Biocompatible chitosan/polyethylene glycol/multi-walled carbon nanotube composite scaffolds for neural tissue engineering     

Shengbo SANG  Rong CHENG  Yanyan CAO  Yayun YAN  Zhizhong SHEN  Yajing ZHAO  Yanqing HAN 《Journal of Zhejiang University. Science. B》2022,23(1):58-73

Carbon nanotube(CNT)composite materials are very attractive for use in neural tissue engineering and biosensor coatings.CNT scaffolds are excellent mimics of extracellular matrix due to their hydrophilicity,viscosity,and biocompatibility.CNTs can also impart conductivity to other insulating materials improve mechanical stability guide neuronal cell behavior and trigger axon regeneration.The performance of chitosan(CS)/polyethylene glycol(PEG)composite scaffolds could be optimized by introducing multi-walled CNTs(MWCNTs).CS/PEG/CNT composite scaffolds with CNT content of 1%,3%,and 5%(1%=0.01 g/mL)were prepared by freeze-drying.Their physical and chemical properties and biocompatibility were evaluated.Scanning electron microscopy(SEM)showed that the composite scaffolds had a highly connected porous structure.Transmission electron microscope(TEM)and Raman spectroscopy proved that the CNTs were well dispersed in the CS/PEG matrix and combined with the CS/PEG nanofiber bundles.MWCNTs enhanced the elastic modulus of the scaffold.The porosity of the scaffolds ranged from 83%to 96%.They reached a stable water swelling state within 24 h,and swelling decreased with increasing MWCNT concentration.The electrical conductivity and cell adhesion rate of the scaffolds increased with increasing MWCNT content.Immunofluorescence showed that rat pheochromocytoma(PC12)cells grown in the scaffolds had characteristics similar to nerve cells.We measured changes in the expression of nerve cell markers by quantitative real-time polymerase chain reaction(qRT-PCR),and found that PC12 cells cultured in the scaffolds expressed growth-associated protein 43(GAP43),nerve growth factor receptor(NGFR),and class IIIβ-tubulin(TUBB3)proteins.Preliminary research showed that the prepared CS/PEG/CNT scaffold has good biocompatibility and can be further applied to neural tissue engineering research.  相似文献   

Teachers’ stages of concern for media literacy education and the integration of MLE in Chinese primary schools     

Hui Zhang  Chang Zhu  Guoyuan Sang 《Asia Pacific Education Review》2014,15(3):459-471

Media literacy is an essential skill for living in the twenty-first century. School-based instruction is a critical part of media literacy education (MLE), while research on teachers’ concerns and integration of MLE is not sufficient. The objective of this study is to investigate teachers’ stages of concern (SoC), perceived need, school context, and teacher practices of the integration of MLE in primary schools. For this purpose, a survey was setup and 392 primary school teachers participated in this study. The results show that teachers’ concerns of integration of MLE were generally oriented at the level of self-concerns. In the meanwhile, the integration of MLE was significantly related to teachers’ concerns and perceived need for MLE. Based on the results of regression analysis, teachers’ integration of MLE was significantly influenced by their SoC for MLE, school professional development support, and leadership support.  相似文献   

体育旅游资源的美学探讨     

张忠凯  桑勇 《鸡西大学学报》2010,10(2):151-152

体育旅游活动有着丰富的内涵,其资源的美学特征是其形成吸引力的重要方面,因此本文采用文献资料、归纳、分析等研究方法,系统探讨了不同体育旅游资源的关学表现,并对其审美特征进行了分析。  相似文献   

The subak cultural landscape as environmental education: Knowledge,attitudes, and experiences of Balinese teachers,student teachers,and students     

Sang Putu Kaler Surata  Nyoman Utari Vipriyanti 《The Journal of environmental education》2018,49(1):59-70

Bali's subak cultural landscape, with its ancient and extensive paddy-fields and irrigation system, is a valuable resource for place-based education. However, this landscape is threatened by various problems. Here we analyze the relationships among Balinese teachers, student teachers, and students, and review their knowledge, attitudes, and experiences toward subaks. This study finds that most of the Balinese teachers, student teachers, and students had limited knowledge and experiences regarding subaks, although their overall attitudes were positive. We conclude by discussing the study's implications for relocating environmental education into the local context.  相似文献   

合资企业与其它企业的技术评价与比较   总被引：9，自引：0，他引：9  

陈国宏  郑绍濂  桑赓陶 《科研管理》1999,20(6):32-38

本将我国工业经济分为全部工业、合资企业、其它企业三个系统,设定评价项目为：企业技术基础、企业技术创新能力、企业技术创新投入。在确定了评价指标体系及其权重的基础上,通过对５３４个企业的调查、计算、评价及比较分析,从实证角度得出基本结论为：总体上我国合资企业技术基础高于其它企业,但在技术创新能力及投入上比其它企业无明显优势,合资企业对我国工业总体技术水平的直接影响主要是通过具有相对较高技术基础的合资  相似文献   

TCL语言在UG／Post中定制用户命令的运用研究     

桑华希  傅康 《科技广场》2010,(5):186-188

本文介绍了在UG/Post中通过使用TCL语言来定制用户命令的方法,并通过列举四个实用且常用的命令,阐述了TCL语言在UG/Post中的运用.在实际加工中,用TCL语言定制命令,用户基本上可以完成各种加工的要求.  相似文献   

企业信息系统实施中的创新扩散研究     

钟桑  邵波 《情报杂志》2010,29(2)

围绕企业信息系统实施全过程,从系统终端用户角度考虑信息系统实施时需采纳的创新,探索加强其在企业内扩散的策略,从而提高信息系统实施的效率.通过对实施各阶段的创新及其特点的阐述,并分析其在企业内扩散时遇到的问题,提出加强其在企业内扩散的策略,并以某集团ERP系统的实施为例,分析该集团针对实施中的创新已采取和应采取的措施,以更好地促进信息系统的实施.  相似文献   

How the Organizational Learning Process Mediates the Impact of Strategic Human Resource Management Practices on Performance in Korean Organizations     

Sei Hyoung Cho  Ji Hoon Song  Suk Chun Yun  Cheol Ki Lee 《Performance Improvement Quarterly》2013,25(4):23-42

The primary purpose of this research is to examine the structural relationships among several workplace‐related constructs, including strategic human resource management (HRM) practices, organizational learning processes, and performance improvement in the Korean business context. More specifically, the research examined the mediating effect of the organizational learning processes at three levels—individual, group, and organizational—to explain the relationship between strategic HRM practices and performance improvement. A total of 640 cases were used for data analysis, with general multivariate analyses and structural equation modeling. The results suggest that the learning processes at the three levels have a significant direct impact on organizational performance and that they also serve as a mediating interaction construct to maximize the effect of strategic HRM practices. The article provides conclusions, discusses the limitations of the research, and makes further recommendations.  相似文献   

A model of small group facilitator competencies     

Judith A. Kolb  Sungmi Jin  Ji Hoon Song 《Performance Improvement Quarterly》2008,21(2):119-133

This study used small group theory, quantitative and qualitative data collected from experienced practicing facilitators at three points of time, and a building block process of collection, analysis, further collection, and consolidation to develop a model of small group facilitator competencies. The proposed model has five components: communication, task, relationship or climate, organization, and professional ethics. “Listens actively” was the highest rated competency. Items under communication, in addition to listening, include “observes and attends to nonverbals in group members” and “uses questions skillfully.” Remaining competencies concern ground rules, creating a supportive climate, encouraging group involvement, and handling disruptive individuals, among others.  相似文献