排序方式： 共有53条查询结果，搜索用时 15 毫秒
31.
Pushpa Durgawale Sudhir Kanase Pramod S. Shukla Shubhangi Sontakke 《Indian journal of clinical biochemistry : IJCB》2005,20(2):174-177
Cerebrospinal fluid protein estimation is a routine diagnostic tool for various diseases. The proposed modified bromocresol
green (BCG) method is applicable to automated as well as manual measurements. Protein concentrations and absorbance at 600
nm are linearly related throughout a wide range of concentrations from 10 mg % to 2000 mg %. Ninety C.S.F. samples were analyzed
and results obtained by both the modified BCG method and routine pyrogallol red method were compared. An excellent co-relation
was observed (n=90, g=0.996, P<0.001). 相似文献
32.
Sunil B. Yadav Adinath N. Suryakar Anil D. Huddedar Pramod S. Shukla 《Indian journal of clinical biochemistry : IJCB》2006,21(1):152-156
Defective sperm function is the most common cause of infertility. A prospective study was carried out to correlate the concentration
of nitrite (the stable metabolite of nitric oxide) in seminal plasma with leukocytospermia, and sperm membrane integrity.
Total Fifty-seven normozoospermic subjects with and without leukocytospermia visiting the Infertility clinic at KH and MRC,
Karad, were included in the present study. Semen samples were checked for sperm concentration, total sperm count, sperm motility,
seminal leukocyte concentration and sperm membrane integrity as Hypoosmotic Swelling Test. Similarly the concentration of
nitrite in seminal plasma was measured by Griess reaction and total antioxidant power measured as ferric reducing ability
of plasma. The concentration of nitrite in seminal plasma was found to be raised with significantly increased leukocyte concentration
in semen. Also significantly lowered levels of total antioxidant power along with defective sperm function was observed. Our
results suggest that supplementary treatment of antioxidants with antibiotic for leukocytospermic infertile male patients
may improve the sperm membrane integrity. 相似文献
33.
Rimi Shukla Kiran Anand K. M. Prabhu P. Suryanarayana Murthy 《Indian journal of clinical biochemistry : IJCB》1995,10(2):119-121
Hypolipidemic effect of the water extract of the bark ofFicus bengalensis was investigated in alloxan induced diabetes mellitus in rabbits. Treatment for one month (50 mg/kg body weight/day) brought down the level of total serum cholesterol (TC) in subdiabetic and diabetic rabbits (five in each group) from 82±11 mg% and 118±10.6 mg% to 42.7±3.1 mg% and 51.7±4.7 mg% respectively. Low density lipoprotein cholesterol and very low density lipoprotein cholesterol values came down from 34±10 mg% and 95±24 mg% to 16±3 mg% and 29±4 mg% in subdiabetic and diabetic rabbits. Triacylglycerol level before treatment was 121±21.6 mg% and 416±70 mg% in subdiabetic and diabetic rabbits. Treatment brought it down to 45±5 mg% and 81±27.5 mg%. Glycosylated hemoglobin was brought down from 2.1±0.3% to 1.5±0.1% in subdiabetic group and from 4.28±0.5% to 2±0.3% in diabetic group, indicating that treatment with water extract effectively controlled blood sugar. After treatment with water extract serum lipid values were nearly equal to those in healthy controls (normal) in subdiabetic rabbits, while in diabetic group, the values were only slightly above those of normal. 相似文献
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Pushpa Durgawale Sangita Patil P. S. Shukla Ajit Sontakke Satish Kakade Sunil Yadav 《Indian journal of clinical biochemistry : IJCB》2009,24(1):30-35
Fasting samples of 914 subjects from healthy population were analyzed for total cholesterol, triglyceride and three major
fractions of lipoproteins i.e. high-density lipoprotein cholesterol, low lipoprotein cholesterol and very low-density lipoprotein
cholesterol. The values obtained were (in mg/dl) 165.7±30.2,88.36±31.2, 44.86±10.68, 101.66±29.8 and 18.11±7.35 respectively.
When these subjects were grouped according to the age and sex, no appropriate differences were observed between most of the
groups. Triglycerides were found to be low and HDL cholesterol was high in female when compared with male of similar age.
Beyond age 40 years cholesterol level and low density lipoprotein cholesterol was found to be gradually increased in case
of women. Minor difference was observed with dietary pattern. Present study suggests that clinical evaluation of patient should
be made on the basis of these reference values for Western Maharashtra population. 相似文献
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37.
Application of Tucatinib and Trastuzumab: Dual Anti HER2 Therapy Against HER2 Positive Breast Cancer
Sumanpreet Kaur Rajasri Bhattacharyya Dibyajyoti Banerjee Jaya Shukla 《Indian journal of clinical biochemistry : IJCB》2021,36(1):124
Synergism in action of tucatinib and trastumab is reported in breast cancer management. However, its molecular basis is yet to be determined. In this context we attempted to provide an explanation at the molecular level by performing in silico experimentation and coupling its result with already available published observations. Our study will provide basis for planning further experimental study for unravelling the truth. 相似文献
38.
Similes require two different pragmatic skills: appreciating the intended similarity and deriving a scalar implicature (e.g., “Lucy is like a parrot” normally implies that Lucy is not a parrot), but previous studies overlooked this second skill. In Experiment 1, preschoolers (N = 48; ages 3–5) understood “X is like a Y” as an expression of similarity. In Experiment 2 (N = 99; ages 3–6, 13) and Experiment 3 (N = 201; ages 3–5 and adults), participants received metaphors (“Lucy is a parrot”) or similes (“Lucy is like a parrot”) as clues to select one of three images (a parrot, a girl or a parrot-looking girl). An early developmental trend revealed that 3-year-olds started deriving the implicature “X is not a Y,” whereas 5-year-olds performed like adults. 相似文献
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Shailja Chambial Kamla Kant Shukla Shailendra Dwivedi Pankaj Bhardwaj Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2015,30(3):357-359
Lead interferes with a variety of body processes and is toxic to many organs and tissues including the heart, bones, intestines, kidneys, and reproductive and nervous systems. Routes of exposure to lead include contaminated air, water, soil, food, and consumer products. The possibility of lead exposure in humans is therefore of great significance from health point of view. Occupational exposure is a common known cause of lead poisoning in adults but current status of adults exposed otherwise is not known. School teachers representing wide local population were selected and asked to furnish information regarding possible lead exposure. Blood lead level (BLL) was estimated using anodic stripping voltammetry. The mean BLL was 6.89 ± 9.5 μg/dl (<3.5–>65 μg/dl) in representative adult population. Out of the total 16 % were found to be having BLL >10 μg/dl which has significantly decreased from leaded gasoline era. Those with increased BLL (>10 μg/dl) were found to have common determinants like usage of old metallic pipes for plumbing, water consumption without any purification system, usage of cosmetics and Ayurvedic/herbal medicines. 相似文献