排序方式： 共有59条查询结果，搜索用时 31 毫秒
21.
Leonelli S 《Endeavour》2007,31(1):34-38
The small flowering plant Arabidopsis thaliana is the best-studied model organism in plant biology. More resources are allocated to research on this little weed than to the study of well-known favourites such as worms, fruit flies and mice. Yet, up to the early 1980s plant biologists had every good reason to ignore Arabidopsis: neither did it seem to possess the characteristics of a good model organism, nor did it have any agricultural promise. The sudden prestige acquired by Arabidopsis research thus constitutes a remarkable historical puzzle. What made the mouse cress into the most successful model organism to date? 相似文献
22.
Caroline Sabina Wekullo 《Journal of Higher Education Policy & Management》2017,39(4):453-468
Outsourcing or privatising services in higher education is a common practice, but what do we really know about it? Is outsourcing effective? It is imperative that these questions be addressed since outsourcing is becoming a norm in higher education institutions. Scholars, institutional administrators and policymakers need to understand the outsourcing phenomenon and whether it is beneficial. However, there has been little research documenting the cost-effectiveness or difference in the quality of service associated with outsourcing. This study reviews 30 empirical articles to find out whether outsourcing is effective, examines the knowns and unknowns about outsourcing, and the theories often used in outsourcing in higher education. The findings show that the effect of outsourcing varies across the institution, and ranges from the positive, negative, mixed, to no effect. Over time, outsourcing may become expensive for both institutions and students because of the profit factors intrinsic within private enterprises. 相似文献
23.
Zhu Huiyuan Yan Shaochun Wu Jingshuo Zhang Zhong Li Xiaolin Liu Zheng Ma Xing Zhou Lina Zhang Lin Feng Mingming Geng Yiwei Zhang Aixin Janciauskiene Sabina Xu Aiguo 《Journal of Zhejiang University. Science. B》2021,22(6):512-520
Background: Previous studies have shown that macrophage migration inhibitory factor(MIF) is involved in the pathogenesis of asthma. This study aimed to investigate whether serum MIF reflects a therapeutic response in allergic asthma.Methods: We enrolled 30 asthmatic patients with mild-to-moderate exacerbations and 20 healthy controls, analyzing the parameter levels of serum MIF, serum total immunoglobulin E(tIgE), peripheral blood eosinophil percentage(EOS%), and fractional exhaled nitric oxide(FeNO). Lung function indices were used to identify disease severity and therapeutic response.Results: Our study showed that all measured parameters in patients were at higher levels than those of controls. After one week of treatment, most parameter levels decreased significantly except for serum tIgE. Furthermore, we found that serum MIF positively correlated with EOS% as well as FeNO, but negatively correlated with lung function indices. Receiver operator characteristic(ROC) curve analysis indicated that among the parameters, serum MIF exhibited a higher capacity to evaluate therapeutic response. The area under the curve(AUC) of MIF was 0.931, with a sensitivity of 0.967 and a specificity of 0.800.Conclusions: Our results suggested that serum MIF may serve as a potential biomarker for evaluating therapeutic response in allergic asthma with mild-to-moderate exacerbations. 相似文献
24.
Svetlana Chachashvili-Bolotin Marina Milner-Bolotin Sabina Lissitsa 《International Journal of Science Education》2016,38(3):366-390
Based on the Social Cognitive Career Theory (SCCT), the study aims to investigate factors that predict students’ interest in pursuing science, technology, engineering, and mathematics (STEM) fields in tertiary education both in general and in relation to their gender and socio-economic background. The results of the analysis of survey responses of 2458 secondary public school students in the fifth-largest Israeli city indicate that STEM learning experience positively associates with students’ interest in pursuing STEM fields in tertiary education as opposed to non-STEM fields. Moreover, studying advanced science courses at the secondary school level decreases (but does not eliminate) the gender gap and eliminates the effect of family background on students’ interest in pursuing STEM fields in the future. Findings regarding outcome expectations and self-efficacy beliefs only partially support the SCCT model. Outcome expectations and self-efficacy beliefs positively correlate with students’ entering tertiary education but did not differentiate between their interests in the fields of study. 相似文献
25.
Competence assessment can support evidence-based teaching and learning. Depending on its specific purpose, competence assessment can be applied at the individual, the classroom or school level as well as on a national level. Large-scale-assessments are typical examples for system monitoring. Competence assessment on the individual level can provide important information with respect to individual qualification and learning outcomes. Typically, competence assessment uses psychometric models from Item-Response-Theory (IRT). However, until present, competence assessment still struggles to tap its full potential regarding feedback and individual support. Teachers often have difficulties to interpret results from competence assessments that are based on IRT. Thus, it is crucial to support teachers in using these results to improve classroom teaching. One of the main challenges of educational measurement is to align everyday classroom teaching with formative and summative assessments and to establish competence models as a common ground. Process-orientated, formative assessment can inform criterion-based feedback and, consequently, promote teaching on the basis of educational standards that were defined on the system level. However, more work needs to be done with respect to research on assessments as well as their communication and implementation into teaching practice. 相似文献
26.
ABSTRACT Timor-Leste is an emerging young nation that has many ambitious plans for its people. After a long period of conflict major projects focus on rebuilding the country, including education. Libraries are regarded as an essential part of the young nation's intellectual capital development. The authors will focus on the opportunities and challenges that face the country's national university, Universidade Nacionál Timór Lorosa’e Timor-Leste (UNTL), in the redevelopment of its library and services. 相似文献
27.
The aim of the study was to examine factors that predict maternal stress, reported by mothers whose infants were diagnosed as having developmental disabilities at the beginning of participating in an early intervention programme ‘Me and My Mommy’ and after one year. A second goal was to identify and to portray a subgroup of resilient mothers. The sample consisted of 70 mothers from intact families, whose infants were diagnosed mostly with Down’s syndrome. All mothers were receiving early intervention services. The mothers were presented questionnaires—Sense of coherence (SOC); Family adaptability and cohesion evaluation (FACES III); Coping scale of parenting stress index (PSI‐SF), at the beginning and at the end of the year. They were also interviewed at the end of the intervention regarding their satisfaction with the programme. The results showed that at the beginning of the year, the mothers’ sense of coherence had predicted the stress experience. After a year of participation in the intervention, in addition to the contributions of the initial stress and the mothers’ satisfaction with the intervention programme, the following variables: the mothers’ sense of coherence, coping style and family cohesion, assessed at the beginning of the intervention, were considered. A group of resilient mothers was identified and they revealed following intervention a higher sense of coherence, lower stress, an increased family cohesion and decreased family adaptation measures. The results have implications for the planning of effective intervention programmes. 相似文献
28.
Helem Sabina Sánchez Damiano Rotondo Teresa Escobet Vicenç Puig Jordi Saludes Joseba Quevedo 《Journal of The Franklin Institute》2019,356(5):2798-2824
This paper proposes a frequency-based approach for the detection of replay attacks affecting cyber-physical systems (CPS). In particular, the method employs a sinusoidal signal with a time-varying frequency (authentication signal) into the closed-loop system and checks whether the time profile of the frequency components in the output signal are compatible with the authentication signal or not. In order to carry out this target, the couplings between inputs and outputs are eliminated using a dynamic decoupling technique based on vector fitting. In this way, a signature introduced on a specific input channel will affect only the output that is selected to be associated with that input, which is a property that can be exploited to determine which channels are being affected. A bank of band-pass filters is used to generate signals whose energies can be compared to reconstruct an estimation of the time-varying frequency profile. By matching the known frequency profile with its estimation, the detector can provide the information about whether a replay attack is being carried out or not. The design of the signal generator and the detector are thoroughly discussed, and an example based on a quadruple-tank process is used to show the application and effectiveness of the proposed method. 相似文献
29.
Helem Sabina Sánchez Antonio Visioli Ramon Vilanova 《Journal of The Franklin Institute》2017,354(10):3945-3970
In this paper, we propose tuning rules for one degree-of-freedom proportional-integral-derivative controllers, by considering important aspects such as the trade-off in the performance in the servo and regulation operation modes and the control system robustness by constraining the maximum sensitivity peak. The different conflicting objectives are dealt with by using a multi-objective optimization algorithm to generate the trade-off optimal solutions. In this context, a simple tuning rule is determined by using the Nash solutions as a multi-criteria decision making technique. The Nash criteria is shown to provide convenient trade-off solutions for the controller tuning problem. Illustrative simulation examples show the effectiveness of the method. 相似文献
30.