A pump-free membrane-controlled perfusion microfluidic platform     

Vasiliy N. Goral  Elizabeth Tran  Po Ki Yuen 《Biomicrofluidics》2015,9(5)

In this article, we present a microfluidic platform for passive fluid pumping for pump-free perfusion cell culture, cell-based assay, and chemical applications. By adapting the passive membrane-controlled pumping principle from the previously developed perfusion microplate, which utilizes a combination of hydrostatic pressure generated by different liquid levels in the wells and fluid wicking through narrow strips of a porous membrane connecting the wells to generate fluid flow, a series of pump-free membrane-controlled perfusion microfluidic devices was developed and their use for pump-free perfusion cell culture and cell-based assays was demonstrated. Each pump-free membrane-controlled perfusion microfluidic device comprises at least three basic components: an open well for generating fluid flow, a micron-sized deep chamber/channel for cell culture or for fluid connection, and a wettable porous membrane for controlling the fluid flow. Each component is fluidically connected either by the porous membrane or by the micron-sized deep chamber/channel. By adapting and incorporating the passive membrane-controlled pumping principle into microfluidic devices, all the benefits of microfluidic technologies, such as small sample volumes, fast and efficient fluid exchanges, and fluid properties at the micro-scale, can be fully taken advantage of with this pump-free membrane-controlled perfusion microfluidic platform.  相似文献   

The mediastinal waltz - a representation of asymmetrical mediastinal anatomy     

Chan LK 《Anatomical sciences education》2011,4(3):174-175

This article describes a representation formed by a waltzing couple of two students that can be used to teach the asymmetrical anatomical relationships among the trachea, bronchi, pulmonary trunk, and the pulmonary arteries in the mediastinum.  相似文献   

A randomized trial comparing cadaveric dissection and examination of prosections as applied surgical anatomy teaching pedagogies     

Zong Jie Koh  Marcus Yeow  Dinesh Kumar Srinivasan  Yee Kong Ng  Gominda G. Ponnamperuma  Choon Seng Chong 《Anatomical sciences education》2023,16(1):57-70

Anatomy is an important component in the vertical integration of basic science and clinical practice. Two common pedagogies are cadaveric dissection and examination of prosected specimens. Comparative studies mostly evaluate their immediate effectiveness. A randomized controlled trial design was employed to compare both the immediate and long-term effectiveness of dissection and prosection. Eighty third-year medical students undergoing their surgical rotation from the Yong Loo Lin School of Medicine were randomized into two groups: dissection and prosection. Each participated in a one-day hands-on course following a similar outline that demonstrated surgical anatomy in the context of its clinical relevance. A pre-course test was conducted to establish baseline knowledge. A post-course test was conducted immediately after and at a one-year interval to evaluate learner outcome and knowledge retention. A post-course survey was conducted to assess participant perception. Thirty-nine and thirty-eight participants for the dissection and prosection groups, respectively, were included for analysis. There was no significant difference between mean pre-course test scores between the dissection and prosection groups [12.6 (3.47) vs. 12.7 (3.16), P > 0.05]. Both the mean immediate [27.9 (4.30) vs. 24.9 (4.25), P < 0.05] and 1 year [23.9 (4.15) vs. 19.9 (4.05), P < 0.05] post-course test scores were significantly higher in the dissection group. However, when adjusted for course duration [dissection group took longer than prosection group (mean 411 vs. 265 min)], these findings were negated. There is no conclusive evidence of either pedagogy being superior in teaching surgical anatomy. Based on learner surveys, dissection provides a greater learner experience.  相似文献   

The great upsurge of South Korea’s social movements in the 1960s     

Kim Dong‐Choon 《Inter-Asia Cultural Studies》2013,14(4):619-633

Abstract

I intend to show the characteristics and limitations of South Korea’s social movements in the 1960s and examine its formative potentialities in the growth of social movements thereafter. Whereas the 1960s in the Western world is characterized by the surge of ‘new social movements’ and waves of upheaval in the Third World, it would not be the case of South Korea. The ‘subject’ of the movements looks similar, but the context and raised issues proved markedly different. Some old‐school left‐wingers who conceived the strategy of socialistic national liberation survived the emergence of new ‘liberal’ generations in South Korea’s 1960s. The structural crisis of Korea’s anticommunist ruling class caused by the democratization movements and the growth of nationalism at the turn of the 1960s instigated the military coup of 1961, which finally brought Yushin dictatorship in 1972. Although South Korea’s social movements remained isolated from the world through the ‘long 60s’, it may be viewed as a significant part of the division of the ‘liberal consensus’ in the American‐led East‐Asian bloc.  相似文献   

How the Organizational Learning Process Mediates the Impact of Strategic Human Resource Management Practices on Performance in Korean Organizations     

Sei Hyoung Cho  Ji Hoon Song  Suk Chun Yun  Cheol Ki Lee 《Performance Improvement Quarterly》2013,25(4):23-42

The primary purpose of this research is to examine the structural relationships among several workplace‐related constructs, including strategic human resource management (HRM) practices, organizational learning processes, and performance improvement in the Korean business context. More specifically, the research examined the mediating effect of the organizational learning processes at three levels—individual, group, and organizational—to explain the relationship between strategic HRM practices and performance improvement. A total of 640 cases were used for data analysis, with general multivariate analyses and structural equation modeling. The results suggest that the learning processes at the three levels have a significant direct impact on organizational performance and that they also serve as a mediating interaction construct to maximize the effect of strategic HRM practices. The article provides conclusions, discusses the limitations of the research, and makes further recommendations.  相似文献