Information studies, librarianship, and professional leadership     

W J Haas 《Bulletin of the Medical Library Association》1988,76(1):1-6

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Snow fun     

Carolyn Buhai Haas 《Early Childhood Education Journal》1985,13(2):43-45

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Adults'' Tolerance of Cries: An Experimental Investigation of Acoustic Features     

Rudolf Bisping  Hans Joachim Steingrueber  Martine Oltmann  Christine Wenk 《Child development》1990,61(4):1218-1229

Variations in the aversiveness of a newborn's distress cry were examined using experimental manipulation of 3 acoustic features of the cry (fundamental frequency, intonation, spectral complexity) and of the information given to subjects about the infant's health status. The subjects (N = 164 medical students) were allowed to control the sound pressure level (range: 50 dB [A]-105 dB[A]) of the different cry versions by repeatedly pressing a button (operant titration). For the nonmanipulated (original) cry version, the accepted sound pressure level decreased as fundamental frequency increased at above 610 Hz. This effect was modified by experimental manipulation of spectral complexity as well as intonation. A preference of intonated cries over monotonous cries was most pronounced between 534 and 686 Hz. Significant interactions of the information variable with the intonation and the complexity variables suggest that the listener's reaction to certain physical cry characteristics can be altered substantially by inducing different cognitive sets.  相似文献   

(2) Some problems of the collecting and processing of international information sources in the documentation and Information Centre of the City Library of Prague     

Rudolf Málek 《International Information and Library Review》2013,45(4):461-469

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The calling and condition of the humanistic disciplines     

Bernhard Fabian  Rudolf Vierhaus 《Minerva》1979,17(4):549-554

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Stichwort: Wandel pädagogischer Institutionen     

Rudolf Tippelt 《Zeitschrift für Erziehungswissenschaft》2000,3(1):7-20

Ohne Zusammenfassung  相似文献   

Die ganztagsschule in der ČSSR     

Rudolf Opata 《International Review of Education/Internationale Zeitschrift für Erziehungswissenschaft/Revue internationale l'éducation》1962,8(2):214-220

Ohne Zusammenfassung  相似文献   

Management of Innovations from a Cultural-Individual Perspective     

Rudolf van den Berg  Roland Vandenberghe  Peter Sleegers 《School Effectiveness & School Improvement》2013,24(3):321-351

The history of education and schooling is characterised by not only the attainment of results but also ongoing critique of the existing situation in education and schooling. Developers and researchers are, as a result, constantly seeking new strategies and methods for the improved implementation of innovations in actual educational practice. The central question is which factors and which conditions facilitate the effects of innovations. In an attempt to answer this question, many educators will not so much be concerned with objective structural factors such as available funds, classmates, et cetera. They will be concerned, rather, with the questions of which socially constructed realities and which particular forms of involvement on the part of teachers, school administrators, and counsellors facilitate successful innovation. In our search for an answer to these questions, moreover, we will be guided by a cultural-individual perspective on innovation. Traditional innovative strategies – and, in particular, large scale strategies – seem not always suitable to deal with today's educational problems. Alternative scenario's for the management of innovations are considered.  相似文献   

Review of the proceedings of the 2001, 2003 and 2005 French summer schools in Didactics of Mathematics     

Rudolf Sträßer 《Educational Studies in Mathematics》2008,69(3):277-281

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A single nucleotide mutation in the dual-oxidase 2 (DUOX2) gene causes some of the panda's unique metabolic phenotypes     

Agata M Rudolf  Qi Wu  Li Li  Jun Wang  Yi Huang  Jacques Togo  Christopher Liechti  Min Li  Chaoqun Niu  Yonggang Nie  Fuwen Wei  John R Speakman 《国家科学评论(英文版)》2022,9(2)

The giant panda (Ailuropoda melanoleuca) is an iconic bear native to China, famous for eating almost exclusively bamboo. This unusual dietary behavior for a carnivore is enabled by several key adaptations including low physical activity, reduced organ sizes and hypothyroidism leading to lowered energy expenditure. These adaptive phenotypes have been hypothesized to arise from a panda-unique single-nucleotide mutation in the dual-oxidase 2 (DUOX2) gene, involved in thyroid hormone synthesis. To test this hypothesis, we created genome-edited mice carrying the same point mutation as the panda and investigated its effect on metabolic phenotype. Homozygous mice were 27% smaller than heterozygous and wild-type ones, had 13% lower body mass-adjusted food intake, 55% decreased physical activity, lower mass of kidneys (11%) and brain (5%), lower serum thyroxine (T4: 36%), decreased absolute (12%) and mass-adjusted (5%) daily energy expenditure, and altered gut microbiota. Supplementation with T4 reversed the effects of the mutation. This work uses a state-of-the-art genome editing approach to demonstrate the link between a single-nucleotide mutation in a key endocrine-related gene and profound adaptive changes in the metabolic phenotype, with great importance in ecology and evolution.  相似文献