Benzodiazepine administration prevents the use of error-correction mechanisms during fear extinction     

Genevra Hart  Nathan M. Holmes  Justin A. Harris  R. Frederick Westbrook 《Learning & behavior》2014,42(4):383-397

Three experiments examined the effect of systemic administration of the benzodiazepine midazolam on extinction and re-extinction of conditioned fear. Experiment 1 demonstrated that midazolam administration prior to extinction of a conditioned stimulus (CS) impaired that extinction when rats were subsequently tested drug free; however, extinction was spared if rats were extinguished, reconditioned, and re-extinguished under midazolam. Experiment 2 provided a replication of this effect within-subjects; rats were conditioned to two CSs (A and B), extinguished to one (A-), reconditioned to both, and then extinguished/re-extinguished to both stimuli in compound (AB-), under either vehicle or midazolam. On the drug-free test, rats given midazolam froze more to the CS that had been extinguished (B) than the one that been re-extinguished (A). The final experiment examined whether extinction under midazolam was regulated by prediction error. Rats were trained with three CSs (A, B, C) and extinguished to two (A-, C-). These stimuli then underwent additional extinction under midazolam or vehicle, with one CS now presented in compound with the non-extinguished CS (AB-, C-). Rats were then tested for fear of A relative to C. Rats given vehicle showed a deepening of extinction to A relative to C, as is predicted from error-correction models; however, rats given midazolam failed to show any such discrepancy in responding. The results are interpreted to indicate that the drug reduced prediction error during extinction by reducing fear, and rats were able to re-extinguish fear via a retrieval mechanism that is independent of prediction error.  相似文献   

A mechanical synthesizer and analyzer     

Frederick W. Kranz 《Journal of The Franklin Institute》1927,204(2):245-262

  相似文献   

Reporting book prices     

Frederick C. Lynden 《Publishing Research Quarterly》1986,2(3):89-91

  相似文献   

Reporting book prices     

Frederick C. Lynden 《Publishing Research Quarterly》1987,3(1):82-84

  相似文献   

Integrating technical editing students into a multidisciplinary engineering project     

Rose Norman  Robert A. Frederick 《Technical Communication Quarterly》2013,22(2):163-189

A three‐year experiment in integrating technical editing students into a multidisciplinary engineering design project developed several ways of helping students apply classroom learning to practical problems. Each year, the engineering students formed Integrated Product Teams (IPTs) and the technical editing students provided editorial support, first as full members of IPTs, then as separate editorial support teams. Research from cooperative learning and teamwork indicates strategies and techniques for best integrating the technical editing students.  相似文献   

Touch your toes! Developing a direct measure of behavioral regulation in early childhood   总被引：6，自引：0，他引：6  

Claire E. Cameron Ponitz  Megan M. McClelland  Abigail M. Jewkes  Carol McDonald Connor  Carrie L. Farris  Frederick J. Morrison 《Early childhood research quarterly》2008

Behavioral aspects of self-regulation, including controlling and directing actions, paying attention, and remembering instructions, are critical for successful functioning in preschool and elementary school. In recent years, several direct assessments of these skills have appeared, but few studies provide complete psychometric data and many are not easy to administer. We developed a direct measure of children's behavioral regulation, the Head-to-Toes Task, and report performance of participants aged 36–78 months, including a group of Spanish-speaking children, from two different sites (N = 353; N = 92). We examined construct validity, examiner reliability, sources of variation, and associations between task scores and background characteristics. Results showed that the task was valid, reliable, and demonstrated variability in children's scores. A cross-classified hierarchical growth curve analysis indicated that girls, participants assessed in English, and higher-socioeconomic status (SES) children achieved slightly higher average scores than did boys, Spanish-speaking and lower-SES children, but effect sizes were small. Older participants achieved higher scores than did younger children, and there were no effects for site. Results suggest that the Head-to-Toes Task is an informative and easy-to-administer direct assessment of children's behavioral regulation. We discuss implications for its use in early childhood settings.  相似文献   

Untangling the effects of shared book reading: Multiple factors and their associations with preschool literacy outcomes   总被引：5，自引：0，他引：5  

Annemarie H. Hindman  Carol M. Connor  Abigail M. Jewkes  Frederick J. Morrison 《Early childhood research quarterly》2008

Evidence strongly suggests that shared book reading at home and in preschool is important for young children's development of the foundational skills required for the eventual mastery of decoding and comprehension. Yet the nuances of how learning from book reading might vary across these contexts and with children's skills are not well understood. One hundred and thirty children participating in a longitudinal investigation of literacy development were videotaped reading a storybook with a parent. Children were also videotaped in their 33 preschool classrooms during the instructional book-reading portion of the day. Readings were coded for adult and child contextualized and decontextualized language relating to both decoding and meaning-making skills, and relations between this talk and emergent literacy outcomes were analyzed. Results demonstrate that parents and teachers overwhelmingly focus their book-related talk on meaning-related rather than code-related information, and that the relations between outcomes and talk depend in part on children's initial levels of vocabulary skills. Implications for practice and research are discussed.  相似文献   

Disturbance Decoupled Observers Having Unrestricted Spectrum     

Frederick W. Fairman  Takao Hinamoto  Ronald Hirschorn 《Journal of The Franklin Institute》1982,313(3):123-133

The problem of observing the state of a linear finite dimensional system in the presence of unknown disturbance noise is considered. Necessary and sufficient conditions are developed for the existence of a minimal order observer capable of producing an asymptotic estimate of the state of the given system. The approach used leads to a computationally attractive procedure for obtaining an observer having specified eigenvalues.  相似文献   

Book reviews     

George Gerbner  Gabriel D. Ofiesh  Jerry M. Lewis  Frederick G. Knirk  F. Earle Barcus  Robert Steele 《Educational technology research and development : ETR & D》1966,14(3):407-416

  相似文献   

Support from Spouse as Mediator and Moderator of the Disruptive Influence of Economic Strain on Parenting     

Ronald L. Simons  Frederick O. Lorenz  Rand D. Conger  Chyi-In Wu 《Child development》1992,63(5):1282-1301

A model is presented regarding associations between economic strain, support from spouse, and quality of parenting. The model was tested using a sample of 451 2-parent families, each of which included a seventh grader (age 12-13). Parent and adolescent reports, as well as observational ratings, were used as indicators of constructs. Analysis using structural equation modeling procedures indicated that level of spouse support was positively related to supportive parenting, whereas economic strain operated to undermine parental involvement. As posited, economic strain produced its effect through a direct relation with parenting and indirectly through its association with spouse support. These findings held for mothers and fathers, regardless of the gender of the child. Spouse support moderated the impact of economic strain on supportive parenting for mothers but not fathers. Possible explanations for this gender difference are presented.  相似文献