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31.
Eshrat M. Halim A. K. Mukhopadhyay 《Indian journal of clinical biochemistry : IJCB》2006,21(2):181-188
This study was carried out to see the effect of the aqueous extract ofOcitum sanctum Linn (Tulsi) with Vitamin E on biochemical parameters and retinopathy in the streptozotocin-induced diabetic albino male
rats. Adult albino male rats weighing 150–200 gm were made diabetic by intraperitoneal injection of streptozotocin in the
dose 60 mg/kg in citrate buffer (pH 6.3). The diabetic animals were left for one month to develop retinopathy. Biochemical
parameters like plasma glucose, oral glucose tolerance and glycosylated hemoglobin HbA1c, were measured along with lipid profile, and enzymes like glutathione peroxidase (GPX), lipid peroxidase (LPO), superoxide
dismutase (SOD), catalase (CAT) and glutathione-S-transferase (GST) in normal, untreated diabetic rats and diabetic rats treated
withOcimum sanctum L extracts and vitamin E. Fluorescein angiography test was done for assessing retinopathy. Results on biochemical parameters
were analyzed statistically by using ANOVA followed by Dunnet's ‘t’-test. A p-value of <0.05 was considered as significant.
Evaluation of biochemical profile in treated groups showed statistically significant reduction in plasma levels of glucose,
HbA1c, lipid profile and LPO, and elevation of GPX, SOD, CAT and GST. Treatment of the diabetic animals withOcimum sanctum and Vitamin E, alone and in combination for 16 weeks showed reversal of most of the parameters studied including plasma glucose
levels. Angiography showed improvement in retinal changes following combined antidiabetic treatment. 相似文献
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S. Bhattacharya K. Sengupta S. Sengupta P. Mukhopadhyay A. Debnath P. Das 《Indian journal of clinical biochemistry : IJCB》1998,13(1):33-35
Summary Amoebiasis, caused by an enteric protozoanEntamoeba histolytica, is one of the major parasitic diseases of mankind. Current estimate suggests that the parasite infects about 10% of the
world population at any given time. There is an urgent need to characterize the antigenic molecules ofE. histolytica, and find out antigens which have both immunodiagnostic and prophylactic potential against amoebiasis. The results of somatic
antigen analysis, using sera from immune or infected individuals, indicated that the wholeE. histolytica trophozoites, are highly complex and heterogeneous in nature and both immunodiagnostic and immuno prophylaxis activity remain
mainly in a surface associated 29 kDa glycoprotein ofE. histolytica. Future studies at molecular level particularly, genes responsible for expression of this protein, their homology with other
proteins and structure analysis will give better understanding about this polypeptide. Studies on excretory secretory antigens,
clearly demonstrated thatE. histolytica like many organisms, also liberates certain antigenic moieties into the culture medium during in vitro cultivation and this
antigen has similar diagnostic values like the conventional somatic antigens. It is important that the ESA should be prepared
from the supernatant after collecting the cell and use for immunodiagnosis of amoebiasis. This is an additional source of
antigen which will help in carrying out more tests using the same reagents. Further studies are needed to clarify the location
of these molecules on the parasite, along with detailed biochemical and immunological characterization and their relation
with the pathogenesis.
This was presented at the symposium on “Recent Trends in Tropical Disease Research”, held at Sevagram on 5-6 September, 1997. 相似文献
33.
Utpal Mukhopadhyay 《Resonance》2004,9(3):33-41
In mathematics, we encounter various types of curves. Some of these curves possess very interesting backgrounds. In this article,
the historical backgrounds of some well-known curves have been discussed along with some other interesting features. 相似文献
34.
A review of educational policies and procedures in Botswana reveals that inclusion of learners with special educational needs (SENs) in regular classrooms is currently the main policy and school practice. However, there are variations in the way inclusion is being practiced and implemented throughout the country. The purpose of this present study was to examine the experiences of inclusion by learners with SENs in Botswana’s primary schools. Using a qualitative approach, 36 learners with SENs as well as 36 learners without SENs were engaged in twelve focus group discussions from six primary schools. Six focus group were for learners with SENs and the other six were for learners without SENs. Objectives of these focus group interviews were to gather day-to-day experiences of learners in general education classrooms since they were the recipients and participants of an inclusive practice. The findings revealed that although, learners with SENs had positive experiences about inclusion, they equally faced barriers in accessing curriculum. Implications of the findings are discussed in order to promote wider participation for learners with SENs in Botswana primary schools. 相似文献
35.
Benjamin C. Heddy Gale M. Sinatra Helena Seli Gita Taasoobshirazi Ananya Mukhopadhyay 《教育心理学》2017,37(5):565-581
The Teaching for Transformative Experience in Science (TTES) model has shown to be a useful tool to generate learning and engagement in science. We investigated the effectiveness of TTES for facilitating transformative experience (TE), learning, the development of topic interest and transfer of course concepts to other courses employing a quasi-experimental design. Our goal was to determine the effectiveness of TTES compared to an alternative teaching method in a course designed for academically at-risk undergraduate students. Specifically, we explored the impact of TTES for teaching about motivation in a college success course. The results showed that TTES generated TE outside of the biological sciences, increased learning, developed student interest and facilitated self-reported transfer to other courses. The findings have important implications for facilitating learning and motivation in academically at-risk college students, which may subsequently impact college student retention and academic success. 相似文献
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Moushumi Lodh Rajarshi Mukhopadhyay 《Indian journal of clinical biochemistry : IJCB》2016,31(1):121-124
We present three cases who presented to our Endocrinology OPD a few days apart with the common complaints of no or minimal development of secondary sexual characteristics. Although they had similar problems, investigations revealed a spectrum of different clinical, biochemical and genetic abnormalities. All the patients had otherwise normal anterior pituitary hormone secretion and sellar anatomy. One had a short Y chromosome, one was a Klinefelter syndrome and the other had no chromosomal abnormality. These findings along with absence of any detectable abnormality on pituitary imaging helped us diagnose these cases as Idiopathic hypogonadotropic hypogonadism. Treatment with testosterone showed marked improvement at 1 year follow up. 相似文献
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