Effect of <Emphasis Type="Italic">Curcuma longa</Emphasis> freeze dried rhizome powder with milk in STZ induced diabetic rats     

P. K. Rai  D. Jaiswal  S. Mehta  D. K. Rai  B. Sharma  Geeta Watal 《Indian journal of clinical biochemistry : IJCB》2010,25(2):175-181

This study deals with the effects of freeze dried rhizome powder of Curcuma longa (C. longa) dissolved in milk on normal as well as diabetic models. Diabetes of type II and type I was within 3 days of a single administration of doses of 45 and 65 mg kg⁻¹ of streptozotocin respectively. Various parameters such as blood glucose levels, triglycerides, total cholesterol, high density lipoprotein, very low density lipoprotein, low density lipoprotein, serum glutamic oxaloacetic transaminase, serum glutamic pyruvate transaminase, alkaline phosphatase, creatinine, hemoglobin, urine protein and urine sugar in addition to body weight were taken in to consideration and were analyzed after administration of variable doses of rhizome powder. The dose of 200 mg kg⁻¹ was identified as the most effective dose as it increased HDL, Hb and bw (P<0.05) with significant decrease in the levels of blood glucose, lipid profile and hepatoprotective enzymes (P<0.001).  相似文献   

Methods of Instruction and Learning Outcomes: A Theoretical Analysis of Two Approaches in an Introductory Information Technology Course*     

Jeannie L. Pridmore  Randy V. Bradley  Nikhil Mehta 《Decision Sciences Journal of Innovative Education》2010,8(2):289-311

In introductory information technology (IT) courses, communicating technical concepts so that they can be comprehended by all students, technical and nontechnical, has been a concern. Another challenge in such courses is to teach the real‐world applicability of technical concepts. In this conceptual article, we focus on a relatively unexplored issue in IT education—which instructional method is more effective in improving the learning outcomes of all students taking introductory IT courses. In doing so, we consider two instructional methods, lecture and multimedia case studies, and argue that either of these instructional methods, adopted singly, will be perceived by students as less effective in accomplishing learning outcomes than adopting a combination of the two instructional methods. Our arguments both augment existing knowledge about the differential influence of lecture and multimedia case studies on students’ learning outcomes and questions the wisdom of adopting either of these methods singly in introductory IT courses. We derive insights from the literature and anecdotal evidence, presented as four propositions, which illustrate the relationship between the two instructional methods and the specific learning outcomes students perceive they affect.  相似文献   

Hypocalcemia Presenting as Life Threatening Torsades de Pointes with Prolongation of QTc Interval     

Shibba Takkar Chhabra  Shivani Mehta  Sandeep Chhabra  Manikant Singla  Naved Aslam  Bishav Mohan  Gurpreet Singh Wander 《Indian journal of clinical biochemistry : IJCB》2018,33(2):235-238

Torsades de pointes with prolonged QTc interval is a form of ventricular tachycardia. Many predisposing factors have been identified and hypocalcemia is among the rare ones. Our case illustrates that though rare, hypocalcemia might manifest as torsades de pointes with prolongation of QTc interval. Early diagnosis and management of dyselectrolytemia can prevent these patients from catastrophic torsades de pointes.  相似文献   

Comparative education: The construction of a field     

Sonia Mehta 《International Review of Education/Internationale Zeitschrift für Erziehungswissenschaft/Revue internationale l'éducation》2013,59(1):137-139

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Determining the barriers contributing to ICT implementation by using technology-organization-environment framework in Ethiopian higher educational institutions     

Ergado  Amanuel Ayde  Desta  Amare  Mehta  Hemini 《Education and Information Technologies》2021,26(3):3115-3133

Education and Information Technologies - Information and communication technology (ICT) is an important element to improve teaching-learning practices. This paper is aimed to determine the barriers...  相似文献   

Effective aggregation of various summarization techniques     

Parth Mehta  Prasenjit Majumder 《Information processing & management》2018,54(2):145-158

A large number of extractive summarization techniques have been developed in the past decade, but very few enquiries have been made as to how these differ from each other or what are the factors that actually affect these systems. Such meaningful comparison if available can be used to create a robust ensemble of these approaches, which has the possibility to consistently outperform each individual summarization system. In this work we examine the roles of three principle components of an extractive summarization technique: sentence ranking algorithm, sentence similarity metric and text representation scheme. We show that using a combination of several different sentence similarity measures, rather than only one, significantly improves performance of the resultant meta-system. Even simple ensemble techniques, when used in an informed manner, prove to be very effective in improving the overall performance and consistency of summarization systems. A statistically significant improvement of about 5% to 10% in ROUGE-1 recall was achieved by aggregating various sentence similarity measures. As opposed to this aggregation of several ranking algorithms did not show a significant improvement in ROUGE score, but even in this case the resultant meta-systems were more robust than candidate systems. The results suggest that new extractive summarization techniques should particularly focus on defining a better sentence similarity metric and use multiple sentence similarity scores and ranking algorithms in favour of a particular combination.  相似文献   

Multilevel Factorial Invariance in n-Level Structural Equation Modeling (nSEM)     

Ehri Ryu  Paras Mehta 《Structural equation modeling》2017,24(6):936-959

We present a multigroup multilevel confirmatory factor analysis (CFA) model and a procedure for testing multilevel factorial invariance in n-level structural equation modeling (nSEM). Multigroup multilevel CFA introduces a complexity when the group membership at the lower level intersects the clustered structure, because the observations in different groups but in the same cluster are not independent of one another. nSEM provides a framework in which the multigroup multilevel data structure is represented with the dependency between groups at the lower level properly taken into account. The procedure for testing multilevel factorial invariance is illustrated with an empirical example using an R package xxm2.  相似文献   

Filaria associated clinical manifestations in children in an endemic area and morbidity control by immunomonitoring and optimal DEC therapy: Sevagram experience     

B. C. Harinath  M. V. R. Reddy  B. Bhunia  Y. P. Bhandari  V. K. Mehta  P. Chaturvedi  N. C. Prajapati  R. K. C. Gupta 《Indian journal of clinical biochemistry : IJCB》2000,15(1):118-126

Lymphatic filariasis is a major public health problem in India with 412 million people living in bancroftian endemic areas and is a major cause of clinical morbidity. Twenty million people are reported to suffer from chronic disease manifestations such as lymphoedema, hydrocele or elephantiasis. At least twice the number have been shown to suffer from acute and occult filarial infections in an endemic area without diagnosis. Due to non-availability of suitable diagnostic test for confirming filaria aetiology other than parasitological examination, no significant study on filariasis in children has been reported earlier. Studies in our laboratory for more than a decade showed usefulness of microfilarial excretory-secretory antigen in confirming filarial aetiology in acute and occult infections in adults as well as in children. This study reports acute and atypical manifestations such as lymphadenopathy, asthmatic bronchitis, pulmonary eosinophilia, mono-arthritis, recurrent URI, pneumonia, nutritional anemia, pain in abdomen etc. in children living in filaria endemic area having no microfilaraemia but showing filaria aetiology by immunomonitoring for the presence of antibody or antigen and responding to optimal DEC therapy.  相似文献   

Hyperhomocysteinemia and cardiovascular disease: The nutritional perspectives     

Rajesh Pandey  Seema Gupta  Harbans Lal  H. C. Mehta  S. K. Aggarwal 《Indian journal of clinical biochemistry : IJCB》2000,15(1):20-30

Several members of the vitamin B-complex family are known to participate in the normal metabolism of homocysteine (Hcy). Leaving aside the genetic determinants of hyperhomocysteinemia (HHC), the deficiencies of these vitamins can also result in HHC. The situation of sustained and long standing HHC is likely to be prevalent in population groups with low/average socio-economic status, geriatric population and alcohol abusers. If not corrected by supplementation, these population groups certainly are more vulnerable to develop atherosclerosis (AS) and subsequently, cardiovascular disease (CVD). Hyperhomocysteinemia per se and/or HHC-induced oxidative stress result(s) in chronic chemical endothelial injury/dysfunction, smooth muscle proliferation, prothrombotic state and oxidation of low density lipoproteins (LDL) leading to diverse cardiovascular complications. In the first decade of the new millennium, major research efforts would be directed towards understanding the basic mechanism of HHC-induced oxidative stress and the pathophysiology of HHC-induced CVD, culminating in the evolution of hitherto unknown therapeutic strategies such as nutriceuticals and oxidant-antidotes.  相似文献   

Microfluidic device capable of medium recirculation for non-adherent cell culture     

Angela R. Dixon  Shrinidhi Rajan  Chuan-Hsien Kuo  Tom Bersano  Rachel Wold  Nobuyuki Futai  Shuichi Takayama  Geeta Mehta 《Biomicrofluidics》2014,8(1)

We present a microfluidic device designed for maintenance and culture of non-adherent mammalian cells, which enables both recirculation and refreshing of medium, as well as easy harvesting of cells from the device. We demonstrate fabrication of a novel microfluidic device utilizing Braille perfusion for peristaltic fluid flow to enable switching between recirculation and refresh flow modes. Utilizing fluid flow simulations and the human promyelocytic leukemia cell line, HL-60, non-adherent cells, we demonstrate the utility of this RECIR-REFRESH device. With computer simulations, we profiled fluid flow and concentration gradients of autocrine factors and found that the geometry of the cell culture well plays a key role in cell entrapping and retaining autocrine and soluble factors. We subjected HL-60 cells, in the device, to a treatment regimen of 1.25% dimethylsulfoxide, every other day, to provoke differentiation and measured subsequent expression of CD11b on day 2 and day 4 and tumor necrosis factor-alpha (TNF-α) on day 4. Our findings display perfusion sensitive CD11b expression, but not TNF-α build-up, by day 4 of culture, with a 1:1 ratio of recirculation to refresh flow yielding the greatest increase in CD11b levels. RECIR-REFRESH facilitates programmable levels of cell differentiation in a HL-60 non-adherent cell population and can be expanded to other types of non-adherent cells such as hematopoietic stem cells.  相似文献