The effect of extremely high glucose concentrations on 21 routine chemistry and thyroid Abbott assays: interference study     

Serap ?uhadar  Mehmet K?seo?lu  Yasemin ?inpolat  Güler Bu?dayc?  Murat Usta  Tuna Semerci 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2016,26(1):53-60

Introduction

Extremely high glucose concentrations have been shown to interfere with creatinine assays especially with Jaffe method in peritoneal dialysate. Because diabetes is the fastest growing chronic disease in the world, laboratories study with varying glucose concentrations. We investigated whether different levels of glucose spiked in serum interfere with 21 routine chemistry and thyroid assays at glucose concentrations between 17-51 mmol/L.

Materials and methods

Baseline (group I) serum pool with glucose concentration of 5.55 (5.44-5.61) mmol/L was prepared from patient sera. Spiking with 20% dextrose solution, sample groups were obtained with glucose concentrations: 17.09, 34.52, and 50.95 mmol/L (group II, III, IV, respectively). Total of 21 biochemistry analytes and thyroid tests were studied on Abbott c8000 and i2000sr with commercial reagents. Bias from baseline value was checked statistically and clinically.

Results

Creatinine increased significantly by 8.74%, 31.66%, 55.31% at groups II, III, IV, respectively with P values of < 0.001. At the median glucose concentration of 50.95 mmol/L, calcium, albumin, chloride and FT4 biased significantly clinically (-0.85%, 1.63%, 0.65%, 7.4% with P values 0.138, 0.214, 0.004, < 0.001, respectively). Remaining assays were free of interference.

Conclusion

Among the numerous biochemical parameters studied, only a few parameters are affected by dramatically increased glucose concentration. The creatinine measurements obtained in human sera with the Jaffe alkaline method at high glucose concentrations should be interpreted with caution. Other tests that were affected with extremely high glucose concentrations were calcium, albumin, chloride and FT4, hence results should be taken into consideration in patients with poor diabetic control.Key words: assay interference, glucose interference, preanalytical phase, creatinine, Jaffe kinetic assay, thyroid function tests  相似文献   

Editorial zum Themenheft: ,,Datenbanksysteme‘‘     

Theo H?rder 《Informatik - Forschung und Entwicklung》2007,11(2):125-126

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Critical factors influencing secondary school pupil’s decisions to study computing in tertiary education: Gender differences     

Evrikleia?Tsagala  Maria?KordakiEmail author 《Education and Information Technologies》2007,12(4):281-295

This paper aims to determine the factors affecting the decisions of both male and female secondary school pupils whether or not to pursue undergraduate studies in Computing. It is based on research conducted in Greece, on a sample of 248 pupils, 135 of whom were female. All were aged 17 and about to decide on their future undergraduate studies. Questionnaires were used, addressing issues in the following four main categories: a) the reasons pupils chose/rejected Computing, b) how family and friends, the media and the school environment contribute to their decision, c) how pupils perceived their future after studying Computing and d) how pupils perceived the profile of a computer professional in terms of gender.

Maria KordakiEmail:

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大学和学院组织模型:历史演化的视角   总被引：4，自引：1，他引：3  

马文·彼得森 《北京大学教育评论》2007,5(1):109-137

在过去五六十年里,高等教育研究者提出了多种高等教育组织模型,用它们来理解和解释美国大学和学院的组织行为。本文通过建立一个概念框架,试图解释它们的建立和发展过程。在概念框架中,“变化着的环境条件”是第一驱动力,它形成了“学校管理挑战”,影响和改变了“我们對对主要行业的概念”,从而通过它们间接地影响着大学和学院的运行机制。研究者提出的各种大学和学院组织模型就是从不同的侧面反映环境对组织的影响。  相似文献   

我将永远爱你     

许慧文 《英语沙龙》2011,(3)

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Seeing Iconic Gestures While Encoding Events Facilitates Children's Memory of These Events     

Suzanne Aussems  Sotaro Kita 《Child development》2019,90(4):1123-1137

An experiment with 72 three-year-olds investigated whether encoding events while seeing iconic gestures boosts children's memory representation of these events. The events, shown in videos of actors moving in an unusual manner, were presented with either iconic gestures depicting how the actors performed these actions, interactive gestures, or no gesture. In a recognition memory task, children in the iconic gesture condition remembered actors and actions better than children in the control conditions. Iconic gestures were categorized based on how much of the actors was represented by the hands (feet, legs, or body). Only iconic hand-as-body gestures boosted actor memory. Thus, seeing iconic gestures while encoding events facilitates children's memory of those aspects of events that are schematically highlighted by gesture.  相似文献   

Cross-cultural academic mentoring dyads: a case study     

Amber Daniel  Suzanne Franco  Noah L. Schroeder  Ada T. Cenkci 《Mentoring & Tutoring: Partnership in Learning》2019,27(2):164-189

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Under the hood and in the ‘hood: exploring significant academic development relationships     

Suzanne Le-May Sheffield  Tansy Jessop 《International Journal for Academic Development》2019,24(3):215-217

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Michael Heffernan  Heike J?ns 《Minerva》2008,46(1):169

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Differential effects of sociocultural variables on special education eligibility categories     

Andrs Barona  Suzanne P. Faykus 《Psychology in the schools》1992,29(4):313-320

The influence of sociocultural factors (ethnicity, socioeconomic status, father absence, and family size) on special education eligibility was examined for three ethnic groups. A multiple regression procedure was used to analyze the data on 300 students referred for evaluation and found to be either not eligible for services or eligible for services as mentally retarded or learning disabled. Results indicated that only socioeconomic status and ethnicity made a significant contribution to the prediction of all three groups. Individually, father absence and family size did not contribute to the prediction of special education eligibility. Results of this study suggest that legislative mandates to control for sociocultural factors in the determination of special education eligibility have been only partially successful.  相似文献