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61.
The present study aims to assess and compare the biochemical oxidative stress markers in male smokers and non-smokers with chronic periodontitis. One hundred thirty-four male chronic periodontitis patients and 64 apparently healthy male volunteers were recruited for the study. The periodontal status was evaluated by measuring gingival index, plaque index, papillary bleeding index and clinical attachment loss using UNC-15 probe. The biochemical markers estimated were total antioxidant capacity, RBC-superoxide dismutase, glutathione peroxidase, vitamin C, malondialdehyde and C-reactive protein. The obtained results indicate higher oxidative stress in chronic periodontitis. Smokers with chronic periodontitis show significantly higher periodontal clinical parameters and relatively higher systemic oxidative stress. Vitamin C estimation may be an important biochemical parameter in conjunction with clinical parameters for diagnosis of chronic periodontitis in smokers.  相似文献   
62.
Whilst laboratory-on-chip cell separation systems using dielectrophoresis are increasingly reported in the literature, many systems are afflicted by factors which impede “real world” performance, chief among these being cell loss (in dead spaces, attached to glass and tubing surfaces, or sedimentation from flow), and designs with large channel height-to-width ratios (large channel widths, small channel heights) that make the systems difficult to interface with other microfluidic systems. In this paper, we present a scalable structure based on 3D wells with approximately unity height-to-width ratios (based on tubes with electrodes on the sides), which is capable of enriching yeast cell populations whilst ensuring that up to 94.3% of cells processed through the device can be collected in tubes beyond the output.  相似文献   
63.
Abdul Jamil Urfi 《Resonance》2013,18(5):468-474
Since evolution forms the core of modern biology, teaching about natural selection is extremely important as this equips the student to frame the ‘why’ questions properly and, at the same time, sharpens their understanding about a host of issues pertaining to behaviour, diversity and genetics.  相似文献   
64.
An experimental machine vision apparatus was used to identify and extract recyclable plastic bottles out of a conveyor belt. Color images were taken with a commercially available Webcam, and the recognition was performed by our homemade software, based on the shape and dimensions of object images. The software was able to manage multiple bottles in a single image and was additionally extended to cases involving touching bottles. The identification was fulfilled by comparing the set of measured features with an existing database and meanwhile integrating various recognition techniques such as minimum distance in the feature space, self-organized maps, and neural networks. The recognition system was tested on a set of 50 different bottles and provided so far an accuracy of about 97% on bottle identification. The extraction of the bottles was performed by means of a pneumatic arm, which was activated according to the plastic type; polyethylene-terephthalate (PET) bottles were left on the conveyor belt, while non-PET bottles were extracted. The software was designed to provide the best compromise between reliability and speed for real-time applications in view of the commercialization of the system at existing recycling plants.  相似文献   
65.
Chlorella vulgaris (CV) has been reported to have antioxidant and anticancer properties. We evaluated the effect of CV on apoptotic regulator protein expression in liver cancer-induced rats. Male Wistar rats (200∼250 g) were divided into eight groups: control group (normal diet), CDE group (choline deficient diet supplemented with ethionine in drinking water to induce hepatocarcinogenesis), CV groups with three different doses of CV (50, 150, and 300 mg/kg body weight), and CDE groups treated with different doses of CV (50, 150, and 300 mg/kg body weight). Rats were sacrificed at various weeks and liver tissues were embedded in paraffin blocks for immunohistochemistry studies. CV, at increasing doses, decreased the expression of anti-apoptotic protein, Bcl-2, but increased the expression of pro-apoptotic protein, caspase 8, in CDE rats, which was correlated with decreased hepatoctyes proliferation and increased apoptosis as determined by bromodeoxy-uridine (BrdU) labeling and terminal deoxynucleotidyl transferase mediated dUTP nick-end labeling (TUNEL) assay, respectively. Our study shows that CV has definite chemopreventive effect by inducing apoptosis via decreasing the expression of Bcl-2 and increasing the expression of caspase 8 in hepatocarcinogenesis-induced rats. Project supported by Department of Biochemistry, Faculty of Medicine, UKM Medical Center, Universiti Kebangsaan Malaysia, and the Malaysian Ministry of Science and Technological Innovation (MOSTI)  相似文献   
66.
建立知识社会   总被引:1,自引:0,他引:1  
人类社会正经历着向知识社会的转变;知识正日益成为经济发展和社会进步的核心因素.身处全球迈向知识社会的进程之中,我们目睹和亲历着世界性的合作、竞争、流动和创新.技术变革无疑是这一进程的强大驱动力之一;而在技术不断取得极大进步,知识与信息以空前的数量产生和极快的速度传播的同时,也存在着知识鸿沟或数字鸿沟现象.  相似文献   
67.
Since its inception 30 years ago, the then Department of Engineering Science, Institut Teknologi MARA (ITM) was given the responsibility of preparing all the students in the first year engineering programmes by giving enough knowledge in basic science and mathematics. The nation's vision to become a fully‐industrialised economy by the year 2020 required all institutes of higher learning (IHLs) in Malaysia to increase their intake of students in the science and technology courses, especially in engineering. However, at the upper secondary education level, students have the freedom to choose between the science‐based or non‐science combination of subjects. This has led to a dearth of science‐based students enrolling in IHLs. Because ITM believes that it is possible to educate individuals from various backgrounds, the engineering courses are open to students with a variety of academic qualifications. Special bridging courses were designed and created for such students since late 1996. The success or failure of the new courses can be assessed after the students have gone through the proper first year engineering courses which consist of Mathematics, Physics and Chemistry. This paper reports on a pilot study on the pioneer groups of students with variable entry qualifications to assess the effectiveness of the courses. The study involved the analysis of the students’ examination results as a performance indicator, and it was found that the bridging programme for non‐science students needed to be redesigned. It is also proposed that to improve the quality of the programme, and hence students’ performance, a regular review be conducted, student support activities be continued and to expand the use of self‐study materials.  相似文献   
68.
Thin slice studies have demonstrated that quick personality inferences of unknown others can be made fairly accurately. Utilizing focus group interviews, the current study examines thin sliced judgments and perceptions of six leaders in the context of goodness. Findings revealed that perceivers were able to form relatively accurate impressions of some leaders based on brief glimpses of nonverbal footage. Across all groups (Malaysian and Chinese) paralinguistic cues, dynamic cues and static cues were instrumental in the formation of positive perceptions of leaders in the context of goodness. These findings have implications for the areas of nonverbal behaviour, political communication, and personality judgement.  相似文献   
69.
70.
This laboratory activity was designed to strengthen our Food and Nutritional Science students’ knowledge of biochemistry concepts and the relationship between these concepts and food science. The result was a laboratory experience in which biochemistry concepts are taught using yogurt as a model, in order to link those concepts to food safety, an important area of food science. The students employed a colorimetric method to measure the lactase activity of bacterial strains found in commercial yogurts and were encouraged to relate the activity to bacterial lactic acid production, fermentation, and food safety. Students were assessed with pre‐ and post‐test exams, laboratory reports, class performance rubrics, and the Intrinsic Motivation Inventory (IMI). The result demonstrated that the students successfully completed the learning objectives and were motivated during the activity. This exercise could be used as a template for a simplified and engaging way to introduce food science majors, as well as other students, to complex biochemistry and molecular biology concepts using food, particularly yogurt, as a model.  相似文献   
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