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71.

Objective:

The objective of this study was to validate an assessment instrument for MEDLINE search strategies at an academic medical center.

Method:

Two approaches were used to investigate if the search assessment tool could capture performance differences in search strategy construction. First, data from an evaluation of MEDLINE searches from a pediatric resident''s longitudinal assessment were investigated. Second, a cross-section of search strategies from residents in one incoming class was compared with strategies of residents graduating a year later. MEDLINE search strategies formulated by faculty who had been identified as having search expertise were used as a gold standard comparison. Participants were presented with a clinical scenario and asked to identify the search question and conduct a MEDLINE search. Two librarians rated the blinded search strategies.

Results:

Search strategy scores were significantly higher for residents who received training than the comparison group with no training. There was no significant difference in search strategy scores between senior residents who received training and faculty experts.

Conclusion:

The results provide evidence for the validity of the instrument to evaluate MEDLINE search strategies. This assessment tool can measure improvements in information-seeking skills and provide data to fulfill Accreditation Council for Graduate Medical Education competencies.

Highlights

  • The University of Michigan MEDLINE Search Assessment tool can be used to assess search skills in residency education.
  • Five elements were identified as critical elements in the development of an effective MEDLINE search strategy: inclusion of all search concepts, appropriate use of Medical Subject Headings, appropriate use of search limits, successful combination of all concepts, and search efficiency.

Implications

  • This validated assessment tool can serve as an effective means to measure improvements in residents'' information-seeking skills and provide data to fulfill Accreditation Council for Graduate Medical Education competencies.
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Early Childhood Education Journal - Children benefit from strong home–school relationships. Yet, parents who are immigrants and refugees are expected to follow frameworks for school...  相似文献   
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Obesity rates among preschool-aged children have doubled in the past 10 years, and 60 % of these children spend the majority of their day in childcare facilities. Few studies have examined the quality of nutrition and physical activity practices in childcare centers as compared to family childcare homes. The purpose of this study is to determine if a pattern of differences exist in these two settings. As part of a CDC-funded study to reduce the obesity epidemic in young children, directors of 1,140 childcare facilities (842 out-of-home and 298 in-home) in one large county completed a survey that detailed their practices related to child nutrition and physical activity. Results showed that compared with out-of-home facilities, in-home facilities were more likely to report excellent indoor physical activity (87.2 vs. 85.5 %, p = 0.059), less likely to report excellent outdoor physical activity (92.8 vs. 96.5 %, p = 0.018), more likely to serve fruit (80.3 vs. 51.2 %), and less likely to serve 1 % milk (45.2 vs. 55 %). This study’s present findings revealed that ample opportunity exists to significantly improve the health of young children in both in-home and out-of-home facilities.  相似文献   
75.
How do students draw on texts read in class to explore and make sense of the world? How does role-play open up the possibilities of utilising these resources, remaking them for their own purposes? How does play, as Vygotsky suggests, enable students to achieve more? And how does being in role change the character of social relations in the classroom, enabling students to shed new light on their lives, their experiences. This essay focuses close attention on two role-plays, both involving the same pair of 11th-grade students from a school in Ramallah. The role-plays arose out of, and enabled the students to explore, literary texts that they had been studying in class: Ibsen’s A Doll’s House and Steinbeck’s Of Mice and Men. The article argues that what the students accomplished in this work is complex and needs to be understood in context. Through this account, the essay seeks to challenge those (currently fashionable) models of pedagogy that are insufficiently attentive to the histories, identities and interests of particular learners.  相似文献   
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The majority of eukaryotic genes produce multiple mRNA isoforms with distinct 3′ ends through a process called mRNA alternative polyadenylation (APA). Recent studies have demonstrated that APA is dynamically regulated during development and in response to environmental stimuli. A number of mechanisms have been described for APA regulation. In this review, we attempt to integrate all the known mechanisms into a unified model. This model not only explains most of previous results, but also provides testable predictions that will improve our understanding of the mechanistic details of APA regulation. Finally, we briefly discuss the known and putative functions of APA regulation.  相似文献   
77.
The oil painting “La Medusa” executed by Caravaggio at the end of the XVI century on a wooden shield, was investigated by integrated physical–chemical and analytical methodologies in order to obtain scientific data capable of elucidating the state of conservation and the painting technique. Optical (OM) and electronic (SEM-EDS) microscopy, micro-FT-IR spectroscopy, gas chromatography–mass spectrometry (GC–MS) and pyrolysis GC–MS were applied on two microfragments and some organic samples obtained by solvent extraction using the swab cleaning technique. The obtained results indicated that Caravaggio probably reused an old shield as a previous gypsum preparation layer has been detected under the original painting layers. He used white lead, natural earths, verdigris and lead–tin yellow type I mixed with drying oils to paint. The considerable amount of amorphous particles of copper chlorides found in the green pigment verdigris suggests that it could have been produced according to the ancient recipe of verde salsum described by Theophilus. Mordant gilding has been identified on the upper part of the shield that can be related to an abandoned experiment to give the painting a mirror-like reflecting effect. Three different varnishes layers have been detected above the painted surface. The original and restoration varnishes have been identified and they contain a mixture of drying oil, mastic and turpentine and some beeswax. Cleaning tests, performed with different organic solvents, suggest the use of isopropyl alcohol as cleaning agent because it is less efficient in comparison to others solvents; thus it ensures a careful and controlled removal of the varnishes.  相似文献   
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