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991.
Public libraries have a huge potential to be creators and facilitators of social innovation in communities and society. Qualitative research based on interviews with 27 librarians showed that social innovation in libraries can take the form of educational and cultural activities, leisure and networking activities and social support services. The main goal of the research was to find out what factors support and make these innovations difficult in public libraries. A four-layer model of barriers and stimulators for social innovation is presented, which includes structural, local, organizational and personnel levels. The model could serve to inform librarians, their stakeholders and governments about all levels of barriers and stimulators connected to innovation of library services and social re-positioning of public libraries in the future.  相似文献   
992.
Students with Attention Deficit/Hyperactivity Disorder (ADHD) are a growing group served under special education services in many western societies. This article describes the history and current state of the services, as well as the assessment procedure. Our conclusion is that the status of students with ADHD in Finnish basic education (Grades 1 to 9) is still unclear. Based on the comparison of the prevalence and the population served in special education we can assume that this group is probably underserved in the Finnish school system. We also present findings from two recent studies among families with ADHD children in Finland. Family viewpoint can contribute to our knowledge and understanding about the diversity of the symptoms’ manifestation as well as the extent and completeness of the possible outcomes of the disorder. In the context of schooling, studying these families’ viewpoints can be of additional use in evaluating the present state of school practices in relation to institutional enactments established in educational acts. Future challenges about meeting the variety of pupils’ needs according to inclusive pedagogy are discussed.  相似文献   
993.
This mixed-method study examines Arizona principals’ capacity-building skills and practices in Tier III schools aimed at developing potential for sustained improvements in student outcomes. Data sources included surveys (62 individuals) and semistructured interviews (29 individuals) of principals and staff (e.g. teachers, instructional coaches, assistant principals) who participated in grant-funded leadership training over an 18-month period. The theoretical framework consisted of leadership in the sociocultural dimension (Ylimaki et al. in Leadersh Policy Sch 11(2):168–193, 2012) and capacity building for sustainable improvement in high-capacity Schools (Mitchell and Sackney in Sustainable improvement: building learning communities that endure. Sense Publishers, Rotterdam, 2009). Findings indicated that: (1) schools were not at high-levels of capacity building; (2) those schools in process of building capacity for sustainable improvement demonstrate a directive leadership approach; (3) school development towards high capacity focused on micro-level processes (e.g., professional learning communities); and (4) little attention was given to leadership in the socio-cultural dimension. Implications of the study suggest future research test a leadership development model for Tier III schools that links capacity building leadership and student achievement. The next generation of educational leaders must also have the knowledge, skills, dispositions, and analytical tools to lead schools in both the accountability culture and the macro socio-cultural dimension.  相似文献   
994.
The capability of 3D printing technologies for direct production of complex 3D structures in a single step has recently attracted an ever increasing interest within the field of microfluidics. Recently, ultrafast lasers have also allowed developing new methods for production of internal microfluidic channels within the bulk of glass and polymer materials by direct internal 3D laser writing. This review critically summarizes the latest advances in the production of microfluidic 3D structures by using 3D printing technologies and direct internal 3D laser writing fabrication methods. Current applications of these rapid prototyped microfluidic platforms in biology will be also discussed. These include imaging of cells and living organisms, electrochemical detection of viruses and neurotransmitters, and studies in drug transport and induced-release of adenosine triphosphate from erythrocytes.  相似文献   
995.
Serum CRP and uric acid levels were estimated in twenty-five patients with psoriasis (group III) before and after 12 weeks of treatment. Results were compared with a group of 25 normal subjects (group I) and a group of 25 patients of various skin diseases other than psoriatic lesion (group II). Mean value for CRP was found to be increased by more than 20 folds in patients with psoriasis, which was subsequently reduced to nearly 50% of the initial value after 12 weeks of treatment. These patients also showed hyperuricemia. Nearly 25% of these patients also exhibited arthritis. It is thus suggested that both CRP and uric acid levels should be monitored in patients with psoriasis.  相似文献   
996.
Twenty-four hour urinary albumin excretion (UAE) is considered as gold standard method for albuminuria measurement, but collection of 24-h urine is inconvenient. The aim of present study was to evaluate whether albumin: creatinine ratio (ACR) and urinary albumin concentration (UAC) in different spot urine samples correlate or not with 24-h UAE for screening of microalbuminuria in type 2 diabetic patients. We collected first morning void (FMV), random urine sample (RUS) and 24-h urine, separately on consecutive days from 104 type 2 diabetic patients. ACR and UAC in each spot urine sample compared with 24-h UAE with regard to Pearson correlation coefficient. Pearson’s correlation of albumin: creatinine ratio (ACR) with 24-h UAE was (r = 0.802 and 0.623) in first morning void (FMV) and random urine sample (RUS), respectively. Pearson’s correlation coefficient of urinary albumin concentration (UAC) compared with 24-h UAE was (r = 0.943 and 0.920), in FMV and RUS, respectively, P < 0.01. Results revealed that values in first morning void (FMV) were better correlated with 24-h urinary albumin excretion (UAE), than the values in random urine sample (RUS). We conclude that the first morning void (FMV) may be able to replace 24-h urine collection, preferably urinary albumin concentration (UAC) in the initial screening of microalbuminuria in diabetic patients.  相似文献   
997.
998.
Historians tend to treat science and medicine as having developed in parallel, and we maintain separate societies and journals, often giving primacy to science, at least for intellectual history. Yet much of "science" before circa 1800 was dependent on the organizations of medicine, and much of science now is promoted for the improvement of medical diagnoses and therapies. This Focus section unpicks some of the historical and historiographical relationships, recognizing the present prominence of biomedicine and the diminishing utility of distinctions between science, medicine, and technology.  相似文献   
999.
The aim of this study was to determine which physiological variables predict excellence in middle- and long-distance runners. Forty middle-distance runners (age 23 ± 4 years, body mass 67.2 ± 5.9 kg, stature 1.80 ± 0.05 m, VO(2max) 65.9 ± 4.5 ml · kg(-1) · min(-1)) and 32 long-distance runners (age 25 ± 4 years, body mass 59.8 ± 5.1 kg, stature 1.73 ± 0.06 m, VO(2max) 71.6 ± 5.0 ml · kg(-1) · min(-1)) competing at international standard performed an incremental running test to exhaustion. Expired gas analysis was performed breath-by-breath and maximum oxygen uptake (VO(2max)) and two ventilatory thresholds (VT(1) and VT(2)) were calculated. Long-distance runners presented a higher VO(2max) than middle-distance runners when expressed relative to body mass (P < 0.001, d = 1.18, 95% CI [0.68, 1.68]). At the intensities corresponding to VT(1) and VT(2), long-distance runners showed higher values for VO(2) expressed relative to body mass or %VO(2max), speed and oxygen cost of running (P < 0.05). When oxygen uptake was adjusted for body mass, differences between groups were consistent. Logistic binary regression analysis showed that VO(2max) (expressed as l · min(-1) and ml · kg(-1) · min(-1)), VO(2VT2) (expressed as ml · kg(-0.94) · min(-1)), and speed at VT(2) (v(VT2)) categorized long-distance runners. In addition, the multivariate model correctly classified 84.7% of the athletes. Thus, VO(2max), VO(2VT2), and v(VT2) discriminate between elite middle-distance and long-distance runners.  相似文献   
1000.
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