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Human serum paraoxonase-1 (PON1), an enzyme on HDL prevents oxidation of LDL thereby preventing the development of atherosclerosis. Studies done so far have lead to conflicting results. As studies are lacking in North-West Indian Punjabi’s, a distinct ethnic group with high incidence of coronary artery disease, we determined PONase activity in this population. It has been postulated that sudden lowering of serum PONase may lead to precipitation of acute myocardial infarction. We determined serum PONase activity and lipids in 100 patients each of AMI (within 24 h of onset), stable CAD and 100 age and sex matched healthy controls. These were again determined after 6 weeks in AMI patients. The mean serum PONase activity was lowest in AMI patients (23.26 U/ml) followed by stable CAD patients (102.0 U/ml) where as in controls was highest (179.8 U/ml). In patients with AMI, activity was significantly higher at 6 weeks as compared to that after acute event (49.39 %; p < 0.05). Sudden lowering of serum PONase activity in a population which already has lower activity may be one of the risk factors for development of AMI.  相似文献   
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The School of Physics at the University of Sydney has introduced voluntary workshop tutorials in large first‐year courses. The tutorials are based on informal cooperative groupings with structured worksheets and short hands‐on activities. In this study we explore the relationship between attendance at the workshop tutorials and student performance in examinations. We show that about 80% of the students attend more than two‐thirds of the voluntary tutorials. Discounting the students who attend very few tutorials, on average, examination marks improve significantly with increased tutorial attendance. In particular, on average, students with poor senior high school scores have significantly better examination marks if they work in the same group for eight or more tutorials than those who do not work in the same groups. There is evidence that the improvement in examination performance is more pronounced in qualitative concept questions, most dramatically again for students who did poorly in senior high school.  相似文献   
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This article explores the implications of the knowledge society for education and education systems. It focuses on how education systems in Asia are contributing to the development and sustainability of the knowledge society through creating powerful professional learning communities. The article explores how professional collaboration, at scale, is being used to generate social capital in order to promote educational transformation and improvement. The article draws upon a range of theoretical perspectives to examine how professional learning communities are contributing to educational improvement and the construction of new knowledge. The article concludes by arguing that disciplined, collective and inter-dependent learning is critical for the knowledge society to be sustained.  相似文献   
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The paper heralds a new pedagogical model known as the Science Teachers Accelerated Programme as a platform to upgrade the qualifications of secondary school science teachers throughout the Pacific region. Based on a tripartite partnership between a higher education provider, a regional government and a cohort of science teachers, the model offers an accelerated Bachelor’s degree programme to the cohort. Using this tripartite partnership model, a pilot of the Science Teachers Accelerated Programme is underway between the University of the South Pacific, the Government of Samoa and a cohort of science teachers in Samoa. The underpinning activities garnering social and academic integration are highlighted with analytics. The strengths, challenges and opportunities of the new, cohort-taught science model are presented with relevant diagnoses, interventions and adaptive works carried out in the first half of the delivery plan. While the Government of Samoa is considering the implementation of a second cycle, the University of the South Pacific is considering extending the model to other regional countries.  相似文献   
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