Neuropsychology of Early-treated Phenylketonuria: Specific Executive Function Deficits   总被引：14，自引：0，他引：14  

Marilyn C. Welsh  Bruce F. Pennington  Sally Ozonoff  Bobbye Rouse  Edward R. B. McCabe 《Child development》1990,61(6):1697-1713

This study explored the hypothesis that children with early-treated phenylketonuria (PKU) are selectively impaired on executive function measures, even when still on diet. The rationale for this hypothesis is that even mild elevations in phenylalanine (Phe) can lead to lower central levels of biogenic amines, including dopamine (DA). We hypothesize that this mild DA depletion causes subtle prefrontal dysfunction, which in turn affects executive functions such as set maintenance, planning, and organized search. 11 preschool early-treated PKU children (M age = 4.64) and a sample of age- and IQ-matched unaffected peers (n = 11) were evaluated on a battery of executive function (EF) measures. In addition, a "non-executive function" task, recognition memory, was administered to all subjects. Group comparisons demonstrated that PKU children were significantly impaired on an executive function composite score; there were no group differences, however, in recognition memory. These results supported the hypothesized specific deficit in executive function. Furthermore, within the PKU group the executive function composite score was significantly negatively correlated with concurrent phenylalanine levels, even after controlling for the correlation between IQ and executive function skills. This second finding provides support for the proposed biochemical mechanism underlying the specific cognitive deficits.  相似文献   

Perspectives on pedagogical change: instructor and student experiences of a newly implemented undergraduate engineering dynamics curriculum*     

David Evenhouse  Nimit Patel  Maria Gerschutz  Nick A. Stites  Jeffrey F. Rhoads  Edward Berger 《European Journal of Engineering Education》2018,43(5):664-678

Engineering education has been slow to adopt research-based educational innovations. Few prior works on such adoption have investigated the combined classroom experiences of instructors and students when such innovations are being implemented. Therefore, this work focuses on the lived experiences of an instructor and her students when adopting an active, blended, and collaborative learning environment, known as Freeform, in a second-year dynamics course. Weekly reflections from the instructor were processed alongside student interviews using Thematic Analysis to discern prominent themes in their perspectives for comparison and discussion. The results indicate that the instructor navigated internal tensions between her previous instructional preferences and the philosophy and resources of Freeform. Similarly, students had to adapt to this new philosophy and suite of resources that were uncommon for their institution. Ultimately, this work highlights the contextual natures of teaching and learning, and how situational factors can influence educational innovation.  相似文献   

Peer victimization, poor academic achievement, and the link between childhood externalizing and internalizing problems     

van Lier PA  Vitaro F  Barker ED  Brendgen M  Tremblay RE  Boivin M 《Child development》2012,83(5):1775-1788

This study explored whether early elementary school aged children’s externalizing problems impede academic functioning and foster negative social experiences such as peer victimization, thereby making these children vulnerable for developing internalizing problems and possibly increasing their externalizing problems. It also explored whether early internalizing problems contributed to an increase in externalizing problems. The study examined 1,558 Canadian children from ages 6 to 8 years. Externalizing and internalizing problems, peer victimization, and school achievement were assessed annually. Externalizing problems lead to academic underachievement and experiences of peer victimization. Academic underachievement and peer victimization, in turn, predicted increases in internalizing problems and in externalizing problems. These pathways applied equally to boys and girls. No links from internalizing to externalizing problems were found.  相似文献   

Creating a mobile subject guide to improve access to point-of-care resources for medical students: a case study     

Boruff JT  Bilodeau E 《Journal of the Medical Library Association : JMLA》2012,100(1):55-60

  相似文献   

Effectiveness of a Science Agricultural Summer Experience (SASE) in Recruiting Students to Natural Resources Management     

Edward Martinez  Jennifer Lindline  Michael S. Petronis  Maura Pilotti 《Journal of Science Education and Technology》2012,21(6):713-721

The Bureau of Labor Statistics projects an increase in Natural Resource Management (NRM) jobs within the next 10?years due to baby-boomer retirements and a 12% increase in demand for these occupations. Despite this trend, college enrollment in NRM disciplines has declined. Even more critical is the fact that the soon-to-be-majority Hispanic population is underrepresented in NRM disciplines. The goal of the present study was to determine if an in-residence, two-week, summer science program for underrepresented minorities would not only increase interest in science, actual science knowledge, and perceived science knowledge, but also have an overall impact on underrepresented minority students?? decisions to attend college, major in a scientific discipline and pursue a career in science. During a four-year period, 76 high school students participated in a Science Agricultural Summer Experience (SASE) in Northern New Mexico. A pre/post science-knowledge exam and satisfaction survey were administered to participants. We demonstrate that participants improved significantly (p?<?.05) in all areas measured. In particular, comfort with science field and lab activities, science knowledge and perceived science knowledge were enhanced after exposure to the program. Students not only found science exciting and approachable after participation, but also exhibited increased interest in pursuing a degree and career in science. Of the 76 SASE participants within graduation age (n?=?44), all graduated from high school; and 86% enrolled in college. These findings suggest that the implemented SASE initiative was effective in recruiting and increasing the confidence and abilities of underrepresented minority students in science.  相似文献   

Variations on variability: effects of display composition on same–different discrimination in pigeons     

Leyre Castro  Edward A. Wasserman  Michael E. Young 《Learning & behavior》2012,40(4):416-426

Discriminating same from different multiitem arrays can be represented as a discrimination between arrays involving low variability and arrays involving high variability. In the present investigation, we first trained pigeons with the extreme values along the variability continuum (arrays containing 16 identical items vs. 16 nonidentical items), and we later tested the birds with arrays involving intermediate levels of variability; we created these testing arrays either by manipulating the combination of same and different items (mixture testing) or by changing the number of items in the same and different arrays (number testing). According to an entropy account (Young & Wasserman, Journal of Experimental Psychology: Animal Behavior Processes 23:157?C170, 1997), the particular means of changing variability should have no effect on same?Cdifferent discrimination performance: Equivalent variability should yield equivalent performance. In this critical test of an entropy account, we found that entropy could explain a large portion of our data, but not the entire collection of results.  相似文献   

It’s a Profane Life: Giorgio Agamben on the freedom of im-potentiality in education     

Tyson Edward Lewis 《Educational Philosophy and Theory》2014,46(4):334-347

Abstract

In this article, I explore the importance of Giorgio Agamben’s theory of potentiality for rethinking education. While potentiality has been a long-standing concern for educational practitioners and theorists, Agamben’s work is unique in that it emphasizes how potentiality can only be thought of in relation to impotentiality. This moment of indistinction—what I refer to as im-potential—has important implications. First, I argue that if potentiality and impotentiality are separated from one another, the result is a stratified educational system where some students are commanded to actualize their potentiality in the form of standardized tests while others are abandoned by the system. Second, thinking im-potentiality enables us to move beyond problematic formulations of learning and rediscover the uniqueness of studying. Here, I offer a brief example of study through an analysis of ‘Tinkering Schools’, an alternative program founded by Gever Tulley in San Francisco. And finally, without a concept of im-potentiality, the discourse of the ‘child genius’ becomes commodified as a power to be harnessed and actualized in the name of neoliberal entrepreneurialism. Only through a return to im-potentiality can we reclaim Genius and its relationship to the question of educational freedom.  相似文献   

II. PHYSICAL ACTIVITY: MEASUREMENT AND BEHAVIORAL PATTERNS IN CHILDREN AND YOUTH     

Thomas R. Wójcicki  Edward McAuley 《Monographs of the Society for Research in Child Development》2014,79(4):7-24

  相似文献   

Mass Media     

Daniel N. Lapedes  James W. Brown  Henry Geller  Edward M. Dickson  Raymond Bowers  Martin H. Seiden 《Communication Booknotes Quarterly》2013,44(5):59-63

Robert C. Toll's On with the Show: The First Century of Show Business in America (New York: Oxford University Press, 1976---$19.95)

Edwin Fisher, et al., eds. The Art in Cartooning: Seventy-five Years of American Magazine Cartoons (New York : Scribner's, 1975---$14.95)

Vaughncille Molden's Telecommunications and Black Americans: A Survey of Ownership, Participation and Control (Center for Development Technology and Program in Technology and Human Affairs, Washington University, St. Louis, Mo. 63130-48.50, paper)

Working Papers in Culture and Communication (Department of Anthropology, Temple University, Philadelphia, Pa. 19122-- $2.00, paper)  相似文献   

Motion Pictures     

Christian Metz  Ernest D. Rose  Walter E. Hurst  William Storm Hale  Edward Murray  Douglas Brode 《Communication Booknotes Quarterly》2013,44(8):94-96

Richard Bunce's Television in the Corporate Interest (New York: Praeger Special Studies, 1976—price not given, but about $15.00).

Ralph M. Jennings and Veronica M. Jefferson's Television Station Employment Practices, 1975: The Status of Minorities and Women (New York: Office of Communication, United Church of Christ, 1976—price not given, but about $10.00, paper)

Horace Newcomb's Television: The Critical View (New York: Oxford University Press, 1976—$4.00, paper)

Asa Berger's The TV-Guided American (New York: Walker, 1976—$8.95)

Vincent Mosco's The Regulation of Innovations in the Broadcasting Market (Cambridge, Mass.: Harvard University Program on Information Technologies and Public Policy, 1975—$3.00, paper)

James D. Scott's Cable Television: Strategy for Penetrating Key Urban Markets (Ann Arbor: University of Michigan Graduate School of Business Administration, 1976—$5.50, paper)

R.W. Chandler's Sparks at Sea: The Experiences of a Ship's Radio Officer (North Pomfret, Vt.: David and Charles, 1973, but only recently released in the U.S.—$9.50)  相似文献