排序方式： 共有70条查询结果，搜索用时 15 毫秒
51.
52.
53.
A 3D predictive golfer model can be a valuable tool for investigating the golf swing and designing new clubs. A forward dynamic model, which includes a four degree of freedom golfer model, a flexible shaft based on Rayleigh beam theory, an impulse-momentum impact model and a spin rate dependent aerodynamic ball model, is presented. The input torques for the golfer model are provided by parameterized joint torque generators that have been designed to mimic muscle torque production. These joint torques are optimized to create swings and launch conditions that maximize carry distance. The flexible shaft model allows for continuous bending in the transverse directions, axial twisting of the club and variable shaft stiffness as a function of the length. The completed four-part model with the default parameters is used to estimate the ball carry of a golf swing using a particular club. This model will be useful for experimenting with club design parameters to predict their effect on the ball trajectory and carry distance. 相似文献
54.
Pallavi Amitava Banerjee 《牛津教育评论》2017,43(1):1-18
Science, technology, engineering, and mathematics (STEM) skills are very valuable for economic growth. However, the number of young people pursuing STEM learning trajectories in the United Kingdom was lower than the predicted demand during the last decade. Several STEM enrichment and enhancement activities were thus funded by the government, private, and charitable organisations to improve understanding of and raise pupil interest in these subjects. One possible way of measuring the impact of these activities in supporting pupil understanding of maths was to track the proportion of young people obtaining a ‘good’ grade in standardised national tests such as the GCSEs. Attainment is of course only one possible outcome of education but certainly a very important one because students are more likely to continue studying subjects in which they score higher. This makes maths attainment even more important as it is a pre-requisite for admission to STEM degree courses. This longitudinal study makes use of the National Pupil Database to assess the impact of these schemes on maths attainment of participating schools. Following up 300 intervention schools for five years the study shows the intervention group did not do any better than the comparator. The paper suggests further directions for research and offers recommendations for practice. 相似文献
55.
M. Banerjee S. Bhattacharyya C. Das 《Indian journal of clinical biochemistry : IJCB》1999,14(1):19-25
A simple, highly sensitive, direct, competitive ELISA for human serum testosterone has been indigenously developed. Specific
antisera against testosterone were raised in rabbits using testosterone—3carboxymethyl oxime (CMO)—bovine serum albumin (BSA)
as the antigen. For the enzyme conjugate, testoterone—3CMO was coupled with horse raddish peroxidase by the active ester method.
The standard curve covered a wide range from 3.9 pg/ml to 500 pg/ml. The inter and intra-assay variation were found to be
low and within the acceptable limits. Specificity and accuracy for the assay was established by having negligible crossreactivity
with the related steroids and an excellent parallelism between the sample and standard dilution curve. Samples measured by
RIA and ELISA showed very high degree of correlation (r=0.991). 相似文献
56.
57.
Application of Tucatinib and Trastuzumab: Dual Anti HER2 Therapy Against HER2 Positive Breast Cancer
Sumanpreet Kaur Rajasri Bhattacharyya Dibyajyoti Banerjee Jaya Shukla 《Indian journal of clinical biochemistry : IJCB》2021,36(1):124
Synergism in action of tucatinib and trastumab is reported in breast cancer management. However, its molecular basis is yet to be determined. In this context we attempted to provide an explanation at the molecular level by performing in silico experimentation and coupling its result with already available published observations. Our study will provide basis for planning further experimental study for unravelling the truth. 相似文献
58.
59.
Disha Banerjee Debarati Ghosh Anindita Chatterjee Swagata Sinha Krishnadas Nandagopal 《Indian journal of clinical biochemistry : IJCB》2012,27(1):46-51
GARS–AIRS–GART is crucial in studies of Down syndrome (DS)-related mental retardation due to its chromosomal location (21q22.1), involvement
in de novo purine biosynthesis and over-expression in fetal DS brain postmortem samples. GARS–AIRS–GART regions important for structure–function were screened for mutations that might alter protein levels in DS patients. Mutation
screening relied on multiplex/singleplex PCR-based amplification of genomic targets followed by amplicon size determination/fingerprinting.
Serum protein samples were resolved by SDS-PAGE and immunoblotted with a GARS–AIRS–GART monoclonal antibody. No variation
in amplicon size/fingerprints was observed in regions encoding the ATP-binding, active site residues of GARS, the structurally
important glycine-rich loops of AIRS, substrate-binding, flexible and folate-binding loops of GART or the poly-adenylation
signal sequences. The de novo occurrence or inheritance of large insertion/deletion/rearrangement-type mutations is therefore
excluded. Immunoblots show presence of GARS–AIRS–GART protein in all patient samples, with no change in expression levels
with respect to either sex or developmental age. 相似文献
60.