiodarone, RR=0.71, 95% CI: 0.51 to 1.00, P=0.05; lidocaine, RR=0.63, 95% CI: 0.46 to 0.88, P=0.006). The percentage of patients requiring electric defibrillation counter shocks (DCSs) did not differ significantly among patients administered amiodarone (RR=0.21, 95% CI: 0.04 to 1.19, P=0.08), lidocaine (RR=2.44, 95% CI: 0.13 to 44.02, P=0.55), or the placebo (RR=0.56, 95% CI: 0.25 to 1.25, P=0.16).

Conclusions

Amiodarone and lidocaine are comparably effective in preventing VF after ACC, but the percentage of patients who subsequently require DCSs does not differ among those administered amiodarone, lidocaine, or placebo.
  相似文献   

15.
Objective: XRCC1 polymorphism is a research hotpot in individual treatment for non-small cell lung cancer (NSCLC). To obtain the association between XRCC1 polymorphism and clinical outcome of platinum-based treatment for NSCLC, a meta-analysis was conducted. Methods: Databases including PubMed, Embase, Cochrane, and Chinese National Knowledge Infrastructure (CNKI) were searched for publications that met the inclusion criteria. A fixed effect model was used to estimate pooled odds ratio (OR) and hazard ratio (HR) with 95% confidence interval (CI) for the association between XRCC1 Arg399Gln and response or survival of platinum-based treatment for advanced NSCLC. A chi-squared-based Q-test was used to test the heterogeneity hypothesis. Egger’s test was used to check publication bias. Results: Seventeen published case-control studies that focus on the association between XRCC1 Arg399Gln and response or survival of platinum-based treatment for advanced NSCLC in 2 256 subjects were included in this meta-analysis, of whom 522 were AA genotypes (23.2% frequency), 916 AG genotypes (40.6% frequency), and 818 GG genotypes (36.2% frequency). The overall response rate (ORR) was 45.2% (110/243) for AA genotype patients, 29.9% for AG genotype (73/244), and 30.7% for GG genotype (124/403). The heterogeneity test did not show any heterogeneity and the Egger’s test did not reveal an obvious publication bias among the included studies. The meta-analysis indicated that AA genotype patients presented higher response rates toward platinum drug treatment compared with G model (GG+GA) patients (GG vs. AA model: OR=0.489, 95% CI 0.266–0.900, P=0.021; AG vs. AA model: OR=0.608, 95% CI 0.392–0.941, P=0.026; GA+AA vs. GG model: OR=1.259, 95% CI 0.931–1.701, P=0.135; GG+GA vs. AA model: OR=0.455, 95% CI 0.313–0.663, P=0.0001). However, no evidence validates XRCC1 associates with the survival following platinum drug therapy. Conclusions: Our meta-analysis suggested that XRCC1 Arg399Gln is related with the sensitivity of NSCLC patients to platinum-based treatment. AA genotype patients present more desirable curative effectiveness compared with other patients.  相似文献   

16.
Objective:Although drug-eluting stent(DES) implantation is the primary treatment modality for bare-metal stent(BMS) in-stent restenosis(ISR),little is known about the efficacy and safety profile of DES in the treatment of DES-ISR.The goal of this study was to compare the clinical outcomes following DES treatment for BMS-ISR and DES-ISR.Methods:Rates of major adverse cardiac events(MACE) were compared in 97 consecutive patients who underwent DES implantation for the treatment of ISR(56 BMS-ISR and 41 DES-ISR) from January 2004 to December 2008.Results:Baseline clinical and procedural characteristics were comparable,except that the DES used in the BMS-ISR group was longer and had a larger diameter.The length of follow-up was(28.60±1.96) and(20.34±1.54) months for the BMS-ISR and DES-ISR groups,respectively.One patient(1.8%) experienced non-cardiac mortality and one(1.8%) had target-vessel revascularization(TVR) in the BMS-ISR group.In the DES-ISR group,three patients(7.3%) died of sudden death with a documented acute ST-segment elevation myocardial infarction,and three suffered TVR(7.3%).Kaplan-Meier analysis indicated that cumulative survival probability and MACE-free probability were both significantly lower for the DES-ISR group(log rank test P=0.047 and P=0.005,respectively).In Cox regression analysis,DES-ISR remained an independent predictor for future MACE occurrence after adjustment for other factors(compared with BMS-ISR,risk ratio(RR)=8.743,95% confidence interval(CI) 1.54-49.54,P=0.014).Switching to a different type of DES to treat DES-ISR did not improve the prognosis.Conclusion:DES-ISR patients had a poorer prognosis than BMS-ISR patients after DES therapy.  相似文献   

17.
OBJECTIVES: To determine the association between children's exposure to maternal intimate partner violence (IPV) and behavior problems as measured by the parent report version of the Child Behavior Checklist (CBCL). METHODS: The study population was comprised of 167 2- to 17-year-old children of Seattle women with police-reported or court-reported intimate partner abuse. The CBCL normative population served as the comparison group. Risk of behavior problems was calculated among the exposed children, in the presence and absence of a history of reported child maltreatment, relative to the normative population. Multiple logistic regression served as the primary method of analysis. RESULTS: Children exposed to maternal IPV were more likely to have borderline to clinical level scores on externalizing (i.e., aggressive, delinquent) behavior (RR=1.6, 95% CI: 1.2, 2.1) and total behavioral problems (RR=1.4, 95% CI: 1.1, 1.9) compared to the CBCL normative sample after adjusting for age and sex. Children who were exposed to maternal IPV and were victims of child maltreatment were more likely to receive borderline to clinical level scores on internalizing (i.e., anxious, depressed) behaviors (RR=2.6, 95% CI: 1.5, 3.6), externalizing (i.e., aggressive, delinquent) behaviors (RR=3.0, 95% CI: 1.9, 4.0) and total behavioral problems (RR=2.1, 95% CI: 1.2, 3.2) compared to the CBCL normative sample after adjusting for age and sex. CONCLUSIONS: Exposure to maternal IPV is significantly associated with child behavioral problems both in the presence and absence of co-occurring child maltreatment. Appropriate attention to the mental health of children living in households with IPV is needed.  相似文献   

18.
Slight elevations in cardiac troponin I and T are frequently observed after percutaneous coronary intervention (PCI). Contrast-induced acute kidney injury (CI-AKI) is a complex syndrome induced by exposure to intravascular contrast media (CM). Currently, the relationships between the CM, pre-existing kidney insufficiency, CI-AKI, and myonecrosis after elective PCI are unclear. To investigate the relationship between CI-AKI and post-procedural myonecrosis (PMN) after PCI, we analyzed 327 non-ST-segment elevation acute coronary syndrome subjects undertaking elective PCI. The levels of cardiac troponins (cTns), cTnI and cTnT, at baseline and on at least one occasion 18–24 h after PCI were measured. We also recorded serum levels of creatinine (SCr) and the urine albumin:creatinine ratio (ACR) before coronary angiography, and 24–48 h and 48–72 h after contrast administration. A post-procedure increase in cTns was detected in 16.21% (53/327) of subjects with cTns levels >99th to 599th percentile upper reference limit (URL). Twenty-seven patients (8.26%) developed CI-AKI. CI-AKI occurred more often in subjects with PMN than in those without PMN (20.8% versus 5.8%, respectively, P=0.001). Multiple logistic regression analysis revealed that pre-existing microalbuminuria (MA) was an important independent predictor of PMN (OR: 3.31; 95% CI: 1.26–8.65, P=0.01). However, there was no correlation between the incidence of CI-AKI and PMN (OR: 2.38; 95% CI: 0.88–6.46, P=0.09). We conclude that pre-existing MA was not only an important independent predictor of CI-AKI but also of PMN.  相似文献   

19.
Objective:This study aims to determine the mechanisms underlying restenosis and ischemia-reperfusion injury of the myocardium after percutaneous coronary intervention (PCI).Methods:The present study examined serial changes (5 min,30 min,2 h,6 h,and 24 h after PCI) in circulating P-selectin,plasminogen activator inhibitor-1 (PAI-1),magnesium (Mg),and creatine kinase-myocardial band fraction (CK-MB) levels,which may be associated with restenosis and myocardial injury in patients undergoing PCI.The occurrence rates of major adverse cardiovascular events were collected over a six-month follow-up.Results:PCI induced an early elevation of P-selectin,which correlated positively with the inflation pressure used in the PCI procedure.PCI also caused a significant and sustained decrease in serum Mg in PCI patients,without an effect on PAI-1.An increase in CK-MB was observed in PCI patients,although values were within normal reference range.In addition,elevated P-selectin and decreased Mg measured shortly after the coronary angioplasty procedure were associated with recurrent treatment and heart failure,respectively.Conclusions:Our study demonstrates that PCI induces temporal changes of P-selectin,Mg,and CK-MB,which may be involved in restenosis and ischemia-reperfusion injury.These findings highlight the need for using antiplatelet therapy and Mg to reduce the risks associated with PCI.  相似文献   

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