Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis     

Xiaocui Xu  Guoqiang Li  Congru Li  Jing Zhang  Qiang Wang  David K Simmons  Xuepeng Chen  Naveen Wijesena  Wei Zhu  Zhanyang Wang  Zhenhua Wang  Bao Ju  Weimin Ci  Xuemei Lu  Daqi Yu  Qian-fei Wang  Neelakanteswar Aluru  Paola Oliveri  Yong E Zhang  Mark Q Martindale  Jiang Liu 《国家科学评论(英文版)》2019,6(5):993

  相似文献   

Are we promoting critical autonomous thinking? A discussion on conversational genres and whether they can help us answer this question     

Andrés Mejía  Adriana Molina 《Cambridge Journal of Education》2007,37(3):409-426

This work is based on the assumption that if the classroom is a space in which manifestations of critical autonomous thinking appear systematically, then it promotes that same kind of thinking by the students, in other contexts. But what count as manifestations of critical autonomous thinking, and how can we observe them? As Robert Young's Habermasian work on indoctrination and conversational genres seemed a promising conceptual framework for understanding classroom situations in this respect, we took it as a starting point for exploring answers to these questions. Our exploration, both through fieldwork and theoretical reflection, led us to some findings, among which are (1) the existence of new genres which refine the conceptual categories originally formulated by Young; (2) that analysis of function is not enough, requiring also a contents dimension with which one can study what critical autonomous thinking is promoted about, in particular classroom situations; and (3) that classroom situations can be more contradictory and fragmented than presupposed by the very idea of genre.  相似文献   

Secondary School Students’ Errors in the Translation of Algebraic Statements     

Marta Molina  Susana Rodríguez-Domingo  María Consuelo Cañadas  Encarnación Castro 《International Journal of Science and Mathematics Education》2017,15(6):1137-1156

In this article, we present the results of a research study that explores secondary students’ capacity to perform translations of algebraic statements between the verbal and symbolic representation systems through the lens of errors. We classify and compare the errors made by 2 groups of students: 1 at the beginning of their studies in school algebra and another 1 completing their studies on algebra in compulsory education. This comparison allows us to detect errors which require specific attention in instruction due to its persistence and to identify errors that disappear as students advance in their study of algebra. The results and conclusions have a pedagogic value to inform instruction and also lead to backed conjectures and research questions to push forward research on student’s translation capacity and students’ knowledge of algebraic symbolism.  相似文献   

Does generating examples aid proof production?     

Paola Iannone  Matthew Inglis  Juan Pablo Mejía-Ramos  Adrian Simpson  Keith Weber 《Educational Studies in Mathematics》2011,77(1):1-14

Many mathematics education researchers have suggested that asking learners to generate examples of mathematical concepts is an effective way of learning about novel concepts. To date, however, this suggestion has limited empirical support. We asked undergraduate students to study a novel concept by either tackling example generation tasks or reading worked solutions to these tasks. Contrary to suggestions in the literature, we found no advantage for the example generation group on subsequent proof production tasks. From a second study, we found that undergraduate students overwhelmingly adopt a trial and error approach to example generation and suggest that different example generation strategies may result in different learning gains. We conclude by arguing that the teaching strategy of example generation is not yet understood well enough to be a viable pedagogical recommendation.  相似文献   

Researchers' attitudes and perceptions towards data sharing and data reuse in the field of food science and technology     

Remedios Melero  Carolina Navarro‐Molina 《Learned Publishing》2020,33(2):163-179

This work analyses the perception and practice of sharing, reusing, and facilitating access to research data in the field of food science and technology. The study involved the coordination of a focus group discussion and an online survey, to understand and evince the behaviour of researchers regarding data management in that field. Both the discussion group and the survey were performed with researchers from several institutes of the Spanish National Research Council. The lack of a data sharing culture, the fear of being scooped, and confusion between the concepts of the working plan and the data management plan were some of the issues that emerged in the focus group. Respondents' previous experience with sharing their research data has been mainly in the form of appendices to peer‐reviewed publications. From the survey (101 responses), the most important motivations for publishing research data were found to be facilitating the reproducibility of the research, increasing the likelihood of citations of the article, and compliance with funding body mandates. Legal constraints, intellectual property, data ownership, data rights, potential commercial exploitation, and misuse of data were the main barriers to publishing data as open data. Citation in publications, certification, compliance with standards, and the reputation of the data providers were the most relevant factors affecting the use of other researchers' data. Being recent or recently updated, well documented, with quality metadata and ease of access were the most valued attributes of open research data.  相似文献   

The open access movement and Cuban health research work: an author survey     

Nancy Sánchez‐Tarragó  J. Carlos Fernández‐Molina 《Health information and libraries journal》2010,27(1):66-74

  相似文献   

The elixir (or burden) of youth? Exploring differences in innovation between start-ups and established firms     

Paola Criscuolo  Nicos Nicolaou 《Research Policy》2012,41(2):319-333

Despite the widely acknowledged role of start-ups in economic development, little is known about their innovative activities compared with those of established firms. Drawing on a sample of 12,209 UK firms, we differentiate between services and manufacturing firms and, using a matching estimator approach, demonstrate that start-ups differ significantly from established firms in their innovation activities. We find that in services, being a start-up increases the likelihood of product innovations. However, in manufacturing, we find no significant differences in the likelihood of product innovation between start-ups and established firms. When examining the returns to innovation, we find that start-ups have a significant advantage both in services and in manufacturing. We explore the implications of these results for theory and policy.  相似文献   

Reading minds: the relation between children's mental state knowledge and their metaknowledge about reading   总被引：1，自引：0，他引：1  

Lecce S  Zocchi S  Pagnin A  Palladino P  Taumoepeau M 《Child development》2010,81(6):1876-1893

The relation between children's mental state knowledge and metaknowledge about reading was examined in 2 studies. In Study 1, 196 children (mean age = 9 years) were tested for verbal ability (VA), metaknowledge about reading, and mental state words in a story task. In Study 2, the results of Study 1 were extended by using a cross-lagged design and by investigating older children (N = 71, mean ages = 10 years at Time 1 and 11 years at Time 2) for mental state knowledge, metaknowledge about reading, and VA. Results showed a significant relation between early cognitive (but not emotion) mental state knowledge and later metaknowledge about reading, controlling for VA. Results suggest close links between different aspects of children's knowledge about the mind.  相似文献   

Transitioning to CBT     

Carla A. Molina 《Performance Improvement》1995,34(9):26-33

  相似文献   

Principal component analysis of colour measurements of patinas and coating systems for outdoor bronze monuments   总被引：1，自引：0，他引：1  

Giorgio Luciano  Riccardo Leardi  Paola Letardi   《Journal of Cultural Heritage》2009,10(3):331-337

Principal Component Analysis (PCA) was applied on colour measurements performed on outdoor bronze patinas and protective coating systems on bronze coupons in order to monitor natural weathering and cleaning effects. PCA chemometric technique is shown to be a powerful tool to analyse the large measurement data set which is needed to characterise these kinds of system. The results are compared with previous work where the CIELAB L*a*b space was used, in order to spot the advantages and disadvantages of both techniques and how they can complete each other in order to set up a workflow when dealing with large datasets of colour measurements. As previously stated, quicker colour variations in the early stage of natural weathering of bronze coupons are characterised, which is mainly due to lightness reduction. PCA analysis helps to visualise the different behaviour upon cleaning procedure of different monument patinas and colour difference reduction due to cleaning. It gives the advantage in a first screening phase to possibly highlight the presence of outliers, check the level of noise in the spectra, and select the variables which carry more information. Its integration in a workflow for colour measurement can help in speeding up the process of later analysing data with the well-established CIELAB system.  相似文献