高校思想政治理论课灌输教学法创新之探究     

何独明 《辽宁教育行政学院学报》2010,27(3):52-54

灌输教学法是高校思想政治理论课教学的重要方法之一.在高校思想政治理论课教学中要坡灌输教学法保持其有效性,就要从灌输的载体、方法方面进行创新,显性灌输教学法与臆性渗透教学法相结合;理论灌输法与启发法相结合;理论灌输法与大学生自我教育法相结合;大力提升教师的素质等.  相似文献   

汉语“吃”字系列的古今词义演变     

吕鹤 《鸡西大学学报》2010,10(5):127-128

吃东西人人都会,＂吃＂的规矩却不一定人人明白;＂吃＂字人人会写,＂吃＂字的由来却不一定人人知道。其根源和规矩也并不是从一开始就有,而是经历了漫长的时间才形成的。＂吃＂发展到一定程度,已经不只是一种生存行为,而是变成了一种文化。  相似文献   

新升本院校公共选修课存在的问题及对策     

王国强 《时代教育》2010,(7):61-62

新升本院校的公共选修课中较为普遍地存在着认识不足、资源缺乏和监管不力等问题,解决这些问题需要在加强宣传,探索最大化利用有限资源的政策和加强总体规划与监管等三个方面下功夫.  相似文献   

从对比分析角度浅析对泰汉语语音教学策略     

何山燕 《梧州学院学报》2010,20(4)

泰国汉语学习者学习汉语语音的难点主要体现为泰语语音系统中空缺以及某些具有相似性但存在差别的语音要素.该文从声母、韵母与声调三个层面对汉语、泰语语音系统加以对比分析,探讨对泰语音教学的微观策略.  相似文献   

桂北高师公共民族音乐教育学前调查——广西高师中国民族音乐教育教学探索与实践之五     

何政荣 《贺州学院学报》2010,26(4)

素质教育在中国已经实施了20多年.1999年,国家颁布了<关于深化教育改革、全面推进素质育教的决定>,强调建设高质量的教师队伍和全面实施艺术教育的重要性.广西师范大学公共民族音乐课程<中国民族民间音乐欣赏与实践>是非音乐专业学生学前音乐基础课程.中国各级教育管理者和美育工作者研究它,可以反思、探讨广西及其他省市中小学音乐素质教育实施情况,了解其对高师公共音乐教育、民族音乐教育实施影响的情况.  相似文献   

Effect of interrupted endogenous BMP/Smad signaling on growth and steroidogenesis of porcine granulosa cells     

Wei Wang  Li Wang  Xin-xiu Li  Xia Chen  Hai-yan Zhang  Yu He  Jing-jing Wang  Yong-yan Zhao  Bao-le Zhang  Yin-xue Xu 《Journal of Zhejiang University. Science. B》2010,11(9):719-727

Bone morphogenetic proteins (BMPs) play a critical role in the growth and steroidogenesis of granulosa cells (GCs). BMP signals act through membrane-bound heteromeric serine/threonine kinase receptors. Upon ligand binding, BMPs activate intracellular Smad proteins and regulate growth and apoptosis in various cell types. The objective of this study was to demonstrate the effects of BMP/Smad signal on growth and steroidogenesis of porcine GCs. A strategy of RNA interference (RNAi)-mediated ‘gene silencing’ of Smad4, a core molecule mediating the intracellular BMP/Smad signal transduction pathways, was used to interrupt endogenous BMP/Smad signaling. Results indicate that Smad4-small interfering RNA (siRNA) caused specific inhibition of Smad4 mRNA and protein expression after transfection. Interrupted endogenous BMP/Smad signaling significantly inhibited growth, and induced apoptosis of porcine GCs, while decreasing estradiol production. In addition, interrupted BMP/Smad signaling significantly (P<0.05) changed the expression of Cyclin D2, CDK4, Bcl-2, and Cyp19a1. These findings provide new insights into how BMP/Smad signaling regulates the growth and steroidogenesis of porcine GCs.  相似文献   

Sevoflurane postconditioning reduces myocardial reperfusion injury in rat isolated hearts via activation of PI3K/Akt signaling and modulation of Bcl-2 family proteins     

Li-na Yu  Jing Yu  Feng-jiang Zhang  Mei-juan Yang  Ting-ting Ding  Jun-kuan Wang  Wei He  Tao Fang  Gang Chen  Min Yan 《Journal of Zhejiang University. Science. B》2010,11(9):661-672

Sevoflurane postconditioning reduces myocardial infarct size.The objective of this study was to examine the role of the phosphatidylinositol-3-kinase(PI3K)/Akt pathway in anesthetic postconditioning and to determine whether PI3K/Akt signaling modulates the expression of pro-and antiapoptotic proteins in sevoflurane postconditioning.Isolated and perfused rat hearts were prepared first,and then randomly assigned to the following groups:Sham-operation(Sham),ischemia/reperfusion(Con),sevoflurane postconditioning(SPC),Sham plus 100 nmol/L wortmannin(Sham+Wort),Con+Wort,SPC+Wort,and Con+dimethylsulphoxide(DMSO).Sevoflurane postconditioning was induced by administration of sevoflurane(2.5%,v/v) for 10 min from the onset of reperfusion.Left ventricular developed pressure(LVDP),left ventricular end-diastolic pressure(LVEDP),maximum increase in rate of LVDP(+dP/dt),maximum decrease in rate of LVDP(?dP/dt),heart rate(HR),and coronary flow(CF) were measured at baseline,R30 min(30 min of reperfusion),R60 min,R90 min,and R120 min.Creatine kinase(CK) and lactate dehydrogenase(LDH) were measured after 5 min and 10 min reperfusion.Infarct size was determined by triphenyltetrazolium chloride staining at the end of reperfusion.Total Akt and phosphorylated Akt(phospho-Akt),Bax,Bcl-2,Bad,and phospho-Bad were determined by Western blot analysis.Analysis of variance(ANOVA) and Student-Newman-Keuls' test were used to investigate the significance of differences between groups.The LVDP,±dP/dt,and CF were higher and LVEDP was lower in the SPC group than in the Con group at all points of reperfusion(P0.05).The SPC group had significantly reduced CK and LDH release and decreased infarct size compared with the Con group [(22.9±8)% vs.(42.4±9.4)%,respectively;P0.05].The SPC group also had increased the expression of phospho-Akt,Bcl-2,and phospho-Bad,and decreased the expression of Bax.Wortmannin abolished the cardioprotection of sevoflurane postconditioning.Sevoflurane postconditioning may protect the isolated rat heart.Activation of PI3K and modulation of the expression of pro-and antiapoptotic proteins may play an important role in sevoflurane-induced myocardial protection.  相似文献   

安顺市“十二·五”期间人才开发的对策     

贺明达  冯开禹  颜丙震 《安顺学院学报》2010,(6):74-77

加强对安顺市"十二·五"期间人才开发的研究力度,通过对人才开发面临的问题及人才需求状况的分析,提出相应的对策措施,对于制定安顺市"十二.五"人才发展规划和安顺市"十二·五"经济社会发展规划,更好地实施人才强市战略,加强对人才的吸引、培养和使用,充分发挥好人才的作用,具有重要的指导意义。  相似文献   

以案例促进《概率论与数理统计》教学     

于涛  刘鹤  董艳 《中国科教创新导刊》2010,(5):80-80

本文是有关案例教学法对《概率论与数理统计》教学提升作用的研究,列举了三个应用在教学中案例,讨论了案例与相应知识点结合的问题,为改善《概率论与数理统计》的教学效果作了一些教学创新。  相似文献   

福建省田径裁判工作特点的探析——以第十三届省运会田径比赛为例     

李长沙  廖金琳  林锦福 《赤峰学院学报(自然科学版)》2010,26(8):100-102

文章通过文献资料法、专家访谈法和归纳演绎法等研究方法对福建省第13届运动会田径比赛裁判工作的特点进行分析,认为：高科技的计算机网络系统与合理的应用电子信号是该次赛事的特色;融培训、评价、考核为一体的裁判人才管理体系是赛事圆满完成的重要保障．  相似文献