Estimation of Ischemia Modified Albumin (IMA) Levels in Patients with Acute Coronary Syndrome     

Prema Gurumurthy  Sai Krishna Borra  Rama Krishna Reddy Yeruva  Dolice Victor  Sai Babu  K. M. Cherian 《Indian journal of clinical biochemistry : IJCB》2014,29(3):367-371

Myocardial ischemia produces free radicals that catalyze a series of oxidative reactions that damage healthy tissues. The N-terminal sequence of albumin is one of the proteins modified by these highly reactive oxygen species and forms the ischemia modified albumin (IMA). This study involves investigations undertaken in different study groups to assess the levels of IMA. Mean serum IMA levels (U/mL) in patients with ST-segment elevated myocardial infarction (92.1 ± 10.6), non-ST-segment elevated myocardial infarction (87.3 ± 5.95) and unstable angina (UA) (88.9 ± 6.16) were significantly higher than non-cardiac chest pain (77.9 ± 6.69) and also healthy subjects (54.7 ± 17.2) (p < 0.001). IMA is a highly sensitive marker and has a high predictive value, which might prove the usefulness of this biomarker for early detection of myocardial ischemia. These data indicate a possible role of the IMA test in the early triage of patients with chest pain.  相似文献   

Research Goes Digital: Some Methods,Frameworks, and Issues     

Geraldine Torrisi-Steele  Victor C. X. Wang  Amy Sedivy-Benton  Carrie J. Boden-McGill 《The Reference Librarian》2015,56(4):239-258

Traditionally, librarians take a role in connecting researchers with resources. With the advent of the digital age, the nature of research is expanding; there are more, and different, sources of data, ways of collecting data, and methods of analyzing and interacting with data. If librarians are to remain relevant and able to serve their patrons, then they must engage in research as guides or even as partners in the research process. To do this, it is critical that librarians gain an understanding of the nature of research in the digital age and of the frameworks, methodologies, and issues related to digital research. The purpose of this article is to contribute to literature on digital research as it relates to librarianship.  相似文献   

Use before know-how: teaching with technology in a Mexican public school     

Judy Kalman  Victor Rendón 《International journal of qualitative studies in education》2014,27(8):974-991

In recent years, the Secretariat of Public Education in Mexico has supplied a significant number of schools with computers and connectivity, putting important resources into the purchase and installation of equipment. It is assumed that teachers will somehow naturally transition to using these tools and in fact, new curricular guidelines derived from international policy put them under a great deal of pressure to do so. This paper presents an up-close, qualitative look at one teacher’s efforts for incorporating technology into her history class and her process of constructing a working knowledge of using the computer, searching for ideas and materials on the Internet, and creating activities for her students. Equally important for incorporating technology into her teaching were the institutional and technical obstacles such as obsolete technology, insufficient connectivity, and school site constraints she confronted. Her case illustrates the complexity of using computer and Internet technologies in classroom settings.  相似文献   

关于具有测边导坑和有限岩石覆盖层的隧道开口的离散分析（英文）     

Chia Weng BOON  Chee Wei NEO  David Chew Chiat NG  Victor Chee Wee ONG 《浙江大学学报(A卷英文版)》2018,(4)

目的:针对新加坡的花岗岩地质结构,研究将典型马蹄形隧道挖掘成双拱隧道时岩石支撑的设计问题。利用离散元法分析侧边导坑对隧道主体开口的影响。创新点:1.基于平面应变假设,提出一个针对性的离散元模型以分析侧边导坑的设置对主体隧道支撑的影响;2.此模型适用于解决底下长跨度开口的支撑设计问题,如大众捷运系统隧道和紧贴式双孔隧道的建造,补充了传统经验主义的设计方法。方法:1.采用离散元法对马蹄形隧道开口支撑问题进行非连续分析;2.采用二维平面应变模型简化问题。结论:1.离散元法可用于分析有限岩石覆盖层的失效机制,单隧道支撑要求以及增加侧边导坑后的支撑要求;2.模型计算结果显示,侧边导坑的挖掘使得支柱总的螺栓连接作用力增加了一倍。  相似文献   

Designing and delivering skills transferability and employment mobility: the challenges of a market-driven vocational education and training system     

Victor Gekara  Darryn Snell 《Journal of Vocational Education & Training》2018,70(1):107-129

As job security declines and precarious employment arrangements become more prevalent, transferable skills have become vital for job seeking success. In recognition of this issue, many governments are seeking to redesign their training systems in ways that transferable skills become better emphasised. This paper examines the challenges of developing transferable skills among a nation’s workforce and the tensions that can emerge between training design intentions and training delivery outcomes when training delivery is marketised. Australia, where incremental training sector reforms have occurred since the late 1980s, serves as the context for this study. While training design occurs through a tripartite process involving employer, government and union representatives, training delivery is now determined in an open, deregulated market environment. Our analysis reveals a complex underlying design with an in-built intention of developing widely transferable skills, yet there exists significant concern about the actual training outcomes. We conclude that in an environment where VET delivery is user-choice driven with the aim of fulfilling specific employer skills needs the quality, depth and breadth of transferable skills are compromised.  相似文献   

Building community bonds,bridges, and linkages to promote the career readiness of high school students in the United States     

Victor M. Hernandez-Gantes  Sasha Keighobadi  Edward C. Fletcher Jr. 《Journal of Education & Work》2018,31(2):190-203

The career readiness of high school students has been a longstanding issue that has received renewed attention in recent years. To document an approach to promoting career readiness in the United States, we conducted an exploratory case study of a distinguished information technology career academy. Using the premises of capital building as a frame of reference, we found a community who viewed career readiness as a form of investment in human capital development. As such, a network of business partners collaborated with academy staff in providing school- and work-based learning opportunities for academy students. This approach was complemented by an emphasis on the development of social capital with social bonds, bridges, and linkages in place to sustain the network identity and development.  相似文献   

Caffeine ingestion changes time-motion and technical-tactical aspects in simulated boxing matches: A randomized double-blind PLA-controlled crossover study     

Victor Silveira Coswig  Paulo Gentil  Francine Irigon  Fabrício Boscolo Del Vecchio 《European Journal of Sport Science》2018,18(7):975-983

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Cross‐time attitudes,concept formation,and achievement in college freshman physics     

Victor L. Willson  Cheryl Ackerman  Cesar Malave 《科学教学研究杂志》2000,37(10):1112-1120

The relationships among science and engineering attitude, physics conceptual understanding, and physics achievement were explored for a population of college freshman engineering students over two semesters. Gender and SAT‐Quantitative measures were included as exogenous variables in a longitudinal path analysis. Attitude was theorized to predict achievement contemporaneously and at the next time point, while conceptual understanding was theorized to predict physics achievement contemporaneously and at the next time point. Each at one time was theorized to predict scores at the next time. A sample of 200 freshman engineering students participating in an integrated curriculum were assessed in September, December, and April (with a loss of 64 students) with the Force Concepts Inventory (FCI), Mechanics Baseline Test (MBT), and a locally developed attitude measure. The observed model indicated that the FCI predicted attitude at time 1 with no other paths between them, that FCI at time 1 predicted MBT at time 1 and time 2, FCI at time 2 predicted MBT at time 3, and MBT at time 1 predicted FCI at time 2. Gender and SAT‐Quantitative scores were predictive only of FCI and MBT at time 1. Results supported an interactive model of conceptual understanding and achievement, with attitude largely irrelevant to the process for this population. © 2000 John Wiley & Sons, Inc. J Res Sci Teach 37: 1112–1120, 2000  相似文献   

Guest editorial: Global science literacy: An earth system view     

Victor J. Mayer 《科学教学研究杂志》1997,34(2):101-105

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A polymeric micro-optical interface for flow monitoring in biomicrofluidics     

Francesca Sapuppo  Andreu Llobera  Florinda Schembri  Marcos Intaglietta  Victor J. Cadarso    Maide Bucolo 《Biomicrofluidics》2010,4(2)

We describe design and miniaturization of a polymeric optical interface for flow monitoring in biomicrofluidics applications based on polydimethylsiloxane technology, providing optical transparency and compatibility with biological tissues. Design and ray tracing simulation are presented as well as device realization and optical analysis of flow dynamics in microscopic blood vessels. Optics characterization of this polymeric microinterface in dynamic experimental conditions provides a proof of concept for the application of the device to two-phase flow monitoring in both in vitro experiments and in vivo microcirculation investigations. This technology supports the study of in vitro and in vivo microfluidic systems. It yields simultaneous optical measurements, allowing for continuous monitoring of flow. This development, integrating a well-known and widely used optical flow monitoring systems, provides a disposable interface between live mammalian tissues and microfluidic devices making them accessible to detection∕processing technology, in support or replacing standard intravital microscopy.  相似文献