排序方式： 共有51条查询结果，搜索用时 15 毫秒
41.
Shailja Misra Bhattacharya K. Tyagi R. K. Chatterjee 《Indian journal of clinical biochemistry : IJCB》1997,12(1):35-39
Thyroid antibodies are commonly utilized in the assessment and diagnosis of autoimmune thyroid disorders. We compared the
measurements of antithyroglobulin and antithyroidperoxidase antibodies by enzyme immunoassay with that of the conventional
agglutination method. This fully automated enzyme immunoassay is more specific and cost effective than the agglutination method.
Further this is a very quantitative and rapid method producing results in two hours as compared to at least twenty=four hours
required by the conventional method. Antithyroidperoxidase antibodies determined by enzyme immunoassay are more specific and
sensitive in the diagnosis of Hashimoto's thyroiditis than the antithyroglobulin antibodies. 相似文献
42.
Specific binding and magnetic concentration of CD8+ T-lymphocytes on electrowetting-on-dielectric platform 总被引：1，自引：0，他引：1
In the quest to create a low-power portable lab-on-a-chip system, we demonstrate the specific binding and concentration of human CD8+ T-lymphocytes on an electrowetting-on-dielectric (EWOD)-based digital microfluidic platform using antibody-conjugated magnetic beads (MB-Abs). By using a small quantity of nonionic surfactant, we enable the human cell-based assays with selective magnetic binding on the EWOD device in an air environment. High binding efficiency (～92%)of specific cells on MB-Abs is achieved due to the intimate contact between the cells and the magnetic beads (MBs) produced by the circulating flow within the small droplet. MBs have been used and cells manipulated in the droplets actuated by EWOD before; reported here is a cell assay of a clinical protocol on the EWOD device in air environment. The present technique can be further extended to capture other types of cells by suitable surface modification on the MBs. 相似文献
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Chatterjee S Dhar S Sengupta B Ghosh A De M Roy S Chakrabarti S 《Indian journal of clinical biochemistry : IJCB》2010,25(3):260-272
Polycyclic aromatic hydrocarbons of tobacco require activation by phase I enzymes, such as cytochrome-P4501A1 (CYP1A1) to
become an ultimate carcinogen, which are subjected to detoxification by phase II enzymes, especially glutathione S-transferases (GSTs). A study was designed to find whether genetic predisposition are risk modifiers of oral pathologies.
The study included 102 cases with Oral Cancers (OCs), 68 cases with nonmalignant pathologies, 100 cases as control group.
GSTM1 null genotype was associated with increased risk of OCs but not with benign pathologies. Deleted GSTT1 was associated
with all pathologies. Both m1m2 and m2m2 polymorphisms of CYP1A1 were associated with oral pathologies. 相似文献
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Despite considerable progress made, a significant proportion of children continue to drop out before reaching secondary school in India. This study investigates factors influencing parental decision-making with regard to children's secondary schooling in the context of a rural area of Uttar Pradesh. The study finds that cost, distance to the nearest secondary school, membership in traditionally marginalised social groups, and being a girl child have a significant effect on a child's chance of transition. It also finds that factors influencing participation at the primary level may influence the transition decision, having key implications for education policy formulation across education levels. 相似文献
46.
Arun Kumar Singh Sunita Tiwari Abhishek Gupta Kamla Kant Shukla Kumar Gaurav Chhabra Achileshwar Pandey Aditya Bhushan Pant 《Indian journal of clinical biochemistry : IJCB》2015,30(3):255-262
Metabolic syndrome (MetS) is a cluster of interrelated common clinical disorders. The role of resistin in insulin sensitivity and MetS is controversial till date. So, the aim of the present study was to investigate the relationship of plasma resistin levels with markers of the MetS in Indian subjects. In a case control study, total 528 subjects were selected for the study. 265 (194 male and 71 female) were cases (with MetS) and 263 (164 male and 99 female) were controls (without MetS). Required anthropometric measurements and calculations were carried out accordingly. All the Biochemical estimations were carried out according to standard protocol. Resistin level was measured by the standard protocol (By ELISA i.e. enzyme linked immunosorbent assay) as illustrated in the kit. Insulin level was also measured by the standard protocol as illustrated in the kit and insulin resistance was calculated by the standard procedures. Plasma resistin levels were significantly higher in cases compared with controls (male = 13.05 ± 4.31 vs. 7.04 ± 2.09 ng/ml; p ≤ 0.001 and female = 13.53 ± 4.14 vs. 7.42 ± 2.30 ng/ml; p ≤ 0.001). Plasma resistin levels were well correlated with waist circumference, glucose, triglycerides, waist/hip ratio, systolic and diastolic blood pressure, high density lipoprotein, total cholesterol, serum low density lipoprotein, serum very low density lipoprotein, insulin and insulin resistance. Plasma resistin levels were elevated in presence of the MetS and were associated with increased metabolic risk factors. 相似文献
47.
Rebecca McLaughlan Ishita Chatterjee 《The International Journal of Art & Design Education》2020,39(3):550-564
Good teaching requires pedagogical dynamism: a willingness to vary one’s teaching approach relative to the context (and cohort) at hand, and to any new challenges that may arise from that context. This requires that teachers obtain a broad knowledge of teaching strategies and tactics. Given the demands of contemporary higher education, finding the time to obtain this knowledge can pose a challenge to full‐time academics. This is exacerbated in the case of part‐time and practitioner‐teachers who often work in varying degrees of isolation from the communities of learning to which they contribute. An analysis of the teaching practices of eight high‐performing practitioner‐teachers, alongside data obtained from 74 students, within a master’s‐level architectural course at a large Australian university, has been used to delineate five strategies for optimising student learning within the architecture studio. These include: setting up a challenge that clearly articulates the role of the student within it; early and frequent assessment tasks to assist students in rapid skill development and reflective practice; communicating clear expectations around performance; facilitating a strong peer culture; and enhancing motivation via high expectations. This article details the tactics by which these strategies can be achieved. This article delivers directly applicable advice for architectural educators, but it also provides practical insight into the specifics of architectural teaching that may assist educators working in other disciplines. 相似文献
48.
Anindya Chatterjee 《Resonance》2005,10(5):39-53
In this part of the article I begin with somewhat more advanced mathematics as compared to the first part. I then move on
to discuss insights, hierarchies of models, levels of approximation, models that are plain bad, and finally the role of truth.
Anindya Chatterjee is in the Department of Mechanical Engineering, IISc. His interests are in dynamics, in particular non-linear
dynamics. 相似文献
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Disha Banerjee Debarati Ghosh Anindita Chatterjee Swagata Sinha Krishnadas Nandagopal 《Indian journal of clinical biochemistry : IJCB》2012,27(1):46-51
GARS–AIRS–GART is crucial in studies of Down syndrome (DS)-related mental retardation due to its chromosomal location (21q22.1), involvement
in de novo purine biosynthesis and over-expression in fetal DS brain postmortem samples. GARS–AIRS–GART regions important for structure–function were screened for mutations that might alter protein levels in DS patients. Mutation
screening relied on multiplex/singleplex PCR-based amplification of genomic targets followed by amplicon size determination/fingerprinting.
Serum protein samples were resolved by SDS-PAGE and immunoblotted with a GARS–AIRS–GART monoclonal antibody. No variation
in amplicon size/fingerprints was observed in regions encoding the ATP-binding, active site residues of GARS, the structurally
important glycine-rich loops of AIRS, substrate-binding, flexible and folate-binding loops of GART or the poly-adenylation
signal sequences. The de novo occurrence or inheritance of large insertion/deletion/rearrangement-type mutations is therefore
excluded. Immunoblots show presence of GARS–AIRS–GART protein in all patient samples, with no change in expression levels
with respect to either sex or developmental age. 相似文献