Analysis of gene expression at the single-cell level using microdroplet-based microfluidic technology     

Mary P  Dauphinot L  Bois N  Potier MC  Studer V  Tabeling P 《Biomicrofluidics》2011,5(2):24109

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Fostering parents-professional collaboration for facilitating the school inclusion of students with ASD: design of the “ToGather” web-based prototype     

Mazon  Cécile  Etchegoyhen  Kattalin  Saint-Supery  Isabeau  Amestoy  Anouck  Bouvard  Manuel  Consel  Charles  Sauzéon  Hélène 《Educational technology research and development : ETR & D》2022,70(1):231-262

Educational technology research and development - In recent years, many psycho-educational technologies were studied to address the school-related difficulties encountered by students with autism...  相似文献   

Job Demands and Resources Experienced by the Early Childhood Education Workforce Serving High-Need Populations     

Farewell  Charlotte V.  Quinlan  Jennie  Melnick  Emily  Powers  Jamie  Puma  Jini 《Early Childhood Education Journal》2022,50(2):197-206

Early Childhood Education Journal - The early childhood education (ECE) workforce plays a key role in promoting early childhood development by their interactions with young children during...  相似文献   

Differences in Brain Activation Between Novices and Experts in Science During a Task Involving a Common Misconception in Electricity     

Steve Masson  Patrice Potvin  Martin Riopel  Lorie‐Marlène Brault Foisy 《Mind, Brain, and Education》2014,8(1):44-55

Science education studies have revealed that students often have misconceptions about how nature works, but what happens to misconceptions after a conceptual change remains poorly understood. Are misconceptions rejected and replaced by scientific conceptions, or are they still present in students' minds, coexisting with newly acquired scientific conceptions? In this study, we use functional magnetic resonance imaging (fMRI) to compare brain activation between novices and experts in science when they evaluate the correctness of simple electric circuits. Results show that experts, more than novices, activate brain areas involved in inhibition when they evaluate electric circuits in which a bulb lights up, even though there is only one wire connecting it to the battery. These findings suggest that experts may still have a misconception encoded in the neural networks of their brains that must be inhibited in order to answer scientifically.  相似文献   

The transfer of social exclusion and inclusion functions through derived stimulus relations     

Anita Munnelly  Georgina Martin  Charlotte Dack  Ann Zedginidze  Louise McHugh 《Learning & behavior》2014,42(3):270-280

Previous studies have found that social exclusion can cause distress to those excluded. One method used to study social exclusion is through a virtual ball-toss game known as Cyberball. In this game, participants may be excluded from or included in the ball-toss game and typically report lower feelings of self-esteem, control, belonging, and meaningful existence following exclusion. Experiments 1 and 2 sought to explore the transfer of feelings of exclusion and inclusion through stimulus equivalence classes. In both experiments, participants were trained to form two three-member equivalence classes (e.g., A1–B1, B1–C1; A2–B2, B2–C2) and were tested with novel stimulus combinations (A1–C1, C1–A1, A2–C2, C2–A2). Thereafter, participants were exposed to the Cyberball exclusion and inclusion games. In these games, one stimulus (C1) from one equivalence class was assigned as the Cyberball inclusion game name, whereas one stimulus (C2) from the other equivalence class was assigned as the Cyberball exclusion game name. In Experiment 2, participants were only exposed to the Cyberball exclusion game. During a subsequent transfer test, participants were asked to rate how included in or excluded from they thought they would be in other online games, corresponding to members of both equivalence classes. Participant reported that they felt they would be excluded from online games if the games were members of the same equivalence class as C2. In contrast, participants reported that they felt they would be included in online games if the games were members of the same equivalence class as C1. Results indicated the transfer of feelings of inclusion (Experiment 1) and feelings of exclusion (Experiments 1 and 2) through equivalence classes.  相似文献   

Seeing Scotland: creating visual imagery in an Ohio classroom     

Charlotte Fairlie 《Changing English: An International Journal of English Teaching》2004,11(2):205-211

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Training educational administrators in Central America     

Jean-François Bernède 《Prospects》1977,7(1):113-117

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A tapered channel microfluidic device for comprehensive cell adhesion analysis, using measurements of detachment kinetics and shear stress-dependent motion     

Rupprecht P  Golé L  Rieu JP  Vézy C  Ferrigno R  Mertani HC  Rivière C 《Biomicrofluidics》2012,6(1):14107-1410712

We have developed a method for studying cellular adhesion by using a custom-designed microfluidic device with parallel non-connected tapered channels. The design enables investigation of cellular responses to a large range of shear stress (ratio of 25) with a single input flow-rate. For each shear stress, a large number of cells are analyzed (500–1500 cells), providing statistically relevant data within a single experiment. Besides adhesion strength measurements, the microsystem presented in this paper enables in-depth analysis of cell detachment kinetics by real-time videomicroscopy. It offers the possibility to analyze adhesion-associated processes, such as migration or cell shape change, within the same experiment. To show the versatility of our device, we examined quantitatively cell adhesion by analyzing kinetics, adhesive strength and migration behaviour or cell shape modifications of the unicellular model cell organism Dictyostelium discoideum at 21 °C and of the human breast cancer cell line MDA-MB-231 at 37 °C. For both cell types, we found that the threshold stresses, which are necessary to detach the cells, follow lognormal distributions, and that the detachment process follows first order kinetics. In addition, for particular conditions’ cells are found to exhibit similar adhesion threshold stresses, but very different detachment kinetics, revealing the importance of dynamics analysis to fully describe cell adhesion. With its rapid implementation and potential for parallel sample processing, such microsystem offers a highly controllable platform for exploring cell adhesion characteristics in a large set of environmental conditions and cell types, and could have wide applications across cell biology, tissue engineering, and cell screening.  相似文献   

Δ-distance: A family of dissimilarity metrics between images represented by multi-level feature vectors     

Marta Rukoz  Maude Manouvrier  Geneviève Jomier 《Information Retrieval》2006,9(6):633-655

This article presents the Δ-distance, a family of distances between images recursively decomposed into segments and represented by multi-level feature vectors. Such a structure is a quad, a quin or a nona-tree resulting from a fixed and arbitrary image partition or from an image segmentation process. It handles positional information of image features (e.g. color, texture or shape). Δ-distance is the generalized form of dissimilarity measures between multi-level feature vectors. Using different weights on tree nodes and different distances between nodes, distances between trees or visual similarity between images can be computed based on the general definition of Δ. In this article, we present three Δ-based distance families: two families of distances between tree structures, called -distance( for Tree) and -distance ( for Segment), and a family of visual distances between images, called ( for Visual). The -distance visually compares two images using their tree representation and the other two distances compare the tree structures resulting from image segmentation. Moreover, we show how existing distances between multi-level feature vectors appear to be particular cases of the Δ-distance  相似文献   

Coherence in professional education: does it foster dedication and identification?     

Kåre Heggen  Lars Inge Terum 《Teaching in Higher Education》2013,18(6):656-669

This article examines the impact of professional education on students' dedication to and identification with a profession. The premise is that professional education is not only about knowledge acquisition and reasoning but also about attitudes and aspirations. In fostering dedication and identification, students' experiences of relevance seem to be important. The concept of coherence seen as an expression of relevance is introduced and measured by four kinds of interactions: Theory–practice interaction, teacher–student interaction, peer interaction and supervisor–student interaction. Analysis indicates that coherence, particularly as theory–practice interaction, peer interaction and supervisor–student interaction, has a significant impact on dedication to and identification with a profession. Longitudinal survey data – collected from students in colleges for teaching, nursing and social work – are analysed.  相似文献