塞外承德曾是龚自珍理想的归隐之地     

关阔 《承德师专学报》2006,26(3):9-10

一位旷代天才,国士无双的龚自珍,世代簪缨．出生在人间天堂杭州。果真对塞北小山城的承德情有独钟吗?  相似文献   

Modulating chemotaxis of lung cancer cells by using electric fields in a microfluidic device     

Yu-Chiu Kao  Meng-Hua Hsieh  Chung-Chun Liu  Huei-Jyuan Pan  Wei-Yu Liao  Ji-Yen Cheng  Po-Ling Kuo  Chau-Hwang Lee 《Biomicrofluidics》2014,8(2)

We employed direct-current electric fields (dcEFs) to modulate the chemotaxis of lung cancer cells in a microfluidic cell culture device that incorporates both stable concentration gradients and dcEFs. We found that the chemotaxis induced by a 0.5 μM/mm concentration gradient of epidermal growth factor can be nearly compensated by a 360 mV/mm dcEF. When the effect of chemical stimulation was balanced by the electrical drive, the cells migrated randomly, and the path lengths were largely reduced. We also demonstrated electrically modulated chemotaxis of two types of lung cancer cells with opposite directions of electrotaxis in this device.  相似文献   

Therapeutic potential of traditional Chinese medicine for vascular endothelial growth factor     

Yijia MAO  Lingkai MENG  Huayi LIU  Yuting LU  Kuo YANG  Guangze OUYANG  Yanran BAN  Shuang CHEN 《Journal of Zhejiang University. Science. B》2022,23(5):353

Vascular endothelial growth factor (VEGF) is the main regulator of physiological angiogenesis during embryonic development, bone growth, and reproductive function, and it also participates in a series of pathological changes. Traditional Chinese medicine (TCM), with a history of more than 2000 years, has been widely used in clinical practice, while the exploration of its mechanisms has only begun. This review summarizes the research of recent years on the influence of TCM on VEGF. It is found that many Chinese medicines and recipes have a regulatory effect on VEGF, indicating that Chinese medicine has broad prospects as a complementary and alternative therapy, providing new treatment ideas for clinical applications and the theoretical basis for research on the mechanisms of TCM.  相似文献