Bandpass sorting of heterogeneous cells using a single surface acoustic wave transducer pair     

Gergely Simon  Caroline Busch  Marco A. B. Andrade  Julien Reboud  Jonathan M. Cooper  Marc P. Y. Desmulliez  Mathis O. Riehle  Anne L. Bernassau 《Biomicrofluidics》2021,15(1)

Separation and sorting of biological entities (viruses, bacteria, and cells) is a critical step in any microfluidic lab-on-a-chip device. Acoustofluidics platforms have demonstrated their ability to use physical characteristics of cells to perform label-free separation. Bandpass-type sorting methods of medium-sized entities from a mixture have been presented using acoustic techniques; however, they require multiple transducers, lack support for various target populations, can be sensitive to flow variations, or have not been verified for continuous flow sorting of biological cells. To our knowledge, this paper presents the first acoustic bandpass method that overcomes all these limitations and presents an inherently reconfigurable technique with a single transducer pair for stable continuous flow sorting of blood cells. The sorting method is first demonstrated for polystyrene particles of sizes 6, 10, and 14.5 μm in diameter with measured purity and efficiency coefficients above 75 ± 6% and 85 ± 9%, respectively. The sorting strategy was further validated in the separation of red blood cells from white blood cells and 1 μm polystyrene particles with 78 ± 8% efficiency and 74 ± 6% purity, respectively, at a flow rate of at least 1 μl/min, enabling to process finger prick blood samples within minutes.  相似文献   

The role that schools hold in supporting young people with selective mutism: a systematic literature review     

Joe White  Caroline Bond 《Journal of Research in Special Educational Needs》2022,22(3):232-242

Schools are expected to hold an increasingly central role in co-ordinating support for children with mental health needs. However, the role that schools hold in supporting pupils with selective mutism (SM) is complex. Through a Critical Interpretive Synthesis (CIS), this review explores the multidimensional role which educational settings hold in supporting children with SM. Key databases were searched (PsycInfo, British Education Index, Education Resources Information Center, British Library EThOS and Google Scholar) and a conceptual map, informed by experienced practitioners, guided additional purposive searching with a focus on conceptual saturation. A total of twenty-four papers were identified following a further process of appraisal. Reciprocal Translational Analysis (RTA) found that schools hold a tripartite role in supporting children with SM: this incorporated developing a shared understanding of the disorder, engaging in effective (and often multi-professional) planning, and offering direct support through adapting provision and facilitating individual intervention. Through realising this role, schools and educational settings might transform the support currently available for children and young people with SM. Implications for practice, policy and future research also emerged. This included a clear need for enhanced teacher understanding of SM, arguably at the level of initial teacher training (ITT).  相似文献   

Analogical reasoning in adolescents with intellectual disability: effects of external memories and time processing     

Caroline Denaes  Jean‐Louis Berger 《Journal of Research in Special Educational Needs》2014,14(2):82-95

Analogical reasoning involves the comparison of pictures as well as the memorisation of relations. Young children (4–7 years old) and students with moderate intellectual disability have a short memory span, which hampers them in succeeding traditional analogical tests. In the present study, we investigated if, by providing external memory hints, the visual aid could enable these participants to succeed in analogies comprising more relations than their memory span was able to manage. Our analogical test, composed of 2 × 2 matrices, was administered in two versions: the standard version, similar to traditional tests, required the participant to memorise all the relations involved in order to discover the solution, whereas the construction version required him/her to construct the answer part by part by using external memories, which potentially increased success by offloading the memory. Our results show that students with moderate intellectual disability reached results similar to typically developing control children when provided with external memory hints (referred to as external memories). Moreover, in the most complex levels of the test, they did not spend more time than control children in solving the analogies.  相似文献   

National Library of Medicine Classification User Group (UK) Immunology for librarians: report of a meeting held on 16 November 1983 at the Wellcome Institute for the History of Medicine     

Caroline Sheard 《Health information and libraries journal》1984,1(1):50-51

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Subjectivity and objectivity: Polanyi and Lonergan     

J. Fitzpatrick 《Higher Education Quarterly》1982,36(2):183-195

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Reviews and Update     

Giles Barrow  Susan Askew  Caroline Lodge 《Pastoral Care in Education》2003,21(3):30-33

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Global health database     

Fitzpatrick RB 《Medical reference services quarterly》2006,25(2):59-67

The Global Health database is available from Ovid Technologies, Inc., and also from CABI Publishing, EBSCO, and DataStar/ DIALOG. This database is really the combination of two others--the Public Health and Tropical Medicine database, formerly produced by the Bureau of Hygiene and Tropical Diseases, as well as human health and diseases information that is extracted from the CAB Abstracts database. This column will provide readers with an overview of the Global Health database, as well as present some searching hints. The Ovid interface will be used.  相似文献   

Comparison of Quebec and British teachers' beliefs about,training in and experience with attention deficit hyperactivity disorder     

Caroline Couture  Egide Royer  Franc¸ois A. Dupuis  Pierre Potvin 《Emotional and Behavioural Difficulties》2013,18(4):284-302

Abstract

This study compares belief patterns of teachers from Quebec and Britain about attention deficit hyperactivity disorder (ADHD). It also compares teacher training in ADHD in both countries, as well as their experience with students who have this disorder. The results indicate that: (1) teacher belief patterns about ADHD in Quebec and Britain are different, although teachers from both countries have predominant beliefs about ADHD that are of an allopathic medical nature; (2) British teachers have received less information on ADHD in their initial training than Quebec teachers; and (3) British teachers are contacted more often than Quebec teachers by doctors when they have a youngster using medication to treat ADHD in their classroom. Results are discussed from a sociological and an educational perspective.  相似文献   

A study of the difficulties of care and support in new university teachers’ work     

Caroline Walker  Alan Gleaves  John Grey 《Teachers and Teaching》2013,19(3):347-363

This paper discusses some findings from a small‐scale qualitative study involving ‘new’ teachers in a medium sized, regional English university. Using Grounded Theory methods to inform and guide the research, the study explores participants’ views on working as both teachers and researchers whilst also managing considerable amounts of ‘caring work’ with a diverse body of students who often need academic and pastoral support in excess of that assumed within the university academic timetables or support networks. The voices of these teachers suggest that care is an overlooked aspect of university teachers’ work, yet it plays an important part in maintaining their and their students’ sense of scholarly endeavour. Further, our findings suggest that within the university at large there is a ‘discourse of difference’ in the way that many academics conceptualize and represent the student body and students’ needs to be supported. This discourse impacts on the development of new teachers’ identities and aspirations. Some implications of these findings for implementing strategies for supporting teachers to develop both academic and pastoral roles within universities are discussed.  相似文献   

Imagining a different life in school: educating student teachers about ‘looked after’ children and young people     

Alan Walker‐Gleaves  Caroline Walker 《Teachers and Teaching》2013,19(5-6):465-479

The research described in this paper concerns the acquaintance of student teachers with the educational and wider pastoral experiences of children and young people who are or have been ‘looked after’ and who they may well teach at some point, together with the familiarisation of student teachers with the ‘looked after’ system in the UK. We discuss an exploratory awareness‐raising curriculum project within a Teacher Education Department at a University in the UK that utilises digital multimedia to develop a ‘community of awareness’ of young people and student teachers. As a result of this work, the student teachers were able to reflect on their pedagogical knowledge and practices related to teaching and wider pupil pastoral care. Further, those involved in the project therefore not only learned how to use technology, but to apply it in meaningful, productive ways, which were potentially transforming in terms of appreciation and knowledge of diversity. Benefits for the participants – the young people involved and the student teachers, as well as implications for both student teachers’ understanding of diversity and limitations of the technology – are discussed.  相似文献