药品开发主体分析          下载免费PDF全文

治部真里  李颖 《情报工程》2015,1(2):008-020

日本版NIH及其制药企业,政策制定·战略规划需要佐证。本研究尝试基于新的指标体系进行制药产业的现状俯瞰与预测未来。连载第三篇着眼于持有在研药物(pipeline)主体的规模及其种类,分析了掌控医药品开发的关键主体。其结果表明美国的强项在于中小企业与创业企业。另一方面,日本中小企业与创业企业没有承担像美国那样的角色。  相似文献   

基于在研药物相关专利判别指标分析药物开发的基础研究状况          下载免费PDF全文

治部真里  李颖  曾文 《情报工程》2015,1(3):008-018

日本版NIH 及其制药企业,政策制定·战略规划需要佐证。为此,本研究尝试基于新的指标体系进行制药行业的现状俯瞰与未来预测。本篇基于连载第四篇导出的用于辨识制药企业在研药物及药物密切相关专利的新指标,按照国别和专利申请人,揭示低分子药物、不同技术类别的生物药的基础研究能力。  相似文献   

The Joinville School and the Institutionalization of a French-Style Physical Education, 1852–1939     

Jean Saint-Martin  Michaël Attali 《国际体育史杂志》2015,32(6):740-753

Since the mid-nineteenth century, the Joinville School in France has worked to promote an innovative method of physical education, the French method, which was strongly marked by ideological and geopolitical challenges. Most of the French actors, whether they be military, doctors, scientists, or teachers, fought to defend France on the move. Physical education and its scholastic responsibility thus represented an original means to serve the national community and to give the country the necessary influence it required on the political and cultural international scene. If during the Second Empire, the Joinville School participated in the development of the physical instruction of French troops, during the third Republic, this officers' training school expanded the promotion of its method for physical education in schools. Among the challenges of this strategy, the actors for French physical education were faced with the organization of a common national teaching method as additional support for the promotion of a method that bore the mark of an eclectic philosophy. Until World War II, the Joinville School was a center for innovation that would spread practical physical education throughout France and Europe.  相似文献   

对外汉语口语教学中面临的问题及思考     

孔凡洁 《河北广播电视大学学报》2014,19(5):81-84

分析当前对外汉语口语课所肩负的任务,以及其中所存在的问题。某些口语课依然存在以讲授语言点为重点,而不是侧重语言技能的训练。教学进度与练习时间冲突。在语言环境不够真实的情况下,教学方法又太过传统。在教学实践中,各任课教师集体备课,协调词汇语法教学任务。以及走出课堂,充分利用学校和社会语言环境等方法对提高口语课的实效都很有帮助。  相似文献   

Current Developments in Community College Performance Funding     

Mark M. D'Amico  Janice N. Friedel  Stephen G. Katsinas  Zoë M. Thornton 《Community College Journal of Research & Practice》2014,38(2-3):231-241

Since the initiation of performance funding in Tennessee in the late 1970s, approximately 30 states have, at some point, attempted a funding model that includes performance on a set of indicators. The purpose of the present study was to capture the current status of performance funding in public statewide community college systems and to assess which performance indicators were collected at the state level. Data were obtained through the 2012 Survey of Finance and Access Issues conducted by the Education Policy Center at the University of Alabama. The survey was administered to the National Council of State Directors of Community Colleges, and 50 responses were obtained from 49 states. Not every survey respondent answered each survey item. Findings showed that 19 states used performance funding for community colleges, with six of those states allocating at least 10% of state funds based on performance. An analysis of indicators captured at the state level (not exclusively for performance funding) showed a decline of emphasis on process indicators and greater emphasis on outputs. The performance-based distribution of base funding and the inclusion of output measures that capture intermediate indicators of success are consistent with the principles of Performance Funding 2.0, a new form of performance funding recently discussed in the literature. Future research should include tracking the current findings over time and expanding the existing literature on whether performance funding influences outcomes.  相似文献   

Separation of platelets from other blood cells in continuous-flow by dielectrophoresis field-flow-fractionation     

Piacentini N  Mernier G  Tornay R  Renaud P 《Biomicrofluidics》2011,5(3):34122-341228

We present a microfluidic device capable of separating platelets from other blood cells in continuous flow using dielectrophoresis field-flow-fractionation. The use of hydrodynamic focusing in combination with the application of a dielectrophoretic force allows the separation of platelets from red blood cells due to their size difference. The theoretical cell trajectory has been calculated by numerical simulations of the electrical field and flow speed, and is in agreement with the experimental results. The proposed device uses the so-called "liquid electrodes" design and can be used with low applied voltages, as low as 10 V(pp). The obtained separation is very efficient, the device being able to achieve a very high purity of platelets of 98.8% with less than 2% cell loss. Its low-voltage operation makes it particularly suitable for point-of-care applications. It could further be used for the separation of other cell types based on their size difference, as well as in combination with other sorting techniques to separate multiple cell populations from each other.  相似文献   

The harmful aspect of teacher conditional support on students’ self-perception of school competence     

Marine Hascoët  Pascal Pansu  Thèrèse Bouffard  Nadia Leroy 《European Journal of Psychology of Education - EJPE》2018,33(4):615-628

When children perceive a conditional support, they only feel loved and encouraged for their ability to meet others’ standards. This may lead them to develop high sensitivity to errors and anxiety and low perception of competence. In this study, we examined the relationship between the perceived conditional support from teacher and children’s self-perception of school competence. We tested the mediating effect of sensitivity to errors and test anxiety in the relationship between teacher conditional support and children’s perception of school competence. Participants were 524 elementary school students (aged 9–10 years). The results showed that the greater the extent to which the children perceived conditional support from their teacher, the lower their self-perceived scholastic competence. They also confirm that this relationship was mediated by sensitivity to errors and test anxiety.  相似文献   

Etude en temps réel de la production eEcrite chez des enfants de sept et huit ans     

Jean-Noël Foulin  Michel Fayol 《European Journal of Psychology of Education - EJPE》1988,3(4):461-475

The aim of this research is to study on-line written production in children. Twelve seven year old children and twelve eight year old children were asked to compose two texts (a narrative and a report). They were filmed as they wrote in order to investigate the temporal caracteristics of their composition (pauses, rates…). The results show three main findings:

- the rates increases from seven to eight year old.

- pauses times varied according to the syntactic organisation of the next sentence.

- longer pause times are localized after punctuation marks and before connective.

  相似文献   

“Digging for Gold” or “Sticking to the Criteria”: Teachers’ Rationales When Serving as Professional Raters     

Lennart Jølle 《Scandinavian Journal of Educational Research》2020,64(2):283-299

ABSTRACT

This paper reports findings from a project called “The National Panel of Raters” (NPR) that took place within a writing test programme in Norway (2010–2016). A recent research project found individual differences between the raters in the NPR. This paper reports results from an explorative follow up-study where 63 NPR members were surveyed with 23 items that were dilemma-like in the sense that deviating from the NPR rules would follow another—but socially acceptable—rationale. Four NPR members participated in a follow-up interview in which they motivated why they had agreed or disagreed with certain items. The results indicate two distinctly different stances toward rating work, with one stance threatening the validity of the scoring process.  相似文献   

Facebook group dynamics: an ethnographic study of the teaching and learning potential for secondary school teachers     

Jaël Muls  Karen Triquet  Joachim Vlieghe  Free De Backer  Chang Zhu  Koen Lombaerts 《Learning, Media and Technology》2019,44(2):162-179

ABSTRACT

This study examines the role of social networking sites on the learning processes, teaching practices and professional development of secondary school teachers. By conducting observations and in-depth interviews with active participants, we present an ethnographic study of the Facebook group Teaching ideas secondary education [author’s translation], which is hosted and primarily employed by Flemish teachers. By drawing parallels between the study findings and the theory of affinity spaces we aim to gain greater insight into emerging group dynamics and social informal learning processes. According to respondents, the Facebook group has the potential to address teachers’ needs with respect to the exchange of teaching ideas, experiences and materials. The findings point to a number of emerging developments in the educational landscape, highlighting that social media environments present a new source of inspiration, and combined with a collaborative atmosphere are able to stimulate cross-fertilization, social informal learning processes and self-management and -reflection. We hold these findings up to the light of current education discourses.  相似文献