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Biljak VR Ozvald I Radeljak A Majdenic K Lasic B Siftar Z Lovrencic MV Flegar-Mestric Z 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(1):86-91
Introduction
The aim of the study was to present a protocol for laboratory information system (LIS) and hospital information system (HIS) validation at the Institute of Clinical Chemistry and Laboratory Medicine of the Merkur University Hospital, Zagreb, Croatia.Materials and methods:
Validity of data traceability was checked by entering all test requests for virtual patient into HIS/LIS and printing corresponding barcoded labels that provided laboratory analyzers with the information on requested tests. The original printouts of the test results from laboratory analyzer(s) were compared with the data obtained from LIS and entered into the provided template. Transfer of data from LIS to HIS was examined by requesting all tests in HIS and creating real data in a finding generated in LIS. Data obtained from LIS and HIS were entered into a corresponding template. The main outcome measure was the accuracy of transfer obtained from laboratory analyzers and results transferred from LIS and HIS expressed as percentage (%).Results:
The accuracy of data transfer from laboratory analyzers to LIS was 99.5% and of that from LIS to HIS 100%.Conclusion:
We presented our established validation protocol for laboratory information system and demonstrated that a system meets its intended purpose. 相似文献24.
The bystander effect in cancer therapy is the inhibition or killing of tumor cells that are adjacent to those directly affected by the agent used for treatment. In the case of chemotherapy, little is known as to how much and by which mechanisms bystander effects contribute to the elimination of tumor cells. This is mainly due to the difficulty to distinguish between targeted and bystander cells since both are exposed to the pharmaceutical compound. We here studied the interaction of tamoxifen-treated human breast cancer MCF-7 cells with their neighboring counterparts by exploiting laminar flow patterning in a microfluidic chip to ensure selective drug delivery. The spatio-temporal evolution of the bystander response in non-targeted cells was analyzed by measuring the mitochondrial membrane potential under conditions of free diffusion. Our data show that the bystander response is detectable as early as 1 hour after drug treatment and reached effective distances of at least 2.8 mm. Furthermore, the bystander effect was merely dependent on diffusible factors rather than cell contact-dependent signaling. Taken together, our study illustrates that this microfluidic approach is a promising tool for screening and optimization of putative chemotherapeutic drugs to maximize the bystander response in cancer therapy. 相似文献
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In 1996, Acadia University became the first Canadian university to adopt a plan of a fully computerized campus. This plan called for progressively equipping each student and faculty member with a personal laptop computer, introducing computer technology into most courses, providing students and faculty with ubiquitous access to the computer network everywhere on the campus, and integrating the technology into the undergraduate curriculum and campus life. In this paper, we describe the context in which this decision was made, discuss the nature of the experience and the involvement of faculty and students in the process, the logistic problems, and impact on faculty and students, successes and disappointments. We also present selected research projects undertaken by faculty within this framework, and outline plans for the future. 相似文献
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Mauro Ivan Peña 《Community College Journal of Research & Practice》2013,37(3):186-200
ABSTRACTA qualitative case study approach was used to examine Latino male students and First-Year Experience (FYE) programs aimed at promoting student transfer. Two FYE programs at two community colleges in California were studied: Bridgetown Community College and Portlake Community College (pseudonyms). Study participants included four groups: Latino male FYE students, Latino male FYE alumni, FYE counselors, and FYE coordinators. Data collection strategies included semi-structured interviews, site observations, and document analysis. Analysis of data involved both deductive and inductive approaches, and resulted in identification of four findings critical to the success of FYE programs and their work with Latino males: (a) the need to support help-seeking behaviors, (b) the need to address the “long journey” to transfer, (c) the need to support students’ work burden and financial constraints, and (d) the need to incorporate approachable and culturally responsive practices. Overall, the study offers insights into how community colleges might strengthen transfer support for Latino males through FYE programs. 相似文献
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