FLOSSWorld全球调查结果显示服务器更多使用开源软件     

Rishab A.Ghosh  刘佐达 《中国教育网络》2007,(1):39-39

FLOSSWorld调查的主体由5部分构成,包括:个人(Private sector)、政府(Government sector)、开源社区参与者(Open Source participants community)、高校管理者(Heigher Education Institutes——Administrators)、高校信息部门主管(Heigher Education Institute——ITManagers)  相似文献   

Synthetic and biological studies on a cyclopolypeptide of plant origin     

Dahiya R  Kumar A 《Journal of Zhejiang University. Science. B》2008,9(5):391-400

Objective: A natural cyclic peptide previously isolated from Citrus medica was synthesized by coupling oftetrapep-tide units Boc-Leu-Pro-Trp-Leu-Ome and Boc-Ile-Ala-Ala-Gly-Ome after proper deprotection at carboxyl and amino terminals followed by cyclization of linear octapeptide segment.Methods: Solution phase technique was adopted for the synthesis of cyclooctapeptide--sarcodactylamide.Required tetrapeptide units were prepared by coupling of Boc-protected dipeptides viz.Boc-Leu-Pro-OH and Boc-Ile-Ala-OH with respective dipeptide methyl esters Trp-Leu-Ome and Ala-Gly-Ome.Cyclization of linear octapeptide unit was done by p-nitrophenyl ester method.The structure of synthesized cyclopolypeptide was elucidated by FTIR,1H NMR,13C NMR,FABMS spectral data and elemental analysis.The newly synthesized peptide was evaluated for dif-ferent pharmacological activities including antimicrobial,anthelmintic and cytotoxic activities.Results: Synthesis of sarcodac-tylamide was accomplished with >78% yield utilizing dicyclohexylcarbodiimide (DCC) as coupling agent.Newly synthesized peptide possessed potent cytotoxic activity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines,in addition to moderate anthelmintic activity against earthworms Megascoplex konkanensis,Pontoscotex corethruses and Eudrilus sp.Moreover,cyclopolypeptide displayed good antimicrobial activity against pathogenic fungi Candida albicans and Gram-negative bacteria Pseudomonas aeruginosa,in comparison to standard drugs griseofulvin and ciprofloxacin.Conclusion: Solution phase technique employing DCC and triethylamine (TEA) as base proved to be effective for the synthesis of natural cyclooctapeptide.N-methyl morpholine (NMM) was found to be a better base for the cyclization of linear octapeptide unit in comparison to TEA and pyridine.  相似文献   

Developmental links of very early phonological and language skills to second grade reading outcomes: strong to accuracy but only minor to fluency     

Puolakanaho A  Ahonen T  Aro M  Eklund K  Leppänen PH  Poikkeus AM  Tolvanen A  Torppa M  Lyytinen H 《Journal of learning disabilities》2008,41(4):353-370

The authors examined second grade reading accuracy and fluency and their associations via letter knowledge to phonological and language predictors assessed at 3.5, 4.5, and 5.5 years in children in the Jyv?skyl? Longitudinal Study of Dyslexia. Structural equation modeling showed that a developmentally highly stable factor (early phonological and language processing [EPLP]) behind key dyslexia predictors (i.e., phonological awareness, short-term memory, rapid naming, vocabulary, and pseudoword repetition) could already be identified at 3.5 years. EPLP was significantly associated with reading and spelling accuracy and by age with letter knowledge. However, EPLP had only a minor link with reading fluency, which was additionally explained by early letter knowledge. The results show that reading accuracy is well predicted by early phonological and language skills. Variation in fluent reading skills is not well explained by early skills, suggesting factors other than phonological core skills. Future research is suggested to explore the factors behind the development of fast and accurate decoding skills.  相似文献   

关于猫、黄金、老头和金字塔的三个不同故事     

崔志强  E.T  重重 《教学随笔》2002,(1)

两位考古专家一同前去参观金字塔,晚上便住在开罗市郊的一家小旅馆里,一个人留在房间里面写工作日记,另一个人就上街闲逛。他在路边发现有一个老妇人在卖一只黑色的工艺猫,要价1000元。他忽然发现这只猫的两只眼睛竟是两颗大  相似文献   

基于国家教育标准的地理教材   总被引：1，自引：0，他引：1  

A.David Hill  石昍 《中学语文教学参考(高中生版(学语文))》1995,(5)

为进一步增强美国地理教育。我们要做的许多事情之一就是改进教材的质量。其中最主要的三个方面的任务是:(1)开发优良的教材,(2)利用教师联盟的在职培训网络和职前教育计划培训教师使用这种新教材,(3)通过提供强有力的课程指导,特别是将教材与师资培训和基于国家  相似文献   

心路历程--流逝的岁月     

Dr.Robert S.Herman 《海外英语》2003,(6):4-5

Old age gives us the privilege to explore, to innovate, to challenge.Dear Friends,This is our twelfth monthly column and the first-year anniversary of our conversation together in the pages of Overseas English. We call this a milestone in English. Is there a Chinese word for it?I would like to begin our column with one of my own poems.  相似文献   

世界范围的师范教育问题——环球十六国师范教育考察     

霍华德B.莱维特  刘振汉 《新疆教育学院学报》1992

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为大学毕业生开设的速成本科护理课程与传统护理课程学生成绩的比较     

McDonaldW.K!英  周红波 《复旦教育论坛》1996,(2)

由于技术进步,经济波动,护理短缺,护理患者所需知识的增加,人们对新的护理教育模式更感兴趣。目前美国各地许多护理院校已采取了各种不同模式的学士后护理教育,大致有三种新的模式:对非护理学院毕业生的护理学士学位课程,普通硕土学位课程和护理博士学位课程。作者对新旧两种护理学士学位课程的学生进行了比较,发现新模式培养的学生在护理成绩和注册护士考试通过率方面明显高于传统模式教育的学生。  相似文献   

克鲁普斯卡娅论儿童阅读的教育作用     

Л.В.托多罗夫  杨进 《教育理论与实践》1983,(4)

在新的社会主义社会条件下,苏联教育学解决了许多尖锐的、有碍于培养和教育劳动人民和正在成长中的一代人的社会矛盾。文化革命消除了广大劳动人民目不识丁的状况,初等义务教育和七年制义务教育的彻底实现,使广大人民群众都能享受包括文学作品在内的世界文化成就。作为一位教育家——马克思主义者,克鲁普斯卡娅认为,科学以及建立在世界历史经验基础上的理论知识,是人类的最高成就。她提出,要全面地、经常  相似文献   

加拿大住家保姆计划     

Prof.Dr.James  C.Jordan 《出国与就业》2001,(8)

作为加拿大住家保姆的资格 专门的加拿大住家保姆计划的目的是:当没有足够的加拿大人去从事这个工作时,引入外国人到加拿大做住家保姆工作。 当申请成功者接到加拿大雇佣授权,允许他们到加拿大作住家保姆的工作,到加拿大后,三年内必须完成两年这样的雇佣,才能向加拿大  相似文献