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11.
Non-alcoholic fatty liver disease and its more aggressive form, non-alcoholic steatohepatitis are entities that are becoming more and more interesting to the medical community in general. A total of 93 Non-alcoholic fatty liver disease patients (64 male and 29 female) within the age range between 28 to 63 years were studied. All of them showed elevated alanine aminotransferase level (104.07 ± 56.04). Aspartate aminotransferase level (58.13 ± 31.96) was elevated more than its normal level in 82% cases and AST to ALT ratio was found 0.59 ± 0.26. Predisposing factors were diabetes mellitus (37%), obesity (13%) and hyperlipidemia (41%). In addition, 32% of the subjects were overweight.18% of the patients had elevated serum bilirubin. Our findings recommend a lower cutoff value than suggested by the World Health Organization for overweight and obesity among this racial-ethnic group.  相似文献   
12.
Abstract

I wish to propose a general definition of empire that does not tie it with annexation and occupation of foreign territories and, therefore, is able to capture the new forms of indirect and informal control that have become common in recent decades. The imperial prerogative, I suggest, is the power to declare the colonial exception. Everyone agrees that nuclear proliferation is dangerous and should be stopped. But who decides that India may be allowed to have nuclear weapons, and also Israel, and may be even Pakistan, but not North Korea or Iran? We all know that there are many sources of international terrorism, but who decides that it is not Saudi Arabia or Pakistan but the regime of Saddam Hussein in Iraq that must be overthrown by force? Those who claim to decide on the exception are indeed arrogating to themselves the imperial prerogative.  相似文献   
13.
We, the Editors and Publisher of The International Journal of the History of Sport, have retracted the following article:

Amitava Chatterjee (2015), The Man Arrives: Breaking Off the Notion of Effeminacy in Colonial Bengal. The International Journal of the History of Sport, 32:3, pages 409–421.

The reason for retraction is significant overlap with the following previously published sources, which include the author’s own work, without appropriate acknowledgement:

Amitava Chatterjee (2015), From courtyard sport to competitive sport: evolution of wrestling in colonial Bengal. Sport in Society; 18:1; pages 1–16.

Boria Majumdar (2003), The Vernacular in Sport History. The International Journal of the History of Sport, 20:1; pages 107–125.

We have been informed in our decision-making by our policy on publishing ethics and integrity and the Committee on Publishing Ethics (COPE) guidelines on retractions. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as ‘Retracted’.  相似文献   
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15.
In this two part article I try to convey some of the variety and excitement involved in the application of mathematics to engineering problems; to provide a taste of some actual mathematical calculations that engineers do; and finally, to make clear the distinctions between the applied subject of engineering and its purer parents, which include mathematics and the physical sciences. Two main points of this article are that in engineering it is approximation, and not truth, that reigns; and that an engineer carries a burden of responsibility that mathematicians and scientists are spared. In this first part, I present my views on how engineering differs from mathematics and the physical sciences, and describe what I consider the workhorses of engineering calculations.  相似文献   
16.
Present study aimed to evaluate the protective role of the aqueous extract of Phyllanthus niruri (P. niruri) against nimesulide-induced hepatic disoder in mice by determining levels of glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) and alkaline phosphatase (ALP) in serum and also by measuring the hepatic content of the antioxidant enzymes, superoxide dismitase (SOD) and catalase (CAT); the free radical scavenger, reduced glutathione (GSH) and thiobarbituric acid reacting substances (TBARS). Aqueous extract of P. niruri was administered either orally or intraperitoneally in different doses and times as needed for the experiments. Intraperitoneal of the extract (100 mg/kg body weight for seven days) reduced nimesulide (750 mg/kg body weight for 3 days) induced increased levels of GOT (37.0±1.8 units/ml in control group vs. 91.8±2.0 units/ml in nimesulide treated group vs. 35.0±1.0 units/ml in extract treated group), GPT (30.0±2.1 units/ml in control group vs. 88.4±2.9 units/ml in nimesulide treated group vs. 34.1±1.8 units/ml in extract treated group), and ALP (7.86±0.47 KA units/ml in control group vs. 23.80±0.60 KA units/ml in nimesulide treated group vs. 7.30±0.40 KA units/ml, in extract treated group) to almost nomal. In addition, P. niruri restored the nimesulide induced alterations of hepatic SOD (550±20 units/mg total protein in control group vs. 310±13 units/mg total protein in nimesulide treated group vs. 515±10 units/mg total protein in extract treated group), CAT (99.5±2 units/mg total protein in control group vs. 25.0±1.5 units/mg total protein in nimesulide treated group vs. 81.0±0.8 units/mg total protein in extract treated group), GSH (90±3 nmoles/mg total protein in control group vs. 17±4.2 nmoles/mg total protein in nimesulide treated group vs. 81±1 nmoles/mg total protein in extract treated group) and TBARS (measured as MDA, 36.6±3.0 nmoles/g liver tissue in control group vs. 96.3±5.2 nmoles/g liver tissue in nimesulide treated group vs. 41.2±1.7 nmoles/g liver tissue in extract treated group) contents. Dose-dependent studies showed that the herb could protect liver even if the nimesulide-induced injury is severe. Intraperitoneal administration of the extract showed better protective effect than oral administration. Combining all, the data suggest that P. niruri possesses hepatoprotective activity against nimesulide-induced liver toxicity and probably acts via an antioxidant defense mechanism. To the best of our knowledge, this is the first report of the hepatoprotective action of P. niruri against nimesulide induced liver damage.  相似文献   
17.
ABSTRACT

Purpose

This paper is concerned with the impact of the University of California Cooperative Extension (UCCE) on regional productivity in California agriculture. UCCE is responsible for agricultural research and development (R&D), and dissemination of agricultural know-how in the state.  相似文献   
18.
Several geospatial approaches have been used to characterize physical activity during recess using global positioning system (GPS) data. GPS and accelerometer data from 23 children collected during recess were analyzed using four previously used approaches: (1) dot map, (2) fishnet grid, (3) hot spot analysis, which determines clusters of high/low intensity values, and (4) zonal approach wherein the schoolyard was divided into zones to determine the time and intensity in each zone. Results from each method were compared to each other and to video observation. Hot spot analysis revealed clusters of high-intensity values, which were supported by dot and grid maps and video. However, the zonal approach revealedpatterns in where children play that were not always comparable tovideo, potentially due to missing GPS data. Recommendations for the use of these methods in future research are discussed.  相似文献   
19.
This study was conducted to evaluate whether microalbuminuria on admission and after 24 hrs of admission to intensive care unit (ICU) predicts outcome as well as the Acute Physiology and Chronic Health Evaluation (APACHE) II severity illness score, the current accepted method of doing so. The study was carried out in a 20 bed mixed medical-surgical ICU of a tertiary care hospital. Of 525 consecutive adult patients with ICU stay of more than 24 hrs, 238 were included for the study. Patients with pregnancy, menstruation, anuria, macroscopic hematuria, urinary tract infection, marked proteinuria due to renal and post-renal structural diseases, were excluded. Spot urine samples were collected on admission to ICU and 24 hrs thereafter. Urine albumincreatinine ratio (ACR) was measured on ICU admission (ACR1) and after 24 hrs (ACR2) and expressed in mg/g. Patient demographics were noted on admission. For disease severity scoring, APACHE II scores were calculated. Each patient was followed up throughout their ICU stay for a maximum of 28 days and the following outcome data were obtained: ICU length of stay and ICU mortality. Of the 238 patients, 196 survived while 42 patients died in the ICU. Non-survivors had a significantly higher median ACR2 [162.7 mg/g (IQR 69.5–344.3)] in comparison to the survivors who had a median ACR2 = 54.4 mg/g (IQR 19.0–129.1) (P< 0.0001). The median ACR1 [161.0 mg/g (IQR 29.0–369.3)] of non-survivors was higher than the median ACR1 [80.4 mg/g (IQR 35.1–167.6)] of survivors but failed to reach statistical significance (P= 0.0948). In a receiver operating characteristic curve (ROC) analysis, ACR2 emerged as the best indicator of mortality [(area under curve (AUC) of ACR2 = 0.71 > AUC (ACR1) =0.58 > AUC (ΔACR) =0.55] similar to the currently used APACHE II scores (AUC = 0.78) (P=0.3). At a cutoff of 101 mg/g, ACR2 had a sensitivity of 69%, specificity of 67%, positive predictive value of 31% and a negative predictive value of 91% for predicting mortality in the critically ill patients. Absence of significant microalbuminuria at 24 hrs of ICU admission may help to predict survival in the ICU.  相似文献   
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