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21.
Nidhi Sharma Veena Garg Arpita Paul 《Indian journal of clinical biochemistry : IJCB》2010,25(2):193-200
Alloxan administration in male Swiss albino mice, induced diabetes by increasing blood glucose concentration and reducing
hepatic glycogen content as compared to normal control group. Besides, serum lipid profile parameters such as total-cholesterol,
triglyceride, low-density lipoprotein and very low-density lipoprotein-cholesterol were also elevated, whereas, the level
of high-density lipoprotein-cholesterol was reduced significantly (P<0.05) in diabetic mice. Treatment of diabetic animals
with crude ethanolic extract of bark of Prosopis cineraria (P. cineraria) for 45 days, significantly lowered blood glucose
level, elevated hepatic glycogen content and maintained body weight and lipid-profile parameters towards near normal range.
Declined activity of antioxidant enzymes and concentration of non-enzymatic antioxidants were also normalized by drug treatment,
thereby reducing the oxidative damage in the tissues of diabetic animals and hence indicating the anti-diabetic and antioxidant
efficacy of the extract. 相似文献
22.
P C Deshmukh Kaushal Jaikumar Pillay Thokala Soloman Raju Sudipta Dutta Tanima Banerjee 《Resonance》2017,22(6):577-596
Even as the theory of relativity is more than a hundred years old, it is not within easy reach of undergraduate students. These students have an insatiable urge to learn more about it even if the full machinery of the tools required to study the same is not within their comfortable reach. The recent detection of gravitational waves has only augmented their enthusiasm about the General Theory of Relativity (GTR), developed just over a hundred years now, encapsulated in Einstein’s Field Equations. The GTR provided a consistent formulation of the theory of gravity, removed the anomalies in the Newtonian model, and predicted spectacular natural phenomena which eventual experiments have testified to. This pedagogical article retraces some of the major milestones that led to the GTR and presents a simple numerical simulation of the GTR advance of the perihelion of planetary motion about the sun. 相似文献
23.
Sara E. Brownell Daria S. Hekmat-Scafe Veena Singla Patricia Chandler Seawell Jamie F. Conklin Imam Sarah L. Eddy Tim Stearns Martha S. Cyert 《CBE life sciences education》2015,14(2)
We present an innovative course-based undergraduate research experience curriculum focused on the characterization of single point mutations in p53, a tumor suppressor gene that is mutated in more than 50% of human cancers. This course is required of all introductory biology students, so all biology majors engage in a research project as part of their training. Using a set of open-ended written prompts, we found that the course shifts student conceptions of what it means to think like a scientist from novice to more expert-like. Students at the end of the course identified experimental repetition, data analysis, and collaboration as important elements of thinking like a scientist. Course exams revealed that students showed gains in their ability to analyze and interpret data. These data indicate that this course-embedded research experience has a positive impact on the development of students’ conceptions and practice of scientific thinking. 相似文献
24.
Narotam Sharma Veena Sharma Prem Raj Singh Shivani Sailwal Rajeev S. Kushwaha Rajesh K. Singh Satish C. Nautiyal Pankaj Mishra Tariq Masood R. K. Singh 《Indian journal of clinical biochemistry : IJCB》2013,28(3):305-308
Genitourinary tuberculosis is a disease of the genitourinary system which includes the entire urinary tract and reproductive system. Genital tuberculosis is an important cause of female infertility, especially in developing nations like India. In the present study, a total of 257 clinical specimens comprising of endometrial biopsy (109), endometrial curetting (42), menstrual blood (8), semen (17), placenta (11) and urine (70) were collected from patients and subjected for PCR, Culture and AFB detection. The endometrial biopsy, endometrial curetting, menstrual blood, semen, placenta, urine showed 30.2, 45.2,12.5, 5.8, 27.2, 31.4 %, positivity rate for tuberculosis by PCR, 7.3, 9.5, 25.0, 0, 9, 8.5 % by culture and 1.8, 2.3, 0, 0, 0, 2.8 % respectively by AFB smear. Being a novel, rapid technique, PCR is the method of choice for rapid diagnosis and management of genitourinary tuberculosis shared with the other concerned tests. This study reveals that genital tuberculosis can occur in any age group, however, the majority of patients were from reproductive age (nearly 75 % of them were from 20–45 years of age) group. 相似文献
25.
Conclusion Available evidence suggests that we can not dismiss the potential value of nutriceuticals in disease and inhibition of atherosclerosis.
Epidemiologic data suggest that antioxidant supplementation may be associated with a reduced risk of clinical events from
atherosclerosis; howere, interventional trials only support a role for vitamin E in this regard. Many studies suggest that
a link between fruit and vegetables in diet or the amounts of plasma antioxidant vitamins (ascorbic acid, tocopherols and
carotenoids) and risk of death from cancer or coronary heart disease. The usefulness of antioxidant for prevention of cardiovascular
disease is yet to be proven. However, studies offer important insights that together with the development of methods to identify
individuals most likely to benefit, provide hope to clinicians seeking to use antioxidant vitamins with safety and efficacy
for the treatment and prevention of cardiovascular disease. Only continued investigation into the mechanism (s) of action
of candidate agents will determine whether they hold promise as a therapeutic intervention and only then, they can be recommended
routinely to the patients. Thus, nutriceuticals are becoming more widely accepted as an adjunct to conventional therapies. 相似文献
26.
The whole theoretical framework of physics rests only on a few but profound principles. Wigner enlightened us by elucidating
that “It is now natural for us to try to derive the laws of nature and to test their validity by means of the laws of invariance,
rather than to derive the laws of invariance from what we believe to be the laws of nature.” Issues pertaining to symmetry,
invariance principles and fundamental laws challenge the most gifted minds today. These topics require a deep and extensive
understanding of both ‘quantum mechanics’ and the ‘theory of relativity’. We attempt in this pedagogical article to present
a heuristic understanding of these fascinating relationships based only on rather elementary considerations in classical and
quantum mechanics. An introduction to some fundamental considerations regarding continuous symmetries, dynamical symmetries
(Part 1), and discrete symmetries (Part 2) (parity, charge conjugation and time-reversal), and their applications in atomic,
nuclear and particle physics, will be presented. 相似文献
27.
In today's changed environment where the economy and industry are driven by customers, business is open to worldwide competition. Manufacturing firms have looked at employee performance improvement as a means to succeed. These findings advocate setting up priorities for employee performance improvement. This requires a continuous improvement training program. In this article, interpretive structural modeling is used to analyze interrelationships among performance appraisal factors to design and plan a training program for employees. 相似文献
28.
Avneet Kaur Pooja Negi Veena Sarna Rajendra Prasad Bir S. Chavan Anita Malhotra Gurjit Kaur 《Indian journal of clinical biochemistry : IJCB》2017,32(2):179-185
The present study was undertaken to study the impact of surgical menopause on oxidant and antioxidant status in relation to estrogen levels after 3 months of surgery. Total 130 women who had undergone total hysterectomy (TH) with or without bilateral salpingo-oophorectomy (BSO) were included in this study. The oxidant status was assessed by measuring plasma levels of malondialdehyde and antioxidant status was assessed by measuring superoxide dismutase, catalase, glutathione, glutathione peroxidase, estrogen, and Vitamin A, E and C levels. The malondialdehyde level was significantly increased (p < 0.05) in all women who underwent TH with or without BSO. Significant increased levels of superoxide dismutase were observed in women who underwent TH with BSO. The blood glutathione levels were significantly decreased in women after TH only but significantly increased in women who had undergone TH with BSO. The levels of estrogen, vitamin E and vitamin C were significantly decreased in women who underwent TH with BSO. The catalase, GPx and vitamin A did not differ significantly in all groups. The result suggests that surgical menopause is associated with oxidative stress which reiterates the fact that ovaries retain some function even after menopause. 相似文献