Exploring Podcast Adoption Intention via Perceived Social Norms,Interpersonal Communication,and Theory of Planned Behavior     

Yi Mou  Carolyn A. Lin 《广播与电子媒介杂志》2015,59(3):475-493

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The Impact of Reorganization of Staff Using the Core Competencies as a Framework for Staff Training and Development     

Rachel A. Erb 《期刊图书馆员》2015,68(1-4):92-105

In 2012, the Colorado State University Libraries’ Technical Services Department reorganized, which provided the catalyst to reconfigure paraprofessional staff positions. Staff are either part of the state classified system or are considered administrative professionals; both categories dictate the extent to which positions can be expanded to encompass assisting with managing electronic resources. This presentation is an account of how NASIG’s Core Competencies for Electronic Resource Librarians are scalable to be used in restructuring staff positions that assist with managing resources. Special attention will be paid to various modes of training that enable paraprofessionals to learn processes associated with electronic resources work.  相似文献   

Yer Doin’ it Wrong: How NOT to Interact with Vendors,Publishers, or Librarians     

Katy Ginanni  Anne E. McKee  Jenni Wilson  Linda A. Brown 《期刊图书馆员》2015,68(1-4):255-261

Three librarians who have extensive experience working in libraries or for publishers, vendors, or consortia presented an informal discussion on librarian–vendor relationships. The audience was encouraged to participate. Problems were articulated; speakers and audience members contributed suggestions for better approaches or behaviors when handling difficult situations.  相似文献   

A novel alternating current multiple array electrothermal micropump for lab-on-a-chip applications     

A. Salari  M. Navi  C. Dalton 《Biomicrofluidics》2015,9(1)

The AC electrothermal technique is very promising for biofluid micropumping, due to its ability to pump high conductivity fluids. However, compared to electroosmotic micropumps, a lack of high fluid flow is a disadvantage. In this paper, a novel AC multiple array electrothermal (MAET) micropump, utilizing multiple microelectrode arrays placed on the side-walls of the fluidic channel of the micropump, is introduced. Asymmetric coplanar microelectrodes are placed on all sides of the microfluidic channel, and are actuated in different phases: one, two opposing, two adjacent, three, or all sides at the same time. Micropumps with different combinations of side electrodes and cross sections are numerically investigated in this paper. The effect of the governing parameters with respect to thermal, fluidic, and electrical properties are studied and discussed. To verify the simulations, the AC MAET concept was then fabricated and experimentally tested. The resulted fluid flow achieved by the experiments showed good agreement with the corresponding simulations. The number of side electrode arrays and the actuation patterns were also found to greatly influence the micropump performance. This study shows that the new multiple array electrothermal micropump design can be used in a wide range of applications such as drug delivery and lab-on-a-chip, where high flow rate and high precision micropumping devices for high conductivity fluids are needed.  相似文献   

Disrupting the wall accumulation of human sperm cells by artificial corrugation     

H. A. Guidobaldi  Y. Jeyaram  C. A. Condat  M. Oviedo  I. Berdakin  V. V. Moshchalkov  L. C. Giojalas  A. V. Silhanek  V. I. Marconi 《Biomicrofluidics》2015,9(2)

Many self-propelled microorganisms are attracted to surfaces. This makes their dynamics in restricted geometries very different from that observed in the bulk. Swimming along walls is beneficial for directing and sorting cells, but may be detrimental if homogeneous populations are desired, such as in counting microchambers. In this work, we characterize the motion of human sperm cells ∼60 μm long, strongly confined to ∼25 μm shallow chambers. We investigate the nature of the cell trajectories between the confining surfaces and their accumulation near the borders. Observed cell trajectories are composed of a succession of quasi-circular and quasi-linear segments. This suggests that the cells follow a path of intermittent trappings near the top and bottom surfaces separated by stretches of quasi-free motion in between the two surfaces, as confirmed by depth resolved confocal microscopy studies. We show that the introduction of artificial petal-shaped corrugation in the lateral boundaries removes the tendency of cells to accumulate near the borders, an effect which we hypothesize may be valuable for microfluidic applications in biomedicine.  相似文献   

Microfluidic sampling system for tissue analytics     

A. Hokkanen  I. Stuns  P. Schmid  A. Kokkonen  F. Gao  A. Steinecker  J. Budczies  P. Heimala  L. Hakalahti 《Biomicrofluidics》2015,9(5)

We have developed a microfluidics based sampling system for tissue analytics. The proof-of-concept of the sampling system was demonstrated by extracting lipid samples from tissue biopsies. The sample collection system consists of a disposable silicon based multiport microneedle integrated with polymer microfluidics. The polymethyl methacrylate polymer microfluidic chip has a 10 μl sample reservoir and actuation membranes for liquid pumping. A special automated robotic system was developed to control the positioning of the needle and the sampling procedure on preselected spots on the tissue. Real breast cancer tissue samples were used to test the feasibility of the sampling system. We successfully measured indicative cancer biomarkers from the tissue surface. Phosphatidylcholine and phosphoethanolamine were extracted from the tissue membrane with methyl tert-butyl ether solvent and detected by mass spectrometry. In the future, this tool could be used in characterization of preoperative biopsies and tumour tissues removed during surgery.  相似文献   

Isolation and enrichment of low abundant particles with insulator-based dielectrophoresis     

Alexandra LaLonde  Maria F. Romero-Creel  Mario A. Saucedo-Espinosa  Blanca H. Lapizco-Encinas 《Biomicrofluidics》2015,9(6)

Isolation and enrichment of low-abundant particles are essential steps in many bio-analytical and clinical applications. In this work, the capability of an insulator-based dielectrophoresis (iDEP) device for the detection and stable capture of low abundant polystyrene particles and yeast cells was evaluated. Binary and tertiary mixtures of particles and cells were tested, where the low-abundant particles had concentration ratios on the order of 1:10 000 000 compared to the other particles present in the mixture. The results demonstrated successful and stable capture and enrichment of rare particles and cells (trapping efficiencies over 99%), where particles remained trapped in a stable manner for up to 4 min. A device with four reservoirs was employed for the separation and enrichment of rare particles, where the particles of interest were first selectively concentrated and then effectively directed to a side port for future collection and analysis. The present study demonstrates that simple iDEP devices have appropriate screening capacity and can be used for handling samples containing rare particles; achieving both enrichment and isolation of low-abundant particles and cells.  相似文献   

Osmotically driven drug delivery through remote-controlled magnetic nanocomposite membranes     

A. Zaher  S. Li  K. T. Wolf  F. N. Pirmoradi  O. Yassine  L. Lin  N. M. Khashab  J. Kosel 《Biomicrofluidics》2015,9(5)

Implantable drug delivery systems can provide long-term reliability, controllability, and biocompatibility, and have been used in many applications, including cancer pain and non-malignant pain treatment. However, many of the available systems are limited to zero-order, inconsistent, or single burst event drug release. To address these limitations, we demonstrate prototypes of a remotely operated drug delivery device that offers controllability of drug release profiles, using osmotic pumping as a pressure source and magnetically triggered membranes as switchable on-demand valves. The membranes are made of either ethyl cellulose, or the proposed stronger cellulose acetate polymer, mixed with thermosensitive poly(N-isopropylacrylamide) hydrogel and superparamagnetic iron oxide particles. The prototype devices'' drug diffusion rates are on the order of 0.5–2 μg/h for higher release rate designs, and 12–40 ng/h for lower release rates, with maximum release ratios of 4.2 and 3.2, respectively. The devices exhibit increased drug delivery rates with higher osmotic pumping rates or with magnetically increased membrane porosity. Furthermore, by vapor deposition of a cyanoacrylate layer, a drastic reduction of the drug delivery rate from micrograms down to tens of nanograms per hour is achieved. By utilizing magnetic membranes as the valve-control mechanism, triggered remotely by means of induction heating, the demonstrated drug delivery devices benefit from having the power source external to the system, eliminating the need for a battery. These designs multiply the potential approaches towards increasing the on-demand controllability and customizability of drug delivery profiles in the expanding field of implantable drug delivery systems, with the future possibility of remotely controlling the pressure source.  相似文献   

How much exercise are older adults living in nursing homes doing in daily life? A cross-sectional study     

Philipe De Souto Barreto  Laurent Demougeot  Bruno Vellas  Yves Rolland 《Journal of sports sciences》2015,33(2):116-124

Information on the amount of exercise practised by nursing home (NH) residents is scarce. This study aimed at describing NH residents’ participation in exercise classes, as well as to examine whether the presence of a professional exercise instructor in the facilities is associated with residents’ exercise habits. The cross-sectional data of 5402 residents (median age = 88 years; mostly women (75.2%)) from 163 NHs in France were analysed. Adjusted logistic and linear regressions were performed to examine whether the presence of a professional exercise instructor in the NH was associated with exercise habits: exercise participation, frequency, duration, and levels. From the 5402 participants, 1914 were participating in exercise classes provided in the NH. Most of them had an exercise frequency of 1x/week or less. Median duration of exercise sessions was 45 min. Exercise levels were rated as: highly active (n = 487), intermediately active (n = 1096), and poorly active (n = 331). The presence of a professional exercise instructor working in the facility was significantly associated with exercise participation and with higher exercise frequencies and levels, and session duration. In conclusion, the presence of professional exercise instructors is associated with better exercise habits in NH residents. Improved exercise habits may potentially be translated into better health in this population.  相似文献   

The impact of data reduction on the intra-trial reliability of a typical measure of lower limb musculoskeletal stiffness     

Mark P. Moresi  Elizabeth J. Bradshaw  David A. Greene  Geraldine A. Naughton 《Journal of sports sciences》2015,33(2):180-191

Double-leg repeated jumping tasks are commonly used as measures of lower limb stiffness in exercise science research. Within similar stiffness calculations, variation in data-reduction criteria exists. The impact of these varied data-reduction methods on stiffness measures is unknown. Sixteen adolescent female participants from varied physical activity backgrounds performed 15 self-paced, bent-knee continuous jumps (CJb) on two force plates. Leg stiffness was calculated as the ratio of the peak force and the centre of mass displacement for each contact. Using combinations of criteria based on previous literature, 83 data-reduction methods were applied to the raw data. Data reduction suitability was assessed based on intra-trial reliability, the number of participants excluded and the average contacts excluded. Four data-reduction methods were deemed suitable for use with adolescent female populations, with three consecutive contacts within 1 SD of the average jump frequency considered optimal. The average individual stiffness values were not greatly influenced by the data-reduction method; however, for a single participant, a stiffness change of up to 6 kN · m^?1 (30%) was observed. The role and potential impact of data-reduction methods used to evaluate measures of lower limb stiffness during repeated jumping tasks warrants consideration.  相似文献