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21.
The estimation of electrolytes like sodium (Na+), potassium (K+) and chloride (Cl) using direct and indirect ion-selective electrodes (ISE) is a routine laboratory practice. Interferents like proteins, triglycerides, drugs etc. are known to affect the results. The present study was designed to look into the effect of increasing glucose concentrations on estimation of Na+, K+ and Cl by direct and indirect ISE. Pooled sera was mixed with glucose stock solution (20 g/dL) prepared in normal saline to obtain glucose concentrations ranging from ~100 to ~5000 mg/dL. Na+, K+ and Cl levels were estimated by direct and indirect ISE analyzers and results were statistically analysed using ANOVA and Pearson’s correlation. Similar experiment was also performed in 24 h urine sample from healthy subjects. Significant difference was observed between Na+ and Cl measurements by direct and indirect ISE, with indirect ISE values being consistently higher than direct ISE. Besides this, significant difference was observed amongst Na+ and Cl values from baseline values obtained by indirect ISE at glucose concentrations ≥2486 mg/dL. However, no such difference was observed with direct ISE. Na+ and Cl estimation by indirect ISE showed significant negative correlation with glucose concentration, more so, above ~2000 mg/dL. K+, however, showed no significant difference with varying glucose. Similar results were observed in 24 h urine samples with a significant difference observed amongst Na+ and Cl values at ≥2104 mg/dL glucose. Thus we conclude that high glucose concentrations interfere significantly in estimation of Na+ and Cl by indirect ISE in serum as well as urine.

Electronic supplementary material

The online version of this article (doi:10.1007/s12291-015-0522-0) contains supplementary material, which is available to authorized users.  相似文献   
22.
In 1843 Hamilton discovered the quaternions and in the same year Graves found an algebra with 8 basis elements. So, mathematicians knew the division algebra structures (over ℝ) on ℝ, ℝ2, ℝ4 and ℝ8 in the first half of the 19th century itself. It took more than 100 years to prove that these are all the division algebras over ℝ. This follows from a theorem of Adams (which we will discuss in Part 2). In this part we also discuss ‘vector products’ on ℝ3 and ℝ7 and Hurwitz’s theorem on ‘sums of squares formulae’  相似文献   
23.
In the first part of this article we discussed the nonexistence of division algebra structures and vector products on ℝn. We now show how results fromtopology can be used to prove the results in the first article.While the discussion in the first part of the article required only elementary mathematics, this (second) part requires notions from basictopology, with which, we hope, many students at the M Sc level are familiar.  相似文献   
24.
In December 2019, Wuhan city in the Hubei province of China reported for the first time a cluster of patients infected with a novel coronavirus, since then there has been an outburst of this disease across the globe affecting millions of human inhabitants. Severe acute respiratory syndrome coronavirus type-2 (SARS-CoV-2), is a member of beta coronavirus family which upon exposure caused a highly infectious disease called novel coronavirus disease-2019 (COVID-19). COVID-19, a probably bat originated disease was declared by World Health Organization (WHO) as a global pandemic in March 2020. Since then, despite rigorous global containment and quarantine efforts, the disease has affected nearly 56,261,952 laboratory confirmed human population and caused deaths of over 1,349,506 lives worldwide. Virus passes in majority through respiratory droplets and then enters lung epithelial cells by binding to angiotensin converting enzyme 2 (ACE2) receptor and there it undergoes replication and targeting host cells causing severe pathogenesis. Majority of human population exposed to SARS-CoV-2 having fully functional immune system undergo asymptomatic infection while 5–10% are symptomatic and only 1–2% are critically affected and requires ventilation support. Older people or people with co-morbidities are severely affected by COVID-19. These categories of patients also display cytokine storm due to dysfunctional immune response which brutally destroys the affected organs and may lead to death in some. Real time PCR is still considered as standard method of diagnosis along with other serology, radiological and biochemical investigations. Till date, no specific validated medication is available for the treatment of COVID-19 patients. Thus, this review provides detailed knowledge about the different landscapes of disease incidence, etiopathogenesis, involvement of various organs, diagnostic criteria’s and treatment guidelines followed for management of COVID-19 infection since its inception. In conclusion, extensive research to recognize novel pathways and their cross talk to combat this virus in precarious settings is our future positive hope.  相似文献   
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Total plasma homocysteine was analysed in 64 cases of retinal vein occlusion (RVO) of which 24 cases of central retinal vein occlusion (CRVO) and 40 cases of branch retinal vein occlusion (BRVO) and compared with 45 age and sex matched control. Homocysteine was significantly increased in RVO cases in respect to control (P < 0.001). Analysis also revealed that prevalence of rise of plasma homocysteine was more in cases of CRVO (OR = 13) than that of BRVO (OR = 5.03).  相似文献   
27.
Percent contrast thresholds for the detection of 1 or 8 cycle/degree sinusoidalgratings flickering in counter-phase at 1 or 10Hz were evaluated in 356 8–19 year old twinsand their school-age siblings. 107 of the twinshad a school history of reading disability.Subjects adjusted contrast levels to thresholdfrom above and below in a total of 32 trialsover about 12 minutes. Internal reliability foreach of the 4 stimulus conditions was 0.8, andeach stimulus condition was similarlycorrelated at 0.2–0.3 with several measuresof reading and phonological processing,suggesting modest relations with readingdeficits for both parvocellular (sustained) andmagnocellular (transient) visual processes. Thevariance in the word-reading measure that wasrelated to visual contrast thresholds waslargely shared with full-scale IQ, although IQand reading each also accounted for small(1%) but statistically significant amounts ofadditional independent variance in contrastthresholds. Word reading and nonword readingalso accounted for largely overlapping variancein contrast thresholds, but with a small (1%)amount of independent variance for nonwordreading. A behavioral-genetic analysis of themonozygotic and dizygotic twin correlationsindicated no significant genetic influence onindividual differences in contrast-thresholdlevels.  相似文献   
28.
Over the past two decades, both developed and developing countries have been investing a significant portion of their resources in the creation of an information infrastructure. However, speculation abounds regarding the efficacy of information infrastructure investments, especially when the opportunity cost for investing in information technology (IT) is measurably high among developing nations. This longitudinal study introduces and explores infrastructure development and service-sector growth as key metrics for IT investment success. It also traces the notional evidence of IT infrastructure development as mediating the causal relationship between information infrastructure investments and service-sector growth. Using data from low-income, middle-income, and high-income countries, the mediating and lagged impact of information infrastructure on service-sector growth reveals that information infrastructure development does play a significant role as a mediator. It points out that information infrastructure investments can be a misleading causal antecedent if countries fail to develop their infrastructure. It also provides evidence of a recursive relationship between infrastructure development and service-sector growth. An exploratory time-series analysis across different country categories suggests that information infrastructures must be properly developed to reconcile the paradox. In addition, exploratory tests reveal a distinct divergence between infrastructure investments and infrastructure development among different country tiers.  相似文献   
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Mycorrhiza     
The symbiotic association between plant and fungi (mycorrhizal association) is an amazing phenomenon observed in nature. The mycorrhizal association is one of nature’s boons for sustainable agriculture. In today’s changing environment, indiscriminate use of pesticides and chemicals pose a great threat to the existence of mycorrhizal species. There is a need to spread awareness in order to save mycorrhizal fungi from extinction.  相似文献   
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