Integrated carbon fiber electrodes within hollow polymer microneedles for transdermal electrochemical sensing     

Miller PR  Gittard SD  Edwards TL  Lopez DM  Xiao X  Wheeler DR  Monteiro-Riviere NA  Brozik SM  Polsky R  Narayan RJ 《Biomicrofluidics》2011,5(1):13415

In this study, carbon fiber electrodes were incorporated within a hollow microneedle array, which was fabricated using a digital micromirror device-based stereolithography instrument. Cell proliferation on the acrylate-based polymer used in microneedle fabrication was examined with human dermal fibroblasts and neonatal human epidermal keratinocytes. Studies involving full-thickness cadaveric porcine skin and trypan blue dye demonstrated that the hollow microneedles remained intact after puncturing the outermost layer of cadaveric porcine skin. The carbon fibers underwent chemical modification in order to enable detection of hydrogen peroxide and ascorbic acid; electrochemical measurements were demonstrated using integrated electrode-hollow microneedle devices.  相似文献   

Note-taking within MetaTutor: interactions between an intelligent tutoring system and prior knowledge on note-taking and learning     

Gregory Trevors  Melissa Duffy  Roger Azevedo 《Educational technology research and development : ETR & D》2014,62(5):507-528

Hypermedia learning environments (HLE) unevenly present new challenges and opportunities to learning processes and outcomes depending on learner characteristics and instructional supports. In this experimental study, we examined how one such HLE—MetaTutor, an intelligent, multi-agent tutoring system designed to scaffold cognitive and metacognitive self-regulated learning (SRL) processes—interacts with learner’s prior domain knowledge to affect their note-taking activities and subsequent learning outcomes. Sixty (N = 60) college students studied with MetaTutor for 120 min and took notes on hypermedia content of the human circulatory system. Log-files and screen recordings of learner-system interactions were used to analyze notes for several quantitative and qualitative variables. Results show that most note-taking was a verbatim copy of instructional content, which negatively related to the post-test measure of learning. There was an interaction between prior knowledge and pedagogical agent scaffolding, such that low prior knowledge students took a greater quantity of notes compared to their high prior knowledge counterparts, but only in the absence of MetaTutor SRL scaffolding; when agent SRL scaffolding was present, the note-taking activities of low prior knowledge students were statistically equivalent to the number of notes taken by their high prior knowledge counterparts. Theoretical and instructional design implications are discussed.  相似文献   

An Ounce of Good Assessment is Worth a Pound of Analysis and a Ton of Cure     

Roger Kaufman 《Performance Improvement》2014,53(2):35-39

While it is conventional and comfortable to start professional performance improvement with analysis, doing so might make us wrong about 80% to 90% of the time. Analysis and cure, using Harless's (1975) immortal insight, are vital, but starting there is problematic. First do an assessment to justify where the organization is headed (and why go there) and then analysis and cure will be powerful.  相似文献   

Improving Workplace Performance     

Roger Chevalier 《Performance Improvement》2014,53(5):6-19

Every day, managers and supervisors are greeted at work by the difference between the present and desired levels of performance. Unfortunately, they immediately jump to implementing solutions without identifying the underlying causes. This article brings together the ideas, models, and tools found in several of my previous articles so they can be shared with managers and supervisors. The next steps can be found in my book, A Manager's Guide to Improving Workplace Performance.  相似文献   

Defining student diversity: categorizing and processes of marginalization in Swedish schools     

Eva Hjörne  Roger Säljö 《Emotional and Behavioural Difficulties》2014,19(3):251-265

The article presents an analysis of how diversity is defined and attended to in Swedish schools. The research reported has been carried out as a case study of categorizing practices that concern the uses of neuropsychiatric diagnoses, notably ADHD. The data were collected as part of a larger study. The interaction over a two-year period between the parents of a boy (William, aged 5.5 years) and representatives of the school (school psychologist, principal, teacher etc.) has been analysed. It is shown that parents and professionals provide different accounts of William’s difficulties. The parents, while not denying that their son causes problems in class, argue that the boy will mature and that the problems will disappear. The representatives of the school try to convince the parents that a neuropsychiatric examination of the boy will be beneficial to all parties. The long process of negotiation can be understood as a rhetorical drama, where the category ‘ADHD’ serves as the resolution of a complex institutional problem in the modern welfare state.  相似文献   

Not under my roof: parents,teens and the culture of sex / Not my kid: what parents believe about the sex lives of their teenagers     

Roger Ingham 《Sex education》2014,14(3):354-357

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Issues in dealing with sequential and temporal characteristics of self- and socially-regulated learning     

Roger Azevedo 《Metacognition and Learning》2014,9(2):217-228

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Effects of manipulating relative and absolute motion information during observational learning of an aiming task.     

S A Al-Abood  K Davids  S J Bennett  D Ashford  M Martinez Marin 《Journal of sports sciences》2001,19(7):507-520

In the visual perception perspective of observational learning, the manipulation of relative and absolute motion information in visual demonstrations optimally directs learners' search towards appropriate task solutions. We assessed the effect of emphasizing transformational information and removal of structural information using point-light kinematic displays in approximating the model's relative motion patterns. Participants viewed computer-simulated point-light demonstrations or normal video demonstrations before and intermittently throughout 100 acquisition trials with knowledge of results on an underarm modified-dart aiming task. On the next day, all participants performed 20 retention trials without demonstrations. The kinematics of spatial and temporal coordination and control variables were examined relative to the model's action, as well as performance scores. The results indicated that approximation of the model's spatial and temporal coordination and control patterns was achieved after observation of either type of demonstrations. No differences were found in movement outcomes. In a second experiment, the effects of manipulating absolute motion information by slow-motion demonstrations were examined relative to real-time demonstrations. Real-time demonstrations led to a closer approximation to the model's spatial and temporal coordination patterns and better outcome scores, contradicting predictions that slow-motion displays convey intact relative motion information. We speculate that the effect of visual demonstration speed on action perception and reproduction is a function of task constraints--that is, novelty or familiarity of relative motion of demonstrated activities.  相似文献   

Curriculum Lessons from Europe?     

Roger Merry 《British Journal of Special Education》1991,18(2):71-74

Next year Britain will enter the Single European Market. This may encourage greater alignment of special educational legislation here with the laws in other member countries. Roger Merry, senior lecturer in education, School of Education, Leicester University, asks what lesson can be learned from practice in Europe, especially in relation to the National Curriculum.  相似文献   

Book reviews     

Leonard Shatzkin  John Tebbel  Marc Aronson  Amy S. Doherty  Sally P. Bennett  Robert A. Colby  J. James Mancuso  Thomas L. Bonn 《Publishing Research Quarterly》1995,11(2):117-129

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